scholarly journals Prevalence of hypertension and its determinants in Ethiopia: A systematic review and meta-analysis

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244642
Author(s):  
Sofonyas Abebaw Tiruneh ◽  
Yeaynmarnesh Asmare Bukayaw ◽  
Seblewongel Tigabu Yigizaw ◽  
Dessie Abebaw Angaw

Introduction Hypertension is a major public health problem globally and it is a leading cause of death and disability in developing countries. This review aims to estimate the pooled prevalence of hypertension and its determinants in Ethiopia. Methods A systematic literature search was conducted at the electronic databases (PubMed, Hinari, and Google Scholar) to locate potential studies. Heterogeneity between studies checked using Cochrane Q test statistics and I2 test statistics and small study effect were checked using Egger’s statistical test at 5% significance level. Sensitivity analysis was checked. A random-effects model was employed to estimate the pooled prevalence of hypertension and its determinants in Ethiopia. Results In this review, 38 studies that are conducted in Ethiopia and fulfilled the inclusion criteria with a total number of 51,427 study participants were reviewed. The overall pooled prevalence of hypertension in the country was 21.81% (95% CI: 19.20–24.42, I2 = 98.35%). The result of the review also showed that the point of prevalence was higher among males (23.21%) than females (19.62%). When we see the pervasiveness of hypertension from provincial perspective; the highest prevalence of hypertension was observed in Addis Ababa (25.35%) and the lowest was in Tigray region (15.36%). In meta-regression analysis as the mean age increases by one year, the likelihood of developing hypertension increases by a factor of 0.58 times (β = 0.58, 95% CI: 0.31–0.86, R2 = 36.67). Male sex (OR = 1.29, 95% CI: 1.03–1.61, I2 = 81.35%), age > 35 years (OR = 3.59, 95% CI: 2.57–5.02, I2 = 93.48%), overweight and/or obese (OR = 3.34, 95% CI: 2.12–5.26, I2 = 95.41%), khat chewing (OR = 1.42, 95% CI: I2 = 62%), alcohol consumption (OR = 1.50, 95% CI: 1.21–1.85, I2 = 64%), family history of hypertension (OR = 2.56, 95% CI: 1.64–3.99, I2 = 83.28%), and family history of diabetes mellitus (OR = 3.69, 95% CI: 1.85–7.59, I2 = 89.9%) are significantly associated with hypertension. Conclusion Hypertension is becoming a major public health problem in Ethiopia. Nearly two out of ten individuals who are older than 18 years living with hypertension. Sex, age, overweight and/or obese, khat chewing, alcohol consumption, and family history of hypertension and diabetes mellitus are statistically significant determinant factors for hypertension in Ethiopia. Primary attention should be given for behavioral risk factors to tackle the alarming increase of hypertension in Ethiopia.

Author(s):  
Ummu Fatihah Ammutammima ◽  
◽  
Didik Gunawan Tamtomo ◽  
Bhisma Murti ◽  
◽  
...  

Background: Gestational diabetes mellitus (GDM) is a major public health problem because of its associated complications during pregnancy. Studies have suggested that women with positive parental history of diabetes may be predisposed to an increased GDM risk. This study aimed to examine the correlation between family history with diabetes mellitus and the gestational diabetes mellitus. Subjects and Method: This was a meta-analysis and systematic review. The study was collected articles from PubMed, Science Direct, and Google Scholar databases, from year 2017 to 2020. Keywords used “gestational diabetes mellitus” OR “GDM” AND “pregnancy induced diabetes” AND “family history of diabetes” AND “crosssectional”. The study subject was pregnant women. Intervention was family history with diabetes mellitus with comparison no family history of diabetes mellitus. The study outcome was gestational diabetes mellitus. The articles were selected by PRISMA flow chart. The quantitative data were analyzed by ReVman 5.3. Results: 7 studies from Kuwait, Ethiopia, Fiji, Malaysia, and China, reported that family history with diabetes mellitus increased the risk of gestational diabetes mellitus (aOR= 1.68; 95% CI= 0.87 to 3.26; p= 0.120). Conclusion: Family history with diabetes mellitus increases the risk of gestational diabetes mellitus. Keywords: gestational diabetes mellitus, pregnancy induced diabetes, family history of diabetes Correspondence: Ummu Fsatihah Ammutammima. Masters Program Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 081717252573. DOI: https://doi.org/10.26911/the7thicph.05.54


1993 ◽  
Vol 11 (5) ◽  
pp. S308???S309 ◽  
Author(s):  
Burkhard Weisser ◽  
Stefan Griine ◽  
Thomas Sp??hler ◽  
Thomas Kistler ◽  
Wilhelm Vetter

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Yudhaputra Setiadhi ◽  
Shirley E.S. Kawengian ◽  
Nelly Mayulu

Abstract: Hypertension is a condition where the systolic blood pressure is >140mmHg and the diastolic blood pressure is >90mmHg measured by a sphygmomanometer. The measurements were performed at least 2 times in a span of one week. Uncontrolled hypertension can cause damage to the arteries, damage to the heart, damage to the brain, kidneys and eyes, as well as accelerating the onset of chronic cardiovascular diseases. Hypertension in pregnancy could affect such things as reduced blood flow to the placenta, fetal growth restriction, premature birth, fetal death, and increased risk of cardiovascular disease. One of the factors that affect the risk of hypertension is a family history of hypertension.The study aimed to see whether there is a relationship between a family history of hypertension and hypertension in pregnancy. The data were collected using cross-sectional method. This cross-sectional study was conducted in September-November 2016, in Bahu Public Health Center, Ranotana Public Health Center, Tuminting Public Health Center, Kombos Public Health Center, and Paniki Public Health Center. The sample were taken with total sampling method, with the total number of respondents that are willing around 144 respondent. Based on the research, from 50 respondent with a family history of hypertension, 1 respondent (2%) belong to the category of stage 1 hypertension, 20 respondent (40%) belong to the category of pre-hypertension and 29 respondents (58%) were normal. Conclusion: Based on the results, it can be deduced that a family history of hypertension mostly did not affect the incidence of hypertension in pregnant woman.Keywords: hypertension, maternal hypertension, family history of hypertension  Abstrak: Hipertensi merupakan keadaan dimana tekanan darah sistolik >140mmHg dan tekanan darah diastolik >90mmHg yang diukur dengan sphygmomanometer. Pengukuran dilakukan minimal 2 kali dalam rentang waktu 1 minggu. Hipertensi yang tidak terkontrol dapat menyebabkan kerusakan pada pembuluh darah arteri, kerusakan pada jantung, kerusakan pada otak, ginjal dan mata, serta mempercepat terjadinya penyakit kardiovaskular yang kronis. Hipertensi pada wanita hamil dapat mempengaruhi beberapa hal seperti aliran darah ke plasenta berkurang, pertumbuhan janin terhambat, kelahiran prematur, bayi meninggal dalam kandungan, dan meningkatnya risiko terkena penyakit kardiovaskular. Salah satu faktor rikiko yang mempengaruhi hipertensi adalah riwayat hipertensi pada keluarga. Penelitian ini bertujuan untuk melihat apakah ada hubungan antara riwayat hipertensi pada keluarga dan hipertensi pada kehamilan. Pengambilan data dilakukan dengan menggunakan metode cross-sectional. Penelitian cross-sectional ini dilakukan pada bulan September-November 2016 di Puskesmas Bahu, Puskesmas Ranotana, Puskesmas Tuminting, Puskesmas Kombos dan Puskesmas Paniki. Pengambilan sampel dilakukan berdasarkan dengan metode total sampling dengan jumlah responden yang bersedia sebanyak 144 orang. Berdasarkan penelitian didapatkan dari 50 responden dengan riwayat hipertensi pada keluarga 1 responden (2%) masuk ke dalam kategori hipertensi stadium 1, 20 responden (40%) masuk ke dalam kategori pre-hipertensi dan 29 responden (58%) yang normal. Simpulan: Berdasarkan hasil tersebut, dapat ditarik kesimpulan bahwa riwayat hipertensi pada keluarga sebagian besar tidak mempengaruhi angka kejadian hipertensi pada ibu hamilKata kunci: hipertensi, hipertensi kehamilan, riwayat hipertensi pada keluarga


2014 ◽  
Vol 21 (2) ◽  
pp. 137-150 ◽  
Author(s):  
Ilie-Robert Dinu ◽  
Eugen Moţa

Abstract Diabetes mellitus represents a major public health problem in the world and glycemic control is very important in subjects with diabetes. Glycation of many proteins is increased in subjects with diabetes compared with persons without diabetes. Glycated albumin (GA) has emerged as a possible glycation index for intermediate-term diabetes control. There is evidence that GA can be considered a better parameter than glycated haemoglobin in many conditions including pregnancy, chronic kidney disease, liver diseases and anemia. Several reports indicate that GA plays a role in the pathogeny of diabetes complications, mainly in diabetic nephropathy and retinopathy. There are several limitations for using GA including the lack of standardization in the laboratories. Several studies are needed in order to understand the place of GA in the pathogeny of diabetes complications and the role in assessing the metabolic control


2018 ◽  
Vol 8 (2) ◽  
pp. 94-100
Author(s):  
NS Neki ◽  
Riponjot Singh ◽  
Satpal Aloona ◽  
Bhupinder Singh ◽  
Sargun Singh Walia ◽  
...  

Diabetes mellitus (DM) is a chronic metabolic condition and a major public health problem. It is associated with many musculoskeletal manifestations which are usually under-recognized and poorly treated, as compared to other complications like neuropathy, nephropathy and retinopathy. These manifestations affect the joints, soft tissues and the bones leading to alterations in musculoskeletal system of the patient. This article reviews the major rheumatological problems of diabetes mellitus including their management.J Enam Med Col 2018; 8(2): 94-100


2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Addisu Alehegn Alemu ◽  
Liknaw Bewket Zeleke ◽  
Bewket Yesarah Aynalem ◽  
Getachew Mullu Kassa

Background. Hepatitis B virus (HBV) is an infectious and a global public health problem. The prevalence of HBV infection among pregnant women is between 2.3% and 7.9%. HBV infection during pregnancy is associated with prenatal transmission to the fetus. HBV has an effective vaccine which reduces up to 96% of the transmission. Although different studies were conducted in Ethiopia, none of them showed the national prevalence of HBV infection among pregnant women. Therefore, this study was conducted to determine the pooled prevalence of HBV and its associated factors in Ethiopia. Methods. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for articles. All observational published studies were retrieved using relevant search terms in Google Scholar, African Online Journal, CINAHL, and PubMed databases. Newcastle-Ottawa assessment checklist for observational studies was used for critical appraisal of the included articles. The meta-analysis was done with STATA version 14 software. The I2 statistics were used to test heterogeneity whereas Begg’s and Egger’s tests were used to assess publication bias. Odds ratio (OR) with a 95% confidence interval (CI) was presented using the forest plot. Results. A total of twenty-three studies were included in this systematic review and meta-analysis. The pooled prevalence of HBV in Ethiopia was 4.75% (95% CI: 4.06, 5.44). The subgroup analysis showed a higher prevalence of HBV infection among pregnant women in Gambella (7.9%) and the lowest in Southern Nations, Nationalities, and Peoples’ Region (SNNPR) (2.3%). Associated factors with HBV infection include history of multiple sexual partner (OR=6.02 (95%CI=3.86, 9.36)), blood transfusion history (OR=5.71 (95%CI=3.25, 10.04)), abortion history (OR=3.58 (95%CI=2.10, 6.09)), and history of body tattoo (OR=2.83 (95%CI=1.55, 5.17)). Conclusions. HBV infection among pregnant women is a common public health problem in Ethiopia. Multiple sexual partners, abortion history, blood transfusion history, and body tattoo were significantly associated with HBV infection. Policies and strategies should focus on factors identified in this study to improve the prevention of HBV among pregnant women.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Melkamu A. Zeru ◽  
Endalamaw Tesfa ◽  
Aweke A. Mitiku ◽  
Awoke Seyoum ◽  
Tesfaye Abera Bokoro

AbstractDiabetes mellitus (DM) is a public health problem in developing as well as developed nations. DM leads to many complications that are associated with higher morbidity and mortality worldwide. Therefore, the current study was planned to assess the prevalence and risk factors of type-2 DM in Ethiopian population. Six electronic databases such as: PubMed, Scopus, Hinari, Web of science, Google Scholar, and African Journals Online were searched for studies published in English up December 30, 2020. Newcastle–Ottawa Scale was used for quality assessment of the included studies. The data was extracted by Microsoft excel and analyzed through Stata version 16 software. The random effect meta-regression analysis was computed at 95% CI to assess the pooled prevalence and risk factors of type-2 DM. Forty observational studies were included in this systematic review and meta-analysis. The pooled prevalence of DM in Ethiopia was 6.5% (95% CI (5.8, 7.3)). The sub-group analysis revealed that the highest prevalence of DM was found in Dire Dawa city administration (14%), and the lowest prevalence was observed in Tigray region (2%). The pooled prevalence of DM was higher (8%) in studies conducted in health facility. Factors like: Age ≥ 40 years ((Adjusted Odds Ratio (AOR): 1.91 (95% CI: 1.05, 3.49)), Illiterate (AOR: 2.74 (95% CI: 1.18, 6.34)), Cigarette smoking (AOR: 1.97 (95% CI: 1.17, 3.32)), Body mass index (BMI) ≥ 25 kg/m2 (AOR: 2.01 (95 CI: 1.46, 2.27)), family history of DM (AOR: 6.14 (95% CI: 2.80, 13.46)), history of hypertension (AOR: 3.00 (95% CI: 1.13, 7.95)) and physical inactivity (AOR: 5.79 (95% CI: 2.12, 15.77)) were significantly associated with type-2 DM in Ethiopian population. In this review, the prevalence of type-2 DM was high. Factors like: Older age, illiteracy, cigarette smoking, MBI ≥ 25, family history of DM, history of hypertension and physical inactivity were an identified risk factors of type-2 DM. Therefore, health education and promotion will be warranted. Further, large scale prospective studies will be recommended to address possible risk factors of type-2 DM in Ethiopian population.


2021 ◽  
Author(s):  
Destaw Fetene Teshome ◽  
Shitaye Alemu Balcha ◽  
Tadesse Awoke Ayele ◽  
Asmamaw Atnafu ◽  
Mekonnen Sisay ◽  
...  

Abstract Background: Estimating prevalence and identifying risk factors of hypertension are paramount important to develop strategies to prevent hypertensive disease. Although, hypertension is a major public health problem in Ethiopia, there is scarcity of evidence in rural areas of the country. Hence, this study is aimed to assess the prevalence and risk factors of hypertension among adult population in rural districts of northwest Ethiopia.Methods: Community based cross sectional study was conducted from June to October, 2020. Multistage cluster sampling technique was used to select 1177 study participants. A face to face interview was conducted using an adapted version of the WHO STEPwise approach questionnaire. The blood pressure was measured three times using aneroid sphygmomanometer and the mean of the last two readings were used for the analysis. Data were entered using Epidata and analyzed using STAT-14. Multivariable logistic regression was used to identify risk factors associated with hypertension.Results: Of the total participants, 218(18.5%) were found to be hypertensive. The prevalence of hypertension consistently increased with age. Hypertension was positively and significantly associated with female sex ((adjusted odd ratio (AOR)=2.30, 95% CI: 1.53, 3.45)), age group 45-54 years (AOR=4.63, 95% CI: 1.01, 21.37), 55-64 years (AOR=14.40, 95% CI: 3.07, 67.63), ³65 years (AOR=19.37, 95% CI: 4.03, 93.09), having history of alcohol consumption (AOR=3.25, 95% CI: 1.17, 9.02), used much amount of salt (AOR=2.37, 95% CI: 1.53, 3.60), used too much amount of salt (AOR=3.78, 95% CI: 1.85, 7.72), sleeping for a short duration (AOR=2.05, 95%CI: 1.30, 3.24), and having Family history of hypertension (AOR=2.12, 95% CI; 1.32, 3.39). Conclusions: Hypertension was significantly high among the rural population we studied and is emerging as a public health problem in rural areas. Female sex, older age, ever used alcohol, used much and too much amount of salt, inadequate sleep, and family history of hypertension were factors positively and significantly associated with hypertension. We recommend local health authorities integrate promotion of hypertension health education, lifestyle modification intervention on salt and alcohol reduction, and hypertension detection particularly for female and elderly population at health post level to avert the problem.


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