Review of the International Scientific and Practical Conference “Third Baskin Readings. Law and State of the Information Era: New Challenges and Prospects” (St. Petersburg, April 28, 2021)

In the review of the conference “The Third Baskin Readings. Law and State of the Information Era: New Challenges and Prospects” presents a summary of the main theses of the speakers on the problems of digitalization, the concept and protection of human rights and freedoms in a digital society, the role of artificial intelligence, transformation of law as such and other issues. The speakers generally concluded that there was no special change in the legal system for the needs of digitalization, concluded that law as a social phenomenon has a high degree of adaptability to changing conditions, and the use of new technologies should not affect the content of legal regulation as a whole. However, during the discussion, it is proposed to consider new signs of law, for example, “seriousness of law” in relation to the theory of the game. The participants come to the conclusion that the world is multipolar and at the same time there can be various structures of law and state, characteristic of different stages of socio-economic development of societies.

State Characteristic Clustering for Nonintrusive Load Monitoring with Stochastic Behaviours in Smart Grids

Integrating the nonintrusive load monitoring (NILM) technology into smart meters poses challenges in demand-side management (DSM) of the smart grid when capturing detailed power information and stochastic consumption behaviours, due to the difficulties in accurately detecting load operation states in real household environments with the limited information available. In this paper, a state characteristic clustering (SCC) approach is presented for promoting the performance of event detection in NILM, which makes full use of multidimensional characteristic information. After identifying different types of state domains in an established multidimensional characteristic space, we design a sliding window difference search method (SWDS) to extract their initial clustering centre. Meanwhile, the mean-shift updating and iterating procedures are conducted to find the potential terminal stable state according to the probability density function. The above control strategy considers the transient events and stable states in a time-series dataset simultaneously, which thus allows the exact state of complex events to be obtained in a fluctuating environment. Moreover, a multisegment computing scheme is applied for fast computing in the state characteristic clustering process. Experiments of three different cases on both our real household dataset and REDD public dataset are provided to reveal the higher performance of the proposed SCC approach over the existing related methods.

A Novel Deep Blue LE-Dominated HLCT Excited State Design Strategy and Material for OLED

Deep blue luminescent materials play a crucial role in the organic light-emitting diodes (OLEDs). In this work, a novel deep blue molecule based on hybridized local and charge-transfer (HLCT) excited state was reported with the emission wavelength of 423 nm. The OLED based on this material achieved high maximum external quantum efficiency (EQE) of 4% with good color purity. The results revealed that the locally-excited (LE)-dominated HLCT excited state had obvious advantages in short wavelength and narrow spectrum emission. What is more, the experimental and theoretical combination was used to describe the excited state characteristic and to understand photophysical property.

Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence

ABSTRACTCD8+ T cells are important antiviral effectors that can potentiate long-lived immunity against COVID-19, but a detailed characterization of these cells has been hampered by technical challenges. We screened 21 well-characterized, longitudinally-sampled convalescent donors that recovered from mild COVID-19 against a collection of SARS-CoV-2 tetramers, and identified one participant with an immunodominant response against Nuc322-331, a peptide that is conserved in all the SARS-CoV-2 variants-of-concern reported to date. We conducted 38- parameter CyTOF phenotyping on tetramer-identified Nuc322-331-specific CD8+ T cells, and on CD4+ and CD8+ T cells recognizing the entire nucleocapsid and spike proteins from SARS- CoV-2, and took 32 serological measurements on longitudinal specimens from this participant. We discovered a coordination of the Nuc322-331-specific CD8+ T response with both the CD4+ T cell and antibody pillars of adaptive immunity. Nuc322-331-specific CD8+ T cells were predominantly central memory T cells, but continually evolved over a ∼6-month period of convalescence. We observed a slow and progressive decrease in the activation state and polyfunctionality of the Nuc322-331-specific CD8+ T cells, accompanied by an increase in their lymph-node homing and homeostatic proliferation potential. These results suggest that following a typical case of mild COVID-19, SARS-CoV-2-specific CD8+ T cells not only persist but continuously differentiate in a coordinated fashion well into convalescence, into a state characteristic of long-lived, self-renewing memory.

Multiple and ectopic pregnancies, as well as anomalies in the development of female genital organs, are considered from the point of view of the doctrine of human origin

The teachings of Darwin and Haekel's, gave rise to the author's idea, whether some phenomena in the field of obstetrics, which are considered to be pathological, do not correspond only to a state characteristic of an earlier period of organic evolution.

A Novel Method to Evaluate the Effect of Slope Blasting under Impact Loading

In this paper, the quantitative evaluation of the explosion effect based on the fuzzy comprehensive evaluation method is proposed to describe the qualitative evaluation results. The selected state characteristic parameters are expressed by two kinds of membership functions, fuzzy normal and triangular distribution membership functions, and preliminary evaluation results are obtained. The validity index of the maximum membership principle is used to assess the accuracy of the evaluation results of two algorithms, and a relevant approaching degree is chosen to optimize the results. The entire evaluation process selects eleven indicators to form an evaluation set, including the boulder yield, root rate, flying distance of flyrock, explosive consumption, postcracking distance, detonator unit consumption, vibration velocity, loose coefficient, cast distance, throw rate, and blasted volume per meter of hole. Part of the indicator parameters are derived from field test monitoring, and another part of the indicator parameters are derived from numerical simulation. The simulation process uses the user-defined material interface function provided by LS-DYNA. And the numerical model of slope blasting is established by embedding the evolution relationship of tensile and compressive damage into the elastoplastic constitutive material. The evaluation method proposed in this paper is used to evaluate the postexplosion effect of Zijin Mountain gold-copper mine slope cast blasting. The results demonstrate that the fuzzy normal distribution membership function can correlate the state characteristic information and evaluation index effectively, and the working condition after explosion can be reflected accurately. Additionally, the influencing factors can be ranked by the importance degrees according to the calculated value of the evaluation index.

TOURISM LAW (STUDY ON THE DUTCH CEMETRY IN PENELEH SURABAYA)

A law is said to be good if the law goes according to its function. By all means is to implement the law in law science. The application of the law is a state characteristic of the law in which the application will be achieved legal objectives consisting of legal justice, legal certainty and legal benefit. Starting from this, the development of tourism in Indonesia, especially in the Dutch cemetry in Peneleh Surabaya does not comply with Act No. 10-2009. This development is also influenced by human resources in this case the government of Surabaya is less concerned about the existence of the Dutch cemetry in Peneleh Surabaya. By doing empirism Research, the results are still low desire of Surabaya city government because the location is not located in the city center