scholarly journals Profile of Aerobic Bacteria in Surgical Site Infection Following Caesarean Section and Antibiotic Susceptibility Pattern in Silchar Medical College, India

2021 ◽  
Vol 10 (35) ◽  
pp. 3030-3034
Author(s):  
Nazrana Choudhury ◽  
Abul Barkat Fuzayel Ahmed ◽  
Debadatta Dhar Chanda ◽  
Achinta Kumar Borthakur
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Caesarean Section ◽  
Surgical Site Infection ◽  
Site Infection ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Medical College ◽  
Antimicrobial Susceptibility Pattern

BACKGROUND Caesarean section is one of the most common surgeries performed in women of reproductive age group. Postoperative surgical site infection (SSI) is the third most frequently reported nosocomial infection. Recovery after caesarean section can be more demanding for a woman who develops a post-operative surgical site infection that can even lead to death. Surveillance of surgical site infection is an important infection control activity. A better understanding of the spectrum of pathogens causing SSI as well as their susceptibility pattern is important for prompt management of patients. The main objectives of this study were to identify the bacterial agents causing postoperative wound infection in caesarean section, as well as determine the in-vitro antimicrobial susceptibility pattern of different bacterial isolates and also to examine the risk factors of postoperative caesarean infection. METHODS This is an observational (cross sectional study) where 100 cases of postoperative caesarean section wound infection admitted in the Department of Obstetrics & Gynaecology ̦ Silchar Medical College were studied. Pus samples were collected and cultured, and the pathogenic isolates were tested against different antimicrobial agents by standard disc diffusion method (Kirby-Bauer method) as per the recommendation of Clinical and Laboratory Standard Institute (CLSI) guidelines. RESULTS The study revealed Staphylococcus aureus 38.1 % of which 21.9 % were methicillin resistant (MRSA), as the most common organism responsible for SSI followed by Escherichia coli 23.8 % and Klebsiella pneumoniae 16.7 %. Staphylococcus aureus was 100 % sensitive to vancomycin and linezolid 78.1 % and 71.9 % sensitive to erythromycin and ciprofloxacin respectively. The most sensitive antimicrobials for Gram negative isolates were polymyxin B 96.2 %, imipenem 94.2 % and ciprofloxacin 76.9 %. Emergency C-section (83 %), premature rupture of membranes (PROM) 30 %, prolong labour 26 %, history of previous caesarean section 22 %, anaemia 15 % cases and BMI ≥ 25 (16 %) were found to be risk factors. CONCLUSIONS The findings of preponderance of Staphylococcus aureus and Gram negative bacilli in this study with good antibiotic sensitivity against the fluoroquinolone and aminoglycosides is of local clinical relevance. KEY WORDS Caesarean Section, Surgical Site Infection, Antimicrobial Susceptibility Pattern, Bacterial Isolates, MRSA Strains

scholarly journals Isolation of Aerobic Bacteria from Surgical Site Infection and their Antibiotic Susceptibility Pattern

2017 ◽  
Vol 2 (2) ◽  
pp. 28-32
Author(s):  
Shahin Ara Begum ◽  
Shabeen Afreen ◽  
Aliya Rashid ◽  
Nasreen Farhana
Keyword(s):  
Staphylococcus Aureus ◽  
Surgical Site Infection ◽  
Antibiotic Susceptibility ◽  
Aerobic Bacteria ◽  
Site Infection ◽  
Susceptibility Pattern ◽  
Antibiotic Susceptibility Pattern ◽  
Gram Negative ◽  
Causative Agents ◽  
Gram Positive Cocci

Background: Surgical site infection is one of the commonest complications after surgical intervention. Source of wound infections may be exogenous or endogenous. Wound swabs culture is the most frequently used method for confirming the diagnosis of surgical site infection. A regular bacteriological review is necessary to identify the causative agents and their antibiotic susceptibility pattern.Objective: The purpose of the present study was to find out the aerobic bacteria from wound swabs culture and their antibiotic susceptibility pattern.Methodology: A total of 175 wound swabs sample were collected aseptically from surgical site infection during the study period. Standard bacteriological methods were used for isolation and identification of organisms and their susceptibility pattern.Results: A total of 175 wound swab samples were collected from surgery departments. Out of 175 samples 102 (58.28%) were positive by culture. Among the isolated organisms the gram negative bacilli were predominant 67 (65.68%) than the gram positive cocci 35 (34.32%).The most common isolated bacteria were Escherichia.coli 30(29.41%) followed by Staphylococcus aureus 28 (27.45%) Pseudomonous areuginosa 20(29.85%), Acinetobacter spp 08(11.94%), Coaggulase negative Staphylococcus (CONS) 07(6.86%) Klebsiella pneumoniae 05(4.90%), Proteus spp 03(4.45%), and Citobacter spp 01(1.49%). Among the total 175 samples 114(65.14%) were collected from male patients and 61(34.86%) were from female patients. All the isolated gram negative bacilli showed resistant to all antibiotics and all isolated gram positive cocci were resistant to all antibiotics except Linezolid. Among the isolated Staphylococcus aureus 8 (24.85%) were MRSA and one (3.57%) were VRSA. The most effective antibiotics were Amikacin, Meropenem, Imipenem and Tazobactam in this study.Conclusion: Surgical site infections remain the commonest post operative complications after surgery and one of the commonest encountered hospital acquired infections. Therefore, periodic review needs be done to find out the causative agents and their antibiotic susceptibility pattern for better treatment and managementBangladesh Journal of Infectious Disease 2015;2(2):28-32

scholarly journals Incidence, risk factors and Microorganisms for post caesarean Surgical Site Infection In A Tertiary Care Centre in Bangladesh

2021 ◽  
Vol 28 (2) ◽  
pp. 136-141
Author(s):  
Shahfinaz Mehzabin ◽  
Mohmmad Mahbub Elahi ◽  
Debashish Bar ◽  
Banalata Sinha ◽  
Tahmina Akter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Caesarean Section ◽  
Surgical Site Infection ◽  
Surgical Site Infections ◽  
Site Infection ◽  
Medical College ◽  
Related Risk ◽  
Microbiological Methods ◽  
Duration Of Surgery ◽  
History Of

Background: Surgical site infection (SSI) is a common complication following caesarean section (C-section) and mainly responsible for increased maternal morbidity and higher treatment costs. This study will determine the incidence and risk factors of surgical site infections following caesarean section in Dhaka Medical College Hospital (DMCH). Materials and Methods: This is a retrospective observational study which was conducted among patients having post caesarean surgical site infections attending post-natal outdoor clinic of DMCH from January, 2019 to December, 2019. Data were collected in structured questionnaire. Culturebased microbiological methods were used to identify causal agents in postoperative wounds. Results: Overall SSI rate following caesarian section was 4.44%.Patient related risk factors were inadequate antenatal check-up, emergency procedures, malnutrition (22.44%), anaemia (21.46%) associated comorbidity (59.46%), history of rupture membrane >12 hours (40.98%) and had history of prolonged labour pain >12 hours (16.10%).Surgery related risk factors were repeated per vaginal examinations by untrained birth attendant (21.95%) & duration of surgery>1 hour (62.93%). The most common organisms responsible for SSI were Staphylococcus aureus 44(21.46%) and Escherichia coli 31(15.12%). The most sensitive antibiotics were aminoglycosides, cephalosporin & cloxacillin. Conclusion: Most of the risk factors for surgical site infection following caesarean section identified in this study can be modified through intervention. However the microorganisms detected from our patient showed a high degree of resistance for commonly prescribed antimicrobials in our set-up. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 136-141

scholarly journals Study on Risk Factors and Microorganisms for Surgical Site Infection following Caesarean Section among 100 Patients in a Tertiary Hospital in Bangladesh

2019 ◽  
Vol 9 (2) ◽  
pp. 90-96
Author(s):  
Sayma Afroz ◽  
Maliha Rashid
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Caesarean Section ◽  
Surgical Site Infection ◽  
Mode Of Delivery ◽  
Operation Time ◽  
Site Infection ◽  
College Hospital ◽  
Bacteriological Study ◽  
E Coli

Background: Lower uterine caesarean section is a common mode of delivery now and surgical site infection is one of the most common and dreaded complication of surgery. It is associated with significant morbidity and delayed recovery and it lengthens hospital stay and costs. Identifying risk factors for surgical site infection in caesarean wound and modifying them can be beneficial for patient management during surgery and optimizing good clinical outcome. Identifying microorganisms with their sensitivity has epidemiological as well as therapeutic implications. Objective: To identify risk factors for surgical site infection in caesarean section wound and find out microorganisms responsible for such infection. Materials and Methods: In this study 100 women with surgical site infection after caesarean section were included. They were selected randomly from four maternity units of Dhaka Medical College Hospital. Each patient of caesarean section was followed strictly up to discharge from hospital and also for 30 days postoperatively for any evidence of infection. Wound swab was sent in each case for microbiological study. Data were collected in structured questionnaire and analysed by computer using spreadsheet. Results: Among 100 women studied, 73% had inadequate or no antenatal check-up, 52% had duration of labour pain >12 hours, 52% had duration of ruptured membrane >12 hours, 94% women underwent emergency caesarean section, 62% had operation time >1 hour, 61% had haemoglobin level <60%, 46% women had intervention by untrained birth attendant, and 43% women had >500 mL blood loss during operation. In bacteriological study, microorganisms were identified in 55% cases, among them Staphylococcus aureus (20%), E. coli (11%), Acinetobacter (7%), Pseudomonas (6%) and Proteus (5%). During sensitivity test Staphylococcus aureus was mostly sensitive to ceftriaxone (50%) and amikacin (33%) and E. coli to amikacin (80%). In four cases (2 proteus and 2 pseudomonas) out of 55 organisms were resistant to all antibiotics. Conclusion: Most of the risk factors for surgical site infection during caesarean section identified in this study can be modified through intervention. However, the microorganisms detected from our patients showed a high degree of resistance for commonly prescribed antimicrobials in our set-up. J Enam Med Col 2019; 9(2): 90-96

scholarly journals Assessment of risk factors for surgical site infection following caesarean section

2019 ◽  
Vol 8 (11) ◽  
pp. 4518
Author(s):  
Aditi Sangwan ◽  
Vani Malhotra
Keyword(s):  
Risk Factors ◽  
Caesarean Section ◽  
Surgical Site Infection ◽  
Site Infection ◽  
Emergency Caesarean ◽  
Group I ◽  
Number Of Patients ◽  
Duration Of Surgery ◽  
Wound Discharge ◽  
Group Ii

Background: Assessment of surgical site infection is an important factor to determine the functioning of the health care system. Objectives of this study was to estimate the incidence of surgical site infection among caesarean section cases and to determine the risk factors associated with surgical site infection and comparison with patients having healthy wounds.Methods: One thousand pregnant women who underwent caesarean section were divided into two groups: Group 1 (cases): Those who had SSI within 30 days of caesarean section and Group 2 (controls): Those who didn’t have SSI.Results: Mean age of group I was 25.35±4.40 and 21.12±3.60 years in group II (p >0.05). Mean gestational age of group I cases was 38.07±1.88 weeks and in group II, it was 38.17±2.06 weeks (p >0.05). A total of 37 (82.5%) women in group I and 931 (96.98%) women in group II underwent emergency caesarean section (p <0.05). In group I, mean duration of surgery was 1.0±0.13 hours and 1.02±0.21 hours in group II (p <0.05). Maximum number of patients i.e. 22 (55%) had wound discharge between 4-7 days followed by 11 (27.5%) between 8-10 days. Mean wound discharge was 7.32±3.45 days in group I. Majority of women, i.e. 27 (67%) found to be sterile in the present study followed by 7 (17.5%) women were found to have staphylococcus aureus.      Mean duration of resuturing was 17.42±6.98 days.  Mean baby weight in group I was 2.72±0.53 kg and in group II it was 2.95±0.53 kg (p <0.001).Conclusions: Risk of developing SSI after caesarean section is multi-factorial and found to be influenced by emergency surgery, PROM, pre-operative anaemia, multiple vaginal examinations, interrupted skin suturing, raised BMI, nulliparity, emergency caesarean, duration of surgery.

scholarly journals Incidence and risk factors for surgical site infection following elective foot and ankle surgery: a retrospective study

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jinghong Meng ◽  
Yanbin Zhu ◽  
Yansen Li ◽  
Tao Sun ◽  
Fengqi Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Retrospective Study ◽  
Surgical Site Infection ◽  
Elective Surgery ◽  
Site Infection ◽  
Foot And Ankle ◽  
Coagulase Negative Staphylococci ◽  
Methicillin Resistant ◽  
Associated Risk Factors

Abstract Background This study aimed to investigate the incidence of surgical site infection (SSI) in elective foot and ankle surgeries and identify the associated risk factors. Methods This was designed as a retrospective study, including patients who underwent elective surgery of foot and ankle between July 2015 and June 2018. Data on demographics, comorbidities, and perioperative parameters were collected from the medical records, the laboratory report, the operation report, and the outpatient follow-up registration database. SSI was defined in accordance with the Center for Disease Control criteria. Univariate and multivariate logistic regression analyses were used to identify the independent risk factors for SSI. Results A total of 1201 patients undergoing 1259 elective foot/ankle surgeries were included, of whom 26 (2.1%) had an SSI, representing an incidence rate of 1.3% for superficial SSI and 0.8% for deep SSI, respectively. The results for organism culture showed Pseudomonas aeruginosa in 7 cases, methicillin-resistant Staphylococcus aureus (MRSA) in 6, methicillin-susceptible Staphylococcus aureus (MSSA) in 5, methicillin-resistant coagulase-negative Staphylococci (MRCNS) in 2, Escherichia coli in 2, and Proteus mirabilis in 1 case. Five factors were identified to be independently associated with SSI, including prolonged preoperative stay (OR, 1.21; 95% CI, 1.09 to 1.30), allograft or bone substitute (OR, 3.76; 95% CI, 1.51 to 5.30), elevated FBG level (OR, 1.17; 95% CI, 1.04 to 1.26), lower ALB level (OR, 2.33; 95% CI, 1.19 to 3.05), and abnormal NEUT count (OR, 1.72; 95% CI, 1.27 to 2.12). Conclusions SSI following elective foot and ankle surgeries is low, but relatively high in forefoot surgeries, requiring particular attention in clinical practice. Although most not modifiable, these identified factors aid in risk assessment of SSI and accordingly stratifying patients and therefore should be kept in mind.

Risk factors for surgical site infection following caesarean section in England

2013 ◽  
Vol 120 (4) ◽  
pp. 509-510 ◽  
Author(s):  
C Wloch ◽  
J Wilson ◽  
T Lamagni ◽  
P Harrington ◽  
A Charlett ◽  
...  
Keyword(s):  
Risk Factors ◽  
Caesarean Section ◽  
Surgical Site Infection ◽  
Site Infection

scholarly journals Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot Comprehensive and Specialized Hospital, Northwest Ethiopia. A prospective study

2020 ◽  
Author(s):  
Adugna Fenta ◽  
Mulat Dagnew ◽  
Setegn Eshetie ◽  
Teshome Belachew
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antimicrobial Susceptibility ◽  
Northwest Ethiopia ◽  
Bacterial Isolates ◽  
Susceptibility Pattern ◽  
Gram Negative ◽  
Antimicrobial Susceptibility Pattern ◽  
Specialized Hospital

Abstract Background: Urinary tract infection is one of the most common bacterial infections in children. Understanding the characteristics of uropathogens and their antimicrobial susceptibility pattern in a particular setting can provide evidence for the appropriate management of cases. This study aimed to assess the bacterial profile of urinary tract infection, their antimicrobial susceptibility pattern and associated factors among clinically suspected children attending at Felege-Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia.Methods: A hospital-based cross-sectional study was conducted from February-April, 2019. A systematic sampling technique was employed. A mid-stream urine sample was inoculated on cystine lactose electrolyte deficient media and incubated for 24-48 hours. Sub-culturing was done on Mac-Conkey and blood agar. Antimicrobial susceptibility test was done on Muller-Hinton agar. A binary logistic regression model was used to see the association between dependent and independent factors. A p-value<0.05 at 95% CI was considered as statistically significant.Results: The overall prevalence of urinary tract infection was 16.7% (95% CI 12.4-21.1). Both Gram-negative and Gram-positive bacterial isolates were recovered with a rate of 44/50 (88%) and 6/50 (12%) respectively. Among Gram-negative isolates, E. coli 28/44(63.6%) was predominant while S. saprophyticus 2/6(33.3%) was prevalent among Gram-positive bacterial isolates. Overall, a high level of resistance to ampicillin, augmentin, and tetracycline was shown by Gram-negative bacteria with a rate of 44/44(100%), 39/44(88.6%), and36/44 (81.8%) respectively. About 33/50(66%) of overall multidrug resistance was observed (95% CI 52-78). About six Gram-negative bacterial isolates were extended spectrum beta-lactamase (ESBL) producers. Having a history of urinary tract infection (P-0.003, AOR 1.86-22.15) and male uncircumcision (p-0.00, AOR 5.5-65.35) were the independent variables that associate for urinary tract infections.Conclusion: In the present study, the prevalence of urinary tract infection among children was high and considerably a high proportion of multidrug resistance was observed. This result will have a significant impact on the selection of appropriate antimicrobial agents for the treatment of urinary tract infection.

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