Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

2020 ◽  
Author(s):  
vadood javadi ◽  
Shadi Sadat Modarres ◽  
Ghazal Zahed ◽  
Reza Shiari ◽  
Khosro Rahmani
Keyword(s):  
Anxiety Disorders ◽  
Joint Hypermobility ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Generalized Joint Hypermobility ◽  
High Prevalence ◽  
And Control ◽  
The Relationship ◽  
Control Study

Abstract Background Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the relationship between the prevalence of hypermobility and anxiety disorders in children. MethodsIn this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

scholarly journals Prevalence of Generalized Joint Hypermobility in Children with Anxiety Disorders

2020 ◽  
Author(s):  
vadood javadi ◽  
Shadi alsadat Modarres ◽  
Ghazal Zahed ◽  
Reza Shiari ◽  
Khosro Rahmani
Keyword(s):  
Anxiety Disorders ◽  
Joint Hypermobility ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Hypermobility Syndrome ◽  
Generalized Joint Hypermobility ◽  
High Prevalence ◽  
And Control ◽  
Control Study

Abstract Background: Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the association of hypermobility with anxiety disorders in children. Methods: In this case-control study, 93 children ages 8-15 years with anxiety disorders referring to the Child and Adolescent Psychiatry Clinic of Mofid Children’s Hospital, Tehran, Iran, during 2018, were enrolled. The control group consisted of 100 age and sex-matched children without anxiety disorders. Anxiety was evaluated using the Spence Children Anxiety Scale (SCAS). The diagnosis of generalized joint hypermobility was done based on Beighton and Shiari-Javadi criteria. Results: Based on Beighton’s diagnostic criteria 52.7% of the children in the case group and 16% of the children in the control group had generalized joint hypermobility. Moreover, based on Shiari-Javadi criteria, 49.5% and 13% of the children in the case and control groups had generalized joint hypermobility, respectively. Moreover, the internal correlation between the two criteria was 0.91 showing almost complete compatibility between the two (P<0.001). Age was a risk factor that could predict hypermobility in these children. Other variables such as sex, severity, and type of anxiety disorders, and ADHD, were not predictors of hypermobility syndrome. Conclusion: The prevalence of hypermobility was three times higher in children with anxiety disorders and only age was a predictor for the possibility to suffer from generalized joint hypermobility in these children.

scholarly journals Relationship between small for gestational age and aortic intima-media thickness in newborns

2014 ◽  
Vol 54 (1) ◽  
pp. 57 ◽  
Author(s):  
Ahmad Bayu Alfarizi ◽  
Ria Nova ◽  
Julniar Mawardi Tasli ◽  
Theodorus Theodorus
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Intima Media Thickness ◽  
Control Group ◽  
Case Group ◽  
Media Thickness ◽  
And Control ◽  
Aortic Intima ◽  
The Relationship ◽  
Control Study

Background Small for gestational age (SGA) has been associatedwith adult cardiovascular disease. Small for gestational agenewborns may undergo early aortic wall intima-media thickening(aIMT) in utero.Objective To determine the relationship between SGA as a riskfactor for increased aIMT, as a sign of atherosclerosis onset.Methods We conducted a case-control study in the Neonatal Wardand Rooming-in Nursery at Dr. Mohammad Hoesin Hospital,Palembang, between April to June 2012. Subjects were allocatedto either the case group (aIMT 2: 0.9 mm) or to the controlgroup (aIMT <0.9 mm). Newborns were classified as SGA iftheir birthweight (BW) was < l O'h percentile, and appropriatefor gestational age (AGA) if their BW was between lQth - 90'hpercentile, according to the Lubchenco curve. Abdominal aorticintima-media thickness was measured by echocardiographyexamination.Results The case and control groups consisted of 30 n ewbornseach. The proportion of SGA newborns was higher in the casegroup than the control group. The likelihood of infants in the casegroup being SGA was significantly higher compared to the controlgroup, with odds ratio of 10.8 (95%CI 3,26 to 35, 72) . The meanaIMT was significantly higher in SGA than in AGA infants, 0.9(SD 0.16) mm vs. 0.8 (SD 0.13) mm, respectively, with a meandifference of 0, 13 (9 5% CI 0, 050 to 0,209 mm; P"" 0,02).Conclusion Increased aIMT is more likely found in SGA newborns.

scholarly journals Association of Genetic Polymorphisms in FOXA1 with the Progression of Genetic Susceptibility to Gastric Cancer

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Guo-wen Ding ◽  
Xu-yu Gu ◽  
Zhe Dai ◽  
Hui-wen Pan ◽  
Xiao-yan Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Target Gene ◽  
Case Control Study ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
Drinking Status ◽  
And Control ◽  
The Relationship ◽  
Control Study

Objective. To investigate the relationship between polymorphism of FOXA1 gene rs12894364 and rs7144658 and susceptibility to gastric cancer. Methods. A case-control study was conducted to select 577 cases of primary gastric cancer and 678 cases of normal control. We extracted whole blood genomic DNA and amplified the target gene fragment by PCR. The genotyping and allele was tested through a snapshot method. Results. There was no significant difference in the frequency distribution of genotype between the case group and control group (P>0.05). Stratified analyses showed the SNPs were not correlated with the susceptibility of GC according to different age, gender, cigarette smoking, and alcohol drinking status. Conclusion. There is no significant correlation between the polymorphisms of FOXA1 gene rs12894364 and rs7144658 and the risk of gastric cancer.

scholarly journals The correlation between family smoking habits and mosquito coils use with pneumonia incidences in toddlers

2019 ◽  
Vol 2 (2) ◽  
pp. 69-74
Author(s):  
Wiwin Winarsih ◽  
Wiwik Kusumawati ◽  
Anjarwati Anjarwati
Keyword(s):  
Smoking Habits ◽  
Observational Research ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Chi Square ◽  
Study Approach ◽  
The Family ◽  
The Relationship ◽  
Control Study

The incidences of pneumonia in infants Become the second highest cause mortality before reaching the age of 5 years and a health problem in Indonesia. The family of smoking and smoke from burning mosquito coils are the triggers for air pollution, which can lead to pneumonia in infants. The study aims to analyze the relationship between family smoking habits and the use of mosquito coils with the incidence of pneumonia in under-fives. The method of research applied analytic observational research using a case-control study approach. The number of samples in this study was 87 under-fives in the case group and 87 under-fives in the control group. Sampling was conducted by non-probability sampling. A questionnaire was used as a data collecting instrument. Data analysis used chi-square and multiple logistic regression. The results of this study Showed that there was a relationship between family smoking habits and the use of mosquito coils with the incidence of pneumonia in infants. In addition, there were other variables that had a relationship with the incidence of pneumonia in under-fives namely smoking location (OR = 3,046; 95% CI: 1429-6492, p = 0.003), the number of cigarettes (OR = 7.105 ; 95% CI: 3079-16394, p = 0.000), and length of time with smokers (p = 0.000). On the other hand, the variables of father smoker status and the frequency of using mosquito coils were not related to the incidence of pneumonia in under-fives (p value 0.05). It is concluded that family smoking habits, use of mosquito coils, the location of smoking, and number of cigarettes, and  length of time together with smokers were risk factors associated with the incidence of pneumonia in toddlers

Prolonged rooming-in in infancy is associated with generalized anxiety disorder in the adolescent period

2015 ◽  
Vol 27 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Nazan Kaymaz ◽  
Emel Sarı Gökten ◽  
Mehmet Erdem Uzun ◽  
Şule Yıldırım ◽  
Mustafa Tekin ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Generalized Anxiety Disorder ◽  
Child And Adolescent Psychiatry ◽  
Control Group ◽  
Case Group ◽  
Generalized Anxiety ◽  
Bed Sharing ◽  
Self Confidence ◽  
Long Time

Abstract Objective: This study aims to investigate whether anxiety disorders in adolescents have a link with the separation time of bed/bedroom sharing with parents. It also aims to raise awareness in society about the issue of minimizing anxiety disorders in childhood. Methods: A case-control study was conducted in Şevket Yılmaz Training and Research Hospital between June 2013 and May 2014. The participants included 51 adolescents who were diagnosed as generalized anxiety disorder (GAD) with no-comorbidity and 71 healthy adolescents as the control group, who were chosen randomly. Diagnosis of GAD was based on the criteria from the Diagnostic and Statistical Manual of Mental Disorders (4th ed) by child and adolescent psychiatry doctors. The Turkish version of the State-Trait Anxiety Inventory (STAI) was used for the control group. A special survey about demographics and bed-sharing statements was constructed for the purpose of the study. The groups were analyzed in terms of duration of co-sleeping (bed-sharing) and rooming-in (keeping the mother and the baby in same room) with parents during infancy and the development of anxiety disorders in later period. Results: Mean duration of rooming-in was significantly longer in the case group than in the control group (p=0.009). Similarly, mean duration of co-sleeping in the case group was longer than that of the control group. However, this difference was not statistically significant (p=0.529). Conclusion: Sleeping in the same room with children for a long time may result in anxiety disorders in later period due to possible difficulties in bonding and/or less self-confidence.

scholarly journals The Relationship of Physical Activity and Obesity with the Incidence of Hypertension in Adults Aged 26-45 Years in Medan

2019 ◽  
Vol 7 (20) ◽  
pp. 3464-3468 ◽  
Author(s):  
Elida Normiaty Purba ◽  
Heru Santosa ◽  
Fazidah Aguslina Siregar
Keyword(s):  
Physical Activity ◽  
Healthy Lifestyle ◽  
Control Group ◽  
Case Group ◽  
Eating Pattern ◽  
Proportional Allocation ◽  
Simple Logistic ◽  
Relationship Of ◽  
The Relationship ◽  
Control Study

BACKGROUND: The incidence rate of hypertension is increasing in Indonesia concerning unhealthy behaviours such as unhealthy physical activity and eating pattern which trigger obesity. In Indonesia, the prevalence of hypertension in > 18-year-old people was 34.1% in 2018. AIM: The objective of the research was to find out the relationship between physical activity and obesity with the incidence of hypertension in adults (26-45 years old) in Medan. METHODS: The research was done in Medan, using a case-control study design. The samples were 150 hypertension patients, taken by using proportional allocation: 75 of them were in the case group and the other 75 of them were in the control group. The data were gathered by conducting interviews, measurement, and questionnaires and analysed by using simple logistic regression test. RESULTS: The result of the research showed that there was significant relationship of physical activity (p = 0.000; OR = 3.6; 95% CI, 1.802-7.270) and obesity (p = 0.000; OR = 4; 95% CI, 2.030-7.900) with the incidence of hypertension in 26-45-year-old respondents. CONCLUSION: Make a habit of a healthy lifestyle in their daily life by doing physical activity regularly and good eating pattern to forestall hypertension.

A Case-Control Study on the p73 G4A Gene Polymorphism and Susceptibility to Breast Cancer in an Iranian Population

2020 ◽  
Author(s):  
Zeinab TAVAKKOL AFSHARI ◽  
Zahra GHOLIZADEH ◽  
Amin Reza NIKPOOR ◽  
Jalil TAVAKKOL AFSHARI ◽  
Rashin GANJALI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Iranian Population ◽  
Control Group ◽  
Case Group ◽  
Medical Sciences ◽  
Control Groups ◽  
And Control ◽  
Control Study

Background: The tumor protein p73 (TP73) is a homolog of TP53 family. Ectopic p73 overexpression largely mimics p53 activities as a tumor suppressor and activates the transcription of p53-responsive genes and as a result induce apoptosis. This study aimed to investigate the association between p73 G4A polymorphism and the risk of breast cancer in a northeastern Iranian population. Methods: This case-control study was performed on 105 patients who admitted in educational hospitals of Mashhad University of Medical Sciences, Iran during 2013-2015, with breast cancer as case group and 120 healthy women as the control group. PCR-CTPP method was used to investigate the relationship between the p73 G4A polymorphism and the risk of breast cancer. Results: There was no significant association between the AA genotype of the p73 G4A polymorphism and breast cancer in case and control groups. Although G allele frequency was higher in the case group, the abundance of this allele between case and control groups was not statistically meaningful and, as a result, not associated with the risk of breast cancer in this study group. Conclusion: There was no association between G4A p73 polymorphism and the risk of breast cancer in a northeastern Iranian population.  

scholarly journals Factors of Incidence of Hypertension in Southwest Sumba

2020 ◽  
Vol 2 (2) ◽  
pp. 86-96
Author(s):  
Apliana Lupu Kaka ◽  
Johny A.R Salmun ◽  
Agus Setyo Budi
Keyword(s):  
Blood Pressure ◽  
Case Control ◽  
Smoking Habits ◽  
Observational Research ◽  
Control Group ◽  
Case Group ◽  
A Value ◽  
Control Research ◽  
And Control ◽  
The Relationship

Hypertension in conditions when blood pressure is at a value of 130/80 mmHg or more with the number of cases experiencing an increase from 2016-2018, Tana Mete Village, Kodi Balaghar District. in 2016 there were 880 (8.8%), cases in 2017 were 2,580 (25.8%) cases and in 2018 there were 3. 410 (34.1%) cases. Hypertension in influenced by factors of age, smoking habits, stress, and alcohol consumption. This study aims to analyze the relationship between age, smoking habits, stress, and alcohol comsuption. This research is an analytic observational research with a case control research design. The number of cases in Tana Mete Village, Kodi Balaghar District, Southwest Sumba Regency was 220 (22%) and the sample was 80 respondents and divided into two groups, namely the case and control group, the case group was 40 respondents and the control group was 40 respondents. These variables have been analyzed univariately and bivariately, the results of this study incidate that there are three risk factor variables for the incidence of hypertentsion. Namely age with a value p= 0.003, OR=4.059 (95% CI: 1.568-10.510), smoking habits with a value p=0.001, OR: 6.378 (95%CI:2.280-17.842), stress with a value of p=0.014, OR: 3.095 (95%CI: 3.095-7.706) while the variable alcohol comsumption has no relationship with the value of p=0.133. To prevent the occurrence of hypertension, the activities undertaken include avoiding smoking, stress and taking time for recreation.

scholarly journals HUBUNGAN KECUKUPAN VITAMIN C DAN ZAT BESI DENGAN KEBUGARAN JASMANI ATLET PENCAK IPSI LAMONGAN

2018 ◽  
Vol 12 (2) ◽  
pp. 134
Author(s):  
Kartika Indaswari Dewi ◽  
R. Bambang Wirjatmadi
Keyword(s):  
Vitamin C ◽  
Physical Fitness ◽  
Control Design ◽  
Case Control ◽  
Statistical Test ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
And Control ◽  
The Relationship

Pencak silat is a sport that requires agility, speed, balance and body slenderness. Vitamin C and iron are part of the micronutrients that can support the athlete’s physical fitness. The aims of this study was to determine the relationship between the adequacy of vitamin C and iron with physical fitness of pencak silat athletes IPSI Lamongan. This study used observational analytics with case-control design with 20 samples of athletes, divided into 10 cases and 10 controls. The result of analysis from 2×24 hour food recall method in each case group was 9 (90%) athletes did not meet the requirement of vitamin C (<77%) and 8 (80%) athletes did not meet the requirement of iron and control group there were 7 (70 %) Athletes are not sufficient for vitamin C (<77%) and 6 (60%) of athletes are inadequate for iron (<77%). From the statistical test using chi-square, it was found that there was no significant relationship between vitamin C and iron adequacy with physical fitness (TKJI) with p=0.580 and p=0.620. Conclusion: adequacy level of vitamin C and iron of pencak silat athletes IPSI Lamongan is not meet their requirement yet.

scholarly journals The study of Effective Factors on Breast Cancer in Ardabil

2021 ◽  
Vol 15 (7) ◽  
pp. 1991-1993
Author(s):  
Davoud Adham ◽  
Eslam Moradi-Asl, Malek Abazari
Keyword(s):  
Breast Cancer ◽  
Classification Tree ◽  
Control Group ◽  
Case Group ◽  
Effective Factors ◽  
Cancer Breast ◽  
High Prevalence ◽  
Tree Models ◽  
Keywords Cancer ◽  
And Control

Background: The prevalence of breast cancer is about one third of all cancers in women constitute the second most common cancer after lung cancer and the most common cause of cancer death among women. Because of high prevalence, study of effective factors on breast cancer in Ardabil area is a very important. Method: In this case-control study, 100 women were selected from the breast cancer clinic that referred to hospitals in the Ardabil city in 2014 year. In addition, 100 healthy women were that referred to health centers in Ardabil city, selected for cluster and were considered as the control group. For statistical analysis and investigation of the influencing factors on breast cancer used to classification tree models. Results: The analyses indicated that, 83 women from case group and 80 women from control group were married. The most common age for patients whit breast cancer was 15-49 years old with average 32/8 year and (SD= 8.3).40% of women whit breast cancer were less than 30 years. None of the women did not have breast secretions in the control groups but 43 women in case groups have breast secretions. Conclusion: The identification of risk factors in this study can be programmed to prevent and control breast cancer. Keywords: Cancer, Breast, Ardabil

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