scholarly journals Use of Non-Invasive Parameters of Non-Alcoholic Steatohepatitis and Liver Fibrosis in Daily Practice - An Exploratory Case-Control Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e111551 ◽  
Author(s):  
Karel Dvorak ◽  
Jan Stritesky ◽  
Jaromir Petrtyl ◽  
Libor Vitek ◽  
Renata Sroubkova ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Case Control Study ◽  
Daily Practice ◽  
Case Control ◽  
Non Invasive ◽  
Alcoholic Steatohepatitis ◽  
Control Study

scholarly journals Identifying Possible Hepatic Fibrosis of Hepatitis B Origin Using Non-invasive Markers: A Case-control Study in the South West Region of Cameroon

2019 ◽  
pp. 1-12
Author(s):  
Kukwah Anthony Tufon ◽  
Henry Dilonga Meriki ◽  
Kwenti Emmanuel Tebit ◽  
Teuwafeu Denis Georges ◽  
Nyeke James Tony ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Hepatitis B ◽  
Hepatic Fibrosis ◽  
Case Control Study ◽  
Case Control ◽  
Non Invasive ◽  
West Region ◽  
South West ◽  
Control Study ◽  
South West Region

Aim: HBV infection is known to cause liver fibrosis as well as some extrahepatic manifestations. We aimed at assessing hematological changes and identifying possible hepatic fibrosis of Hepatitis B origin using non-invasive markers (NIMs). Study Design: A hospital-based Case-control study Place and Duration of Study: Conducted at the Buea Regional Hospital, South West Region of Cameroon from February 2016 to December 2017 Methods: We enrolled HBV infected treatment naïve patients and “healthy” controls. All participants were subjected to alanine aminotransferase (ALT) and aspartate aminotransferase (AST) measurement, Full blood count (FBC), HBsAg, anti-HBc, HIV and HCV tests. Aspartate-platelet ratio index (APRI), fibrosis based on 4 factors (FIB-4), age-platelet index (API) and AST/ALT ratio (AAR) were generated from the test results. A questionnaire was administered to collect demographic data, alcohol consumption and history of liver/kidney disease or metabolic syndrome. Results: A total of 202 cases and 202 controls were enrolled. Hematocrit (HCT) was significantly higher (p<0.001) in cases than controls. The controls had significantly higher mean values for platelet (p=0.005), neutrophil (p=0.032) and number of individuals with AST/ALT ratio (AAR) ≥1. Liver fibrosis was significantly associated with cases than controls based on APRI (OR:6.06, CI:3.59-10.24), FIB-4 (OR:5.35, CI:2.75-10.39) and API (OR:8.02, CI:1.81-35.55). Among the HBV infected cases, 69 (34.2%), 36(17.8%) and 8(4.0%) had results indicative of fibrosis from at least 2, at least 3 and all 4 NIMs respectively. AAR detected possible fibrosis in 136 HBV infected cases of which up to 77 (56.6%) were not detected as fibrosis by the other NIMs. Conclusion: HBV infection affects neutrophil percentage, HCT, PLT, APRI, FIB-4 and API in our study population. AAR did not prove to be a reliable NIM. Using at least 3 NIMs for HBV infected patients can significantly scale up their reliability for determining liver fibrosis in clinical practice.

Acceptance of a new non-invasive fetal monitoring system and attitude for telemedicine approaches in obstetrics: a case–control study

2018 ◽  
Vol 298 (6) ◽  
pp. 1085-1093 ◽  
Author(s):  
Katharina Schramm ◽  
Florian Lapert ◽  
Juliane Nees ◽  
Carlijn Lempersz ◽  
S. Guid Oei ◽  
...  
Keyword(s):  
Monitoring System ◽  
Case Control Study ◽  
Fetal Monitoring ◽  
Case Control ◽  
Non Invasive ◽  
Control Study

548 A new non-invasive technique in primary sclerosing cholangitis (PSC): A case-control study

2004 ◽  
Vol 40 ◽  
pp. 161
Author(s):  
V. Macchi ◽  
E. Bezzon ◽  
A. Floreani ◽  
R. Pasini ◽  
P. Marchesi ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Case Control Study ◽  
Case Control ◽  
Invasive Technique ◽  
Non Invasive ◽  
Control Study

scholarly journals The Copenhagen case-control study of bladder cancer: role of smoking in invasive and non-invasive bladder tumours.

1987 ◽  
Vol 41 (1) ◽  
pp. 30-36 ◽  
Author(s):  
O M Jensen ◽  
J Wahrendorf ◽  
M Blettner ◽  
J B Knudsen ◽  
B L Sorensen
Keyword(s):  
Bladder Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Non Invasive ◽  
Control Study ◽  
Bladder Tumours

scholarly journals Quality of Life and Anxious-depressive Symptoms in Cancer Patients Undergoing Mindfulness-based Interventions: Feasibility and Preliminary Outcomes on Prospective Single-centre Case-control Study (MIND4ME St.)

2017 ◽  
Vol 41 (S1) ◽  
pp. S252-S252
Author(s):  
G. Pontoni ◽  
M. Maur ◽  
R. Ferrari ◽  
A. Guida ◽  
S. Poletti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Cancer Patients ◽  
Case Control Study ◽  
Psychological Symptoms ◽  
Daily Practice ◽  
Case Control ◽  
Depression And Anxiety ◽  
Control Study

BackgroundMindfulness based interventions (MBIs) have shown efficacy in improving psychological symptoms including depression and anxiety in cancer patients (pts). The study aimed to explore feasibility and reproducibility of MBIs in an Italian Cancer Centre measuring biochemical and psychological parameters.MethodsIn this pilot prospective case-control study, we recruited newly diagnosed pts receiving adjuvant chemotherapy (CT). A MBIs program was designed consisting of 2.5 hours weekly for 8 weeks and, including meditation, yoga and body scan. Material for 45 minutes (mn) home daily practice was provided. Primary endpoint was to evaluate feasibility. Secondary endpoints were assessment of quality of life (QoL), psychological and biochemical outcomes of stress, tested at baseline (W0), W4, W8, W24, W48. PSS (Perceived Stress Reduction), POMS (profile of mood states scores), EuroQoL (EQ-5D-3L) were administered.ResultsTen pts underwent MBIs program arm. We present preliminary results, while data of control arm are being collected. All pts were female, two pts (20%) dropped out. Median age was 56 years. All received adjuvant CT, 5/8 received radiotherapy and hormone therapy. Mean of sessions attending was 6.8 (76%). Median daily practice was 30 mn. EQ-5D item for depression and anxiety showed decreasing trend in mean score from moderate to light (P = 0.15) and significant improvement of auto-perceived QoL was observed comparing W0 and W8 (P = 0.02)ConclusionsIn a sensitive setting such as start CT, we found high pts compliance to MBIs. Improvement in self-perceived QoL after starting program was found and comparing anxious-depressive symptoms outcomes with control arm is still needed.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: A case–control study

2010 ◽  
Vol 53 (6) ◽  
pp. 1035-1040 ◽  
Author(s):  
David Laharie ◽  
Julien Seneschal ◽  
Thierry Schaeverbeke ◽  
Marie-Sylvie Doutre ◽  
Maïté Longy-Boursier ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Case Control Study ◽  
Transient Elastography ◽  
Inflammatory Diseases ◽  
Case Control ◽  
Chronic Inflammatory Diseases ◽  
Control Study
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