scholarly journals Vibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as anti–cancer polymeric nanomedicines using synchrotron radiation

2018 ◽  
Vol 6 (2) ◽  
pp. 167 ◽  
Author(s):  
Alireza Heidari
Keyword(s):  
Fourier Transform ◽  
Synchrotron Radiation ◽  
Ftir Spectroscopy ◽  
Chemical Structure ◽  
Fourier Transform Infrared ◽  
Considerable Change ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Anti Cancer ◽  
Before And After

Firstly, unsaturated polyamides nanoparticles were hardened by continuous synchrotron radiation and then, the induced changes in its chemical structure were studied by Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. It was shown that applying synchrotron radiation for hardening not only leads to reduction of hardening time but also creates cross link in polymer by breaking Carbon–Carbon double bond, without any considerable change in its chemical structure. In addition, an unsaturated polyamide nanoparticle as anti–cancer polymeric nanomedicines is hardened by synchrotron radiation. Its chemical structure before and after hardening is studied using Raman and Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. The results show that Raman spectroscopy is considerably better than Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy in detecting the changes happened in chemical structure.  

scholarly journals An indirect analytical approach based on ATR-FTIR spectroscopy for determining the FFA content in vegetable oils

RSC Advances ◽  
2020 ◽  
Vol 10 (40) ◽  
pp. 24073-24078
Author(s):  
Yaoyao Dong ◽  
Shaoxia Shi ◽  
Qi Li ◽  
Lingyan Zhang ◽  
Xiuzhu Yu
Keyword(s):  
Fourier Transform ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Ftir Spectroscopy ◽  
Vegetable Oils ◽  
Analytical Approach ◽  
Fourier Transform Infrared ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Novel Approach

In this study, we developed a novel approach for determining a free fatty acid (FFA) in vegetable oils using attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy.

In situ attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy combined with non-negative matrix factorization for investigating the synthesis reaction mechanism of 3-amino-4-amino-oxime furazan

2018 ◽  
Vol 10 (48) ◽  
pp. 5817-5822 ◽  
Author(s):  
Tianlong Zhang ◽  
Ting He ◽  
Chunhua Yan ◽  
Xinyu Gao ◽  
Junxiu Ma ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Reaction Mechanism ◽  
Ftir Spectroscopy ◽  
Matrix Factorization ◽  
Fourier Transform Infrared ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Synthesis Reaction ◽  
Non Negative Matrix Factorization

In situ ATR-FTIR combined with non-negative matrix factorization for investigating the synthesis reaction mechanism of 3-amino-4-aminoximefurazan.

scholarly journals Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) Spectroscopy Analysis of Saliva for Breast Cancer Diagnosis

2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Izabella C. C. Ferreira ◽  
Emília M. G. Aguiar ◽  
Alinne T. F. Silva ◽  
Letícia L. D. Santos ◽  
Léia Cardoso-Sousa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fourier Transform ◽  
Ftir Spectroscopy ◽  
Cancer Patients ◽  
Sensitivity And Specificity ◽  
Fourier Transform Infrared ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Breast Cancer Patients ◽  
Potential Use

Saliva biomarkers using reagent-free biophotonic technology have not been investigated as a strategy for early detection of breast cancer (BC). The attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy has been proposed as a promising tool for disease diagnosis. However, its utilization in cancer is still incipient, and currently saliva has not been used for BC screening. We have applied ATR-FTIR onto saliva from patients with breast cancer, benign breast disease, and healthy matched controls to investigate its potential use in BC diagnosis. Several salivary vibrational modes have been identified in original and second-derivative spectra. The absorbance levels at wavenumber 1041 cm−1 were significantly higher (p<0.05) in saliva of breast cancer patients compared with those of benign patients, and the ROC curve analysis of this peak showed a reasonable accuracy to discriminate breast cancer from benign and control patients. The 1433–1302.9 cm−1 band area was significantly higher (p<0.05) in saliva of breast cancer patients than in control and benign patients. This salivary ATR-FTIR spectral area was prevalidated as a potential diagnostic biomarker of BC. This spectral biomarker was able to discriminate human BC from controls with sensitivity and specificity of 90% and 80%, respectively. Besides, it was able to differentiate BC from benign disease with sensitivity and specificity of 90% and 70%, respectively. Briefly, for the first time, saliva analysis by ATR-FTIR spectroscopy has demonstrated the potential use of salivary spectral biomarkers (1041 cm−1 and 1433–1302.9 cm−1) as a novel alternative for noninvasive BC diagnosis, which could be used for screening purposes.

scholarly journals Attenuated total reflection Fourier‐transform infrared ( ATR ‐ FTIR ) spectroscopy to diagnose osteoarthritis in equine serum

2019 ◽  
Vol 52 (1) ◽  
pp. 46-51 ◽  
Author(s):  
M. Paraskevaidi ◽  
P. D. Hook ◽  
C. L. M. Morais ◽  
J. R. Anderson ◽  
R. White ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Ftir Spectroscopy ◽  
Fourier Transform Infrared ◽  
Total Reflection ◽  
Attenuated Total Reflection

EVALUATION OF RHEOLOGICAL PROPERTIES OF RUBBER COMPOUNDS BASED ON NR BY DETERMINATION OF NR LIPID CONTENTS OBTAINED FROM ATTENUATED TOTAL REFLECTION FOURIER TRANSFORM INFRARED SPECTRA

2020 ◽  
pp. 000-000
Author(s):  
Zohreh Asghari Barzegar ◽  
Saeed Taghvaei Ganjali ◽  
Mercedeh Malekzadeh ◽  
Fereshteh Motiee
Keyword(s):  
Fourier Transform ◽  
Ftir Spectroscopy ◽  
Rheological Properties ◽  
Fourier Transform Infrared ◽  
Total Reflection ◽  
Attenuated Total Reflection ◽  
Nondestructive Technique ◽  
Lipid Contents ◽  
Rubber Compounds ◽  
Cure Time

ABSTRACT This work was done in three stages. In step 1, the lipid content of different natural rubbers (NRs) was evaluated by two methods, extraction and attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, and the obtained results were successfully correlated. In the second step, the correlations between scorch time (Ts2) and optimum cure time (T′c90) of rubber compounds based on natural rubber (NR) and the lipid contents of different types of NR (obtained by two methods) were investigated. The suitable linear behaviors were observed. In the third step, because ATR-FTIR spectroscopy is a fast, simple, and nondestructive technique for characterizing NR, the correlations that were obtained by this method were considered to predict the rheological properties of two case studies. The amounts of Ts2 and T′c90 were estimated by errors of about 20% and 15%, respectively. This new approach is a nondestructive and rapid method for predicting the cure characteristics of the defined NR-based rubber compounds by analyzing small amounts of the species.

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