Flow-Through Fourier Transform Infrared Sensor for Total Hydrocarbons Determination in Water

2009 ◽  
Vol 63 (9) ◽  
pp. 1015-1021 ◽  
Author(s):  
David Pérez-Palacios ◽  
Sergio Armenta ◽  
Bernhard Lendl
Keyword(s):  
Fourier Transform ◽  
Limit Of Detection ◽  
Solid Phase ◽  
Chlorinated Solvents ◽  
Analytical Signal ◽  
Fourier Transform Infrared ◽  
Minimal Sample ◽  
Relative Standard ◽  
Ft Ir ◽  
Flow Through

A new flow-through Fourier transform infrared (FT-IR) sensor for oil in water analysis based on solid-phase spectroscopy on octadecyl (C18) silica particles has been developed. The C18 non-polar sorbent is placed inside the sensor and is able to retain hydrocarbons from water samples. The system does not require the use of chlorinated solvents, reducing the environmental impact, and the minimal sample handling stages serve to ensure sample integrity whilst reducing exposure of the analyst to any toxic hydrocarbons present within the samples. Fourier transform infrared (FT-IR) spectra were recorded by co-adding 32 scans at a resolution of 4 cm−1 and the band located at 1462 cm−1 due to the CH2 bending was integrated from 1475 to 1450 cm−1 using a baseline correction established between 1485 and 1440 cm−1 using the areas as analytical signal. The technique, which provides a limit of detection (LOD) of 22 mg L−1 and a precision expressed as relative standard deviation (RSD) lower than 5%, is considerably rapid and allows for a high level of automation.

scholarly journals Development and Validation of a Simple Method to Quantify Contents of Phospholipids in Krill Oil by Fourier-Transform Infrared Spectroscopy

Foods ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 41
Author(s):  
Se-Eun Park ◽  
Hyo-Yeon Yu ◽  
Sangdoo Ahn
Keyword(s):  
Fourier Transform ◽  
31P Nmr ◽  
Limit Of Detection ◽  
Fourier Transform Infrared ◽  
Raw Material ◽  
Krill Oil ◽  
Simple Method ◽  
Nmr Method ◽  
Relative Standard ◽  
Ft Ir

This study focuses on developing a quantification method for phosphatidylcholine (PC) and total phospholipid (PL) in krill oil using Fourier-transform infrared (FT-IR) spectroscopy. Signals derived from the choline and phosphate groups were selected as indicator variables for determining PC and total PL content; calibration curves with a correlation coefficient of >0.988 were constructed with calibration samples prepared by mixing krill oil raw material and fish oil in different ratios. The limit of detection (LOD, 0.35–3.29%) of the method was suitable for the designed assay with good accuracy (97.90–100.33%). The relative standard deviations for repeatability (0.90–2.31%) were acceptable. Therefore, both the methods using absorbance and that using second-derivative were confirmed to be suitable for quantitative analysis. When applying this method to test samples, including supplements, the PC content and total PL content were in good agreement with an average difference of 2–3% compared to the 31P NMR method. These results confirmed that the FT-IR method can be used as a convenient and rapid alternative to the 31P NMR method for quantifying PLs in krill oil.

scholarly journals Application of Fourier Transform Infrared Spectrophotometry Method for Analysis of Metformin Hydrochloride in Marketed Tablet Dosage Form

2021 ◽  
Vol 7 (2) ◽  
pp. 168-177
Author(s):  
Nerdy Nerdy ◽  
Linda Margata ◽  
Dian Ika Perbina Meliala ◽  
Bunga Mari Sembiring ◽  
Selamat Ginting ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Dosage Form ◽  
Limit Of Detection ◽  
Fourier Transform Infrared ◽  
Metformin Hydrochloride ◽  
Infrared Spectrophotometry ◽  
Relative Standard ◽  
Limit Of Quantitation ◽  
The Fourier Transform ◽  
Tablet Dosage

The first line drug given for monotherapy for diabetes mellitus type 2 is metformin hydrochloride, which is a biguanide antihyperglycemic drug. The aim of this research was to develop, validate, and apply the Fourier Transform Infrared spectrophotometry method to identify and determine metformin hydrochloride in marketed tablet dosage form. This research included preparation of standard, analysis of samples, and validation of method. The specific wavenumber obtained for qualitative analysis was 1645.68 cm–1 and 1574.8 cm–1. The specific area obtained for quantitative analysis with a single baseline ranged from 1701.53 cm–1 to 1535.66 cm–1. All metformin hydrochloride marketed tablet dosage forms were analyzed and met all of the qualitative and quantitative requirements. The methods met the requirements of method validation for accuracy with a percentage of recovery of 100.22 %, precision with relative standard deviation of 0.48 %, linearity with a correlation coefficient of 0.9992, limit of detection of 11.17 mg per mL, limit of quantitation of 33.84 mg per mL, and good specificity results. In this study, the Fourier Transform Infrared spectrophotometry method was successfully developed and validated for application in identification and determination of metformin hydrochloride in marketed tablet dosage form.

Simultaneous Determination of Cationic and Anionic Surfactants in Domestic, Sewage and River Effluent by Diffuse Reflectance -Fourier Transform Infrared Spectroscop ic Analysis

2021 ◽  
Vol 30 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Ramsingh Kurrey ◽  
Kaushlya Thakur ◽  
Swati Chandrawanshi ◽  
Manas Kanti Deb
Keyword(s):  
Fourier Transform ◽  
Standard Deviation ◽  
Simultaneous Determination ◽  
Diffuse Reflectance ◽  
Limit Of Detection ◽  
Sodium Dodecyl ◽  
Fourier Transform Infrared ◽  
Domestic Sewage ◽  
Relative Standard

A new, simple, rapid and precise novel hyphenated diffuse reflectance-Fourier transform infrared spectroscopy (DRS-FTIR) technique for the simultaneous determination of the most frequently used cationic surfactants (CS+) i.e. cetyltrimethylammonium bromide (CTAB) and anionic surfactant (AS-) i.e. sodium dodecyl sulphate (SDS) in domestic, sewage and river wastewater samples has been stabilised. CS+ and AS- were analyzed using DRS-FTIR, the most steady and strongest vibrational IR peak at 2917.13 cm-1 for CTAB and 1226.07 for SDS were selected for the simultaneous quantiflcation of CS+ and AS- under the optimized condition such as effect of samples volume and effect of temperature. The limit of detection (LOD) and limit of quantiflcation (LOQ) of the present method were 5 µg/mL and 15 µg/mL, respectively. The absorbance and peak area were determined by the DRS-FTIR method, which shows excellent linearity with a correlation coefflcient value of 0.985 and 0.981 for the concentration range of 10-100 µg/mL. The standard deviation (SD) and relative standard deviation (RSD) for six replicate measurements were found to be 0.052 µg/L and 2.8 %, respectively.

Fourier Transform Infrared Spectrometry/Attenuated Total Reflectance Study of the Reaction of Pentanal and Propanal with 2-(Hydroxymethyl)Piperidine

1992 ◽  
Vol 46 (2) ◽  
pp. 266-272 ◽  
Author(s):  
Eugene R. Kennedy ◽  
Kevin Ashley
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Solution Phase ◽  
Attenuated Total Reflectance ◽  
Infrared Spectrometry ◽  
Fourier Transform Infrared Spectrometry ◽  
Total Reflectance ◽  
Solid Interface ◽  
Ft Ir ◽  
Flow Through

The reactions of propanal and pentanal with 2-(hydroxymethyl)piperidine were investigated by Fourier transform infrared spectrometry/attenuated total reflectance in both the solution phase and at the gas/solid interface. The reactions were studied with the use of a flow-through cylindrical internal reflection (“circle”) cell. Reaction intermediates were tentatively identified by their characteristic infrared absorption frequencies. At the gas/solid interface the reaction is thought to yield a hemiaminal intermediate. In the solution phase a hemiaminal intermediate is believed to form initially, followed by loss of water to generate an enamine product. In both gas-phase and solution-phase studies, an oxazolidine product is prepared only after an ultrasound treatment. The FT-IR/ATR technique reveals detailed mechanistic information concerning reactions between aldehydes and ethanol amines.

scholarly journals Development of Fourier transform infrared spectrophotometric method for identification and determination of marketed metamizole tablet preparation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
NERDY NERDY ◽  
EFFENDY DE LUX PUTRA ◽  
NILSYA FEBRIKA ZEBUA ◽  
CHRISTICA ILSANNA SURBAKTI ◽  
JIHAN SAFIRA
Keyword(s):  
Fourier Transform ◽  
Spectrophotometric Method ◽  
Limit Of Detection ◽  
Fourier Transform Infrared ◽  
Antiinflammatory Drug ◽  
Nonsteroidal Antiinflammatory Drug ◽  
Relative Standard ◽  
Limit Of Quantitation ◽  
Tablet Preparation

Metamizole is a nonsteroidal antiinflammatory drug (NSAID) that functions as an analgesic, antipyretic, and antiinflammatory. Examination of active substance contents is a requirement that must be met to ensure the quality of drug preparations. The aims of this study were to develop and validate the Fourier Transform Infrared spectrophotometric method for the quantitation of metamizole content in marketed tablet preparation. Identification and determination of metamizole contents by Fourier Transform Infrared spectrophotometric method used methanol solvent in the wavenumber range 4000 cm–1 to 650 cm–1. The results showed that the specific wavenumbers of metamizole were 1649.3 cm–1; 1623.3 cm–1; and 1589.7 cm–1; and the contents metamizole in marketed tablet preparation ranged from (97.954 ± 0.121)% to (104.541 ± 0.257)%. From the validation method, the recovery result is 100.129%; the relative standard deviation is 0.057%; the limit of detection is 2.09526 mg/mL; the limit of quantitation is 6.34928 mg/mL; and the range 40 mg/mL to 60 mg/mL. The quantitation of metamizole contents can be carried out by Fourier Transform Infrared spectrophotometric method with accurate and precise quantitation results.

scholarly journals A Simple Diffuse Reflectance Fourier Transform Infrared Spectroscopic Determination of Sulfur Dioxide in Ambient Air Using Potassium Tetrachloromercurate as the Absorbing Reagent

2007 ◽  
Vol 90 (4) ◽  
pp. 1180-1190
Author(s):  
Santosh Kumar Verma ◽  
Manas Kanti Deb ◽  
Samir Bajpai ◽  
Yukio Suzuki ◽  
Shekhar Kumar Sinha ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Standard Deviation ◽  
Sulfur Dioxide ◽  
Environmental Protection Agency ◽  
Diffuse Reflectance ◽  
Solid Phase ◽  
Fourier Transform Infrared ◽  
Ambient Air ◽  
Relative Standard

Abstract This paper presents development of a simple, rapid, and precise analytical method for determination of sulfur dioxide in ambient air by a gas to solid-phase conversion method. Sulfur dioxide is determined in the form of sulfite (SO32) because the absorbing reagent, potassium tetrachloromercurate (TCM), used in this method absorbs sulfur dioxide from the atmosphere in the form of sulfite. Determination of submicrogram levels of sulfur dioxide was based on the selection of a quantitative analytical peak at 495 cm1 among the 3 observed vibrational peaks for the dichlorosulfitomercurate complex formed after reaction of sulfur dioxide with TCM and measurement of absorbance using diffuse reflectance Fourier transform infrared spectroscopy. The limits of detection and quantification of the method were found to be 0.09 and 0.4 g/g SO32, respectively. The precision in terms of standard deviation and relative standard deviation (RSD) at a level of 2 g SO32/0.1 g KBr for n = 10 was found to be 0.036 g SO32 and 1.8%, respectively. The RSD (n = 10) for determination of sulfur dioxide in ambient air was observed to be in the range of 2.74.2%. The method proposed is time saving and eliminates the slow and cumbersome steps of pH maintenance of the reaction mixture and color formation of the U.S. Environmental Protection Agency recommended West and Gaeke spectrophotometric method and other methods for quantitative determination of sulfur dioxide.

FR-IR Molecular Microanalysis System

1990 ◽  
Vol 48 (2) ◽  
pp. 270-271
Author(s):  
John A. Reffner ◽  
William T. Wihlborg
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Integrated System ◽  
Morphological Examination ◽  
Fully Integrated ◽  
Ir Microscopy ◽  
Normal Functions ◽  
Infrared Microspectroscopy ◽  
Infrared Spectral ◽  
Ft Ir

The IRμs™ is the first fully integrated system for Fourier transform infrared (FT-IR) microscopy. FT-IR microscopy combines light microscopy for morphological examination with infrared spectroscopy for chemical identification of microscopic samples or domains. Because the IRμs system is a new tool for molecular microanalysis, its optical, mechanical and system design are described to illustrate the state of development of molecular microanalysis. Applications of infrared microspectroscopy are reviewed by Messerschmidt and Harthcock.Infrared spectral analysis of microscopic samples is not a new idea, it dates back to 1949, with the first commercial instrument being offered by Perkin-Elmer Co. Inc. in 1953. These early efforts showed promise but failed the test of practically. It was not until the advances in computer science were applied did infrared microspectroscopy emerge as a useful technique. Microscopes designed as accessories for Fourier transform infrared spectrometers have been commercially available since 1983. These accessory microscopes provide the best means for analytical spectroscopists to analyze microscopic samples, while not interfering with the FT-IR spectrometer’s normal functions.

Calcium/Copper alginate framework doped with CuO nano-particles as a novel adsorbent for micro-extraction of benzodiazepines from human serum

2020 ◽  
Vol 16 ◽  
Author(s):  
Nadereh Rahbar ◽  
Fatemeh Ahmadi ◽  
Zahra Ramezani ◽  
Masoumeh Nourani
Keyword(s):  
Human Serum ◽  
High Performance ◽  
Limit Of Detection ◽  
Solid Phase ◽  
Nano Particles ◽  
Limit Of Quantification ◽  
Analytical Methodology ◽  
Fiber Fabrication ◽  
Relative Standard ◽  
Green Procedure

Background: Sample preparation is one of the most challenging phases in pharmaceutical analysis, especially in biological matrices, affecting the whole analytical methodology. Objective: In this study, a new Ca(II)/Cu(II)/alginate/CuO nanoparticles hydrogel fiber (CCACHF) was synthesized through a simple, green procedure and applied for fiber micro solid phase extraction (FMSPE) of diazepam (DIZ) and oxazepam (OXZ) as model drugs prior to high-performance liquid chromatography-UV detection (HPLC-UV). Methods: Composition and morphology of the prepared fiber were characterized and the effect of main parameters on the fiber fabrication and extraction efficiency have been studied and optimized. Results: In optimal conditions, calibration curves were linear ranging between 0.1–500 µg L−1 with regression coefficients of 0.9938 and 0.9968. Limit of detection (LOD) (S/N=3) and limit of quantification (LOQ) (S/N=10) of the technique for DIZ and OXZ were 0.03 to 0.1 µg L−1. Within-day and between-day relative standard deviations (RSDs) for DIZ and OXZ were 6.0–12.5% and 3.3–9.4%, respectively. Conclusion: The fabricated adsorbent has been substantially employed to extraction of selected benzo-diazepines (BZDs) from human serum real specimens and the obtained recoveries were also satisfactory (82.1-109.7%).

scholarly journals A highly sensitive octopus-like azobenzene fluorescent probe for determination of abamectin B1 in apples

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zhenlong Guo ◽  
YiFei Su ◽  
Kexin Li ◽  
MengYi Tang ◽  
Qiang Li ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Limit Of Detection ◽  
Quantitative Detection ◽  
Fluorescence Signal ◽  
Ionization Mass ◽  
Limit Of Quantification ◽  
Visible Absorption ◽  
Esi Ms ◽  
Relative Standard ◽  
Ft Ir

AbstractThe development of detecting residual level of abamectin B1 in apples is of great importance to public health. Herein, we synthesized a octopus-like azobenzene fluorescent probe 1,3,5-tris (5′-[(E)-(p-phenoxyazo) diazenyl)] benzene-1,3-dicarboxylic acid) benzene (TPB) for preliminary detection of abamectin B1 in apples. The TPB molecule has been characterized by ultraviolet–visible absorption spectrometry, 1H-nuclear magnetic resonance, fourier-transform infrared (FT-IR), electrospray ionization mass spectroscopy (ESI-MS) and fluorescent spectra. A proper determination condition was optimized, with limit of detection and limit of quantification of 1.3 µg L−1 and 4.4 μg L−1, respectively. The mechanism of this probe to identify abamectin B1 was illustrated in terms of undergoing aromatic nucleophilic substitution, by comparing fluorescence changes, FT-IR and ESI-MS. Furthermore, a facile quantitative detection of the residual abamectin B1 in apples was achieved. Good reproducibility was present based on relative standard deviation of 2.2%. Six carboxyl recognition sites, three azo groups and unique fluorescence signal towards abamectin B1 of this fluorescent probe demonstrated reasonable sensitivity, specificity and selectivity. The results indicate that the octopus-like azobenzene fluorescent probe can be expected to be reliable for evaluating abamectin B1 in agricultural foods.

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