scholarly journals Bone mineral as a drug-seeking moiety and a waste dump

2020 ◽  
Vol 9 (10) ◽  
pp. 709-718
Author(s):  
Deepak Bushan Raina ◽  
Yang Liu ◽  
Otto L. P. Jacobson ◽  
K Elizabeth Tanner ◽  
Magnus Tägil ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Trace Elements ◽  
Human Health ◽  
Bone Mineral ◽  
Historical Perspective ◽  
Review Article ◽  
Waste Dump ◽  
Drug Seeking ◽  
Complex Process ◽  
Crystal Structure And Chemistry

Bone is a dynamic tissue with a quarter of the trabecular and a fifth of the cortical bone being replaced continuously each year in a complex process that continues throughout an individual’s lifetime. Bone has an important role in homeostasis of minerals with non-stoichiometric hydroxyapatite bone mineral forming the inorganic phase of bone. Due to its crystal structure and chemistry, hydroxyapatite (HA) and related apatites have a remarkable ability to bind molecules. This review article describes the accretion of trace elements in bone mineral giving a historical perspective. Implanted HA particles of synthetic origin have proved to be an efficient recruiting moiety for systemically circulating drugs which can locally biomodulate the material and lead to a therapeutic effect. Bone mineral and apatite however also act as a waste dump for trace elements and drugs, which significantly affects the environment and human health. Cite this article: Bone Joint Res 2020;9(10):709–718.

CO-OCCURRING TRACE ELEMENTS (CTES) OF POTENTIAL HUMAN HEALTH CONCERN IN ARSENIC CONTAMINATED AQUIFERS IN THE BENGAL BASIN

2020 ◽  
Author(s):  
Harshad Vijay Kulkarni ◽  
◽  
Michael Vega ◽  
Karen Johannesson ◽  
Robert Taylor ◽  
...  
Keyword(s):  
Trace Elements ◽  
Human Health ◽  
Health Concern ◽  
Bengal Basin ◽  
Contaminated Aquifers ◽  
Potential Human Health

scholarly journals Modulation of Gut Microbiota for the Prevention and Treatment of COVID-19

2021 ◽  
Vol 10 (13) ◽  
pp. 2903
Author(s):  
Jiezhong Chen ◽  
Luis Vitetta
Keyword(s):  
Clinical Trials ◽  
Trace Elements ◽  
Gut Microbiota ◽  
Human Health ◽  
Intestinal Microbiota ◽  
Narrative Review ◽  
Bacterial Metabolites ◽  
Gut Dysbiosis ◽  
Prevention And Treatment

The gut microbiota is well known to exert multiple benefits on human health including protection from disease causing pathobiont microbes. It has been recognized that healthy intestinal microbiota is of great importance in the pathogenesis of COVID-19. Gut dysbiosis caused by various reasons is associated with severe COVID-19. Therefore, the modulation of gut microbiota and supplementation of commensal bacterial metabolites could reduce the severity of COVID-19. Many approaches have been studied to improve gut microbiota in COVID-19 including probiotics, bacterial metabolites, and prebiotics, as well as nutraceuticals and trace elements. So far, 19 clinical trials for testing the efficacy of probiotics and synbiotics in COVID-19 prevention and treatment are ongoing. In this narrative review, we summarize the effects of various approaches on the prevention and treatment of COVID-19 and discuss associated mechanisms.

scholarly journals Occurrence of trace elements (TEs) in seafood from the North Persian Gulf: Implications for human health

2021 ◽  
Vol 97 ◽  
pp. 103754
Author(s):  
Naghmeh Soltani ◽  
Michel Marengo ◽  
Behnam Keshavarzi ◽  
Farid Moore ◽  
Peter S. Hooda ◽  
...  
Keyword(s):  
Trace Elements ◽  
Human Health ◽  
Persian Gulf ◽  
The North

Trace elements and human health

2005 ◽  
Vol 26 (4-5) ◽  
pp. 233-234 ◽  
Author(s):  
Cesar G. Fraga ◽  
Patricia I. Oteiza ◽  
Carl L. Keen
Keyword(s):  
Trace Elements ◽  
Human Health

PULP STONES: A REVIEW

2021 ◽  
pp. 48-50
Author(s):  
Eva Shukla ◽  
Shruthi Nagaraja
Keyword(s):  
Historical Perspective ◽  
Review Article ◽  
Young Population ◽  
Etiological Factors ◽  
Dependent Process ◽  
Age Dependent ◽  
Pulp Stones

Pulp stones are seen to be a fairly common nding in most routine radiographs but they have been given relatively less attention in research as well as textbooks. New investigations have been done in abundance when it comes to their prevalence as well as etiological factors. Despite numerous studies, their formation still remains a riddle for endodontists and researchers alike. Historical perspective of pulp stones being an age dependent process are now being questioned as more studies report their prevalence in young population. This review article evaluates the recent studies pertaining to pulpal calcications where newer etiological factors as well as molecular factors have been highlighted in their formation. Their signicance has been largely studied correlating their occurrence with various other systemic calcications.

Review article: Placental handling of trace elements

Placenta ◽  
1988 ◽  
Vol 9 (3) ◽  
pp. 333-343 ◽  
Author(s):  
D.B. Shennan ◽  
C.A.R. Boyd
Keyword(s):  
Trace Elements ◽  
Review Article

Assessing the potential origins and human health risks of trace elements in groundwater: A case study in the Khoy plain, Iran

2018 ◽  
Vol 41 (2) ◽  
pp. 981-1002 ◽  
Author(s):  
Rahim Barzegar ◽  
Asghar Asghari Moghaddam ◽  
Jan Adamowski ◽  
Amir Hossein Nazemi
Keyword(s):  
Trace Elements ◽  
Human Health ◽  
Health Risks ◽  
Human Health Risks

scholarly journals Comparison of the Mineral and Nutraceutical Profiles of Elephant Garlic (Allium ampeloprasum L.) Grown in Organic and Conventional Fields of Valdichiana, a Traditional Cultivation Area of Tuscany, Italy

Biology ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1058
Author(s):  
Stefano Loppi ◽  
Riccardo Fedeli ◽  
Giulia Canali ◽  
Massimo Guarnieri ◽  
Stefano Biagiotti ◽  
...  
Keyword(s):  
Trace Elements ◽  
Rare Earth ◽  
Rare Earth Elements ◽  
Water Content ◽  
Human Health ◽  
Soluble Sugars ◽  
Allium Ampeloprasum ◽  
Icp Ms ◽  
Essential Trace Elements ◽  
Reference Plant

In the Valdichiana area (Tuscany, Italy) an ancient native landrace of elephant garlic (Allium ampeloprasum L.), locally known as “Aglione della Valdichiana”, has long been cultivated. The aim of this study was to check whether there are differences in the mineral and nutraceutical profiles of the Aglione della Valdichiana cultivated conventionally and organically. Based on the analysis by ICP-MS of a wide array of major, minor, essential, and non-essential trace elements as well as rare earth elements, and the evaluation of the content of polyphenols, flavonoids, antioxidants, soluble proteins, soluble sugars, and starch, as well as the weight and water content, it was concluded that differences in the mineral and nutraceutical profiles of organically and conventionally grown bulbs were very limited. Only a statistically (p < 0.05) higher concentration of Cd (+2620%), Co (+113%), Mn (+55%), Rb (+180%), and Sb (+180%), as well as glucose (+37%) in conventionally cultivated bulbs emerged. Cadmium was the only element slightly higher than in the “reference plant,” but with a negligible risk (three orders of magnitude lower) for human health based on consumption. It is concluded that we failed to find evidence of healthier food or a higher nutraceutical quality for organically cultivated elephant garlic.

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