scholarly journals The Relationship Between Generalized Joint Hypermobility and Cervical Disc Degeneration, Neck Pain: A Multidisciplinary Clinical Study

2019 ◽  
Author(s):  
Neşe Keser
Keyword(s):  
Clinical Study ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Joint Hypermobility ◽  
Cervical Disc ◽  
Generalized Joint Hypermobility ◽  
The Relationship

scholarly journals Cervical disc degeneration and neck pain

2018 ◽  
Vol Volume 11 ◽  
pp. 2853-2857 ◽  
Author(s):  
Baogan Peng ◽  
Michael J DePalma
Keyword(s):  
Neck Pain ◽  
Disc Degeneration ◽  
Cervical Disc

scholarly journals Correlation between the Expression of Inflammatory Factors and the Degree of Intervertebral Disc Degeneration

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Tuanmao Guo
Keyword(s):  
Intervertebral Disc ◽  
Mrna Expression ◽  
Disc Degeneration ◽  
Inflammatory Factors ◽  
Cervical Disc ◽  
Expression Levels ◽  
Grade Ii ◽  
Pfirrmann Grade ◽  
The Relationship ◽  
Mrna Expression Levels

Objective: To investigate the relationship between the expression of IL-6, IL-8, IL-15, IFN-a, TNF-a and TRPC6 in the disc tissue of patients with cervical disc degeneration. Methods: The expression levels of inflammatory factors IL-6, IL-8, IL-15, IFN-a, TNF-a and TRPC6 were analyzed by RT-PCR, and the correlation between inflammatory factors and Pfirrmann grade and inflammatory factors was analyzed. Results: The mRNA expression levels of IL-6, IL-8, IL-15, TNF - a and TRPC6 were significantly higher in Pfirrmann grade IV-V than in Pfirrmann grade II-III (P< 0.05), and IFN-a expression level in IV-V intervertebral disc samples was significantly lower than that in II-III discs (P<0.05); The mRNA expression levels of IL-6, IL-8, IL-15, TNF - a and TRPC6 were positively correlated with pfirmann grading (P<0.05), IFN - a was negatively correlated with pfirmann grading (P<0.05), IL-6, IL-8, IL-15, TNF - a and TRPC6 were positively correlated with each other(P<0.05), IFN - a was negatively correlated with IL-6, IL-8, IL-15, TNF-a and TRPC6(P<0.05). Conclusion: IL-6, IL-8, IL-15, IFN-a, TNF- a and TRPC6 are closely related to the degree of cervical disc degeneration.

scholarly journals Association of Generalized Joint Hypermobility With a History of Glenohumeral Joint Instability

2010 ◽  
Vol 45 (3) ◽  
pp. 253-258 ◽  
Author(s):  
Kenneth L. Cameron ◽  
Michele L. Duffey ◽  
Thomas M. DeBerardino ◽  
Paul D. Stoneman ◽  
Christopher J. Jones ◽  
...  
Keyword(s):  
New York ◽  
Joint Instability ◽  
Glenohumeral Joint ◽  
Joint Hypermobility ◽  
Cross Sectional ◽  
Physically Active ◽  
Generalized Joint Hypermobility ◽  
Scale Scores ◽  
History Of ◽  
The Relationship

Abstract Context: Little is known about the relationship among sex, generalized joint hypermobility, and glenohumeral joint instability. Objective: To examine the relationship among sex, generalized joint hypermobility scores, and a history of glenohumeral joint instability within a young, physically active cohort and to describe the incidence of generalized joint hypermobility within this population. Design: Cross-sectional cohort study. Setting: United States Military Academy at West Point, New York. Patients or Other Participants: Of the 1311 members of the entering freshman class of 2010, 1050 (80%) agreed to participate. Main Outcome Measure(s): Generalized joint hypermobility was assessed using the Beighton Scale. A history of glenohumeral joint instability was identified via a baseline questionnaire. Results: Most participants (78%) had no signs of generalized joint hypermobility. Only 11 volunteers (1.5%) had Beighton Scale scores of 4 or greater. Logistic regression analysis revealed a relationship between generalized joint hypermobility and a history of glenohumeral joint instability (P  =  .023). When sex and race were controlled, those with a total Beighton Scale score of ≥2 were nearly 2.5 times as likely (odds ratio  =  2.48, 95% confidence interval  =  1.19, 5.20, P  =  .016) to have reported a history of glenohumeral joint instability. A relationship was observed between sex and nearly all individual Beighton Scale items. Although women had higher total Beighton Scale scores than men, sex (P  =  .658) and race (P  =  .410) were not related to a history of glenohumeral joint instability when other variables in the model were controlled. Conclusions: In these participants, generalized joint hypermobility and a history of glenohumeral joint instability were associated.

Adolescent cervical disc degeneration in MRI does not predict adult headache or neck pain: A 5-year follow-up of adolescents with and without headache

Cephalalgia ◽  
2014 ◽  
Vol 34 (9) ◽  
pp. 679-685 ◽  
Author(s):  
Katri Laimi ◽  
Johanna Pitkänen ◽  
Liisa Metsähonkala ◽  
Tero Vahlberg ◽  
Marja Mikkelsson ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Neck Pain ◽  
Disc Degeneration ◽  
Degenerative Changes ◽  
Cervical Disc ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Study ◽  
The Impact

Aim The impact of early degenerative changes of the cervical spine on pain in adulthood is unknown. The objective was to determine whether degeneration in adolescence predicts headache or neck pain in young adulthood. Methods As part of a follow-up of schoolchildren with and without headache, 17-year-old adolescents with headache at least three times a month ( N = 47) and adolescents with no headache ( N = 22) participated in a magnetic resonance imaging (MRI) study of the cervical spine. The same adolescents were re-examined by phone interview at the age of 22 years ( N = 60/69, 87%). Results Mild disc degeneration at the age of 17 years was common, but was not associated with either frequent or intensive headache or neck pain at the age of 22 years. Conclusion: Mild degenerative changes of the cervical spine in 17-year-old adolescents cannot be regarded as a cause of future headache or neck pain.

Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

2020 ◽  
Author(s):  
vadood javadi ◽  
Shadi Sadat Modarres ◽  
Ghazal Zahed ◽  
Reza Shiari ◽  
Khosro Rahmani
Keyword(s):  
Anxiety Disorders ◽  
Joint Hypermobility ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Generalized Joint Hypermobility ◽  
High Prevalence ◽  
And Control ◽  
The Relationship ◽  
Control Study

Abstract Background Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the relationship between the prevalence of hypermobility and anxiety disorders in children. MethodsIn this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

scholarly journals Predictive factors associated with neck pain in patients with cervical disc degeneration

Medicine ◽  
2017 ◽  
Vol 96 (43) ◽  
pp. e8447 ◽  
Author(s):  
Lingde Kong ◽  
Weifeng Tian ◽  
Peng Cao ◽  
Haonan Wang ◽  
Bing Zhang ◽  
...  
Keyword(s):  
Neck Pain ◽  
Disc Degeneration ◽  
Predictive Factors ◽  
Cervical Disc ◽  
Factors Associated
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