scholarly journals SUMMARY OF CLINICAL GUIDELINES OF THE RUSSIAN ASSOCIATION OF ENDOCRINOLOGISTS VITAMIN D DEFICIENCY IN ADULTS: DIAGNOSIS, TREATMENT AND PREVENTION

2015 ◽  
Vol 18 (2) ◽  
pp. 29-32
Author(s):  
E A Pigarova
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Human Body ◽  
Clinical Guidelines ◽  
Diagnosis And Treatment ◽  
Treatment And Prevention ◽  
The World ◽  
Fat Soluble Vitamins ◽  
Russian Association ◽  
Uv Rays

Vitamin D belongs to the group of fat-soluble vitamins. It is naturally present in only a very limited amount of food, and the synthesis in the human body is possible only under certain conditions - when the UV rays of sunlight fall on the skin. National and foreign studies show that the insufficiency of vitamin D, defined as levels of 25(OH)D less than 30 ng/ml or less than 20 ng/ml, is widespread throughout the world. This publication is a shortened version of the guideline «Vitamin D deficiency in adults: diagnosis, treatment and prevention» which was approved on February 27th, 2015 at the session «National clinical guidelines for the diagnosis and treatment of endocrinopathies» at the VIIth All-Russian Congress of Diabetes.

scholarly journals Állásfoglalás

2012 ◽  
Vol 153 (Supplement 2) ◽  
pp. 5-26 ◽  
Author(s):  
István Takács ◽  
Ilona Benkő ◽  
Erzsébet Toldy ◽  
Norbert Wikonkál ◽  
László Szekeres ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Human Body ◽  
Clinical Guidelines ◽  
General Public ◽  
Decision Makers ◽  
Health Issues ◽  
Medical Associations ◽  
Prevention And Therapy ◽  
Civilized World

The metabolism of vitamin D is unique in the human body and its diverse effects are present in almost every organ. Vitamin D deficiency is one of the most prominent health issues in the civilized world. For the solution of this concern an extensive collaboration is imperative. Recognizing this necessity the most prominent Hungarian medical associations fighting with the effects of vitamin D deficiency worked out a collective consensus on the importance, diagnosis, prevention and suggested therapy of vitamin D deficiency. Along with the clinical guidelines of the different associations, the result of this consensus could serve as guidance for the practicing doctors in the prevention and therapy of vitamin D deficiency. In addition the consensus aims to direct the attention of decision-makers and the general public on the significance of this issue.

scholarly journals The State of Knowledge about Nutrition Sources of Vitamin D, Its Role in the Human Body, and Necessity of Supplementation among Parents in Central Poland

2018 ◽  
Vol 15 (7) ◽  
pp. 1489 ◽  
Author(s):  
Katarzyna Zadka ◽  
Ewelina Pałkowska-Goździk ◽  
Danuta Rosołowska-Huszcz
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Human Body ◽  
Primary Schools ◽  
Education Level ◽  
The Body ◽  
Monthly Income ◽  
Level Of Education ◽  
Central Poland ◽  
Level Of Knowledge

The percentage of children with vitamin D deficiency in Poland is alarming. The aim of the study was to assess the knowledge about sources of food and the function of vitamin D, as well as the frequency of its supplementation. A survey was conducted among the parents of children from Central Poland attending primary schools, and a questionnaire containing mainly open-ended questions was used to collect the data. Most mothers knew at least one of the functions of vitamin D in the body but had a low level of knowledge about its dietary sources. Only a small group of respondents supplemented themselves and their children with vitamin D. Statistically significant influences on the level of knowledge about the functions and sources of vitamin D were place of residence (i.e., better knowledge in the countryside) and mothers’ level of education (i.e., the better educated, the greater knowledge). In the case of monthly income level, such impact was observed only in relation to the knowledge of vitamin D functions. Concerning the frequency of supplementation, only maternal level of education had a statistically significant effect (i.e., the higher the education level, the higher the frequency of supplementation). In addition, mothers who were aware of functions of vitamin D and nutritional sources, significantly more frequently supplemented vitamin D.

Abstract 121: Vitamin D Deficiency Study in Postural Orthostatic Tachycardia Syndrome

2015 ◽  
Vol 8 (suppl_2) ◽  
Author(s):  
Chandralekha Ashangari ◽  
Amer Suleman
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Electronic Medical Records ◽  
Vitamin D3 ◽  
Medical Records ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Vitamin D Levels ◽  
The World ◽  
25 Oh Vitamin D ◽  
Vitamin D3 Deficiency

Objectives The aim of this study is to assess vitamin D levels, including the prevalence of vitamin D deficiency/insufficiency in Postural Orthostatic Tachycardia Syndrome (POTS) patients. Background : The Postural Orthostatic Tachycardia Syndrome (POTS) affects primarily young women. POTS is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. We frequently find vitamin D deficiency in patients who present with POTS Methods: 180 patients were selected randomly from our clinic with POTS. Patients Vitamin D levels charts were reviewed from electronic medical records, 25-OH vitamin D (Vitamin D3 ) status was defined as Normal (>30 ng/mL), Insufficient (20.0-29.9 ng/mL), and deficient (<20 ng/mL). Results: Out of 180 patients, 170 patients are female (94%, n=170, age 31.88±10.36), 10 patients are male (6% ,age 25.83±6.19). 79 patients had vitamin D3 level >30 ng/ml, 10 patients had vitamin D3 level range >20.0 to 29.9 ng/mL, 91 patients had vitamin D3 level < 20ng/mL. Conclusion: Our research results demonstrated that Postural Orthostatic Tachycardia Syndrome (POTS) patients have a higher rate of vitamin D3 deficiency (51% have Vitamin D3 less than 20 ng/mL). Vitamin D3 levels are low in more than half of POTS patients (56% had less than 30 ng/mL )

The roles of vitamin D in increasing the body's immunity and reducing injuries due to viral infections: With an emphasis on its possible role in SARS-CoV-2 (COVID-19)

2021 ◽  
Vol 27 ◽  
Author(s):  
Elahe Aleebrahim-Dehkordi ◽  
Niloofar Deravi ◽  
Shirin Yaghoobpoor ◽  
Dariush Hooshyar ◽  
Mahmoud Rafieian-Kopaei
Keyword(s):  
Vitamin D ◽  
Immune System ◽  
Vitamin D Deficiency ◽  
Viral Infections ◽  
Vitamin D Supplementation ◽  
Angiotensin Converting Enzyme 2 ◽  
Treatment And Prevention ◽  
Lung Injuries ◽  
Novel Coronavirus ◽  
Cytochrome P450 Family

Background: It is known that Vitamin D can increase the body’s immunity against some viral infections. Many people around the world have vitamin D deficiency and, therefore, this has become a public concern whether vitamin D is an important factor protecting against COVID-19 infection. In this paper, the data about the roles of vitamin D on immunity and recovery from viral infections, especially novel Coronavirus disease (COVID-19) is reviewed. Methods: The electronic databases of Pubmed, Google Scholar, Research Gate, Excerpta Media Database (EMBASE) and Medical and Health Education (Medrix) were searched. Results: Vitamin D is considered an important factor in immune homeostasis. Various effects have been considered for this nutrient on the immune system, particularly because of vitamin D receptor (VDR) and Cytochrome P450 Family 27 Subfamily B Member 1 (CYP27B1) expression in most of the immune cells. Vitamin D can raise cellular immunity, reduce cytokine storm and enhance antioxidants production. It also has modulatory effects on Angiotensin-converting enzyme 2 (ACE2) receptors and might have protective functions against acute lung injuries, including COVID-19 infection. However, there are some articles against this positive effect. Conclusion: Vitamin D supplementation is reported to be effective in the enhancement of the immune system and might be effective in the treatment and prevention of COVID-19 infection, especially in those with its deficiency. However, it should be considered that vitamin D deficiency shows the overall health status of the patients and cannot be considered specific for COVID-19 infection.

scholarly journals THE RUSSIAN ASSOCIATION OF COLOPROCTOLOGY CLINICAL GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF HEMORRHOIDS

2019 ◽  
Vol 18 (1) ◽  
pp. 7-38 ◽  
Author(s):  
Yu. A. Shelygin ◽  
S. A. Frolov ◽  
A. Yu. Titov ◽  
L. A. Blagodarny ◽  
S. V. Vasilyev ◽  
...  
Keyword(s):  
Clinical Guidelines ◽  
Diagnosis And Treatment ◽  
Russian Association

scholarly journals Аnaphylactic shock. Сlinical guidelines

2021 ◽  
Vol 18 (1) ◽  
pp. 56-72
Author(s):  
Natalya G. Astafieva ◽  
Ainagul Zh. Bayalieva ◽  
Igor B. Zabolotskikh ◽  
Natalya I. Ilyina ◽  
Alexander V. Kulikov ◽  
...  
Keyword(s):  
Clinical Guidelines ◽  
Anaphylactic Shock ◽  
Treatment And Prevention ◽  
Classification Of Diseases ◽  
Threatening Condition ◽  
International Statistical Classification ◽  
Life Threatening ◽  
The Russian Federation ◽  
Russian Association

Anaphylactic shock is a severe life-threatening condition caused by medicines, food, hymenoptera, animal poisons, etc. Therefore, anaphylactic shock (anaphylaxis) can develop both in medical institution and outside it, and physicians of any specialties should be ready to treat this condition. In this regard, clinical guidelines for anaphylactic shock have been developed. These recommendations were approved by the Russian Association of Allergy and Clinical Immunology (Protocol No. 743/12 dated December 30, 2020) and the Federation of Anesthesiologists and Resuscitators (Protocol No. 1 dated January 13, 2021), approved at a meeting of the Scientific and Practical Council of the Ministry of Health of the Russian Federation (Protocol No. 743/12 dated December 10, 2020). Guidelines covered a number of nosologies corresponding to codes of the International Statistical Classification of Diseases and Related Health Problems: T 78.0; T 78.2; T 80.5; T 88.6. The clinical guidelines systematize modern data on etiology, epidemiology, classification, clinical picture, diagnosis, treatment, and prevention of anaphylactic shock. In addition, an algorithm for managing a patient with anaphylactic shock has been developed. Clinical guidelines for anaphylactic shock are intended for practitioners of all specialties, students, and teachers of medical universities, residents, and graduate students.

scholarly journals 25-Hydroxylase vitamin D deficiency in 27 Saudi Arabian subjects: a clinical and molecular report on CYP2R1 mutations

2021 ◽  
Author(s):  
Sarah Bakhamis ◽  
Faiqa Imtiaz ◽  
Khushnooda Ramzan ◽  
Edward De Vol ◽  
Osamah AlSagheir ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Molecular Genetic ◽  
Clinical Manifestations ◽  
Research Centre ◽  
Heterozygous Mutation ◽  
Hydroxylase Deficiency ◽  
Treatment And Prevention ◽  
Genetic Features ◽  
High Doses

Vitamin-D deficiency remains a major cause of rickets worldwide. Nutritional factors are the major cause and less commonly inheritance causes. Recently, CYP2R1 has been reported as a major factor for 25-hydroxylation contributing to the inherited forms of vitamin D deficiency. We conducted a prospective cohort study at King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia to review cases with 25-hydroxylase deficiency and to describe their clinical, biochemical, and molecular genetic features. We analyzed 27 patients from 9 different families who presented with low 25-OH vitamin-D and not responding to usual treatment. Genetic testing identified two mutations: c.367+1G>A (12/27 patients) and c.768dupT (15/27 patients), where 18 patients were homozygous for their identified mutation and 9 patients were heterozygous. Both groups had similar clinical manifestations ranging in severity, but none of the patients with heterozygous mutation had hypocalcemic manifestations. 13/18 of homozygous patients and all the heterozygous patients responded to high doses of vitamin-D treatment, but they regressed after decreasing the dose, requiring lifelong therapy. 5/18 of homozygous patients required calcitriol to improve their biochemical data, whereas none of the heterozygous patients and patients who carried the c.367+1G>A mutation required calcitriol treatment. To date, this is the largest cohort series analyzeing CYP2R1-related 25-hydroxylase deficiency worldwide, supporting its major role in 25-hydroxylation of vitamin-D. It is suggested that a higher percentage of CYP2R1 mutations might be found in the Saudi population. We believe that our study will help in the diagnosis, treatment, and prevention of similar cases in the future.

Sign in / Sign up

Export Citation Format

Share Document