Ultrasonic-assisted rapid extraction of Cassia sieberiana D.C.: a Box-Behnken design process optimisation

2021 ◽  
Vol 14 (1) ◽  
pp. 15
Author(s):  
Saidu Jibril ◽  
Hasnah Mohd Sirat ◽  
Norazah Basar ◽  
Roswanira Abdul Wahab ◽  
Naji A. Mahat ◽  
...  
Keyword(s):  
Design Process ◽  
Process Optimisation ◽  
Box Behnken Design ◽  
Rapid Extraction ◽  
Ultrasonic Assisted

Ultrasonic-assisted rapid extraction of Cassia sieberiana D.C.: a Box-Behnken design process optimisation

2021 ◽  
Vol 14 (1) ◽  
pp. 15
Author(s):  
Saidu Jibril ◽  
Hasnah Mohd Sirat ◽  
Norazah Basar ◽  
Roswanira Abdul Wahab ◽  
Naji A. Mahat ◽  
...  
Keyword(s):  
Design Process ◽  
Process Optimisation ◽  
Box Behnken Design ◽  
Rapid Extraction ◽  
Ultrasonic Assisted

scholarly journals Optimization of ultrasonic-assisted extraction of inulin from Jerusalem artichoke

2019 ◽  
Vol 78 ◽  
pp. 02007
Author(s):  
Lina Yang ◽  
Hongyun Zhang ◽  
Jinghang Huang ◽  
Yafan Zhao ◽  
Danshi Zhu ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Jerusalem Artichoke ◽  
Hot Water ◽  
Ultrasonic Power ◽  
Hot Water Extraction ◽  
Box Behnken Design ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction

An efficient ultrasonic-assisted extraction of inulin from Jerusalem artichoke was investigated by Response Surface Methodology (RSM). The results showed that the yield of ultrasonic-assisted extraction was 62.07 ± 0.39% over the microwave (40.85 ± 0.28%) and hot water extraction (27.42 ± 0.42%). The Box-Behnken Design (BBD) was used to optimize the effects of three parameters (temperature-X1, ultrasonic power-X2 and time-X3) on inulin yield. Analysis of variance showed that the contributions of X1, X3, X12, X13, X22 were significant. The optimal yield of inulin was 82.93 ± 1.03% at 82 °, 120 W and 18 min.

scholarly journals Green and Efficient Extraction of Resveratrol from Peanut Roots Using Deep Eutectic Solvents

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Jingnan Chen ◽  
Xingxing Jiang ◽  
Guolong Yang ◽  
Yanlan Bi ◽  
Wei Liu
Keyword(s):  
Choline Chloride ◽  
Deep Eutectic Solvents ◽  
Extraction Yield ◽  
Box Behnken Design ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Efficient Extraction ◽  
Ultrasonic Assisted Extraction ◽  
Solid Liquid ◽  
Total Extraction

Deep eutectic solvents (DESs), a new group of ecofriendly solvent combined with the ultrasonic-assisted extraction (UAE) technique, were first successfully used for extraction of resveratrol from peanut roots. Resveratrol in the extract was analyzed and quantified using a HPLC-UV method. A series of DESs consisting of choline chloride (ChCl) and 1,4-butanediol, citric acid, and ethylene glycol were formulated, finding ChCl/1,4-butanediol was a most proper extraction system. The optimal extraction parameters were obtained using a Box–Behnken design (BBD) test combined with response surface methodology as follows: 40% of water in ChCl/1,4-butanediol (1/3, g/g) at 55°C for 40 min and solid/liquid ratio of 1:30 g/mL. The total extraction content and extraction yield of resveratrol from peanut roots could reach 38.91 mg/kg and 88.19%, respectively, under such optimal conditions. The present study will provide a typical example for using DESs to extract natural bioactive compounds from plants.

Optimizing the Conditions for Polysaccharides Ultrasonic-Assisted Extraction in Mycelium of Paecilomyces Tenuipes Pt196 Using Statistical Approach

2013 ◽  
Vol 756-759 ◽  
pp. 180-185
Author(s):  
Lin Na Du ◽  
Wen Ting Bu ◽  
Wen Lin Pan ◽  
Chen Shao ◽  
Jia Hui Lu ◽  
...  
Keyword(s):  
Neural Network ◽  
Genetic Algorithm ◽  
Artificial Neural Network ◽  
Ultrasonic Power ◽  
Box Behnken Design ◽  
Solid Ratio ◽  
Assisted Extraction ◽  
Ultrasonic Time ◽  
Ultrasonic Assisted ◽  
Artificial Neural

In order to enhance the extraction rate of polysaccharides, a series of statistical approach was used to optimize the ultrasonic-assisted extraction conditions from the mycelium of Paecilomyces tenuipes Pt196. [Metho The optimization of conditions was carried out in two stages. Firstly, the effects of various experimental parameters considered for the investigation (ultrasonic power, ultrasonic time and liquid-solid ratio) were studied using the method of single factor test design experiments. Secondly, a 15-run Box-Behnken design was performed to optimize the extraction conditions of polysaccharides. The experimental results of Box-Behnken design were analyzed by response surface methodology and artificial neural network together with genetic algorithm. [Result The optimum conditions for polysaccharides extraction obtained by the application of artificial neural network-genetic algorithm were ultrasonic time 345s, ultrasonic power 320 W and liquid-solid ratio 95 mL·g-1. [Conclusion Artificial neural network-genetic algorithm can effectively select the best extraction conditions of polysaccharides in this study.

scholarly journals Extraction Optimization of 5,7-Dihydroxy-6,8,4′-trimethoxyflavonol, a Bioactive Flavonoid from Rubus rosifolius (Rosaceae) Leaves

2019 ◽  
Vol 14 (1) ◽  
pp. 1934578X1901400
Author(s):  
Janieire Lorraine da Rocha Pittarello ◽  
Marcel Petreanu ◽  
Valdir Cechinel Filho ◽  
Clóvis Antonio Rodrigues ◽  
Luiz Carlos Klein-Júnior ◽  
...  
Keyword(s):  
Extraction Method ◽  
High Performance ◽  
Solvent Ratio ◽  
Flavonoid Content ◽  
Box Behnken Design ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
Addition Level

Recently, it has been demonstrated that a rare flavonoid, 5,7-dihydroxy-6,8,4′-trimethoxyflavonol (1), isolated from the leaves of Rubus rosifolius showed significant antiproliferative activity against different cancer cell lines and had a diuretic effect. This study aimed to determine the best extraction method evaluating dynamic maceration extraction (DME), ultrasonic assisted extraction (UAE), and microwave assisted extraction (MAE). In addition, level optimization for different factors was focused using Design of Experiments. The flavonoid content was estimated by high performance liquid chromatography (HPLC). The results indicated that UAE provided the highest content with the shortest extraction time. For optimization, response surface methodology (RSM) was used, applying a Box-Behnken Design (BBD) with three factors at three levels. It was possible to observe that the flavonoid content significantly increased with the increase of temperature (max. 70°C). The time had little influence on the extraction and, for this reason, was set at 25 min. With regard to the drug/solvent ratio, it was observed that this had an impact on yield with a ratio of 3.5%. A model was built and a determination coefficient of 0.98 was obtained. After validation, an optimized method was developed, able to extract 1 with a lower time, lower solvent consumption, and affording higher contents.

Extraction and Antioxidant Activity of Ultrasonic-Assisted Flavonoids from Suaeda salsa

2011 ◽  
Vol 140 ◽  
pp. 343-349 ◽  
Author(s):  
Lei Guo ◽  
Chao Liu
Keyword(s):  
Suaeda Salsa ◽  
Ultrasonic Power ◽  
Extraction Temperature ◽  
Dpph Radical ◽  
Liquid Ratio ◽  
Box Behnken Design ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction ◽  
Dose Dependent

The box-behnken design combined with response surface methodology was used to optimize ultrasonic-assisted extraction of flavonoids from Suaeda salsa (Linn.) Pall. The results indicate that the highest extraction rate of flavonoids by ultrasonic-assisted extraction could arrive 5.17% using 500W ultrasonic power, 69% ethanol as solvent, 77°C extraction temperature, 1:40 solid to liquid ratio for 58 min extraction. The flavonoids-enriched extracts exhibited quite strong reducing property and excellent inhibitions of DPPH radical, hydroxyl radical. Meanwhile, it was found that the bioactivities appeared to be dose-dependent of flavonoids.

scholarly journals Coupling Ultrasound with Heat-Reflux to Improve the Extraction of Quercetin, Kaempferol, Ginkgetin and Sciadopitysin from Mairei Yew Leaves

2019 ◽  
Vol 9 (4) ◽  
pp. 795
Author(s):  
Chunjian Zhao ◽  
Xueting Ren ◽  
Chunying Li ◽  
Hongwei Jiang ◽  
Jiajing Guan ◽  
...  
Keyword(s):  
Total Yield ◽  
Maximum Yield ◽  
Extraction Time ◽  
High Yield ◽  
Ultrasonic Power ◽  
Box Behnken Design ◽  
Extraction Solvent ◽  
Solid Ratio ◽  
Assisted Extraction ◽  
Ultrasonic Assisted

The coupling of ultrasound and heat–reflux extraction (UHRE) was developed for separation for quercetin (QU), kaempferol (KA), ginkgetin (GI) and sciadopitysin (SC) from Mairei Yew leaves. The Box–Behnken design was used to optimize the UHRE conditions for obtaining the maximum yield of flavonoids. The optimal extraction conditions were as follows: boiling 80% methanol (V/V) for extraction solvent, 20 min for the extraction time, 200 W for the ultrasonic power and 26 mL/g for the liquid–solid ratio. By UHRE, the yields of QU, KA, GI and SC were, respectively, 0.109, 0.406, 0.031 and 0.355 mg/g, and total yield of four flavonoids was 0.901 mg/g, which were, respectively, 1.25-fold and 1.23-fold higher than those by using ultrasonic-assisted extraction (UAE) and heating reflux extraction (HRE). Moreover, the extraction time for the equilibrium yields of flavonoids using UHRE was 83.3% and 27.8%, respectively, less than the corresponding time using UAE and HRE. Compared with HRE and UAE, UHRE showed the increase of cell disruption degree as observed by scanning electron microscopy, which may be the reason for high yield and rapid extraction of target compounds.

scholarly journals Optimization of Ultrasound-Assisted Emulsification of Emollient Nanoemulsions of Seed Oil of Passiflora edulis var. edulis

Cosmetics ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Caterine Guzmán ◽  
Maritza Adelina Rojas ◽  
Marcela Aragón
Keyword(s):  
Food Industry ◽  
Seed Oil ◽  
Irradiation Time ◽  
Considerable Improvement ◽  
Ultrasonic Power ◽  
Passiflora Edulis ◽  
Box Behnken Design ◽  
Food Industries ◽  
Ultrasonic Assisted ◽  
Formulation Variables

Passiflora edulis var. edulis is a plant of commercial interest because of it fruits. The seeds, a by-product in the food industry, can be a source of oil for cosmetic, pharmaceutical and food industries. The aims of this work were to optimize the ultrasonic-assisted emulsification conditions for o/w nanoemulsions and to evaluate the emollient activity of the seed oil. The optimum emulsification conditions were established, using the response surface methodology with a Box-Behnken design (BBD). The emollient activity of seed oil of P. edulis var. edulis was evaluated with healthy volunteers using a cutometer for skin moisture and viscoelasticity measurements. The optimal formulation variables (85.34 W of ultrasonic power, 5.96 irradiation time, 70.65% water and a 5:4 oil:surfactant ratio), resulted in considerable improvement in the properties of the ultrasonically formulated nanoemulsions. Finally, the seed oil of P. edulis var. edulis and the nanoemulsion generated by ultrasound presented emollient activity.

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