scholarly journals Musculoskeletal Tuberculosis in Bradford – A 6-Year Review

2007 ◽  
Vol 89 (4) ◽  
pp. 405-409 ◽  
Author(s):  
JC Talbot ◽  
Q Bismil ◽  
D Saralaya ◽  
DAG Newton ◽  
RM Frizzel ◽  
...  

INTRODUCTION Tuberculosis (TB) remains the most common cause of death from infectious disease world-wide. In the UK, the incidence of TB has risen by 25% over the last 10 years; extrapulmonary diagnosis remains challenging and can be delayed. This study evaluates the epidemiology of musculoskeletal tuberculosis in a large multi-ethnic UK city. PATIENTS AND METHODS A review of prospectively recorded data of incidence, anatomical site, ethnic distribution, treatment and drug resistance of musculoskeletal tuberculosis over a 6-year period was performed. RESULTS From January 1999 to December 2004, there were 729 TB notifications; 61 cases (8.4%) had musculoskeletal involvement. Of the patients, 74% were immigrants from the Indian subcontinent; nearly 50% had spinal involvement; 24 patients underwent surgical intervention; 29 were subjected to either diagnostic or therapeutic radiological intervention; and resolution of symptoms was achieved in 59 out of 61 cases. CONCLUSIONS This study highlights the high proportion of musculoskeletal TB in immigrant patients in an area with a relatively large at-risk population, but will also serve to alert physicians, in areas with smaller at-risk populations, of the possibility of musculoskeletal TB.

2018 ◽  
Vol 104 (3) ◽  
pp. 120-123
Author(s):  
Sebastian J Gray ◽  
Katrina Cathie

Varicella zoster virus primarily causes chickenpox, usually a mild self-limiting illness of childhood. However, complications occur in 1% with 4200 annual deaths. Since the first vaccination was developed in the 1970s, many countries have introduced universal mass immunisation, but the UK currently only routinely immunises ‘at-risk’ populations. With increasing availability of private varicella vaccination, this article reviews the pros and cons of whether parents should be immunising their children with the chickenpox vaccine privately.


2020 ◽  
Author(s):  
Areen Omary

Aims: This study aims to examine if age and marital status can predict the risk for binge alcohol use (BAU) among adults with a major depressive episode (MDE). Methods: Data from the Substance Abuse and Mental Health Services Administration’s (SAMHSA) 2018 National Survey for Drug Use and Health (NSDUH) were analyzed. The unweighted sample included 6,999 adults representing a weighted population size of 33,900,452.122 in the US. Results and Conclusions: The findings of this retrospective research confirmed that age and marital status significantly predicted BAU in the past month among adults with MDE. Adults with MDE at higher risk for BAU were adults under the age of 50, adults who were never married, and adults who were divorced/separated. Special attention must be paid to those in age groups under 50, never married, and have been separated/divorced who are particularly at-risk for future alcohol abuse. Future research should consider examining additional potential confounders for BAU among other at-risk populations.


2020 ◽  
Vol 222 (4) ◽  
pp. S886.e1-S886.e9 ◽  
Author(s):  
Abigail Liberty ◽  
Kimberly Yee ◽  
Blair G. Darney ◽  
Ana Lopez-Defede ◽  
Maria I. Rodriguez

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Aker ◽  
A Askari ◽  
M Rabie ◽  
M Aly ◽  
S Adegbola ◽  
...  

Abstract Introduction Colorectal anastomotic leaks (AL) are an unfortunate occurrence and are associated with a high mortality. The aim of this multi-centre study is to explore the different management strategies used and compare outcomes in the management of AL. Method All patients who had an AL were included at seven hospitals across the East of England. Morbidity, mortality, and survival were compared across the different management strategies. Results A total of 247 consecutive patients were included of which 60.3% were male and the median age was 68 (IQR 57-77). Half of patients were initially managed conservatively, a further 10.5% had a radiological procedure. 39.7% required surgery as an initial treatment. Of those who initially did not have a surgical intervention (n = 149), 10.7% (n = 16/149) eventually required laparotomy. Ultimately, 42.7% (n = 106/248) required a laparotomy. The 30- and 90-day across the entire population mortality were 3.6% and 4.9% respectively. There were no significant differences in mortality or long-terms survival between the different initial treatment modalities. Conclusions Despite initial conservative, antibiotic and radiological intervention being successful in the majority of patients, two out of five patients will still require a laparotomy. A consensus approach is required to standardise management in these difficult scenarios.


2020 ◽  
pp. 095646242094756
Author(s):  
Sabina O Nduaguba ◽  
Kentya H Ford ◽  
James P Wilson ◽  
Kenneth A Lawson ◽  
Robert L Cook

We aimed to identify subgroups within age, racial/ethnic, and transmission categories that drive increased risk for late HIV diagnosis (LHD). A 1996–2013 retrospective study of HIV-diagnosed individuals (N = 77,844) was conducted. The proportion of individuals with LHD (AIDS diagnosis within 365 days of HIV diagnosis) was determined, stratified by age, race/ethnicity, and transmission category. Logistic regression with interaction terms was used to identify groups/subgroups at risk for LHD during 1996–2001, 2002–2007, and 2008–2013. Respectively, 78%, 27%, 38%, and 31% were male, White, Black, and Hispanic. Overall, 39% had LHD with a 6.7% reduction for each year increase (OR = 0.93, 95% CI = 0.93–0.94, p < 0.01). Older age was significantly associated with increased odds of LHD (OR range = 1.90–4.55). Compared to their White counterparts, all Hispanic transmission categories (OR range = 1.31–2.58) and only Black female heterosexuals and men who have sex with men (MSM) (OR range = 1.14–1.33) had significantly higher odds of LHD during 1996–2001 and/or 2002–2007. Significance was limited to Hispanic MSM (all age categories), MSM/IDUs (30–59 years), and heterosexuals (18–29 years) and Black MSM (30–39 years) during 2008–2013. Older individuals and Hispanics (driven by MSM) are at increased risk for LHD. HIV testing interventions directed at seniors and Hispanic MSM can further reduce rates of LHD.


PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e80594 ◽  
Author(s):  
Huanmiao Xun ◽  
Dianmin Kang ◽  
Tao Huang ◽  
Yuesheng Qian ◽  
Xiufang Li ◽  
...  

2011 ◽  
Vol 57 ◽  
pp. S96-S99 ◽  
Author(s):  
Chris Beyrer ◽  
Stefan Baral ◽  
Deanna Kerrigan ◽  
Nabila El-Bassel ◽  
Linda-Gail Bekker ◽  
...  

Sociology ◽  
2016 ◽  
Vol 51 (2) ◽  
pp. 323-338 ◽  
Author(s):  
Bridget Byrne

Citizenship tests are designed to ensure that new citizens have the knowledge required for successful ‘integration’. This article explores what those who have taken the test thought about its content. It argues that new citizens had high levels of awareness of debates about immigration and anti-immigration sentiment. Considering new citizens’ views of the test, the article shows how many of them are aware of the role of the test in reassuring existing citizens of their fitness to be citizens. However, some new citizens contest this positioning in ‘acts of citizenship’ where they assert claims to citizenship which are not necessarily those constructed by the state and implied in the tests. The article will argue that the tests and the nature of the knowledge required to pass them serve to retain new citizens in a position of less-than-equal citizenship which is at risk of being discursively (if less often legally) revoked.


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