scholarly journals Indoor Fungal Growth on Variable Antifungal at Different Wall Finishing on Plasterboard

2018 ◽  
Vol 7 (3.23) ◽  
pp. 53
Author(s):  
N M.Sunar ◽  
M Subramaniam ◽  
N F. Zulkifly ◽  
U K. Parjo ◽  
C M. Er ◽  
...  

Various health complaints often been attributed to pollution and the poor quality of the indoor air. If there is good practice in building design, construction, and maintenance, the structures should remain dry. However, when there is moisture damage, the materials may be in contact with water for prolonged times, which inevitably leads to microbial growth or even total deterioration of the building material. Antimicrobial coating is designed to generate a surface that is easy to clean and can also incorporate active agents, commonly called antifungal, that prevent microbial colonization, the subsequent growth and bio-deterioration of the substrate. This paper presents the sustainable treatment for indoor environment quality in buildings by examining the application of potassium sorbate, zinc salicylate, and calcium benzoate that used as food industry preservatives as indoor antimicrobial agents. Four types of wall finishing used on plasterboard substrate: acrylic paint, glycerol based-paint, thin wallpaper, and thick wallpaper. The result indicated that potassium sorbate is the best bio compound to react as antifungal agent to prohibit the growth of indoor fungi. All the antifungal shows difference level of their effectiveness from each other. Only 40% of fungi were able to grow on thin wallpaper by using potassium sorbate as antifungal agent.  

2015 ◽  
Vol 773-774 ◽  
pp. 1116-1120 ◽  
Author(s):  
U.K. Parjo ◽  
Norshuhaila Mohamed Sunar ◽  
Abdul Mutalib Leman ◽  
N.I.A. Ideris ◽  
Paran Gani ◽  
...  

Good indoor environmental quality (IEQ) is desired for a healthy indoor environment. The microbial growth in indoor environments contribute into poor indoor environmental quality can cause various of health problems. Antimicrobial coatings are designed to generate a surface that is easy to clean and can also incorporate active agents, commonly called biocides, which prevent microbial colonization, the subsequent growth and bio-deterioration of the substrate. The aim for this study is to treat indoor environmental quality in buildings by reviewing the possible application of potassium sorbate used in food industry preservatives to be use as indoor antimicrobial. Plasterboard wall was used as a substrate to see the influence of different common wall finishing used such as paints and wallpapers on fungal growth. Potassium sorbate was tested against fungal isolated from affected room M146, FKAAS building. The total fungal counts in affected room was 806 cfu/m3. The ASTM D5590-00 standard was used to evalute fungal growth and potassium sorbate was effective to inhibit the amount of fungal growth on four common types of wall finishing used on plasterboard wall. As a result, the percentage reduction in growth between control and treatment sample were 10% on thin wallpaper, 15% on acrylic paint, 25% on glycerol-based paint and 60% on thick wallpaper.


Author(s):  
Armando Rocha Trinidade ◽  
Hermano Carmo ◽  
José Bidarra

Through the many documents regularly emitted by those dedicated to this activity, it is comparatively easy to describe factual developments in the field of open and distance education in different places in the world. However, it is much more difficult to produce judgements of value about their quality. Quality is a subjective rather than an absolute concept and may be examined from different analytical perspectives: consumers' satisfaction level, intrinsic value of scientific and technical content of learning materials, soundness of learning strategies, efficiency of organisation and procedures, adequate use of advanced technologies, reliability of student support mechanisms, etc. These parameters should be put into the context of specific objectives, nature of target populations and availability of different kinds of resources. In a specific geographic, social, economic and cultural situation a given set of solutions might be judged as adequate and deserving the qualification of "good practice", while in a different context it could be considered of rather poor quality. The selection of examples in this article is the sole responsibility of the authors: neither should the chosen cases be considered as clearly better than any other one, nor missing cases be interpreted as lack of appreciation or a negative judgement. Finally, the authors are aware of the risks of interpreting trends and trying to extrapolate them into the near future: readers should use their own judgement in accepting (or forcefully rejecting) these projections.


2005 ◽  
Vol 52 (3) ◽  
pp. 33-37
Author(s):  
Ivana Cirkovic ◽  
Vera Mijac ◽  
Milena Svabic-Vlahovic ◽  
S. Dukic ◽  
I. Ilic ◽  
...  

Objectives: The application of Central Venous Catheters (CVC) is associated with increased risk of microbial colonization and infection. The aim of present study was to assess the frequency of pathogens colonizing CVC and to determine their susceptibility pattern to various antimicrobial agents. Materials and methods: A total of 253 samples of CVC from intensive care units (ICU) patients were received for culture during 2003. All microorganisms were identified by standard microbiological methods and the susceptibility to antimicrobial agents was determined according to NCCLS recommendations. Results: A total of 184 (72.7%) cultures were positive and 223 pathogens were isolated. Coagulase negative staphylococci (CNS) were the dominant isolates (24.7%), followed by Enterobacter spp. (12.1%), Pseudomonas spp. (11.7%), Enterococcus spp. (9.9%), Klebsiella spp. (8.6%), Candida spp. (7.6%), Acinetobacter spp. (7.6%), other Gram negative nonfermentative bacilli (5.8%), Serratia spp. (4.5%), Staphylococcus aureus (2.6%), Proteus mirabilis (2.2%), E. coli (1.8%) and Citrobacter spp. (0.9%). Meropenem (84.5%) and vancomycin (100%) remain the most effective antimicrobial agents against Gram negative and Gram positive bacteria, respectively. Conclusion: Gram negative bacilli and CNS are the commonest microorganisms colonizing CVC from ICU patients. The increasing resistance of the bacteria to antimicrobial agents is the major problem in spite of restricted policy of using antimicrobial agents in ICU.


1979 ◽  
Vol 42 (10) ◽  
pp. 780-783 ◽  
Author(s):  
J. D. BALDOCK ◽  
P. R. FRANK ◽  
PAUL P. GRAHAM ◽  
FRANK J. IVEY

Sixty, seventy and ninety-day-old country cured hams were used to evaluate potassium sorbate as a fungistatic agent during aging and holding for market. A 1-min spray of 5% (w/v) potassium sorbate offered the lowest effective level for inhibition of fungal growth. Mold and yeast colony counts 30 days post-treatment were significantly lower than initial numbers but protection was lost by the 60th day under conditions conducive to fungal outgrowth (21 ± 5 C and 70 ± 5% relative humidity). Greater mold inhibition was noted when a 10% potassium sorbate spray was used under identical conditions. Less than 65% relative humidity inhibited mold growth on 120-day-old ham slices held at 7 C. Mold and yeast counts tended to be lower on hams treated after 60 days of processing than on hams treated after 90 days of processing. Residual concentrations of sorbic acid required to inhibit mold growth and yield an acceptable ham after 30 days storage were within the limit approved by the Food and Drug Administration for other food products.


1995 ◽  
Vol 58 (7) ◽  
pp. 817-819 ◽  
Author(s):  
JOGINDER SINGH BERWAL ◽  
DINCHEV DINCHO

Mold strains T11 and T19 belonging to Penicillium camemberti and N1 of Penicillium nalgiovensis were used as protective cultures for production of raw dry sausages. Their use completely eliminated the growth of undesirable molds, originating from the natural house mycoflora, which often produce mycotoxins and lead to several other defects. Potassium sorbate (KS), an antifungal agent, was also tested for protecting sausages against the growth of molds but its effect was short lived. The use of T11, T19 and N1 mold strains also improved the organoleptic qualities of the sausages.


2020 ◽  
Vol 85 (11) ◽  
pp. 3920-3926
Author(s):  
Luana Izzo ◽  
Carlos Luz ◽  
Alberto Ritieni ◽  
Juanma Quiles Beses ◽  
Jordi Mañes ◽  
...  

1984 ◽  
Vol 47 (7) ◽  
pp. 508-511 ◽  
Author(s):  
STEVE L. TAYLOR ◽  
MARCI W. SPECKHARD

Potassium sorbate at a concentration of 0.5% inhibited growth and histamine production by selected strains of Proteus morganii and Klebsiella pneumoniae in a trypticase-soy broth fortified with histidine (TSBH medium). At 32°C, the inhibition was effective for up to 120 h of incubation; at 10°C, the inhibition was observed through 216 h of incubation. Sodium hexametaphosphate and sodium polyphosphate did not inhibit growth of these histamine-producing bacteria at 32°C, but did slow the rate of histamine production at the 2% level. The extent of reduction of bacterial histamine production by sodium hexametaphosphate and sodium polyphosphate was most pronounced for P. morganii. Sodium chloride at levels up to 2.0% was ineffective in preventing bacterial growth and histamine production.


2003 ◽  
Vol 37 (3) ◽  
pp. 420-432 ◽  
Author(s):  
Margaret M Pearson ◽  
P David Rogers ◽  
John D Cleary ◽  
Stanley W Chapman

OBJECTIVE: To review the pharmacology, in vitro susceptibility, pharmacokinetics, clinical efficacy, and adverse effects of voriconazole, a triazole antifungal agent. DATA SOURCES: A MEDLINE search, restricted to English language, was conducted from 1990 to June 2002. Supplementary sources included program abstracts from the Interscience Conference on Antimicrobial Agents and Chemotherapy and the Infectious Diseases Society of America from 1996 to 2001 and manufacturer information available through the Food and Drug Administration's Web site. DATA EXTRACTION: All published and unpublished trials and abstracts citing voriconazole were selected. DATA SYNTHESIS: Voriconazole has shown in vitro activity against many yeasts and a variety of mold and dermatophyte isolates. Voriconazole can be administered either orally or parenterally. It exhibits good oral bioavailability, wide tissue distribution including distribution into the central nervous system, and hepatic metabolism. Drug interactions occur through inhibition of the CYP2C9, CYP2C19, and CYP3A4 isoenzymes, resulting in alterations in kinetic parameters of either voriconazole or the interacting agent. Efficacy has been illustrated in open, noncomparative studies of aspergillosis in immunocompromised patients. Human case reports describe successful treatment of rare fungal pathogens. The most commonly reported adverse events include visual disturbances and elevations in liver function tests. CONCLUSIONS: Voriconazole is at least as effective as amphotericin B in the treatment of acute invasive aspergillosis in immunocompromised patients. It has similar efficacy as fluconazole in treatment of esophageal candidiasis. Voriconazole did not achieve statistical non-inferiority to liposomal amphotericin B for empirical therapy in patients with neutropenia and persistent fever, diminishing enthusiasm for use in this indication until additional trials are completed. Based on case reports and in vitro efficacy, voriconazole may prove to be a clinically useful agent in the treatment of other fungal disease.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Biyan He ◽  
Guangnan Ou ◽  
Changyi Zhou ◽  
Meihong Wang ◽  
Suyan Chen

The shortage of new antimicrobial drugs and increasing resistance of microbe to antimicrobial agents have been of some concern. The formulation studies of new antibacterial and antifungal agents have been an active research field. Ionic liquids are known as designed liquids with controllable physical/chemical/biological properties and specific functions, which have been attracting considerable interest over recent years. However, no attention has been made towards the preparation of ionic liquids with antimicrobial activities. In this paper, a new class of ionic liquids (ILs) with fumarate anion was synthesized by neutralization of aqueous 1-butyl-3-methylimidazolium hydroxide with equimolar monoester fumarate and characterized using NMR and thermal gravimetric analysis. The ILs are soluble in water and polar organic solvents and also soluble in the common ILs. The antimicrobial activities of the ILs are more active than commercially available potassium sorbate and are greatly affected by the alkyl chain length. The significant antimicrobial properties observed in this research suggest that the ILs may have potential applications in the modern biotechnology.


1982 ◽  
Vol 45 (4) ◽  
pp. 374-383 ◽  
Author(s):  
MICHAEL C. ROBACH ◽  
JOHN N. SOFOS

Extensive research conducted in recent years has examined the efficiency of both potassium sorbate and sorbic acid (sorbates) as antimicrobial agents in a wide range of processed meat, and fresh and processed poultry products. In addition to their action against pathogens, effects of sorbates on product shelf-life, sensory qualities, and nitrosamine formation have also been examined in laboratory, pilot plant and commercial scale studies. The use of sorbates in these products appears to extend several benefits to both producers and consumers. Extensive studies involving bacon have shown a major reduction in nitrosamine levels associated with inclusion of potassium sorbate and reduction of sodium nitrite in the curing brine. Simultaneously, the low sodium nitrite/potassium sorbate combinations have maintained or even improved antibotulinal activity in temperature-abused products. In addition, potassium sorbate or sorbic acid have delayed growth and toxin production by Clostridium botulinum in other products including cooked and cured red meat and poultry sausages. The compounds have also been shown to extend the shelf-life and delay growth of other pathogenic microorganisms in several products including bacon; cooked, cured meat sausages; cooked, cured or uncured poultry products; fresh poultry; and other meats, including dry cured and fermented products. Sensory evaluation studies have shown that sorbate levels recommended for use in these products (0.26%) do not have adverse effects on product quality characteristics. Allergic type symptoms attributed to experimental bacon from one study were not linked directly with either potassium sorbate or other formulation ingredients, and all available information does not indicate development of any adverse effects from use of sorbates at recommended levels. In summary, the results of studies conducted in meat products indicate that sorbates deserve consideration as potential alternatives to current formulations or processes involved in the manufacture of processed meat and fresh and processed poultry products.


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