Federal clinical recommendations on diagnostics and treatment of type 2 diabetes mellitus in the children and adolescents

2014 ◽  
Vol 60 (5) ◽  
pp. 57-68
Author(s):  
Lyubov I Zil’berman ◽  
Tamara L Kuraeva ◽  
Valentina A Peterkova
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Age Groups ◽  
Treatment Strategies ◽  
Clinical Recommendations ◽  
Long Period ◽  
The Past ◽  
Young Subjects

Type 2 diabetes mellitus (DM2) morbidity has increased over the past years. Its rapid growth affects young subjects among those of other age groups including adolescents and pre-pubertal children. The diseases develops in the association with obesity and metabolic syndrome but remains asymptomatic during a long period. Therefore, its detection requires an active diagnostic search. The present clinical recommendations highlight the major problems pertaining to the diagnostic and treatment strategies for the management of the patients presenting with type 2 diabetes mellitus.

scholarly journals Significance of HbA1c targets based on an individual approach to the treatment of patients with type 2 diabetes mellitus

2014 ◽  
Vol 17 (2) ◽  
pp. 4-9 ◽  
Author(s):  
Inna Vladimirovna Misnikova ◽  
Alexander Vasil'evich Dreval ◽  
Yulia Alexandrovna Kovaleva ◽  
Valeria Alekseevna Gubkina ◽  
Aleksey Leonidovich Odnosum
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Microvascular Complications ◽  
Age Groups ◽  
Individual Approach ◽  
The Past ◽  
Hba1c Target ◽  
Hba1c Levels

Background. Over the past few years, special attention has been paid to achieving glycaemic control for type 2 diabetes mellitus (T2DM) patients, since it is a factor for determining the risk of developing macro- and microvascular complications of diabetes. Certain modern guidelines suggest an individual approach to the choice of HbA1c target. Objective. Objective.  . of this study was to estimate the percentage of T2DM patients who have reached the HbA1c levels. This was determined based on their age and the presence of severe complications. Materials and Methods. A total of 2195 patients with T2DM were studied. The patients were divided into the following age groups:

scholarly journals Estimating the disease burden of Korean type 2 diabetes mellitus patients considering its complications

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246635
Author(s):  
Juyoung Kim ◽  
Seok-Jun Yoon ◽  
Min-Woo Jo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Markov Model ◽  
Burden Of Disease ◽  
Age Groups ◽  
Years Of Life Lost ◽  
Age Group ◽  
Disease Study

Background The burden of diabetes is considerable not only globally but also nationally within Korea. The Global Burden of Disease study derived the disability-adjusted life years (DALYs) of diabetes depending on its complications as individual severity using prevalence-based approach from 2017. Conversely, the Korean National Burden of Disease study based on an incidence-based approach does not incorporate the severity of diseases. This study aimed to simulate incidence-based DALYs of type 2 diabetes mellitus (T2DM), given diabetic complications as disease severity using a Markov model. Methods We developed a model with six Markov states, including incident and existing prevalent cases of diabetes and its complications and death. We assumed that diabetes and its complications would not be cured. The cycle length was one year, and the endpoint of the simulation was 100 years. A 5% discount rate was adopted in the analysis. Transition cases were counted by 5-year age groups above 30 years of age. Age- and sex-specific transition probabilities were calculated based on the incident rate. Results The total DALY estimates of T2DM were 5,417 and 3,934 per 100,000 population in men and women, respectively. The years of life lost in men were relatively higher than those in women in most age groups except the 80–84 age group. The distribution of years lived with disability by gender and age group showed a bell shape, peaking in the 55–59 age group in men and 65–69 age group in women. Conclusions The burden of T2DM considering its complications was larger compared to the outcomes from previous studies, with more precise morbid duration using the Markov model.

scholarly journals A patient who does not like insulin

ABOUTOPEN ◽  
2018 ◽  
Vol 4 (1) ◽  
pp. 122-125
Author(s):  
Paola Ubaldi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
General Population ◽  
Bone Metastases ◽  
Cancer Symptoms ◽  
The Past ◽  
The Right ◽  
Hypoglycemic Therapy

Hypoglycemic therapy over the past 20 years has expanded considerably with the use of new classes of more effective and safer medicines. Alongside the aging of the general population, the survival of diabetic subjects has significantly increased, thus exposing them to a greater risk of developing co-morbidities. This represents a challenge for the diabetologist, who must acquire ever broader concepts for the management of a complex and multi-organ disease. We report the case of a 72-year-old woman with type 2 diabetes mellitus and pulmonary adenocarcinoma of the right upper lobe with brain and bone metastases who, subjected to innovative and integrated treatments agreed between specialists of different disciplines, is still alive and free of cancer symptoms 23 months after diagnosis (Diabetology)

Medical service demands of older patients in different age groups in a new model of free Telemedicine

2020 ◽  
Author(s):  
Yu Gong ◽  
Jianyuan Zhou
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Coronary Heart Disease ◽  
Type 2 Diabetes Mellitus ◽  
Heart Disease ◽  
Older Patients ◽  
Medical Service ◽  
Age Groups ◽  
New Model

Abstract Background Medical service for the older patients is a worldwide challenge for public health system. Telemedicine can provide convenient and effective medical service for older patients. But the existing telemedicine models rely upon a direct communication between a doctor and a patient via the Internet but the doctor would be unable to give the patient a direct physical examination, it may lead to diagnostic errors. A new model of telemedicine jointly performed by general practitioners in community health centers and specialists in a university teaching hospital has been established. It is supervised by the government health department and is free for older patients. However, medical service demands of older patients in different age groups applying the new telemedicine are not well characterized. This study is to analyze medical service demands of older patients in different age groups applying the new telemedicine. Methods 472 older patients (aged ≥ 60) were enrolled and were divided into the young older group (aged 60 to 74), the old older group (aged 75 to 89) and the very old group (aged ≥ 90) according to the age stratification for older people defined by World Health Organization. Proportion of the top 10 diseases of older patients of different age groups was analyzed. Results Coronary heart disease and type 2 diabetes mellitus were identified as the top two diseases in the older patients and the young older patients as well as the old older patients applying the new telemedicine. Conclusions The new telemedicine model can provide effective free medical services to older patients. Different medical service demands were identified in different age groups of older patients. Coronary heart disease and type 2 diabetes mellitus were the main diseases of the older patients and young older patients as well as the old older patients applying the new telemedicine. Results of this study will provide basis for the health administrative departments to formulate health policies for older patients. Familiar with the main diseases in different age groups of older patients may provide better medical services to older patients.

scholarly journals Brevibacterium Bacteremia in the Setting of Pyogenic Liver Abscess: A Case Report with Accompanying Literature Review

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Sarah Hossain ◽  
Afif Hossain ◽  
Aldo Barajas-Ochoa ◽  
Michael A. Jaker
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Abdominal Pain ◽  
Oral Intake ◽  
Hepatic Abscess ◽  
Pyogenic Liver Abscess ◽  
The Past ◽  
Unculturable Bacteria

A 71-year-old Pakistani man with poorly controlled type 2 diabetes mellitus presenting with worsening mental status, abdominal pain, and oral intake for the past seven days was found to have pyogenic hepatic abscess with unculturable bacteria and subsequently found to have rare Brevibacterium bacteremia.

scholarly journals Optimizing treatment goals for long-term health outcomes among patients with type 2 diabetes mellitus

2021 ◽  
Vol 9 (1) ◽  
pp. e002396
Author(s):  
Qian Shi ◽  
Yilu Lin ◽  
Vivian A Fonseca ◽  
Lizheng Shi
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Health Outcomes ◽  
Treatment Strategies ◽  
Optimal Treatment ◽  
Treatment Goals ◽  
Macrovascular Complication

IntroductionConsiderable confusions on treatment target have resulted from recent changes in guidelines. Evidence in medical guidelines came from clinical trials with highly selected patients, whereas treatment goals may differ in some subgroups. This study aimed to assess optimal treatment goals (A1C, blood pressure, low-density lipoprotein cholesterol (LDL-C)) for patients with type 2 diabetes mellitus (T2DM), which lead to optimal health outcomes by different treatment strategies.Research design and methodsA retrospective longitudinal study was conducted for veterans with T2DM by using US Veterans Affairs Administrative Database (2005−2015). Medical records were prepared for repeated evaluation performed at 6-month intervals and multivariate longitudinal regression was used to estimate the risk of microvascular and macrovascular complication events. Second-degree polynomial and splines were applied to identify the optimal goals in their associations with lowest risk of clinical outcomes, controlling for demographic characteristics, medical history, and medications.ResultsA total of 124 651 patients with T2DM were selected, with mean of 6.72 follow-up years. In the general population, to achieve the lowest risk of microvascular and macrovascular complication, the optimal goals were A1C=6.81%, LDL-C=109.10 mg/dL; and A1C=6.76%, LDL-C=111.65 mg/dL, systolic blood pressure (SBP)=130.60 mmHg, respectively. The optimal goals differed between age and racial subgroups. Lower SBP for younger patients and lower LDL-C for black patients were associated with better health outcomes.ConclusionsOptimal treatment goals were identified and multi-faceted treatment strategies targeting hyperglycemia and hyperlipidemia and hypertension may improve health outcome in veterans with T2DM. In addition to guidelines’ recommended goals, health systems may examine their own large diverse patients with T2DM for better quality of care.

scholarly journals Case Report: A Confirmed COVID-19 Patient with Type 2 Diabetes Mellitus

2020 ◽  
Vol 2 (3) ◽  
pp. 144-152
Author(s):  
Annisa Nidya Sitepu ◽  
Santi Syafril
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Rna Virus ◽  
Age Groups ◽  
The Elderly ◽  
Postprandial Glucose ◽  
Single Chain

COVID-19 is caused by a novel coronavirus known as SARS-CoV-2, a single chain RNA virus with a particle size of 120-160 nm. Covid-19 can affect almost all age groups, despite, the elderly and people who have records of chronic disease (co-morbid) have the risk to be affected more often and with worse complications from this disease. Diabetes mellitus (DM) is one of the risk factors for enhancing the severity of COVID-19 infection. A 26 years old man, was referred to the hospital with symptoms of shortness of breath, fever, and cough. The patient has no history of comorbidities, but his father has newly type-2 diabetes mellitus (T2DM). The patient was examined, with ad random blood sugar of 220 mg/dL and a chest radiograph suggesting bronchopneumonia. The patient was then examined for fasting and postprandial glucose, HbA1c, and diagnosed with DM, the patient's throat swab showed a positive COVID-19 result. Patients were then treated with antiviral, antibiotic, regulated insulin, and his blood sugar was monitored. The patient's blood sugar is stable and the patient discharge after 34 days of hospitalization.

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