scholarly journals Lipid Profile in Thyroid Autoimmunity - A Study among Reproductive Age Group Females of Central Kerala

2021 ◽  
Vol 10 (37) ◽  
pp. 3231-3236
Author(s):  
Sindhu Panakkaparambil Surendranath ◽  
Anil Palakkaparambil ◽  
Suchithra Erath Thadathil ◽  
Shibu Thadathil Sreedharan
Keyword(s):  
Lipid Profile ◽  
Thyroid Autoimmunity ◽  
Thyroid Stimulating Hormone ◽  
Reproductive Age ◽  
Age Group ◽  
Positive Group ◽  
Detailed Medical History ◽  
Reproductive Age Group ◽  
Biochemical Abnormalities ◽  
Stimulating Hormone

BACKGROUND One of the most common causes of thyroid dysfunction among women is autoimmunity, especially in fertile age group. Thyroid hormone disorders are associated with a number of biochemical abnormalities including dyslipidaemia, metabolic dysfunctions, spontaneous miscarriage, and preterm delivery. Dyslipidaemia is one of the most common metabolic abnormalities present in patients with thyroid disease. The purpose of this study was to find the association between anti-thyroid peroxidase antibody (anti-TPO) and dyslipidaemia in reproductive age group females from Central Kerala. METHODS A total of 200 asymptomatic women, all in reproductive age group, from a tertiary hospital in Kerala participated in this study. Demographic data and detailed medical history of the participants were collected. Anti-TPO and thyroid stimulating hormone (TSH) were measured using chemiluminescence immunoassay system. Serum lipid profile was estimated using fully automated random-access clinical chemistry analyser EM - 360. Continuous variables were compared between the groups using Mann–Whitney U-test. P value lesser than 0.05 was considered as statistically significant. RESULTS The mean age of the subjects was 32.92 ± 11.82 years. A total of 47 participants (23.5 %) were anti-TPO positive. Abnormality in lipid profile was present in 72.34 % (N = 34) of the anti-TPO positive participants. In the anti-TPO positive group, 51.06 % of the participants had hypercholesterolemia. In the anti-TPO positive group, anti-TPO levels show a statistically significant correlation with total cholesterol and triglyceride levels (P = 0.07 and P < 0.01). A total of 9 % (N = 18) had thyroid stimulating hormone (TSH) values greater than normal range (0.34- 4.25 µIU/mL) suggesting presence of hypothyroidism. TSH values were also significantly associated with lipid profile in the anti-TPO positive group. Both thyroid autoimmunity and dyslipidaemia can affect fertility, pregnancy and other reproductive outcomes. CONCLUSIONS Women should be screened for autoimmune antibodies and associated biochemical abnormalities to estimate and reduce the risk of cardiovascular morbidity, negative pregnancy outcomes and infertility. KEY WORDS Thyroid Autoimmunity, Anti-TPO Antibody, Dyslipidaemia

STUDY OF PATIENTS WITH PCOS (POLYCYSTIC OVARY SYNDROME) AND LIPID PROFILE

2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Anurag Kesarwani ◽  
Darshna Jain
Keyword(s):  
Lipid Profile ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Age Group ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
Healthy Life ◽  
Healthy Life Style ◽  
Reproductive Age Group ◽  
Rotterdam Criteria

Background: Aims of this study was found the association of PCOS with Lipid profile of patients. Methods: Cross sectional Hospital based study conducted on Women at reproductive age (15-45 years) and who presented with Rotterdam Criteria. Results: Mean triglyceride of patients was 113.68±19.25 mg/dl, mean LDL of patients was 95.24±14.94 mg/dl, mean cholesterol of patients was 159.98±18.26 mg/dl and mean HDL of patients was 52.16±6.32 mg/dl Conclusion: PCOS, being a common condition prevailing in women with reproductive age group, is the cause of problem for one in four patients attending a gynecologist. Despite treating the infertility and menstrual complaints of the PCOS patients, it is a treating doctor’s duty to take it as an opportunity to screen for metabolic syndrome and advice for healthy diet, physical activity and weight reduction. Healthy life style modification not only improves their menstrual and ovulatory symptoms, but also prevents the future cardiovascular and other morbid ailments. Keywords: PCOS, LDL, FBS, HDL

scholarly journals Prevalence of Goiter and Associated Factors among Women of Reproductive Age Group in Demba Gofa Woreda, Gamo Gofa Zone, Southwest Ethiopia: A Community-Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Befikaduwa Zekarias ◽  
Frehiwot Mesfin ◽  
Bezatu Mengiste ◽  
Adane Tesfaye ◽  
Lemma Getacher
Keyword(s):  
Logistic Regression ◽  
Iodine Deficiency ◽  
Associated Factors ◽  
Sampling Technique ◽  
Iodized Salt ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Reproductive Age Group

Background. Iodine deficiency disorder is a major public health problem in Ethiopia that is more common in women of reproductive age. However, it is not well addressed and there is a lack of information on its prevalence and associated factors in women of reproductive age group. Therefore, the objective of this study was to assess goiter prevalence and associated factors among women of reproductive age in the Demba Gofa woreda, Gamo Gofa Zone, Southwest Ethiopia. Methods. A community-based cross-sectional study was used among 584 randomly selected women in the reproductive age group from February 05 to April 20, 2016. A simple random sampling technique was used to select the study kebeles, and a systematic random sampling technique was used to select the study samples. Data were collected through a pretested questionnaire, and the goiter examination was done clinically for each participant. The collected data were coded and entered into a computer for statistical analysis using EpiData version 3.2 and analyzed using SPSS version 20. Variables with a P value ≤0.25 in bivariate logistic regression analysis were entered into multivariate logistic regression analysis, and finally, variables with a P value <0.05 in multivariate logistic regression were considered significantly associated with the dependent variable. Results. The total goiter rate was 43%, 95% CI = 39.2–46.9. Cassava consumption (AOR: 2.02, 95% CI: 1.03–4), salt wash before use (AOR: 3.14, 95% CI: 1.1–11.3), salt use after >2 months of purchase (AOR: 11, 95% CI: 5–26), family history of goiter (AOR: 4.6, 95% CI: 1.4–15.8), and poor knowledge of iodized salt (AOR: 2.7, 95% CI: 1.4–5.5) were significant factors associated with goiter. Conclusion. Iodine deficiency was found to be severe in women of reproductive age in the study area. This showed that women of reproductive age, especially during pregnancy, are exposed to iodine deficiency and its adverse effects at delivery. Thus, they need urgent supplementation with iodine, improved access to foods rich in iodine, and intake of iodized salt. Additionally, health education should focus on the importance of iodized salt, the proper method of use, and the prevention of iodine deficiency, which are highly recommended to minimize the problem.

Preference on prenatal sex determination and its associated factors among currently married women of reproductive age group in Puducherry, India

2021 ◽  
Vol 28 (1) ◽  
pp. 51
Author(s):  
GaneshKumar Saya ◽  
KariyarathCheriyath Premarajan ◽  
Gautam Roy ◽  
Sonali Sarkar ◽  
SitanshuSekhar Kar ◽  
...  
Keyword(s):  
Sex Determination ◽  
Associated Factors ◽  
Married Women ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Reproductive Age Group
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