Drug—Drug Interactions in the Elderly

2002 ◽  
Vol 36 (11) ◽  
pp. 1675-1681 ◽  
Author(s):  
Ingeborg K Björkman ◽  
Johan Fastbom ◽  
Ingrid K Schmidt ◽  
Cecilia B Bernsten ◽  
Cecilia B Bernsten ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Elderly People ◽  
The Elderly ◽  
Drug Regimen ◽  
European Countries ◽  
Elderly Persons ◽  
Potential Ddis ◽  
Negative Effects ◽  
Outpatient Group ◽  
The Impact

OBJECTIVE: To detect the frequency of potential drug—drug interactions (DDIs) in an outpatient group of elderly people in 6 European countries, as well as to describe differences among countries. DATA SOURCES AND METHODS: Drug use data were collected from 1601 elderly persons living in 6 European countries. The study population participated in a controlled intervention study over 18 months investigating the impact of pharmaceutical care. Potential DDIs were studied using a computerized detection program. RESULTS: The elderly population used on average 7.0 drugs per person; 46% had at least 1 drug combination possibly leading to a DDI. On average, there were 0.83 potential DDIs per person. Almost 10% of the potential DDIs were classified to be avoided according to the Swedish interaction classification system, but nearly one-third of them were to be avoided only for predisposed patients. The risk of subtherapeutic effect as a result of a potential DDI was as common as the risk of adverse reactions. Furthermore, we found differences in the frequency and type of potential DDIs among the countries. CONCLUSIONS: Potential DDIs are common in elderly people using many drugs and are part of a normal drug regimen. Some combinations are likely to have negative effects; more attention must be focused on detecting and monitoring patients using such combinations. As differences in potential DDIs among countries were found, the reasons for this variability need to be explored in further studies.

scholarly journals The Enabling Role of ICT to Mitigate the Negative Effects of Emotional and Social Loneliness of the Elderly during COVID-19 Pandemic

2021 ◽  
Vol 18 (8) ◽  
pp. 3923
Author(s):  
Carmen Llorente-Barroso ◽  
Olga Kolotouchkina ◽  
Luis Mañas-Viniegra
Keyword(s):  
Elderly People ◽  
Social Isolation ◽  
Well Being ◽  
The Elderly ◽  
Physical Contact ◽  
Emotional Impact ◽  
Negative Effects ◽  
Information And Communication ◽  
Qualitative Exploration ◽  
The Impact

(1) Background: The COVID-19 pandemic has been especially hard on the elderly owing to their particular vulnerability to the virus. Their confinement to prevent the spread of the virus resulted in social isolation, often linked to the unwanted loneliness that hinders their emotional well-being. The enabling capacity of ICT (Information and Communication Technology) to overcome the negative effects of this isolation requires special attention. The purpose of this research is to understand the impact of the use of ICT on the emotional well-being of elderly people during their confinement. (2) Methods: A qualitative exploration method based on four focus groups with elderly people aged 60 years or older and three in-depth personal interviews with experts in education of the elderly were carried out. (3) Results: Research results evidence a negative emotional impact of the confinement (lack of physical contact with their loved ones, fear and uncertainty, feeling of loneliness, sadness at the loss of family members) on the emotional well-being of study participants. Furthermore, the operational capacity of ICT to prevent infection, as well as their positive emotional and humanizing role in providing access to entertainment and hobbies, and in improving self-esteem was also acknowledged. (4) Conclusions: ICT have become a valuable ally for elderly people aged 60 years and older to mitigate the negative effects of social isolation and loneliness imposed by the confinement.

Study on medication prescription in the elderly population: benzodiazepine use and potential drug interactions

2021 ◽  
Author(s):  
Mariana Macedo Alvim ◽  
Danielle Teles da Cruz ◽  
Glenda de Almeida Aquino ◽  
Isabel Cristina Gonçalves Leite
Keyword(s):  
Drug Interactions ◽  
Elderly People ◽  
Elderly Population ◽  
Inappropriate Medication ◽  
The Elderly ◽  
Community Dwelling ◽  
Elderly Persons ◽  
Potential Drug ◽  
Elderly Individuals ◽  
Benzodiazepine Use

Abstract Background Prescription of medications for elderly individuals is complex, potentially involving polypharmacy, drug interactions, and inappropriate medication. Notable among the medications are benzodiazepines, whose long-term use is common and growing among the elderly population. Objective This study aimed to evaluate the occurrence of potential drug interactions (PDI) in elderly community-dwelling patients who use benzodiazepines. Method Cross-sectional study, conducted via household survey, with 73 elderly persons in Juiz de Fora, MG, Brazil. The search and classification of PDIs was carried out using the Micromedex® system. Results The prevalence of benzodiazepine use in this population was 18.3% (95% CI, 15.2-21.6). The use of benzodiazepines was associated with polypharmacy (p<0.01; PR 3.03; 95% CI, 1.79-5.26). A total of 157 PDI occurrences were found in 69.9% of the elderly people assessed. Of these, 25 were related to benzodiazepines. In the elderly individuals who use benzodiazepines, polypharmacy was associated with PDI (p<0.01; PR = 16.13; 95% CI, 4.67-55.55). PDI occurrence was high in the elderly people who use benzodiazepines, including interactions of highly significant clinical value. Conclusion In general, PDI is associated with polypharmacy, which demonstrates the need to rationalize drug use in the elderly population through continuous monitoring, seeking the simplest and safest possible therapeutic regimen.

Forms of physical activity of the elderly

2020 ◽  
Vol 18 (3) ◽  
pp. 221-228
Author(s):  
Piotr Czarnecki ◽  
◽  
Justyna Podgórska-Bednarz ◽  
Lidia Perenc ◽  
◽  
...  
Keyword(s):  
Physical Activity ◽  
Elderly People ◽  
Population Aging ◽  
Human Life ◽  
Good Health ◽  
The Elderly ◽  
Polish Society ◽  
Central Statistical ◽  
Key Phrases ◽  
The Impact

Introduction. Physical activity is known to be an important factor influencing health throughout human life. This issue has become crucial for public health due to the aging of the population in both developed and developing countries. Aim. is to present a literature review on the forms of physical activity undertaken by the elderly, as well as on issues related to physical activity and the population aging. Material and methods. The study was prepared on the basis of a review of Polish and foreign literature. The following databases and data sources were used: EBSCO, ScienceDirect and Google Scholar. An additional source of data were the websites of the Central Statistical Office. Strictly defined key phrases were used during the collection of literature. The work has been divided into thematic subsections on the aging of the society, the impact of physical activity on health and the main topic, i.e. forms of physical activity selected by the elderly. Analysis of the literature. The number of elderly people in Polish society has increased by almost 3.7 million over three decades. Therefore, an important topic is prophylaxis aimed at increasing the number of days in good health, largely covering the broadly understood activation of the elderly. The available data indicate that only 12% of elderly people undertake physical activity once a week. The most common form of spending free time actively is walking (as many as 73% of people in this population declare this form of physical activity in one of the presented studies). Conclusion. Organized forms of physical activity are undertaken much less frequently by the analyzed age group mainly due to financial limitations and limited availability of sports infrastructure.

scholarly journals Differences between the Sexes in the Relationship between Chronic Pain, Fatigue, and QuickDASH among Community-Dwelling Elderly People in Japan

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 630
Author(s):  
Satoshi Shimo ◽  
Yuta Sakamoto ◽  
Takashi Amari ◽  
Masaaki Chino ◽  
Rie Sakamoto ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Elderly People ◽  
Physical Disability ◽  
The Elderly ◽  
Daily Basis ◽  
Community Dwelling ◽  
Negative Effects ◽  
The Relationship ◽  
Elderly Healthcare ◽  
Disability Research

Chronic pain and fatigue have negative effects on the health, ADL, work, and hobbies of the elderly. As the proportion of people 65 years of age and older in the population increases, chronic pain and disability research regarding this group is receiving more consideration. However, little empirical evidence of the association between chronic pain, fatigue, and physical disability between the sexes is available. This study investigated the association between chronic pain, fatigue, and instrumental activities of daily living among community-dwelling elderly people by sex in Japan. Concerning the presence of chronic pain, 61% of males and 78% of females reported chronic pain, indicating that many elderly people living in the community suffer from chronic pain and fatigue on a daily basis. The number of sites of chronic pain was higher in females than in males (p = 0.016), with more chronic pain in the knees (p < 0.001) and upper arms (p = 0.014). Regarding chronic pain, males showed a higher correlation with QuickDASH-DS (rs = 0.433, p = 0.017) and QuickDASH-SM (rs = 0.643, p = 0.018) than females. Furthermore, fatigue also showed a higher correlation with QuickDASH-W (rs = 0.531, p = 0.003) in males than in females. These results indicate that the association between chronic pain, fatigue, and QuickDASH differed between the sexes among community-dwelling elderly people in Japan. A better understanding of the risk factors for elderly chronic pain and fatigue among sexes will facilitate the development of elderly healthcare welfare and policies.

scholarly journals The impact of chronic disease and disability on the elderly

1999 ◽  
Vol 55 (3) ◽  
pp. 9-14
Author(s):  
C. J. Eales
Keyword(s):  
Health Care ◽  
Chronic Disease ◽  
Chronic Diseases ◽  
Health Care Systems ◽  
The Elderly ◽  
Therapeutic Interventions ◽  
Elderly Persons ◽  
Care Systems ◽  
And Function ◽  
The Impact

Health care systems for elderly people should aim to delay the onset of illness, reducing the final period of infirmity and illness to the shortest possible time. The most effective way to achieve this is by health education and preventative medicine to maintain mobility and function. Changes in life style even in late life may result in improved health, effectively decreasing the incidence of chronic diseases associated with advancing age. This paper presents the problems experienced by elderly persons with chronic diseases and disabilities with indications for meaningful therapeutic interventions.

Mourning and Reminiscence: Parallel Psychotherapeutic Processes for Elderly People

1989 ◽  
Vol 28 (4) ◽  
pp. 239-249 ◽  
Author(s):  
Linda L. Viney ◽  
Yvonne N. Benjamin ◽  
Carol Preston
Keyword(s):  
Elderly People ◽  
The Elderly ◽  
Relevant Information ◽  
Theoretical Explanation ◽  
Personal Construct ◽  
Elderly Persons ◽  
Personal Construct Theory ◽  
Psychotherapeutic Processes ◽  
Construct Theory ◽  
The Relationship

Mourning and reminiscence are therapeutic processes common in therapeutic work with the elderly. However, a theoretical explanation of why they are effective has been lacking. Personal construct theory accounts for both in terms of the search of elderly persons for validation of their construct systems. In this article, this explanation of the parallel psychotherapeutic processes is explored, together with relevant information from the literature on mourning and reminiscence. Therapeutic case studies illustrate the characteristics of the two processes and the relationship between them.

Does an impaired capacity for self-care impact the prevalence of social and emotional loneliness among elderly people?

2018 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Irena Canjuga ◽  
Danica Železnik ◽  
Marijana Neuberg ◽  
Marija Božicevic ◽  
Tina Cikac
Keyword(s):  
Health Care ◽  
Elderly People ◽  
Age Distribution ◽  
Self Care ◽  
The Elderly ◽  
The Self ◽  
Content Type ◽  
Care Assessment ◽  
Significant Difference ◽  
The Impact

Purpose The purpose of this paper is to explore the impact of self-care on the prevalence of loneliness among elderly people living in retirement homes and older people living in their homes/communities. Design/methodology/approach The research was conducted through standardized SELSA-L assessment loneliness questionnaires and the Self Care Assessment Worksheet for self-care assessment. The results were processed using the Kruskal–Wallis test. Findings The obtained results have shown that impaired self-care ability affects the prevalence of loneliness among the elderly almost the same in both groups of participants. However, regarding the relationship between the state of health and self-care, only a statistically significant difference in the prevalence of loneliness is found in the case of the participants living in their homes, with the worst health condition affecting the poorer psychological care. Research limitations/implications It is necessary to point out the limitations of the research, primarily sample limitations and the selected design of the study. The sample consisted of two different and relatively small groups of participants which could adversely affect the representativeness of the sample and reduce the possibility of generalising the results. The next limiting factor is the age distribution the authors used in the research, where the age of the participants as a very important variable was collected by age range and not precisely which consequently resulted in inequality in subgroup sizes. Thus, the middle age (75–85) covers up to ten years, which is a huge range at an older age and can mean major differences in functional ability, and can impact the self-care assessment. Practical implications Nurses are indispensable in care for the elderly and they need to promote and encourage self-care of the elderly through health care. Elderly people living in retirement homes should be allowed to participate equally in health care in order to preserve their own autonomy and dignity. However, to benefit those who live in their homes, nurses should be connected to the local community and thus stimulate various forms of preventative (testing blood sugar levels, blood pressure and educating on the importance of preventive examinations) or recreational activities in the environment of elderly people with the goal of preserving their functional abilities. Originality/value The impact of self-care on loneliness was not sufficiently researched, and this paper contributed to understanding the complexity of loneliness phenomena among the elderly with the aim of developing a model of prevention.

scholarly journals Analysis of potential drug interactions and adverse reactions to nonsteroidal anti-inflammatory drugs among the elderly

2016 ◽  
Vol 19 (3) ◽  
pp. 533-544 ◽  
Author(s):  
Tiago Aparecido Maschio de Lima ◽  
Adriana Antônia da Cruz Furini ◽  
Tábata Salum Calille Atique ◽  
Patricia Di Done ◽  
Ricardo Luiz Dantas Machado ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Prescription Drugs ◽  
Adverse Reactions ◽  
Drug Distribution ◽  
The Elderly ◽  
Elderly Persons ◽  
Potential Drug ◽  
Increased Risk ◽  
Chi Squared ◽  
Elderly Users

Abstract Objective: The aim of the present study was to analyze potential drug interactions and adverse reactions to NSAIDs in elderly users of a private drug distribution service. Method: A prospective, exploratory and descriptive study with a quantitative approach was performed. The elderly users of NSAIDs attended by the service were interviewed and their prescriptions analyzed between May and September, 2014. Analysis of drug interactions was performed through computerized databases. The post-sales analysis of adverse reactions was performed using the Adverse Drug Reaction Probability Scale. Statistical analysis was performed with the Chi-squared and Fisher's Exact tests. Results: The study evaluated 200 elderly persons, among whom women predominated (56.5%). The average age was 65 years ±10. The NSAIDs accounted for 38.7% of prescription drugs used, and included dipyrone (26.9%), nimesulide (22.8%) and ketoprofen (16.3%). A total of 8.5% of such drugs were considered inappropriate medications for the elderly. A total of 104 potential drug interactions were identified, of which 24% were considered highly clinically significant. The NSAIDs with the greatest risk of interactions were ketoprofen 46.2%, ketorolac 14.4%, nimesulide 12.5% and diclofenac 9.6%. In post-sales monitoring 30.5% of the elderly persons reported undesirable symptoms after the use of NSAIDs, with stomach discomfort the most prevalent (17%). Conclusion: The present study confirmed the importance of monitoring the use of NSAIDs among the elderly due to the increased risk of drug interactions and adverse reactions associated with age, concomitant diseases, multi- prescriptions and polypharmacy. The choice of appropriate drugs for the elderly, the reconciliation of all the medications taken by the patient, and effective pharmaceutical care are measures that can contribute to the rational and safe use of NSAIDs.

scholarly journals Scientific production on housing for autonomous elderly persons: an integrative literature review

2017 ◽  
Vol 20 (5) ◽  
pp. 713-721 ◽  
Author(s):  
Roberta de Miranda Henriques Freire ◽  
Nivaldo Carneiro Junior
Keyword(s):  
Quality Of Life ◽  
Public Housing ◽  
Elderly People ◽  
The Elderly ◽  
Scientific Production ◽  
Elderly Persons ◽  
Housing Policies ◽  
Analysis Technique ◽  
Housing For The Elderly

Abstract Objective: To analyze Brazilian scientific production on housing for autonomous elderly persons. Method: A descriptive, analytical integrative review type study was carried out. The following guiding question was defined: what is the Brazilian scientific production relating to housing for autonomous elderly persons in indexed on-line periodicals from 2000 to 2015? Results: Thirty-three articles were identified in total, of which only 13 met the inclusion criterion. Using the Content Analysis technique, the following categories were formed: Modalities of housing for the elderly; Public housing policies for the elderly and Housing and quality of life. Conclusion: Most of the studies discussed types of housing for the elderly, falling into the category "Modalities of housing for the elderly", and identifying a tendency towards one-person dwellings. In relation to the category "Public housing policies for the elderly", the articles reflected on the rights and the guarantees of the elderly in relation to a suitable home. The "Housing and quality of life" category aimed to compare the quality of life of elderly people living alone or with a partner, as well as their perception of exclusive condominium developments for this population. There is a need for research on the issue in question, since there is an increase in the number of elderly people without housing, making it necessary for the state to meet this demand.

Social Dimensions of Mental Illness among Rural Elderly Populations

1988 ◽  
Vol 26 (3) ◽  
pp. 169-190 ◽  
Author(s):  
Jon Hendricks ◽  
Howard B. Turner
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Physical Health ◽  
Elderly People ◽  
The Elderly ◽  
Rural Elderly ◽  
Policy Implications ◽  
Elderly Persons ◽  
Increased Risk ◽  
Elderly Populations

Despite growing concern with rural elderly populations, little attention has focused on their mental health, ways it may correlate with physical health, or how rural mental health patterns compare to urban. Popular wisdom contends that elderly people in general, and rural elderly persons in particular, are at increased risk for mental illness. This article examines these questions. A review of available literature suggests that elderly people may be at only slightly greater risk of mental illness than the population at large, though there are some indications that rates of depression may be somewhat higher among the elderly population. Much of this same literature implies that objective environmental conditions play a significant role in the incidence of depression. Analysis of data gathered in a statewide random poll ( N = 743) indicates that while physical health tends to be poorer among rural populations, when health is held constant there is actually an inverse relationship between age and depression. Therefore, rural elderly persons are no more likely to be depressed than their urban counterparts despite harsher living conditions. Both conceptual and policy implications are discussed.

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