scholarly journals Domperidone and maternal milk volume in mothers of premature newborns

2017 ◽  
Vol 57 (1) ◽  
pp. 18 ◽  
Author(s):  
Tengku Ellya Fazilla ◽  
Guslihan Dasa Tjipta ◽  
Muhammad Ali ◽  
Pertin Sianturi

Background Mothers of premature newborns often have difficulty giving adequate breast milk volume to their infants. Domperidone is an antagonist of peripheral dopamine receptors and believed to increase breast milk production. In Indonesia, no study has been done to date on the effect of domperidone on maternal milk production in mothers of premature newborns.  Objective To evaluate the effect of domperidone on milk production in mothers of premature newborns who failed to lactate.Methods A randomized controlled trial was conducted from July to December 2012 in the Perinatology Unit, Haji Adam Malik Hospital, Medan. Mothers of premature newborns were given lactation counseling for 7 days in order to increase their milk production. Mothers who failed to lactate after that time were enrolled in the study. Fifty subjects were assigned to receive either domperidone or a placebo for 7 days. Milk volume was measured every 2 hours (from 7 am to 9 pm), in the 24 hours before starting therapy, and on the 7th and 10th days (the 10th day being 3 days after stopping therapy). Results This study involved 25 mothers in the domperidone groups and 25 others in placebo group. After 7 days of therapy, mean breast milk volume was significantly higher in the domperidone group than in the placebo group  [181.6 (SD 80.2) vs. 72.4 (SD 57.8) mL, respectively; 95%CI of differences 69.36 to 148.93; P=0.0001]. At day 10, breast milk production remained significantly higher in the domperidone group. Furthermore, in the domperidone group, no significant difference in mean breast milk volumes was noted between the 7th and 10th days (P=0.65). Conclusion In mothers of premature newborns who failed to lactate, domperidone therapy for 7 days causes significantly higher milk production compared to placebo. 

2020 ◽  
Vol 8 (4) ◽  
pp. 416
Author(s):  
Anita Liliana ◽  
Melania Wahyuningsih

Abstract Adequacy of milk production in the newborns will affect the success of exclusive breastfeeding. Not all postpartum mothers are able to increase milk production in the postpartum period. Acupressure at the meridian points is one way to increase milk production in postpartum mothers. This study aims to determine the effect of acupressure therapy on increasing breast milk production in postpartum mothers at PKU Muhamadiyah Bantul. This study was a quantitative study  a quasi-experimental research design with pre-test and post-test nonequivalent control group. The number of respondents in each group was 17 people. The treatment given was acupressure at the meridian points for 5 minutes on days 2 and 3of poatpartum. Breastfeeding adequacy was assessed before treatment and on day 4 postpartum. Data were analyzed by Mc Nemar analysis. The results showed that there was a significant difference in breast milk production before and after acupressure with p value of 0.000 (p value <0.05). There was a significant difference in breast milk production in the control group before and after being given the breastfeeding technique leaflet p value 0.001 (p value <0.05). Conclusion: There is no significant difference in breast milk production after being given acupressure and after being given leaflets about breastfeeding techniques at PKU Muhamadiyah Bantul p value 0.100 (p value> 0.05).  Keywords: acupressure, breast milk production, postpartum


2017 ◽  
Vol 9 (02) ◽  
pp. 1
Author(s):  
Adinda Putri Sari Dewi ◽  
Djaswadi Dasuki ◽  
Farida Kartini

Penelitian ini bertujuan untuk Mengetahui efek pijat punggung sebagai salah satu cara dalam meningkatkan produksi ASI pada ibu pasca bedah sesar. Desain Penelitian yang digunakan adalah Randomized Controlled Trial. Teknik Pengambilan sampel dengan simple random sampling dengan jumlah sampel sebanyak 27 responden pada masing-masing kelompok (intervensi dan kontrol). Analisis bivariat menggunakan chi square dengan tingkat kemaknaan p<0,05, analisis multivariat menggunakan regresi logistik untuk mengidentifikasi variabel perancu terhadap produksi ASI pasca bedah sesar. Hasil Penelitian menunjukan adanya perbedaan produksi ASI antara kelompok intervensi dan kelompok kontrol dengan RR sebesar 1,9 (95%CI: 1,097-3,291). Paritas dan frekuensi menyusui mempunyai hubungan yang bermakna dengan produksi ASI pada ibu pasca bedah sesar.Usia ibu, obesitas, waktu rawat gabung tidak memiliki hubungan yang bermakna dengan produksi ASI.


2020 ◽  
Vol 5 (1) ◽  
pp. 51
Author(s):  
Nursari Abdul Syukur ◽  
Endah Wahyutri ◽  
Erma Putri

Background: Breast milk spending is a very complex interaction between mechanics, nerves, and hormons. The decrease and production of breast milk production in the first days after delivery can be caused by a lack of stimulation of prolactin and oxytocin hormons. Caesarea section does not allow the mother to breastfeed her infant more flexibly, with adaptation to the pain, so she should be able to support the health worker thoroughly about the lactation process. Purpose: to know the difference of endorphin, oxytocin and combination effect on breast milk production in Postoperative section of caesarea section. Research design: quasi experimental design type post test only non equivalent control group design. The population in this study were all postoperative mothers caesarea section, 10 samples for each treatment. Group 1 : endorphin massage, group 2 (control) : the oxytocin massage, and group 3 : the combine massage. Results: Combination massage is the best method to produce the highest amount of ASI because the largest Sig p value is (1,000) where the level is significant <0.05. So H0 this study was rejected means that there is a significant difference between the production of breast milk from the combination massage compared with the two massage done separately. Conclusion: It is expected during childbirth the midwife can develop and implement independent non-pharmacological midwife actions to help increase milk production


2017 ◽  
Vol 3 (2) ◽  
pp. 95-101
Author(s):  
Ima Candra Kusuma ◽  
Onny Setiani ◽  
Umaroh Umaroh ◽  
Noor Pramono ◽  
Melyana Nurul Widyawati ◽  
...  

Background: Sweet potato leaf is assumed to be one of alternative herbs that can increase breast milk production. However, there was no studies found in the literature that examine the sweet potato leaves to increase the levels of prolactin and milk production.Objective: To examine the effect of sweet potato (Ipomoea batatas L.) leaf on the levels of prolactin and milk production in postpartum mothers.Methods: This was a Quasy experimental study with pretest-posttest design with control group, conducted on November 2016 to December 2016 in the Health Center (Puskesmas) of Boyolali I. Thirty respondents were selected using consecutive sampling, which were divided to be 15 respodents in intervention group and 15 respondents in control group. Enzyme-linked immunosobent assay (ELISA) was used to measure prolactin levels, while breast milk production was measured based on the volume of breast milk and baby’s weight. Data were analzed using Independent t-test and paired t-test.Results: Finding showed that there was a significant difference in prolactin levels between the intervention (270.43) and control group (156.28) after intervention  with p-value 0.000, and a significant difference in breast milk production in terms of breast milk volume (intervention group 136.33; and control group 119) with p-value 0.028; and baby’s weight (intervention group 3030.3; and control group 2787.33) with p-value 0.000.Conclusion: There was  a significant effect of sweet potato (Ipomoea batatas L.) leaf on the levels of prolactin and breast milk production. Thus, it could be suggested that sweet potato leaves should be considered to be one of alternative treatements for health care providers, especially for midwives to help breastfeeding mothers in increasing their breast milk production and prolactin levels. Further research is needed to examine all factors affecting breast milk production.


1981 ◽  
Vol 45 (2) ◽  
pp. 243-249 ◽  
Author(s):  
S. Rattigan ◽  
Ann V. Ghisalberti ◽  
P. E. Hartmann

1. Milk productions and 7d dietary records were determined on twenty-seven mothers who had been breast-feeding for 1, 3, 6, 9, 12 and 15 months.2. The mean milk productions for each group of mothers was 1.187, 1.238, 1.128, 0.884, 0.880 and 0.951 kg/24 h at 1, 3, 6, 9, 12 or 15 months of lactation respectively. There was no significant difference between two milk determinations 3–7 d apart on each mother or between the mean milk production of each group of mothers.3. Energy intakes of the infants was found to be higher than the usually-accepted values at 1 and 3 months of age but by 6 months were similar to the accepted normal values.4. Energy intakes of the mothers although greater than those recommended for similar non-lactating women were not sufficient to take into account the energy content of the milk.


Author(s):  
Prita Alvina Reviana ◽  
◽  
Yulia Lanti Retno Dewi ◽  
Vitri Widyaningsih ◽  
◽  
...  

ABSTRACT Background: Goat milk has some potential nutrition than cow milk. Studies suggested that goat milk is better digested and absorbed than cow milk. It also has less allergen protein and lower lactose. Previous studies examined the benefit of goat milk as infant feeding to increase infant growth compared with cow milk-based formula. However, the studies that analyze the effect of goat milk in increasing breast milk production are scarce. This study aimed to examine the effectiveness of goat milk to increase breast milk volume in lactating mothers. Subjects and Method: This was a randomized controlled trial (RCT). The study was conducted in Madiun, East Java, in October 2019. A sample of 100 lactating mothers with children aged 1 to 3 months was selected purposively. The dependent variable was volume of breast milk. The independent variable was the effectiveness of goat milk. The data were collected by food recall 24 hours and observational sheet. The data were analyzed by t test. Results: Breast milk production after giving goat milk in the intervention group (Mean= 121.5; SD= 12.81) was higher than control group (Mean= 97.06; SD= 13.59), and it was statistically significant (p<0.001). Conclusion: Goat milk is effective to increase quantity of breast milk in lactating mothers. Keywords: breast milk production, goat milk Correspondence: Prita Alvina Reviana. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: [email protected]. Mobile: +6282334673976 DOI: https://doi.org/10.26911/the7thicph.05.38


2010 ◽  
Vol 13 (2) ◽  
pp. 162 ◽  
Author(s):  
Antonio Alberto Zuppa ◽  
Paola Sindico ◽  
Claudia Orchi ◽  
Chiara Carducci ◽  
Valentina Cardiello ◽  
...  

Poor production of breast milk is the most frequent cause of breast lactation failure. Often, physician prescribe medications or other substances to solve this problem. The use of galactogogues should be limited to those situations in which reduced milk production from treatable causes has been excluded. One of the most frequent indication for the use of galactogogues is the diminution of milk production in mothers using indirect lactation, particularly in the case of preterm birth. The objective of this review is to analyze to the literature relating to the principal drugs used as galactogogues (metoclopramide, domperidone, chlorpromazine, sulpiride, oxytocin, growth hormone, thyrotrophin releasing hormone, medroxyprogesterone). Have been also analyzed galactogogues based on herbs and other natural substances (fenugreek, galega and milk thistle). We have evaluated their mechanism of action, transfer to maternal milk, effectiveness and potential side effects for mother and infant, suggested doses for galactogogic effect, and recommendation for breastfeeding.


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