Molecular Mechanism of Scorpion Neurotoxins Acting on Sodium Channels: Insight Into Their Diverse Selectivity

2004 ◽  
Vol 30 (3) ◽  
pp. 265-278 ◽  
Author(s):  
Xiao-Pan Zuo ◽  
Yong-Hua Ji
Keyword(s):  
Molecular Mechanism ◽  
Sodium Channels ◽  
Insight Into

Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro

2015 ◽  
Vol 173 ◽  
pp. 91-99 ◽  
Author(s):  
Yi-min Ma ◽  
Xin-zhuang Zhang ◽  
Zhen-zhen Su ◽  
Na Li ◽  
Liang Cao ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Network Pharmacology ◽  
Insight Into

Quantitative proteomic analysis of global effect of LLL12 on U87 cell's proteome: An insight into the molecular mechanism of LLL12

2015 ◽  
Vol 113 ◽  
pp. 127-142 ◽  
Author(s):  
Rekha Jain ◽  
Prajakta Kulkarni ◽  
Snigdha Dhali ◽  
Srikanth Rapole ◽  
Sanjeeva Srivastava
Keyword(s):  
Molecular Mechanism ◽  
Proteomic Analysis ◽  
Global Effect ◽  
Quantitative Proteomic Analysis ◽  
Insight Into

scholarly journals Insight into the molecular mechanism of the multitasking kinesin-8 motor

2010 ◽  
Vol 29 (20) ◽  
pp. 3437-3447 ◽  
Author(s):  
Carsten Peters ◽  
Katjuša Brejc ◽  
Lisa Belmont ◽  
Andrew J Bodey ◽  
Yan Lee ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Insight Into

New insight into lignin aggregation guiding efficient synthesis and functionalization of a lignin nanosphere with excellent performance

2021 ◽  
Author(s):  
Liheng Chen ◽  
Si-Man Luo ◽  
Cong-Min Huo ◽  
Yun-Feng Shi ◽  
Jun Feng ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Efficient Synthesis ◽  
Excellent Performance ◽  
Biomass Valorization ◽  
Insight Into

Understanding the molecular mechanism of lignin nanoparticle (LNP) formation will precisely instruct its functionalization, which is of importance for biomass valorization.

Microbially Originated Polyhydroxyalkanoate (PHA) Biopolymers: An Insight into the Molecular Mechanism and Biogenesis of PHA Granules

2018 ◽  
pp. 355-398 ◽  
Author(s):  
Akhilesh Kumar Singh ◽  
Laxuman Sharma ◽  
Janmejai Kumar Srivastava ◽  
Nirupama Mallick ◽  
Mohammad Israil Ansari
Keyword(s):  
Molecular Mechanism ◽  
Insight Into

Intrinsic gating mechanisms of epithelial sodium channels

2002 ◽  
Vol 283 (2) ◽  
pp. C646-C650 ◽  
Author(s):  
Hong-Long Ji ◽  
Catherine M. Fuller ◽  
Dale J. Benos
Keyword(s):  
Sodium Channels ◽  
Xenopus Oocytes ◽  
Transmembrane Domain ◽  
Receptor Site ◽  
Epithelial Sodium Channels ◽  
Gating Mechanisms ◽  
Putative Receptor ◽  
Arginine Residues ◽  
Insight Into ◽  
Positively Charged

The hypothesis that there is a highly conserved, positively charged region distal to the second transmembrane domain in α-ENaC (epithelial sodium channel) that acts as a putative receptor site for the negatively charged COOH-terminal β- and γ-ENaC tails was tested in mutagenesis experiments. After expression in Xenopus oocytes, α-ENaC constructs in which positively charged arginine residues were converted into negatively charged glutamic acids could not be inhibited by blocking peptides. These observations provide insight into the gating machinery of ENaC.

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