scholarly journals Characteristics and prognosis of primary treatment-naïve oral cavity squamous cell carcinoma in Norway, a descriptive retrospective study

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227738 ◽  
Author(s):  
Inger-Heidi Bjerkli ◽  
Olav Jetlund ◽  
Gunnhild Karevold ◽  
Ása Karlsdóttir ◽  
Ellen Jaatun ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Retrospective Study ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Treatment ◽  
Treatment Naïve

Histopathological spectrum of oral cavity lesions – A tertiary care experience

2021 ◽  
Vol 8 (3) ◽  
pp. 364-368
Author(s):  
Ishani Gupta ◽  
Rekha Rani ◽  
Jyotsna Suri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Retrospective Study ◽  
Oral Cancer ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Proper Management ◽  
The World ◽  
One Year

Oral cancer is one of a major health problem in some parts of the world especially in the developing countries. Oral cancer is the sixth most common cancer in the world whereas in India it is one of the most prevalent cancer. Oral cavity lesions are usually asymptomatic. Accurate diagnosis of the lesion is the first step for the proper management of patients and histopathology is considered as the gold standard. The objective is to study the different patterns of oral cavity lesions seen in a tertiary care hospital of Jammu: One year retrospective study. Post graduate department of pathology.: It was a retrospective study carried out in a tertiary care centre for a period of one year from March 2020 to Feb 2021. 148 cases of oral cavity lesions were included in this study. The parameters that were included in the study were sociodemographic data, site of the lesion, clinical features and histological diagnosis. Data collected was analysed.148 cases of oral lesions were identified during the period of study. The age of patients varied from 5 to 78years and Male to Female ratio was 2.2:1. Buccal mucosa (30%) was the most common site involved which was followed by tonsil (19%). Out of 148 cases 70 cases were malignant, 10 cases pre malignant and 21 cases were benign. Squamous cell carcinoma (33.7%) was the most common lesion present in our study. Oral cavity lesions have a vast spectrum of diseases which range from tumour like lesions to benign and malignant tumours. Our study concluded that squamous cell carcinoma was the most common malignant lesion of oral cavity. Histological typing of the lesion is important for confirmation of malignancy and it is essential for the proper management of the patient.

scholarly journals Choice of Levels in Selective Neck Dissection and Its Impact On Regional Control and Survival in 661 Patients With Head and Neck Squamous Cell Carcinoma

2021 ◽  
Author(s):  
Mattis Bertlich ◽  
Nina Zeller ◽  
Saskia Freytag ◽  
Bernhard G. Weiss ◽  
Martin Canis ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Primary Treatment ◽  
Selective Neck Dissection ◽  
Regional Control ◽  
Level I

Abstract Background: Selective Neck Dissection (SND) is the surgical treatment of choice in suspected or manifest nodal positive squamous cell carcinoma of the head and neck (HNSCC). For SND to be successful, treated levels should be selected accordingly. Aim of this study was to identify neck dissection levels that had an impact on the individual prognosis.Methods: We conducted a retrospective review of SND as part of primary treatment of HNSCC. Overall survival (OS) and regional control rates (RCR) were calculated for all patients.Results: 661 patients with HNSCC were included, 644 underwent ipsilateral and 319 contralateral SND. Average follow up was 78.9 ± 106.4 months. 67 (10.1%) patients eventually developed nodal recurrence. Tumor sites were oral cavity (135), oropharynx (179), hypopharynx (118) and larynx (229). Tumor categories pT1 – pT4a, and all clinical and pathological nodal categories were included. Multivariate analysis indicated improved OS rates for patients undergoing SND in ipsilateral levels I and V as well as level III contralaterally. Analysis for tumor origin showed that SND in ipsilateral level I showed a significantly improved OS in HNSCC of the oral cavity.Conclusion: In HNSCC of the oral cavity, ipsilateral level I needs to be included when performing SND.

LOCAL COMPLICATIONS OF RADIATION AND CHEMOTHERAPY TREATMENT OF PATIENTS WITH SQUAMOUS CELL CARCINOMA OF THE MUCOSA OF THE ORAL CAVITY

2018 ◽  
Vol 64 (2) ◽  
pp. 166-170
Author(s):  
Yekaterina Kochurova ◽  
Aleksandr Mukhanov
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Integrated Approach ◽  
Primary Treatment ◽  
Considerable Effect ◽  
Team Approach ◽  
Chemotherapy Drugs ◽  
Prevention Methods

Question on comprehensive dental care to patients with squamous cell carcinoma (SCC) of the mucous membrane of the oral cavity (MMOC) showed the importance of a team approach of physicians of allied specializations, careful planning and consistent implementation of rehabilitation treatment stages of cancer. The implementation of preventive measures showed a reduced severity or absence of complications conducted by the primary treatment. The data about the important role of preoperative sanitation of the oral cavity are presented. There are described the pathogenesis of the most common complications and identified effective methods of prevention and treatment, as well as the mechanisms of action of different prevention methods. Characteristic signs of “radiation caries”, oral mucositis, dysgeusia, xerostomia, lockjaw chewing muscles, osteoradionecrosis, dysphagia and neurotoxic effects of chemotherapy drugs are marked. It is necessary to emphasize the considerable effect of such complications on quality of life of patients after treatment. This again proves a need for an integrated approach and participation in the work of the specialists of a number of related disciplines.

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