scholarly journals Protective Effect of Apis dorsata Honey against Chronic Monosodium Glutamate-induced Testicular Toxicity in Mus musculus mice,

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Epy Muhammad Luqman ◽  
Aditya Tri Ananda ◽  
Widjiati Widjiati ◽  
Viski Fitri Hendrawan
2021 ◽  
Vol 35 (1) ◽  
pp. 9-15
Author(s):  
Vikas Sharma ◽  
Nagendra S Chauhan ◽  
Umesh K Patil ◽  
Vinod Kumar Dixit

2018 ◽  
Vol 54 (2) ◽  
pp. 84 ◽  
Author(s):  
Widayati Agustina ◽  
Widjiati Widjiati ◽  
Alfiah Hayati

This study aimed to determine the effects of red fruit (Pandanus conoideus Lam) oil on MDA levels and spermatozoa quality in mice (Mus musculus) exposed to MSG. The quality includes motility, viability, concentration, and morphology of spermatozoa. This experimental study used randomized post-test only control group design. The subjects of this study were 25 mice (Mus musculus), divided into 5 groups (5 mice per group). K- group received distilled water for 35 days. K+ group received 4 mg/g BW MSG for 21 days. P1, P2, and P3 treatment groups received 4 mg/g BW MSG for 21 days and 0.02; 0.04; 0.08 ml/g BW red fruit oil, respectively, from day 22 to 35. The results showed that mean spermatozoa morphology in K-, K+, P1, P2, P3 groups were as follows: 0.86; 0.56; 0.67; 0.61; and 0.87 (%). The spermatozoa concentrations were sequentially as follows: 21; 10; 15; 32,8,19 (107 cells/ml). The spermatozoa's vitalities were as follows: 0,64; 0,14; 0,24; P2: 0.36; 0.68 (%). MDA levels were respectively: 0.29; 0.60; 0.35; 0.23; and 0.19 (nm). As a conclusion, testicular MDA levels in mice exposed to MSG and given with red fruit oil were lower than those in mice exposed to MSG without receiving red fruit oil. The quality of spermatozoa in mice exposed to MSG and receiving red fruit oil was higher than that of mice exposed to MSG without being given with red fruit oil.


2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Amira El Arem ◽  
Lamia Lahouar ◽  
Emna Behija Saafi ◽  
Amira Thouri ◽  
Fatma Ghrairi ◽  
...  

Author(s):  
Okukwe Obode ◽  
Oluwatoyin Okafor ◽  
Ochuko Erukainure ◽  
Atinuke Ajayi ◽  
Yewande Suberu ◽  
...  

Abstract: The protective effect of a developed drink from blends of selected fruits on the sperm quality of alloxan-induced diabetic rats was investigated.: Diabetes was intraperitoneally induced with alloxan; the formulated drink blend was orally administered 2.5 or 5 mL/day. Treatment lasted for 14 days and the rats were humanely sacrificed by cervical dislocation. The antioxidant status via assessment of reduced glutathione (GSH), catalase (CAT), superoxide dismutase (SOD) and lipid peroxidation (LPO) was carried out on the testis, while sperm cells were analyzed for sperm motility, counts and abnormality.: Induction of diabetes led to a significant (p<0.05) decrease in GSH level, elevated SOD and CAT activities, significant (p<0.05) decrease in the sperm quality parameters studied. However, treatment with the formulated drink led to a significant (p<0.05) reduction of LPO, SOD and CAT activities as well as increase in GSH level.: This study shows an improvement in testicular antioxidant activities and sperm qualities by single and double doses of the formulation, suggesting its protective potential against testicular toxicity in diabetic rats.


2014 ◽  
Vol 28 (11) ◽  
pp. 515-521 ◽  
Author(s):  
Iman O. Sherif ◽  
Azza Abdel-Aziz ◽  
Osama M. Sarhan

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