التأثيرات التطورية السمية لكلوتامات أحادي الصوديوم على النمو والتركيب النسجي لعدسة العين في مواليد الفأر الأبيض السويسري Mus musculus = The Toxic Developmental Effects of Monosodium Glutamate on the Growth and Histological Structure of the Eye Lens in the Offspring Albino Swiss Mouse Mus Musculus

2016 ◽  
Vol 11 (4) ◽  
pp. 98-105
Author(s):  
ماجدة نوري إبراهيم ◽  
سميرة عبد الحسين عبد الله
2018 ◽  
Vol 54 (2) ◽  
pp. 84 ◽  
Author(s):  
Widayati Agustina ◽  
Widjiati Widjiati ◽  
Alfiah Hayati

This study aimed to determine the effects of red fruit (Pandanus conoideus Lam) oil on MDA levels and spermatozoa quality in mice (Mus musculus) exposed to MSG. The quality includes motility, viability, concentration, and morphology of spermatozoa. This experimental study used randomized post-test only control group design. The subjects of this study were 25 mice (Mus musculus), divided into 5 groups (5 mice per group). K- group received distilled water for 35 days. K+ group received 4 mg/g BW MSG for 21 days. P1, P2, and P3 treatment groups received 4 mg/g BW MSG for 21 days and 0.02; 0.04; 0.08 ml/g BW red fruit oil, respectively, from day 22 to 35. The results showed that mean spermatozoa morphology in K-, K+, P1, P2, P3 groups were as follows: 0.86; 0.56; 0.67; 0.61; and 0.87 (%). The spermatozoa concentrations were sequentially as follows: 21; 10; 15; 32,8,19 (107 cells/ml). The spermatozoa's vitalities were as follows: 0,64; 0,14; 0,24; P2: 0.36; 0.68 (%). MDA levels were respectively: 0.29; 0.60; 0.35; 0.23; and 0.19 (nm). As a conclusion, testicular MDA levels in mice exposed to MSG and given with red fruit oil were lower than those in mice exposed to MSG without receiving red fruit oil. The quality of spermatozoa in mice exposed to MSG and receiving red fruit oil was higher than that of mice exposed to MSG without being given with red fruit oil.


2014 ◽  
Vol 11 (3) ◽  
pp. 1089-1093
Author(s):  
Baghdad Science Journal

This study was designed to identify the extent of the effect of drug Acetylsalicylic acid (aspirin) on histological structure of liver in Swiss albino mice Mus musculus.(16) mice were used and divided into two groups. The first groupwas orally treated with )0.5ml(of aspirinat concentration of (50 mcg / kg) and the second group was considered as control group Treated with distiled water lasted for 30 days. Treatment with Aspirin led to the occurrence of histopathological cases included liver necrosis ,cellular infilitration, congestion in central vein and a case of Hemorrhage. The results also showed the absence of radial arrangement of the constituents of hepatic cells from tissue due to these changes with the control group. From the above results, it coulde be concluded that the drug aspirin had a negative effect on liver of Swiss albino


1985 ◽  
Vol 22 (1) ◽  
pp. 55 ◽  
Author(s):  
F. P. Rowe ◽  
A. Bradfield ◽  
R. J. Quy ◽  
T. Swinney

2020 ◽  
Vol 4 (1) ◽  
pp. 34
Author(s):  
Rizki Bunaya ◽  
Ilhami Romus ◽  
Fajri Marindra Siregar ◽  
Desby Juananda

Background: Immobilization stress is one method of stress induction on experimental animals. It affects the psychology and physical of experimental animals and is the recommended method for assessing changes in histological structure damage. The purpose of research was to analyze the effect of immobilization stress on gastric mucosal in mice.Materials and Methods: This research was experimental with post-test-only control group design. Twenty white mice (Mus musculus) male Swiss Webster strains were used in this study and divided into 4 groups: control, immobilization stress 14 days, immobilization stress 21 days, immobilization stress 28 days. Mice were given immobilization stress using 50 cc syringes for 2 hours every day for 14 days, 21 days and 28 days. Gastric mucosal damage in mice was analyzed under a microscope with of 10 fields of view in each sample. Data were analyzed using the Kruskal Wallis test and Mann Whitney test.Results: Gastric mucosal damage score were 0 in control, 1.42±0.265 in 14 days, 1.82±0.265 in 21 days, and 2.54±0.05 in 28 days. There was significant difference between each group (p<0.05), while the greatest damage was found in the 28 days group.Conclusion: These result indicated that immobilization stress caused gastric mucosal damage and the degree of damage is in accordance with duration of stress.Keywords: gastric mucosal, immobilization, stress


1970 ◽  
Vol 4 (2) ◽  
pp. 82-100
Author(s):  
Ummi Hiras Habisukan

Sweeteners are one of the components which are often added to foodstuffs. Synthetic sweetenersare widely used in the society is sodium cyclamate. The purpose of this study was to determine thesodium cyclamate on the histological structure of the glomerulus of mice (Mus musculus). Thisresearch used 12 male mice (Mus musculus) with Completely Randomized Design (CRD) so thereare 4 groups (control, PI: 0,55 mg/grbb, p2: 1,1 mg/grbb, and p3: 1,65 mg/grbb) with 3 replicationsfor 24 days. Parameters observed were edema and comparison of area glomerulus with Bowmancapsule. The result showed that sodium cyclamate had effect to edema and tended to areaglomerulus with Bowman capsule comparization. Based on the research could be concluded thatsodium cyclamate had effect to renal histopathology. This research will be used as media inlearning process.


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