Iron Utilization and Liver Mineral Concentrations in Rats Fed Safflower Oil, Flaxseed Oil, Olive Oil, or Beef Tallow in Combination with Different Concentrations of Dietary Iron

2004 ◽  
Vol 97 (3) ◽  
pp. 265-278 ◽  
Author(s):  
Andrea D. Shotton ◽  
Elizabeth A. Droke
2003 ◽  
Vol 284 (1) ◽  
pp. E18-E24 ◽  
Author(s):  
Carine Beysen ◽  
Abigail K. Belcher ◽  
Fredrik Karpe ◽  
Barbara A. Fielding ◽  
Emilio Herrera ◽  
...  

This study reports a novel protocol to increase plasma monounsaturated, polyunsaturated, and saturated nonesterified fatty acids (NEFA) in eight healthy volunteers (age 29–54 yr, body mass index 23–26 kg/m2). This was achieved by feeding small boluses of fat at different time points (35 g at 0 min and 8 g at 30, 60, 90, 120, 150, 180, and 210 min) in combination with a continuous low-dose heparin infusion. Olive oil, safflower oil, or palm stearin were used to increase monounsaturated, polyunsaturated, or saturated NEFAs, respectively. Plasma NEFA concentrations were increased for 2 h, when fat and heparin were given (olive oil: 745 ± 35 μmol/l; safflower oil: 609 ± 37 μmol/l, and palm stearin: 773 ± 38 μmol/l) compared with the control test (no fat and no heparin: 445 ± 41 μmol/l). During the heparin infusion, 18:1 n-9 was the most abundant fatty acid for the olive oil test compared with 18:2 n-6 for the safflower oil test and 16:0 for the palm stearin test ( P < 0.01). The method described here successfully increases several types of plasma NEFA concentrations and could be used to investigate differential effects of elevated individual NEFAs on metabolic processes.


2006 ◽  
Vol 13 (1) ◽  
pp. 35-37
Author(s):  
Kothapa N. Chetty ◽  
LeShanna Calahan ◽  
Robert OliverIII ◽  
Srikrishna N. Chetty

2014 ◽  
Vol 220 (3) ◽  
pp. 345-359 ◽  
Author(s):  
M Kurtz ◽  
E Capobianco ◽  
V Careaga ◽  
N Martinez ◽  
M B Mazzucco ◽  
...  

Maternal diabetes impairs fetal lung development. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors relevant in lipid homeostasis and lung development. This study aims to evaluate the effect ofin vivoactivation of PPARs on lipid homeostasis in fetal lungs of diabetic rats. To this end, we studied lipid concentrations, expression of lipid metabolizing enzymes and fatty acid composition in fetal lungs of control and diabetic rats i) after injections of the fetuses with Leukotriene B4(LTB4, PPARα ligand) or 15deoxyΔ12,14prostaglandin J2(15dPGJ2, PPARγ ligand) and ii) fed during pregnancy with 6% olive oil- or 6% safflower oil-supplemented diets, enriched with PPAR ligands were studied. Maternal diabetes increased triglyceride concentrations and decreased expression of lipid-oxidizing enzymes in fetal lungs of diabetic rats, an expression further decreased by LTB4and partially restored by 15dPGJ2in lungs of male fetuses in the diabetic group. In lungs of female fetuses in the diabetic group, maternal diets enriched with olive oil increased triglyceride concentrations and fatty acid synthase expression, while those enriched with safflower oil increased triglyceride concentrations and fatty acid transporter expression. Both olive oil- and safflower oil-supplemented diets decreased cholesterol and cholesteryl ester concentrations and increased the expression of the reverse cholesterol transporter ATP-binding cassette A1 in fetal lungs of female fetuses of diabetic rats. In fetal lungs of control and diabetic rats, the proportion of polyunsaturated fatty acids increased with the maternal diets enriched with olive and safflower oils. Our results revealed important changes in lipid metabolism in fetal lungs of diabetic rats, and in the ability of PPAR ligands to modulate the composition of lipid species relevant in the lung during the perinatal period.


1990 ◽  
Vol 120 (11) ◽  
pp. 1291-1296 ◽  
Author(s):  
Yoshiharu Shimomura ◽  
Tomohiro Tamura ◽  
Masashige Suzuki

1992 ◽  
Vol 43 (2) ◽  
pp. 389 ◽  
Author(s):  
PF Mannion ◽  
AR Neill ◽  
M Brewster

The relationships between dietary fat content and dietary fatty acid composition and egg weight were investigated in two strains of laying hens. Six diets were fed in which the levels of readily absorbable fatty acids, including linoleic acid, were increased by the addition of up to 32.6 g kg-1 safflower oil. Two additional diets containing olive oil provided intermediate or high levels of readily absorbable fatty acids and a low level of linoleic acid. The diets were fed from 30 to 46 weeks of age (phase 1) and again from 54 to 70 weeks of age (phase 2) after an intermediate buffer period in which a diet low in both fat and linoleic acid was fed. The diets had no significant effect on feed intake, liveweight or egg mass output, although small differences in egg number occurred. Egg weight responded to increasing levels of safflower oil in the diet but not to similar levels of olive oil. These differences cannot be attributed to dietary energy or to the intake of nutrients other than those associated with the inclusion of vegetable oil. It is concluded that the linoleic acid component of safflower oil is responsible for the observed effects on egg weight. As judged by regression analyses the egg weight response was significant in only one strain, being linear in phase 1 and curvilinear in phase 2.


2010 ◽  
Vol 79 (9) ◽  
pp. S21-S28 ◽  
Author(s):  
Tereza Krejčí-Treu ◽  
Eva Straková ◽  
Pavel Suchý ◽  
Ivan Herzig

The main objective of this work was to compare the effect of six vegetable oils added to feeding mixtures that were administered to broiler chickens on the content of major fatty acids in chicken meat. The experiment started with 90 one-day-old Ross 308 meat hybrid male chickens that were divided into six groups. Chickens were fed complete feeding mixtures for the prefattening (BR1), fattening (BR2), and post-fattening (BR3) of broiler chickens. The BR1 feeding mixture was administered to chickens aged 1-10 days, the BR2 feeding mixture was given from Day 11 to Day 30, and the BR3 feeding mixture was then administered until Day 42. The BR1 feeding mixture that was administered to all six groups during the first ten days of the experiment was supplemented with soybean oil. BR2 and BR3 feeding mixtures used to feed chickens aged 11-42 days were fortified with soybean oil (SO Group), rapeseed oil (RO Group), sunflower oil (SFO Group), flaxseed oil (FO Group), olive oil (OO Group), and evening primrose oil (EPO Group). The vegetable oils used differed by the composition of fatty acids, particularly by the content of oleic acid, linoleic acid, α-linolenic acid. The use of the above-described experimental diets in young broilers from Day 11 to 42 had a significant effect on the content of fatty acids in the fat from breast and thigh muscles. The content of α-linolenic acid in breast and thigh muscles of broilers that received the feed containing flaxseed oil (21.16 g/100 g of oil and 17.13 g/100 g of oil, respectively) significantly increased (p ⪬ 0.01). The highest content of linoleic acid (p ⪬ 0.01) in breast and thigh muscles was found in chickens that were fed the feed containing primrose oil (59.13 g/100 g and 51.71 g/100 g). A significant increase (p ⪬ 0.01) in the level of oleic acid was detected in both breast and thigh muscles of broilers that received olive oil fortified feed (52.44 g/100 g and 43.70 g/100 g of oil). No significant variation was found in the content of palmitic acid and palmitooleic acid. The levels of oleic acid, linoleic acid and α-linolenic acid in feeding mixtures correlated with those found in breast and thigh muscles (r = 0.88; 0.94 and 0.99; r = 0.99; 0.98 and 0.99).


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