scholarly journals Effect of Salivary pH on Water Absorption and Solubility of Enhanced Resin- Modified Glass Ionomer Enhanced Resin- Modified Glass Ionom

2020 ◽  
Vol 27 (3) ◽  
Author(s):  
Yosi Kusuma Eriwati ◽  
◽  
Muhammad Dhiaulfikri ◽  
Ellyza Herda ◽  
◽  
...  
Keyword(s):  
Water Absorption ◽  
Immersion Time ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Absorption Capacity ◽  
Water Absorption Capacity ◽  
Glass Ionomer ◽  
Immersion Period ◽  
Resin Modified Glass Ionomer ◽  
Ph Level

The influence of immersion period and liquid pH on water absorption capacity and solubility of the resin-modified glass ionomer cement (RMGIC) raises the question of whether the critical pH of hydroxyapatite and fluoroapatite influences the water absorption capacity and solubility of enhanced resin-modified glass ionomer (ERMGI). Objective: This study was designed to investigate the effects of immersion periods and various pH levels of artificial saliva on the water absorption and solubility of RMGIC and ERMGI. Methods: Fifty-four disc-shaped specimens (15 mm x 1 mm) of enhanced RMGI (ACTIVATM BioACTIVE-RESTORATIVE, Pulpdent, Watertown, MA, USA) and 54 disc-shaped specimens (15 mm x 1 mm) of RMGIC (Fuji II LC Capsules, GC Corp, Tokyo, Japan) were prepared. Both materials were divided into 9 groups based on artificial saliva pH (pH 7, pH 5.5, and pH 4.5) and immersion time (1, 7, and 14 days). Water absorption and solubility were measured based on ISO 4049: 2009. Data were analyzed statistically using one-way ANOVA. Results: The results showed significant differences in water absorption and solubility value between RMGIC and enhanced RMGI for all the groups. Both materials showed increased water absorption and solubility when immersed in artificial saliva that exhibited a lower pH level and under higher immersion period. Conclusion: Lower pH levels and longer immersion time influence the water absorption and solubility of enhanced RMGI and RMGIC.

scholarly journals Bond strength of a resin composite and a resin-modified glass-ionomer cement associated or not with chlorhexidine to eroded dentin

2015 ◽  
Vol 18 (2) ◽  
pp. 31
Author(s):  
Flavia Pardo Salata Nahsan ◽  
Martha Beteghelli Michielin ◽  
Luciana Mendonça Da Silva ◽  
Camila Moreira Machado ◽  
Andréa Mello De Andrade ◽  
...  
Keyword(s):  
Bond Strength ◽  
Resin Composite ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Acrylic Resin ◽  
Cervical Region ◽  
Glass Ionomer ◽  
Resin Modified Glass Ionomer ◽  
Prior Application ◽  
Ionomer Cement

<p><strong>Objective</strong>: Even resin composites and glass-ionomer cements are widely used for dental cervical region restorations, under erosive condition they can wear out quickly. This study aimed to compare, by means of bond strength by microshear, the performance of a resin composite (RC) and a resin-modified glass-ionomer cement (RMGIC) to eroded dentin and its association with 2% chlorhexidine up to 6 months. <strong>Material</strong> <strong>and</strong> <strong>Methods</strong>:. Eighty  sound third molars teeth were cutt to obtain flat coronal dentin, which were subsequently embedded in self-curing acrylic resin circular molds exposing only this surface available. Teeth were divided into two groups, according to the treatment with the Adper Single Bond 2 + RC Filtek Z250 (Z) or the RMGIC Vitremer (V). Half of the specimens were immersed in artificial saliva-AS for 24 hours (control groups) and half subjected to 3x/1 minute daily immersion in Regular Coca Cola ®-RC for 5 days. Half of the specimens for each described condition were treated with water and half with 2% chlorhexidine for 1 minute prior the restoration. For all groups, the specimens were stored in artificial saliva weekly renewed up to tests. The bonding strength was evaluated by  microshear test after 1 month and 6 months . Data, in normal distribution, were analyzed with 3-way ANOVA and Tukey (p &lt;0.05). <strong>Results</strong>: Challenge factors, materials and time were statistically significant.. Restorations with Z showed significantly higher bond strength compared to V in all situations. There was a reduction in bond strength values over time for all tested conditions. The prior application of 2% chlorhexidine was able to preserve the Z bond strength between 1 and 6 months, but this factor was not statistically significant. <strong>Conclusion</strong>: For eroded dentin, the use of resin composite seems presents greater bond strength compared to resin-modified glass-material, disregarding their association to chlorhexidine or not.</p>

scholarly journals Effects of Ions-Releasing Restorative Materials on the Dentine Bonding Longevity of Modern Universal Adhesives after Load-Cycle and Prolonged Artificial Saliva Aging

Materials ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 722 ◽  
Author(s):  
Salvatore Sauro ◽  
Irina Makeeva ◽  
Vicente Faus-Matoses ◽  
Federico Foschi ◽  
Massimo Giovarruscio ◽  
...  
Keyword(s):  
Bond Strength ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Load Cycle ◽  
Fractographic Analysis ◽  
Glass Ionomer ◽  
Microtensile Bond Strength ◽  
Resin Modified Glass Ionomer ◽  
Universal Adhesives ◽  
Ionomer Cement

This study aimed at evaluating the microtensile bond strength (MTBS) and fractographic features of dentine-bonded specimens created using universal adhesives applied in etch-and-rinse (ER) or self-etching (SE) mode in combination with modern ion-releasing resin-modified glass-ionomer cement (RMGIC)-based materials after load cycling and artificial saliva aging. Two universal adhesives (FTB: Futurabond M+, VOCO, Germany; SCU: Scotchbond Universal, 3M Oral Care, USA) were used. Composite build-ups were made with conventional nano-filled composite (AURA, SDI, Australia), conventional resin-modified glass ionomer cement (Ionolux VOCO, Germany), or a (RMGIC)-based composite (ACTIVA, Pulpdent, USA). The specimens were divided in three groups and immersed in deionized water for 24 h, load-cycled (350,000 cycles; 3 Hz; 70 N), or load-cycled and cut into matchsticks and finally immersed for 8 months in artificial saliva (AS). The specimens were cut into matchsticks and tested for microtensile bond strength. The results were analyzed statistically using three-way ANOVA and Fisher’s LSD post hoc test (p < 0.05). Fractographic analysis was performed through stereomicroscope and FE-SEM. FTB showed no significant drop in bond strength after aging. Unlike the conventional composite, the two RMGIC-based materials caused no bond strength reduction in SCU after load-cycle aging and after prolonged aging (8 months). The SEM fractographic analysis showed severe degradation, especially with composite applied on dentine bonded with SCU in ER mode; such degradation was less evident with the two GIC-based materials. The dentine-bond longevity may be influenced by the composition rather than the mode of application (ER vs. SE) of the universal adhesives. Moreover, the choice of the restorative material may play an important role on the longevity of the finalrestoration. Indeed, bioactive GIC-based materials may contribute to maintain the bonding performance of simplified universal adhesives over time, especially when these bonding systems are applied in ER mode.

scholarly journals Effects of Polyacrylic Acid Pre-Treatment on Bonded-Dentine Interfaces Created with a Modern Bioactive Resin-Modified Glass Ionomer Cement and Subjected to Cycling Mechanical Stress

Materials ◽  
2018 ◽  
Vol 11 (10) ◽  
pp. 1884 ◽  
Author(s):  
Salvatore Sauro ◽  
Vicente Faus-Matoses ◽  
Irina Makeeva ◽  
Juan Manuel Nuñez Martí ◽  
Raquel Gonzalez Martínez ◽  
...  
Keyword(s):  
Bond Strength ◽  
Mechanical Stress ◽  
Polyacrylic Acid ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Bonding Interface ◽  
Glass Ionomer ◽  
Resin Modified Glass Ionomer ◽  
Load Cycling ◽  
Pre Treatment

Objectives: Resin-modified glass ionomer cements (RMGIC) are considered excellent restorative materials with unique therapeutic and anti-cariogenic activity. However, concerns exist regarding the use of polyacrylic acid as a dentine conditioner as it may influence the bonding performance of RMGIC. The aim of this study was to evaluate the effect of different protocols for cycling mechanical stress on the bond durability and interfacial ultramorphology of a modern RMGIC applied to dentine pre-treated with/without polyacrylic acid conditioner (PAA). Methods: The RMGIC was applied onto human dentine specimens prepared with silicon-carbide (SiC) abrasive paper with or without the use of a PAA conditioner. The specimens were immersed in deionised water for 24 h then divided in 3 groups. The first group was cut into matchsticks (cross-sectional area of 0.9 mm2) and tested immediately for microtensile bond strength (MTBS). The second was first subjected to load cycling (250,000 cycles; 3 Hz; 70 N) and then cut into matchsticks and tested for MTBS. The third group was subjected to load cycling (250,000 cycles; 3 Hz; 70 N), cut into matchsticks, and then immersed for 8 months storage in artificial saliva (AS); these were finally tested for MTBS. The results were analysed statistically using two-way ANOVA and the Student–Newman–Keuls test (α = 0.05). Fractographic analysis was performed using FE-SEM, while further RMCGIC-bonded dentine specimens were aged as previously described and used for interfacial ultramorphology characterisation (dye nanoleakage) using confocal microscopy. Results: The RMGIC applied onto dentine that received no pre-treatment (10% PAA gel) showed no significant reduction in MTBS after load cycling followed by 8 months of storage in AS (p > 0.05). The RMGIC–dentine interface created in PAA-conditioned SiC-abraded dentine specimens showed no sign of degradation, but with porosities within the bonding interface both after load cycling and after 8 months of storage in AS. Conversely, the RMGIC–dentine interface of the specimens with no PAA pre-treatment showed no sign of porosity within the interface after any of the aging protocols, although some bonded-dentine interfaces presented cohesive cracks within the cement after prolonged AS storage. However, the specimens of this group showed no significant reduction in bond strength (p < 0.05) after 8 months of storage in AS or load cycling (p > 0.05). After prolonged AS storage, the bond strength value attained in RMGIC–dentine specimens created in PAA pre-treated dentine were significantly higher than those observed in the specimens created with no PAA pre-treatment in dentine. Conclusions: PAA conditioning of dentine prior to application of RMGIC induces no substantial effect on the bond strength after short-term storage, but its use may increase the risk of collagen degradation at the bonding interface after prolonged aging. Modern RMGIC applied without PAA dentine pre-treatment may have greater therapeutic synergy with saliva during cycle occlusal load, thereby enhancing the remineralisation and protection of the bonding interface.

scholarly journals Penyerapan Air Dan Kelarutan Bahan Semen Ionomer Kaca Sebagai Penutup Pit Dan Fisur Gigi

2018 ◽  
Vol 16 (1) ◽  
pp. 106-118
Author(s):  
Emma Krisyudhanti
Keyword(s):  
Water Absorption ◽  
Immersion Time ◽  
Water Solubility ◽  
Glass Ionomer Cement ◽  
Glass Ionomer ◽  
Constant Mass ◽  
Occlusal Surfaces ◽  
Significant Difference ◽  
Value Of Water ◽  
Ionomer Cement

BACKGROUND: Pit and fissure sealants are materials that are often used for preventive maintenance, especially on occlusal surfaces of teeth that are susceptible to caries. All restoration materials that come into contact with water will experience 2 mechanisms, namely the absorption of water, which causes matrix swelling and increased mass and water solubility, namely the release of components from unreacted monomers and causing reduced mass. OBJECTIVE: Measure the value of water absorption and solubility of glass ionomer cement as a cover of the pit and fissure of the tooth. METHODS: 18 specimens of glass ionomer cement sealant material manipulated according to the manufacturer's instructions consisted of six specimens measuring 15 mm in diameter and 1 mm in thickness made for each immersion time. The specimen was put into a desiccator at 37°C for 22 hours and then put into another desiccator with a temperature of 23°C for 2 hours. The specimen was weighed with a precision scale of 0.1 mg. Measurements are carried out repeatedly until a constant mass is obtained (M1). Next, the specimen was put into 40 ml of aquabides and stored in a desiccator at 37°C for 1 day, 2 days and 7 days. At the end of each immersion time, the specimen was removed from aquabides, dried with suction paper and vibrated in the air for 15 seconds. Specimens are weighed to get M2. The specimens were reconditioned to the desiccator at 37°C for 22 hours and then put into another desiccator with a temperature of 23°C for 2 hours and this procedure was repeated one day later, then the mass was weighed repeatedly until a constant mass was obtained (M3). RESEARCH RESULTS: The Kruskal-Wallis statistical test shows that there is no significant difference in the average water absorption value and solubility of materials for immersion for 1 day, 2 days and 7 days. CONCLUSIONS AND RECOMMENDATIONS: The absorption rate of glass ionomer cement as a cover of dental pit & fissure decreased until the second day and increased until the seventh day, with an average absorption of water for 1 day immersion of 42.68mg/mm³, 2 days 40, 53mg/mm³ and 7 days 42.99mg/mm³. Solubility value in water of glass ionomer cement as a cover of dental pit & fissure decreased until the second day then increased until the seventh day, with an average solubility of material for immersion for 1 day at 41.46mg/mm³, 2 days 39.39mg/mm³ and 7 days 41,91mg/mm³. It was said that there was no significant difference in the value of water absorption and solubility of materials during the immersion period of 1, 2 and 7 days. It is recommended that in the application of glass ionomer cement as a cover of dental pits and fissures, please note in the provision of varnish or protector to reduce the occurrence of water absorption and solubility of the material. In addition, the pit and fissure of the tooth that has been covered should be controlled 3 months later to find out if the cover is still intact or has been damaged or loose. It is also recommended that there is further research to determine the value of water absorption and solubility of ingredients if soaked in artificial saliva for more than 7 days.

scholarly journals Effect of Zirconia and Alumina Fillers on the Microstructure and Mechanical Strength of Dental Glass Ionomer Cements

2016 ◽  
Vol 10 (1) ◽  
pp. 58-68 ◽  
Author(s):  
Júlio C. M. Souza ◽  
Joel B. Silva ◽  
Andrea Aladim ◽  
Oscar Carvalho ◽  
Rubens M. Nascimento ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Thermal Cycling ◽  
Resin Composite ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Control Group ◽  
Glass Ionomer Cements ◽  
Glass Ionomer ◽  
Inorganic Particles ◽  
Resin Modified Glass Ionomer

Background: Glass-ionomer cements perform a protective effect on the dentin-pulp complex considering the F ions release and chemical bonding to the dental structures. On the other hand, those materials have poor physic-mechanical properties in comparison with the restorative resin composite. The main aim of this work was to evaluate the influence of zirconia and/or alumina fillers on the microstructure and strength of a resin modified glass-ionomer cement after thermal cycling. Methods: An in vitro experimental study was carried out on 9 groups (n = 10) of cylindrical samples (6 x 4 mm) made from resin modified glass-ionomer (Vitremer, 3M, USA) with different contents of alumina and/or zirconia fillers. A nano-hybrid resin composite was tested as a control group. Samples were mechanically characterized by axial compressive tests and electron scanning microscopy (SEM) coupled to energy dispersive X-ray spectrophotometry (EDS), before and after thermal cycling. Thermal cycling procedures were performed at 3000, 6000 and 10000 cycles in Fusayama´s artificial saliva at 5 and 60 oC. Results: An improvement of compressive strength was noticed on glass-ionomer reinforced with alumina fillers in comparison with the commercial glass ionomer. SEM images revealed the morphology and distribution of alumina or zirconia in the microstructure of glass-ionomers. Also, defects such as cracks and pores were detected on the glass-ionomer cements. The materials tested were not affected by thermal cycling in artificial saliva. Conclusion: Addition of inorganic particles at nano-scale such as alumina can increase the mechanical properties of glass-ionomer cements. However, the presence of cracks and pores present in glass-ionomer can negatively affect the mechanical properties of the material because they are areas of stress concentration.

Microtensile Bond Strength of Resin-Modified Glass Ionomer Cement to Sound and Artificial Caries–Affected Root Dentin With Different Conditioning

2017 ◽  
Vol 42 (6) ◽  
pp. 626-635 ◽  
Author(s):  
A Saad ◽  
G Inoue ◽  
T Nikaido ◽  
M Ikeda ◽  
MF Burrow ◽  
...  
Keyword(s):  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Glass Ionomer ◽  
Microtensile Bond Strength ◽  
Treatment Groups ◽  
Carious Lesions ◽  
Resin Modified Glass Ionomer ◽  
High Incidence ◽  
Root Dentin ◽  
Ionomer Cement

SUMMARY In this laboratory study, the microtensile bond strengths (μTBS) of resin-modified glass ionomer cement (RM-GIC) to sound and artificial caries–affected bovine root dentin (ACAD) using three different conditioning agents were evaluated after 24 hours and three months. The fractured interface was examined with a scanning electron microscope (SEM). Specimens were created on bovine root dentin that was embedded in epoxy resin. For the ACAD specimens, artificial carious lesions were created. The RM-GIC (Fuji II LC) was applied either directly (no treatment), after application of self conditioner, cavity conditioner, or 17% ethylenediamine tetraacetic acid (EDTA) applied for 60 seconds, on sound dentin and ACAD, then light cured. They were stored in artificial saliva for 24 hours or three months. Following this, the specimens were cut into sticks for the μTBS test, and the failure mode of the debonded specimens was examined by using SEM. Pretest failures were excluded from the statistical analysis of the μTBS values because of their high incidence in some groups. Results showed that the μTBS values were significantly affected by the dentin substrate as well as the conditioning agent. Self conditioner provided the highest and most stable μTBS values, while cavity conditioner showed stable μTBS values on sound dentin. Both self conditioner and cavity conditioner had significantly higher μTBS values than the no treatment groups. EDTA conditioning reduced the μTBS after three months to sound dentin, while it showed 100% pretest failure with ACAD for both storage periods.

scholarly journals Pengaruh Perendaman Jus Jeruk Terhadap Kekuatan Tekan Glass Ionomer Cement dan Resin Modified Glass Ionomer Cement

2021 ◽  
Vol 9 (1) ◽  
pp. 1-9
Author(s):  
Claudia Florencita Ediharsi ◽  
Dedi Sumantri ◽  
Arymbi Pujiastuty
Keyword(s):  
Compressive Strength ◽  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Control Group ◽  
Glass Ionomer ◽  
Control Group Design ◽  
Resin Modified Glass Ionomer ◽  
Gold Label ◽  
The Mean ◽  
Ionomer Cement

Glass ionomer cement and resin modified glass ionomer cement are one of the restoration materials that are widely used by dentists. Its presence in the oral cavity causes glass ionomer cement and resin modified glass ionomer cement often in contact with food and beverages such as tangerine juice which can affect the compressive strength. The purpose of this study is to determine the effect of immersion in tangerine juice towards the compressive strength of glass ionomer cement and resin modified glass ionomer. This study was a true experimental with a post test only with control group design. Samples were made from GC Fuji 9 GP and GC Gold Label 2 LC with 36 samples each. Samples were divided into two groups. The first group (18 samples of GC Fuji 9 GP and 18 samples of GC Gold Label 2 LC) was immersed in tangerine juice for 24 hours in an incubator at 37°C. The second group (18 samples of GC Fuji 9 GP and 18 samples of GC Gold Label 2 LC) as a control was immersed in artificial saliva for 24 hours in an incubator at 37°C. The compressive strength was determined using a compression machine. The results showed that the mean compressive strength of glass ionomer cement immersed in tangerine juice was 14,03±0,48 MPa and immersed in artifical saliva was 52,08±0,67 MPa. The mean compressive strength of resin modified glass ionomer cement immersed in tangerine juice was 58,98±0,97 MPa and immersed in artifical saliva was 68,28±0,67 MPa. Data were analyzed with Independent T-test showing the results of p<0.05. The conclusion of this study was that there was an effect of immersion in tangerine juice towards the decreasing of the compressive strength of glass ionomer cement and resin modified glass ionomer cement.

scholarly journals Differences in the Amount of Fluoride Release among Fluoride-Releasing Cements

2014 ◽  
Vol 4 (3) ◽  
pp. 78-81
Author(s):  
Takayuki Ueda ◽  
Kaoru Sakurai ◽  
Takashi Koike ◽  
Koichiro Ogami ◽  
Mituhiro Yokomoto ◽  
...  
Keyword(s):  
Artificial Saliva ◽  
Glass Ionomer Cement ◽  
Resin Cement ◽  
Fluoride Ion ◽  
Fluoride Release ◽  
Glass Ionomer ◽  
Ion Release ◽  
Significant Difference ◽  
Resin Modified Glass Ionomer ◽  
Bonferroni Test

ABSTRACT Purpose The abutment teeth of removable partial dentures are susceptible to root surface caries and secondary caries, and such caries sometimes result in crown destruction. In particular, in aged patients, this risk increases due to age-associated gingival recession, periodontal disease, decreased amount of saliva, and inadequate brushing caused by decreased finger motor function. Fluoride-releasing materials may prevent such caries. In this study, we evaluated the amounts of fluoride release from various fluoride-releasing cements based on the amount of fluoride release into artificial saliva. Materials and methods In this study, the following three types of cement were used: Vitremer 2 Paste (3M Health Care: V2 hereafter) and Fuji Luting EX (GC: EX hereafter) as resin-modified glass-ionomer cements, and Clearfil SA Luting (Kuraray Medical: SA hereafter) as a fluoride-containing adhesive resin cement. Using the method indicated by the manufactures, 5 samples (diameter, 8 mm; thickness, 2 mm) for each type of cement were prepared. The samples were immersed in artificial saliva (5 ml) and left at room temperature. The artificial saliva used for immersion was replaced every 24 hours until 14 days after the initiation of immersion and every 48 hours thereafter until after 30 days. Fluoride release was measured in the immersion solution using a combination fluoride ion-selective electrode connected to an ion analyzer. For statistical analysis, one-way analysis of variance and the Bonferroni test were performed to compare the amount of fluoride ion release among the groups (? = 0.05). Results The cumulative amount of fluoride ion release 30 days after the initiation of immersion was the highest for V2 (363.6 ± 87.1 μg/mm2), followed in order by EX (115.6 ± 7.9 μg/mm2) and SA (57.4 ± 23.9 μg/mm2). Significant differences were observed even from 1 day after the initiation of immersion between V2 and EX as well as SA. Concerning daily changes, the amount of fluoride ion release after 1 day was the highest for each type of cement; it was the highest for V2 (89.8 ± 13.5 μg/mm2), followed by SA (35.9 ± 8.3 μg/mm2) and EX (34.3 ± 3.2 μg/mm2). The amount of release gradually decreased after 2 days or more. Significant differences were observed from 1 day after the initiation of immersion between V2 and EX as well as SA. A significant difference between EX and SA was present from 2 until 4 days after the initiation of immersion. Conclusion V2 as a resin-modified glass-ionomer cement showed the highest amount of fluoride release, indicating continuous sustained fluoride release. How to cite this article Ogami K, Yokomoto M, Koike T, Ueda T, Tomura K, Sakurai K. Differences in the Amount of Fluoride Release among Fluoride-Releasing Cements. Int J Prosthodont Restor Dent 2014;4(3):78-81.

Microleakage of class II restoration with zirconia inlay: An in vitro study

2019 ◽  
pp. 61-67
Author(s):  
Xuan Anh Ngoc Ho ◽  
Anh Chi Phan ◽  
Toai Nguyen
Keyword(s):  
Glass Ionomer Cement ◽  
Class Ii ◽  
Resin Cement ◽  
Glass Ionomer ◽  
Resin Modified Glass Ionomer ◽  
Group 2 ◽  
Self Etch ◽  
Ionomer Cement ◽  
Group 1 ◽  
Composite Restoration

Background: Class II restoration with zirconia inlay is concerned by numerous studies about the luting coupling between zirconia inlay and teeth. The present study was performed to evaluate the microleakage of Class II zirconia inlayusing two different luting agents and compare to direct restoration using bulk fill composite. Aims: To evaluate the microleakage of Class II restorations using three different techniques. Materials and methods: The study was performed in laboratory with three groups. Each of thirty extracted human teeth was prepared a class II cavity with the same dimensions, then these teeth were randomly divided into 3 groups restored by 3 different approaches. Group 1: zirconia inlay cemented with self-etch resin cement (Multilink N); Group 2: zirconia inlay cemented with resin-modified glass ionomer cement (Fuji Plus); Group 3: direct composite restoration using bulk fill composite(Tetric N-Ceram Bulk Fill). All restorations were subjected to thermal cycling (100 cycles 50C – 55 0C), then immersed to 2% methylene blue solution for 24 hours. The microleakage determined by the extent of dye penetration along the gingival wall was assessed using two methods: quantitative and semi-quantitative method. Results: Among three types of restorations, group 1 demonstrated the significantly lower rate of leakage compared to the others, while group 2 and 3 showed no significant difference. Conclusion: Zirconia inlay restoration cemented with self-etch resin cement has least microleakage degree when compare to class II zirconia inlay restoration cemented with resin-modified glass ionomer cement and direct composite restoration using bulk fill composite. Key words: inlay, zirconia ceramic, class II restoration, microleakage.

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