Dental stem cells and bone repair
Repair of a periodontal bone defect following surgery or trauma is essential to prevent further bone loss through resorption (Figure 1). Materials currently used for this procedure include autologous bone, deproteinised bovine bone or alloplastic bone substitutes. Although effective at maintaining periodontal architecture, these graft materials can be difficult to implant and may fail to incorporate into host tissue. Dental stem cells are currently being investigated for repair of mandibular bone defects. Recent clinical pilot studies in which autologous dental stem cells have been grafted into mandibular defects have produced encouraging results. This review will discuss current research surrounding the development of dental stem cells for bone augmentation and repair.