G211 Development of a New Method to Measure the Instantaneous Temperature Rise in a Simulated Tissue Using Temperature-Sensitive Ink

2011 ◽  
Vol 2011 (0) ◽  
pp. 343-344
Author(s):  
Takashi Yoshii ◽  
Kosaku Kurata ◽  
Satoru Uchida ◽  
Takanobu Fukunaga ◽  
Hiroshi Takamatsu
Materials ◽  
2019 ◽  
Vol 12 (20) ◽  
pp. 3344 ◽  
Author(s):  
Zhiyuan Zhou ◽  
Massoud Sofi ◽  
Elisa Lumantarna ◽  
Rackel San Nicolas ◽  
Gideon Hadi Kusuma ◽  
...  

To address sustainability issues by facilitating the use of high-volume fly ash (HVFA) concrete in industry, this paper investigates the early age hydration properties of HVFA binders in concrete and the correlation between hydration properties and compressive strengths of the cement pastes. A new method of calculating the chemically bound water of HVFA binders was used and validated. Fly ash (FA) types used in this study were sourced from Indonesia and Australia for comparison. The water to binder (w/b) ratio was 0.4 and FA replacement levels were 40%, 50% and 60% by weight. Isothermal calorimetry tests were conducted to study the heat of hydration which was further converted to the adiabatic temperature rise. Thermo-gravimetric analysis (TGA) was employed to explore the chemically bound water (WB) of the binders. The results showed that Australian FA pastes had higher heat of hydration, adiabatic temperature rise, WB and compressive strength compared to Indonesian FA pastes. The new method of calculating chemically bound water can be successfully applied to HVFA binders. Linear correlation could be found between the WB and compressive strength.


2019 ◽  
Vol 19 (1) ◽  
pp. 26-47 ◽  
Author(s):  
Stefano Mariani ◽  
Sebastian Heinlein ◽  
Peter Cawley

Baseline subtraction is commonly used in guided wave structural health monitoring to identify the signal changes produced by defects. However, before subtracting the current signal from the baseline, it is essential to compensate for changes in environmental conditions such as temperature between the two readings. This is often done via the baseline stretch method that seeks to compensate for wave velocity changes with temperature. However, the phase of the signal generated by the transduction system is also commonly temperature sensitive and this effect is neglected in the usual compensation procedure. This article presents a new compensation procedure that deals with both velocity and phase changes. The results with this new method have been compared with those obtained using the standard baseline stretch technique on both a set of experimental signals and a series of synthetic signals with different coherent noise levels, feature reflections, and defect sizes, the range of noise levels and phase changes being chosen based on initial experiments and prior field experience. It has been shown that the new method both reduces the residual signal from a set baseline and enables better defect detection performance than the conventional baseline signal stretch method under all conditions examined, the improvement increasing with the size of the temperature and phase differences encountered. For example, in the experimental data, the new method roughly halved the residual between baseline and current signals when the two signals were acquired at temperatures 15°C apart.


2019 ◽  
Vol 11 (1) ◽  
pp. 168781401882073
Author(s):  
Lu-Chao Zhang ◽  
Li Zu

Based on the theory of thermal transmission, this article provides a new method to acquire the friction coefficient in ball screw mechanism. While the screw is in thermal equilibrium, the heat absorption is equal to the heat dissipation. The heat absorption is able to be achieved by calculating the heat energy due to the friction at the contact area and the heat dissipation can be calculated by the law of thermodynamics. When the temperature rise is determined, the heat dissipation can be obtained and the friction coefficient in ball screw mechanism can be calculated further. In order to confirm the validity of this method, a measuring system is constructed to obtain the temperature rise of ball screws. The experimental results show that the temperature rise has the same tendency with the theoretical values depending on this model. Therefore, it can be exploited to predict the temperature rise of ball screws in the rated life cycle when the ball screw is under the condition of thermal equilibrium. Furthermore, this model can be used to evaluate the mechanical efficiency, which is an important parameter for the performance of the ball screw.


1998 ◽  
Vol 42 (4) ◽  
pp. 889-894 ◽  
Author(s):  
Timothy R. Hammonds ◽  
Anthony Maxwell ◽  
John R. Jenkins

ABSTRACT Topoisomerase II catalyzes the passage of one DNA helix through another via a transient double-stranded break. The essential nature of this enzyme in cell proliferation and its mechanism of action make it an ideal target for cytotoxic agents. Saccharomyces cerevisiae topoisomerase II has been frequently used as a model for testing potential inhibitors of eukaryotic topoisomerase II as antitumor agents. The standard in vivo method of estimating the sensitivity of S. cerevisiae to the antitopoisomerase drugs is via inhibition or kill curves which rely on viable-cell counts and is labor intensive. We present an alternative to this, a high-throughput in vivo screen. This method makes use of a drug-permeable S. cerevisiae strain lacking endogenous topoisomerase II, which is modified to express either human topoisomerase IIα or IIβ or S. cerevisiae topoisomerase II carried on plasmids. Each modified strain expresses a full-length topoisomerase II enzyme, as opposed to the more commonly used temperature-sensitive S. cerevisiae mutant expressing yeast or yeast/human hybrid enzymes. A comparison of this new method with a plating-and-counting method gave similar drug sensitivity results, with increased accuracy and reduced manual input for the new method. The information generated has highlighted the sensitivities of different topoisomerase II enzymes and isoenzymes to several different classes of topoisomerase II inhibitor.


Author(s):  
Borut Cerne ◽  
Damijan Zorko ◽  
Joze Duhovnik ◽  
Joze Tavcar ◽  
Roman Zavbi

Abstract The presented work describes a computational method for carrying out a detailed and thorough examination of the flash temperature rise (i.e. the local ‘instantaneous’ temperature increase on a contact interface, due to frictional effects) present on the tooth flanks of a polymer gear pair, composed of a combination of POM and PA66 thermoplastics, during a given meshing cycle. The method involves a decoupled sequential procedure, where first the mechanical response of the gear teeth during a whole meshing cycle is analyzed using finite element analysis and, subsequently, a semi-analytical thermal analysis procedure is employed, with which the local flash temperature rise under a given tooth-pair contact can be evaluated. The method provides an accurate reproduction of the actual thermo-mechanical processes taking place at the gear teeth contact interfaces and allows for an investigation of the influence of deviations in the gear flank geometry and gear tolerances, while retaining a manageable enough form for application with moderate computational resources.


1978 ◽  
Vol 31 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Peter Sudbery ◽  
Kari Haugli ◽  
Finn Haugli

SUMMARYA new method for the isolation of temperature-sensitive mutants of Physarum polycephalum is described. It involves enrichment and prescreening of mutagenized amoebae followed by screening at both the plasmodial and amoebal stage. A total of 74 temperature-sensitive strains were recovered of which 26 were temperature-sensitive only as plasmodia, 35 only as amoebae and 13 in both stages. After a shift to the nonpermissive temperature, DNA and protein synthesis were followed in temperature-sensitive plasmodia to discover if the lesion affected functions of the nuclear cycle.


Genetics ◽  
1975 ◽  
Vol 79 (2) ◽  
pp. 175-186
Author(s):  
Susan A Henry ◽  
Bernard Horowitz

ABSTRACT A new method for the selection of auxotrophic, antibiotic- and temperature-sensitive mutants in Saccharomyces cerevisiae is reported. The technique is based upon the observation that certain fatty acid auxotrophs of yeast die when deprived of fatty acid only under conditions supporting growth. When macromolecular synthesis is blocked, the fatty acid-starved cells survive. By appropriate manipulation of a fatty acid-requiring strain enrichment as great as 75-fold was achieved for certain classes of auxotrophic mutants. An enrichment of approximately 100-fold is possible for some antibiotic-sensitive mutants. Selection for temperature-sensitive mutants, however, resulted in less than a 2-fold increase in the frequency of such mutants, probably because of the heterogeneity of this mutant category. It is likely that only that fraction of temperature-sensitive mutations which rapidly and reversibly blocks macromolecular synthesis is selected by this technique.


2012 ◽  
Vol 55 (23-24) ◽  
pp. 7207-7212 ◽  
Author(s):  
Kosaku Kurata ◽  
Takashi Yoshii ◽  
Satoru Uchida ◽  
Takanobu Fukunaga ◽  
Hiroshi Takamatsu

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