Comparative Study of Lipid Profile in Women Using Oral Contraceptive Pills Versus Non Oral Contraceptive Pills Users in Reproductive Age Group

2017 ◽  
Vol 6 (4 (Part-2)) ◽  
pp. 1037-1040
Author(s):  
Jagjeewan Ram ◽  
◽  
Kamlesh Kumar ◽  
Manoj Kumar Gupta ◽  
◽  
...  
Author(s):  
Tarnima Saha ◽  
Meenakshi K. Bharadwaj ◽  
Shakti Vardhan

Background: Heavy menstrual bleeding (HMB) is one of the commonest presenting complaints in reproductive age group. Although combined oral contraceptives (COCs) are commonly used in such patients, combined hormones by intravaginal route has been found acceptable and effective. Aim of the study is to compare the efficacy and side effects of combined intravaginal hormonal ring (IHR) with COCs in control of HMB in these patients.Methods: Hundred women with HMB fulfilling inclusion criteria were randomized into two equal groups and treated with either IHR or COCs for three cycles. Each cycle consisted of three weeks of IHR/COC use followed by 1-week ring-free/non-hormonal pills period. Outcome measures were change in PBAC score (pictorial blood loss assessment chart), hemoglobin rise, side effects and overall patient satisfaction.Results: The percentage reduction in PBAC score, the duration of menses and increase in hemoglobin levels were statistically significant at the end of study in each group. The PBAC score reduction was 87.37% vs 61.52%, menses duration was 4.24±0.74 versus 5.16±1.67, and hemoglobin increase was 3.16 (95% CI:0.142-1.412) and 1.24 (95% CI:1.048-1.640) in the IHR versus COC group. However, the intergroup reduction of mean PBAC score was not statistically significant. Significantly more ring users were satisfied and elected to continue with treatment.Conclusions: Both the IHR and COCs are effective treatments for HMB in reproductive age group. IHR may be an attractive option for HMB due to better compliance and lesser systemic side-effects.


Author(s):  
Maitri Shah ◽  
Chirayu Parmar ◽  
Riddhi Gor

Background: Dysfunctional uterine bleeding (DUB) is the most common menstrual disorder of women in any age group and is a diagnosis of exclusion. Medical management of menorrhagia is a difficult task as there are wide variations in the available drugs and a lot of different regimes are available. Present study evaluates efficacy and safety of ormeloxifene a selective estrogen receptor modulator (SERMs) as compared to combined oral contraceptive pills in treatment of dysfunctional uterine bleeding in perimenopausal women.Methods: Total 60 patients meeting with our inclusion and exclusion criteria were enrolled in the study over a time period of 6 months and were further divided randomly into two groups. One group was given Ormeloxifene and the other group was treated with combined oral contraceptive pills (COCP) over a period of six months. The outcome variables noted were pictorial blood loss assessment chart (PBAC) score, Hb level and combined endometrial thickness (CET). Quantitative variables were compared using independent t test/Mann-Whitney test between the two groups and paired t Test/Wilcoxon test was used for comparison between pre and post within the group.Results: Both ormeloxifene and COCP significantly reduce blood loss in these patients evidenced by decrease of PBAC score, rise in hemoglobin levels and decrease in CET levels. However, ormeloxifene was found to be superior to COCP in reducing the menstrual blood loss. Ormeloxifene was also tolerated better compared to COCP with fewer side effects experienced by patients.


Author(s):  
Neeti Verma ◽  
Prashant K. Bajpai

Background: Despite the availability of a wide range of contraceptive and mass media campaigns and information, education, and communication programs, population control remains a distant dream to achieve. The low use of spacing methods is reflected by early childbearing and short birth intervals. The present study was undertaken to assess the knowledge, attitude, and practice of different contraceptive methods among married women in the reproductive age group.Methods: A cross-sectional study was conducted among 230 married women in the reproductive age group (18-49 years) attending the outpatient department (OPD) of urban health training centre and came mainly from the neighboring slum locality.Results: We have included a total of 230 participants in the study analysis. Almost all (98.6%) of the study participants had knowledge about at least one method of contraception. If we see the use of contraceptive methods, 163 (70.8%) women ever used any of the contraceptive methods. Less than half (40.9%) had knowledge that contraceptive methods reduce the economic burden on the family. A negative attitude towards the practice of contraception was found among 11.7 percent of women in the study. When asking about present (last 1 year) practice of contraception, 29.1% not practiced any method of contraception, 25.6% used oral contraceptive pills (OCPs), and 27.8% used condoms.Conclusions: The study reveals good knowledge and favorable attitude of rural couples towards contraception. Contraceptive knowledge and practice were influenced by exposure to family planning messages. Women's education and counselling of couples can play an important role in adopting family planning methods.


2021 ◽  
Vol 42 (6) ◽  
pp. 471-476
Author(s):  
Ghada M. Khafagy ◽  
Hebatallah L. Shalaby ◽  
Nagwa E. Saad ◽  
Marwa D. Hasan

Background: Contraceptive agents are widely used by women of reproductive age, and resulting depression is the most common side effect of this usage. This study aimed to study the effect of monthly injectable combined contraceptives versus that of combined oral contraceptive pills (COC) on patients’ mood.Methods: A prospective cohort study was conducted on 124 females aged 18–45 years attending the Kom-Ashfeen Family Medicine Unit, El-Kalyubia, Egypt. Participants were divided into three groups according to their choice: group A included 44 participants who received monthly combined injectable contraceptives (CIC); group B included 40 participants who took COC; and group C included 40 participants who used the copper intrauterine device (IUD). The Patient Health Questionnaire-9 (PHQ-9) score was assessed at the beginning of the study and after 6 months of follow-up.Results: After 6 months of follow-up, there were mild but statistically significant increases in the PHQ-9 score in groups A and B, with group A (CIC users) showing the highest increase. Approximately 34.1%, 27.5%, and 15% of CIC, COC, and IUD users, respectively, moved from the non-depression stage to mild depression after 6 months; this change was statistically significant in groups A and B only.Conclusion: Monthly injectable combined contraceptives and oral contraceptive pills were associated with an increased risk of developing mild depression; this risk was higher in users of CICs, although the difference was not statistically significant. Thus, it is crucial to counsel patients about this possible risk and to follow them up. However, further studies are required to confirm our results.


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