scholarly journals Reproducibility of magnetic resonance fingerprinting-based T1 mapping of the healthy prostate at 1.5 and 3.0 T: A proof-of-concept study

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245970
Author(s):  
Nikita Sushentsev ◽  
Joshua D. Kaggie ◽  
Rhys A. Slough ◽  
Bruno Carmo ◽  
Tristan Barrett
Keyword(s):  
Magnetic Resonance ◽  
Imaging Techniques ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Proof Of Concept ◽  
Concept Study ◽  
3.0 T ◽  
Cross System ◽  
3.0 T Mri ◽  
Field Strengths

Facilitating clinical translation of quantitative imaging techniques has been suggested as means of improving interobserver agreement and diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) of the prostate. One such technique, magnetic resonance fingerprinting (MRF), has significant competitive advantages over conventional mapping techniques in terms of its multi-site reproducibility, short scanning time and inherent robustness to motion. It has also been shown to improve the detection of clinically significant prostate cancer when added to standard mpMRI sequences, however, the existing studies have all been conducted on 3.0 T MRI systems, limiting the technique’s use on 1.5 T MRI scanners that are still more widely used for prostate imaging across the globe. The aim of this proof-of-concept study was, therefore, to evaluate the cross-system reproducibility of prostate MRF T1 in healthy volunteers (HVs) using 1.5 and 3.0 T MRI systems. The initial validation of MRF T1 against gold standard inversion recovery fast spin echo (IR-FSE) T1 in the ISMRM/NIST MRI system revealed a strong linear correlation between phantom-derived MRF and IR-FSE T1 values was observed at both field strengths (R2 = 0.998 at 1.5T and R2 = 0.993 at 3T; p = < 0.0001 for both). In young HVs, inter-scanner CVs demonstrated marginal differences across all tissues with the highest difference of 3% observed in fat (2% at 1.5T vs 5% at 3T). At both field strengths, MRF T1 could confidently differentiate prostate peripheral zone from transition zone, which highlights the high quantitative potential of the technique given the known difficulty of tissue differentiation in this age group. The high cross-system reproducibility of MRF T1 relaxometry of the healthy prostate observed in this preliminary study, therefore, supports the technique’s prospective clinical validation as part of larger trials employing 1.5 T MRI systems, which are still widely used clinically for routine mpMRI of the prostate.

scholarly journals Usefulness of the fast spin-echo three-point Dixon (mDixon) image of the knee joint on 3.0-T MRI: comparison with conventional fast spin-echoT2weighted image

2016 ◽  
Vol 89 (1062) ◽  
pp. 20151074 ◽  
Author(s):  
Hee J Park ◽  
So Y Lee ◽  
Myung H Rho ◽  
Eun C Chung ◽  
Jin H Ahn ◽  
...  
Keyword(s):  
Knee Joint ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
3.0 T ◽  
Fast Spin ◽  
3.0 T Mri

The ongoing dilemma of residual cholesteatoma detection: are current magnetic resonance imaging techniques good enough?

2010 ◽  
Vol 124 (12) ◽  
pp. 1300-1304 ◽  
Author(s):  
M P A Clark ◽  
B D Westerberg ◽  
D M Fenton
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Residual Disease ◽  
Imaging Techniques ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Resonance Imaging ◽  
Second Look ◽  
Diffusion Weighted ◽  
Echo Planar

AbstractIntroduction:There is a clear clinical need to reliably detect residual cholesteatoma after canal wall up mastoid surgery. Ideally, this would be achieved through non-invasive radiological means rather than second-look surgery, thus preventing morbidity in those patients in whom no residual disease is found.Case report:We describe a case in which non-echo-planar, diffusion-weighted magnetic resonance imaging sequences were used pre-operatively, and compared with subsequent surgical findings. This case highlights both the potential of this increasingly popular magnetic resonance technique and also its current limitations.Discussion:Various magnetic resonance sequencing types have been employed to try to reliably detect residual cholesteatoma, each with varying success. Non-echo-planar, fast-spin echo, diffusion-weighted sequences currently appear to be the most reliable at detecting even the smallest pearl of cholesteatoma, down to 2 mm in diameter. In our unit, a propeller, diffusion-weighted image sequence is employed on a GE Signa scanner. However, both this case study and other reports show that the accuracy of the technique is not 100 per cent. This begs the question of how much one can rely on the findings of such techniques when deciding whether second-look surgery is indicated. Scan-negative patients will require continued follow up as, at the time of imaging, residual disease may not have reached a detectable size.

IDEAL 3D spoiled gradient echo of the articular cartilage of the knee on 3.0 T MRI: a comparison with conventional 3.0 T fast spin-echo T2 fat saturation image

2014 ◽  
Vol 56 (12) ◽  
pp. 1479-1486 ◽  
Author(s):  
Chul Hee Han ◽  
Hee Jin Park ◽  
So Yeon Lee ◽  
Eun Chul Chung ◽  
Seon Hyeong Choi ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Gradient Echo ◽  
Fat Saturation ◽  
3.0 T ◽  
Fast Spin ◽  
3.0 T Mri ◽  
Spoiled Gradient Echo

Magnetic resonance imaging of hyaline cartilage defects at 1.5T and 3.0T: comparison of medium T2‐weighted fast spin echo, T1‐weighted two‐dimensional and three‐dimensional gradient echo pulse sequences

2005 ◽  
Vol 46 (1) ◽  
pp. 67-73 ◽  
Author(s):  
F. Fischbach ◽  
H. Bruhn ◽  
F. Unterhauser ◽  
J. Ricke ◽  
G. Wieners ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Hyaline Cartilage ◽  
Spin Echo ◽  
Three Dimensional ◽  
Fast Spin Echo ◽  
Two Dimensional ◽  
Gradient Echo ◽  
Lesion Detectability ◽  
Fast Spin ◽  
Field Strengths

Purpose: To evaluate and compare the diagnostic accuracy of appropriate magnetic resonance (MR) sequences in the detection of cartilage lesions at 1.5T and 3.0T. Material and Methods: Twelve chondral defects of varying depths, widths, and locations were created in the retropatellar hyaline cartilage in six sheep cadaver limbs. Axial images employing three fat‐suppressed imaging sequences – (1) a T2‐weighted fast spin‐echo (FSE) sequence, (2) a two‐dimensional (2D) and (3) three‐dimensional (3D) gradient‐echo (GE) sequence at 1.5T and 3.0T using an extremity quadrature coil – were evaluated by three experienced radiologists. Statistical analysis of the results consisted of receiver operating characteristics (ROC) and significant testing using the bivariate chi‐square test. In addition, signal‐to‐noise ratios (SNR) and contrast‐to‐noise ratios (CNR) were evaluated with significance testing using the Wilcoxon test. Results: The 3D GE sequence compared favorably with other sequences at 3.0T and 1.5T (Az = 0.88 at 3.0T and Az = 0.85 at 1.5T) missing only one small grade 2 lesion. 2D GE imaging was inferior to 3D imaging at both field strengths ( P<0.05) in general. However, compared to 1.5T, lesion detectability was improved at the higher magnetic field of 3.0T (Az = 0.81 and 0.73 at 3.0T and 1.5T, respectively). FSE images showed significantly inferior sensitivity and less anatomical detail compared to the GE sequences at both field strengths (Az = 0.64 and 0.72 at 3.0T and 1.5T, respectively; P<0.05). However, compared to 1.5T, lesion detectability SNR and CNR values were superior in all sequences tested at 3.0T. Conclusion: MRI at 3.0T improves SNR and CNR significantly in the most common sequences for cartilage MRI, resulting in an improvement in chondral lesion detection. GE imaging therefore allows resolution to be increased in an acceptable time manner for patient comfort, and the 3D GE fat‐suppressed sequence at 3.0T appears to be best suited for cartilage imaging in a clinical setting.

Ultra high resolution nonenhanced fast spin echo magnetic resonance imaging: Cost-effective screening for acoustic neuroma in patients with sudden sensorineural hearing loss

1998 ◽  
Vol 119 (4) ◽  
pp. 364-369 ◽  
Author(s):  
Robert L. Daniels ◽  
Clough Shelton ◽  
H. Ric Harnsberger
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hearing Loss ◽  
Magnetic Resonance ◽  
Sensorineural Hearing Loss ◽  
Acoustic Neuroma ◽  
Spin Echo ◽  
Sudden Sensorineural Hearing Loss ◽  
Fast Spin Echo ◽  
Resonance Imaging ◽  
Fast Spin

The financial burden for the evaluation of patients for acoustic neuroma in an otolaryngology practice is substantial. Patients with sudden sensorineural hearing loss represent a portion of that population seen with unilateral, asymmetric auditory symptoms who require investigation for acoustic neuroma. For these patients, gadolinium-enhanced magnetic resonance imaging is the diagnostic gold standard. Auditory brain stem response testing has been used in the past as a screening test for acoustic neuroma, but its apparent sensitivity has fallen as the ability to image smaller acoustic neuromas has improved. Fast spin echo magnetic resonance imaging techniques without gadolinium have been shown to be as effective in the detection of acoustic neuroma as contrast-enhanced magnetic resonance imaging. Limited nonenhanced fast spin echo magnetic resonance imaging now provides an inexpensive alternative for high-resolution imaging of the internal auditory canal and cerebellopontine angle. Fast spin echo magnetic resonance imaging can now be done at a cost approximating auditory brain stem response testing while providing the anatomic information of contrast-enhanced magnetic resonance imaging. Cost analysis was done in the cases of 58 patients with sudden sensorineural hearing loss by comparing the costs for routine workup and screening of acoustic neuroma with the cost of fast spin echo magnetic resonance imaging with the use of screening protocols based on literature review. The potential cost savings of evaluating patients with sudden sensorineural hearing loss with fast spin echo magnetic resonance imaging for acoustic neuroma was substantial, with a 54% reduction in screening costs. In an era of medical economic scrutiny, fast spin echo magnetic resonance imaging has become the most cost-effective method to screen suspected cases of acoustic tumors at our institution by improving existing technology while reducing the cost of providing that technology and eliminating charges for impedance audiometry, auditory brain stem response testing, and contrast-enhanced magnetic resonance imaging.

Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology

1996 ◽  
Vol 85 (2) ◽  
pp. 299-309 ◽  
Author(s):  
Aaron G. Filler ◽  
Michel Kliot ◽  
Franklyn A. Howe ◽  
Cecil E. Hayes ◽  
Dawn E. Saunders ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Time Course ◽  
Spin Echo ◽  
Fast Spin Echo ◽  
Mr Neurography ◽  
Magnetic Resonance Neurography ◽  
Cross Sectional ◽  
Content Type ◽  
Direct Nerve ◽  
Fine Print

✓ Currently, diagnosis and management of disorders involving nerves are generally undertaken without images of the nerves themselves. The authors evaluated whether direct nerve images obtained using the new technique of magnetic resonance (MR) neurography could be used to make clinically important diagnostic distinctions that cannot be readily accomplished using existing methods. The authors obtained T2-weighted fast spin—echo fat-suppressed (chemical shift selection or inversion recovery) and T1-weighted images with planes parallel or transverse to the long axis of nerves using standard or phased-array coils in healthy volunteers and referred patients in 242 sessions. Longitudinal and cross-sectional fascicular images readily distinguished perineural from intraneural masses, thus predicting both resectability and requirement for intraoperative electrophysiological monitoring. Fascicle pattern and longitudinal anatomy firmly identified nerves and thus improved the safety of image-guided procedures. In severe trauma, MR neurography identified nerve discontinuity at the fascicular level preoperatively, thus verifying the need for surgical repair. Direct images readily demonstrated increased diameter in injured nerves and showed the linear extent and time course of image hyperintensity associated with nerve injury. These findings confirm and precisely localize focal nerve compressions, thus avoiding some exploratory surgery and allowing for smaller targeted exposures when surgery is indicated. Direct nerve imaging can demonstrate nerve continuity, distinguish intraneural from perineural masses, and localize nerve compressions prior to surgical exploration. Magnetic resonance neurography can add clinically useful diagnostic information in many situations in which physical examinations, electrodiagnostic tests, and existing image techniques are inconclusive.

Sign in / Sign up

Export Citation Format

Share Document