An efficient fluorimetric method to measure the viability of intraerythrocytic Plasmodium falciparum
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AbstractA range of various assays to measure chemosusceptibility ofPlasmodium falciparumhave been described in the literature. As the screening of a plethora of compounds for antiplasmodial activity is urgently needed and becomes a constantly increasing routine analysis, a test system has to fulfill the following requirements: sensitivity, reliability, simplicity of performance, high-throughput compatibility, and cost-effectiveness. Here, we describe an assay that fulfills all criteria and in which the fluorescent SYTOX®Green dye is introduced to determine growth inhibition ofPlasmodiainin vitrocultures.
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2012 ◽
Vol 2
(3)
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pp. 180-183
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2006 ◽
Vol 50
(4)
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pp. 1586-1589
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2004 ◽
Vol 133
(2)
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pp. 267-274
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