scholarly journals Assessment of Oral and Periodontal Parameters in Patients with End-Stage Chronic Kidney Disease

2015 ◽  
Vol 19 (3) ◽  
pp. 153-157
Author(s):  
Sorina Solomon ◽  
Irina Ursarescu ◽  
Liliana Pasarin ◽  
Ionut Nistor ◽  
Gabriel Veisa ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Oral Cavity ◽  
Arterial Hypertension ◽  
Tooth Loss ◽  
Close Link ◽  
Associated Diseases ◽  
Medical Histories ◽  
End Stage

SummaryAim: The purpose of the study was to assess the oral cavity status in patients with terminal chronic kidney disease (CKD) undergoing haemodialysis.Materials and Methods: The study comprised 69 patients with end-stage CKD undergoing haemodialysis regime. The data regarding the age, gender, environment, associated diseases were obtained from the clinical medical histories. The patients were submitted to clinical examination, which also included the periodontal probing and the gingival bleeding assessment. The type of edentulous ridge was recorded. Each patient filled a questionnaire offering data regarding the oral hygiene habits, diet, bad habits and the presence/absence of xerostomia.Results and Discussion: The main cause for end-stage CKD was renal, followed by diabetes mellitus and arterial hypertension. The main associated diseases to CKD were clearly secondary arterial hypertension and secondary anaemia; other associated diseases were represented by cardiac diseases, hepatitis, gastro-intestinal diseases, secondary hyperparathyroidism, cirrhosis, hypersplenism, epilepsy and neoplastic diseases. 62.31% of the patients accused frequent xerostomia. When recording the edentulous type, we observed a high percentage of complete tooth loss.Conclusions: There is a close link between the systemic changes in the CKD patient and the oral manifestations. Even 2 of the main causes of CKD (hypertension and diabetes mellitus) exert important changes on the tissues in the oral cavity, leading to significant tooth loss and masticatory impairment, thus, to a poor quality of life.

scholarly journals Stroke risk factors in patients with end-stage kidney disease: current status of the problem

2020 ◽  
Vol 101 (6) ◽  
pp. 825-833
Author(s):  
I T Murkamilov ◽  
K A Aitbaev ◽  
V V Fomin ◽  
Zh A Murkamilova ◽  
F A Yusupov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Heart Failure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arterial Hypertension ◽  
Bone Mineral ◽  
End Stage Kidney Disease ◽  
Common Risk Factors ◽  
End Stage

Chronic kidney disease and its complications are one of the leading causes of morbidity, disability and mortality in the world population, due to both the widespread prevalence of arterial hypertension, diabetes mellitus and coronary heart disease, and the increase in life expectancy. In the terminal stage of chronic kidney disease, mortality from cardiovascular events increases significantly. This review examines the most common risk factors for stroke in end-stage kidney disease. The role of arterial hypertension, diabetes mellitus, chronic heart failure is discussed, taking into account common risk factors, hyperactivation of the renin-angiotensin-aldosterone system, the development of oxidative stress, volume overload with an increase in the size of the left atrium and a subsequent increase in the risk of thrombosis and stroke in patients with end-stage kidney disease on programmed hemodialysis. In addition, data are presented in the study of the contribution of bone mineral disorders to the occurrence of cerebral complications in this category of patients. Timely diagnosis of cardiovascular diseases and secondary prevention of stroke, including adequate antihypertensive, hypoglycemic therapy and correction of heart failure with blockers of the renin-angiotensin-aldosterone system, as well as the elimination of bone mineral disorders are currently a very popular approach to improving the quality of life and increased survival in the discussed category of patients. Understanding the pathogenetic mechanism of stroke in patients with end-stage kidney disease on programmed hemodialysis, with the study of risk factors in the development of an acute cerebrovascular accident, will help to develop a strategy for their management.

scholarly journals The risk of chronic kidney disease and diabetes mellitus in patients with arterial hypertension

2017 ◽  
Vol 0 (2(70)) ◽  
pp. 51-54 ◽  
Author(s):  
В. С. Джуряк ◽  
І. В. Бондарчук ◽  
Л. П. Сидорчук ◽  
М. М. Сем’янів ◽  
Ю. В. Репчук ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arterial Hypertension

P0737THE ASSOCIATION BETWEEN CYSTATIN C AND ARTERIAL STIFFNESS IN NON-CKD PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Nejc Piko ◽  
Tadej Petreski ◽  
Robert Ekart ◽  
Radovan Hojs ◽  
Sebastjan Bevc
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Myocardial Perfusion ◽  
Arterial Stiffness ◽  
Arterial Hypertension ◽  
Cystatin C ◽  
Laboratory Data ◽  
Applanation Tonometry ◽  
Serum Cystatin C

Abstract Background and Aims Serum cystatin C (cysC) is produced by all nucleated cells at a constant rate, is filtered freely by the glomerulus and metabolized after tubular reabsorption. It is influenced less by age, gender and muscle mass compared to serum creatinine. These properties make it an important marker in detecting renal impairment. Arterial stiffness is a hallmark of atherosclerosis and is connected to cardiovascular events and mortality. In patients with chronic kidney disease (CKD), cysC correlates with increased arterial stiffness, but less is known about the association between cysC and arterial stiffness in non-CKD patients. Method The study was performed at the University Medical Centre Maribor between October 1st 2018 and January 1st 2020. Basic demographic and laboratory data were recorded. To estimate glomerular filtration rate (eGFR), Chronic Kidney Disease Epidemiology (CKD-EPI) equation was used. Patients with previously diagnosed CKD and/or eGFR ≤ 60 ml/min/1.73m2 at the time of admission, known malignancy, thyroid disease and/or on steroid therapy were not enrolled in the study. Arterial stiffness was measured with applanation tonometry (Sphygmocor®, Australia), carotid-femoral pulse wave velocity (cfPWV) was used as the gold standard of central arterial stiffness and subendocardial viability ratio (SEVR) was used as the marker of myocardial perfusion. SPSS® version 22 was used for statistical analysis. Results 111 patients (65.8% male, average age 64.3±9.4 years) were included in our study. Most common comorbidities were arterial hypertension (n=86, 77.5%), hyperlipidaemia (n=64, 57.7%) and diabetes mellitus (n=22, 19.8%). Mean creatinine value was 77.7±13.8 μmol/L (range 49-108 μmol/L), mean eGFR was 81.3±9.4 ml/min/1.73m2 (range 62-90 ml/min/1.73m2) and mean value of cysC was 0.94±0.18 mg/L (range 0.67-1.63 mg/L). Mean SEVR value was 165.7±36.1% (range 92-299%) and mean cfPWV value was 10.1±2.4 m/s (range 6.2-16.8 m/s). Significant correlation was found between cysC and SEVR (r=-0.316, p<0.001) and between cysC and cfPWV (r=0.472, p<0.001). Multiple regression analysis of arterial stiffness indices and cysC, age, gender, diabetes mellitus, arterial hypertension, eGFR and hyperlipidemia, showed statistically significant association between cysC and cfPWV (ß=0.220, p=0.038) and cysC and SEVR (ß=-0.278, p=0.017). Conclusion Serum cysC is independently associated with increased arterial stiffness, reduced myocardial perfusion and increased cardiovascular risk in non-CKD patients.

scholarly journals Prevalence of chronic kidney disease in Brazilians with arterial hypertension and/or diabetes mellitus

2020 ◽  
Vol 22 (9) ◽  
pp. 1666-1673
Author(s):  
Luma de Oliveira Comini ◽  
Laura Camargo Oliveira ◽  
Luiza Delazari Borges ◽  
Heloísa Helena Dias ◽  
Clara Regina Santos Batistelli ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arterial Hypertension

Gingivitis, increased probing depth, clinical attachment loss and tooth loss among patients with end-stage chronic kidney disease: a case-control study

2017 ◽  
Vol 26 (1) ◽  
pp. 75-80
Author(s):  
Iana T. Parente ◽  
Zaira R. Lima ◽  
Luzia Hermínia Teixeira ◽  
Mario R. Lisboa ◽  
Iracema M. de Melo ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Tooth Loss ◽  
Case Control Study ◽  
Case Control ◽  
Clinical Attachment Loss ◽  
Attachment Loss ◽  
Probing Depth ◽  
End Stage ◽  
Control Study

scholarly journals Adropin and irisin in arterial hypertension, diabetes mellitus and chronic kidney disease

2019 ◽  
Vol 28 (11) ◽  
pp. 1571-1575 ◽  
Author(s):  
Magdalena Maciorkowska ◽  
Dominika Musiałowska ◽  
Jolanta Małyszko
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arterial Hypertension

scholarly journals Metformin: From Immediate Release to Extended Release Formula, Effectiveness, And Safety in Patients With Chronic Kidney Disease

EMJ Diabetes ◽  
2020 ◽  
pp. 70-78
Author(s):  
Giuseppe Derosa ◽  
Rodolfo Rivera ◽  
Angela D'Angelo ◽  
Pamela Maffioli
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Type 2 Diabetes Mellitus ◽  
Kidney Disease ◽  
Immediate Release ◽  
The World ◽  
Stage Renal Disease ◽  
End Stage

Type 2 diabetes mellitus is currently the main cause of chronic kidney disease, leading to end-stage renal disease in most countries around the world. Metformin is the most commonly prescribed oral antihyperglycaemic in the world and after approval by the U.S. Food and Drug Administration (FDA) in 1994, it is currently recommended as the first-line pharmacological agent for newly diagnosed Type 2 diabetes mellitus by many professional diabetes associations. In this review, the authors analysed efficacy and safety of metformin in patients with chronic kidney disease.

scholarly journals COMPLICACIONES POR HEMODIÁLISIS EN UN HOSPITAL DE LA CIUDAD MACHALA, ECUADOR

2021 ◽  
Vol 6 (2) ◽  
pp. 12
Author(s):  
Elida Reyes Rueda ◽  
Jorge Armando García Maldonado ◽  
Carmen Liliana Paccha Tamay ◽  
Sara Esther Vera Quiñonez ◽  
Janeth Del Rosario Rodríguez Sotomayor
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Kidney Disease ◽  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Arterial Hypertension ◽  
Replacement Therapy ◽  
Adult Population ◽  
Common Factor ◽  
Public Health Problem ◽  
Validated Questionnaire

Introducción: La hemodiálisis constituye un tipo de terapia renal sustitutiva, indicado en los pacientes con Enfermedad renal crónica (ERC). Estas constituyen un problema de salud pública, afectando al 10% de la población adulta. Producto de enfermedades crónicas no transmisibles (ECNT) como la hipertensión arterial (HTA) o la diabetes mellitus (DM) entre otros. Objetivo: Identificar las complicaciones durante el tratamiento de hemodiálisis en pacientes con ERC. Métodos: Estudio descriptivo, transversal, muestra de 57 pacientes, mayores de 30 años; Se utilizó un cuestionario validado para recoger la información. Resultados: Los pacientes con hemodiálisis son mayores de 61 años en 33% de los casos; del género masculino en 51%. Con hemodiálisis por más de 19 meses el 72%. Complicados vértigos 47% de los casos, un 30% sin complicaciones y con un 5% hipertermia y taquipnea respectivamente. Con comorbilidades combinadas como diabetes+HTA+glomerulonefritis en un 19%; HTA+glomerulonefritis 18% y aisladamente glomerulonefritis en un 16%. Conclusiones: Existe un predominio del sexo masculino, mayores de 61 años en pacientes que reciben hemodiálisis.  Con comorbilidades combinadas como glomerulonefritis con hipertensión arterial y diabetes. Seguido de la combinación glomerulonefritis con hipertensión arterial y en tercer lugar glomerulonefritis aislada. Observándose que el factor común es la glomerulonefritis. La complicación más frecuente fue el vértigo, seguido de ninguna complicación en casi el tercio de la muestra estudiada, un pequeño porcentaje presentó taquipnea, epistaxis, aisladas o combinadas. La socialización del autocuidado en pacientes con diabetes e HTA para evitar el desarrollo de la Enfermedad renal crónica, es la clave para su prevención  Palabras clave: hemodiálisis, terapia renal sustitutiva, enfermedad renal crónica  ABSTRACT Introduction: Hemodialysis is a type of renal replacement therapy, indicated in patients with chronic kidney disease (CKD). These constitute a public health problem, affecting 10% of the adult population. Product of chronic non-communicable diseases (CNCD) such as arterial hypertension (HT) or diabetes mellitus (DM) among others. Aim: Identify complications during hemodialysis treatment in CKD patients. Methods: Descriptive, cross-sectional study, sample of 57 patients, older than 30 years; A validated questionnaire was carried out to collect the information. Results: Hemodialysis patients are older than 61 years in 33% of cases; of the masculine gender in 51%. With hemodialysis for more than 19 months, 72%. Complicated vertigo in 47% of cases, 30% without complications and with 5% hyperthermia and tachypnea respectively. With combined comorbidities such as diabetes + hypertension + glomerulonephritis in 19%; HBP + glomerulonephritis in 18% and glomerulonephritis in isolation in 16%. Conclusions: There is a predominance of males, older than 61 years in patients receiving hemodialysis. With combined comorbidities such as glomerulonephritis with high blood pressure and diabetes. Followed by the combination of glomerulonephritis with arterial hypertension and thirdly isolated glomerulonephritis. Noting that the common factor is glomerulonephritis. The most frequent complication was vertigo, followed by no complication in almost a third of the sample studied, a small percentage presented tachypnea, epistaxis, isolated or combined. The socialization of self-care in patients with diabetes and hypertension to avoid the development of chronic kidney disease is the key to its prevention Key words: hemodialysis, renal replacement therapy, chronic kidney disease

scholarly journals Periodontal Treatment Needs of Hemodialized Patients

Healthcare ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 139
Author(s):  
Agata Trzcionka ◽  
Henryk Twardawa ◽  
Katarzyna Mocny-Pachońska ◽  
Marta Tanasiewicz
Keyword(s):  
Chronic Kidney Disease ◽  
Chronic Disease ◽  
Kidney Disease ◽  
Arterial Hypertension ◽  
Control Group ◽  
Treatment Needs ◽  
Periodontal Status ◽  
Periodontal Tissues ◽  
Saliva Secretion ◽  
End Stage

End-stage renal failure is the reason for complications in many systems and organs, and the applied pharmacotherapy often causes the deepening of already existing pathologies within the oral cavity, such as: caries, periodontal diseases, mucosal lesions or reduced saliva secretion. Reduced saliva secretion results in an increased accumulation of dental plaque, its mineralization and prolonged retention, which leads to the development of gingival and periodontal inflammation. There is some evidence that chronic kidney diseases are influenced by periodontal health. The aim of the work was to evaluate the dental needs by the usage of clinical assessment of periodontal tissues of patients suffering from end-stage chronic kidney disease, arterial hypertension or/and diabetes mellitus. Material and methods: 228 patients underwent the research. 180 patients were hemodialized in Diaverum dialysis stations (42 of them were diagnosed with end stage chronic disease, 79 with the end stage chronic disease and arterial hypertension, 16 with end stage chronic kidney disease and diabetes, 43 with end-stage chronic disease, arterial hypertension and diabetes) and 48 patients of the Conservative Dentistry with Endodontics Clinic of Academic Centre of Dentistry of Silesian Medical University in Bytom and patients of the dentistry division of Arnika Clinic in Zabrze not diagnosed with any of the aforementioned diseases. The scheme of the research comprised 2 parts: analysis of the general health and assessment of the periodontal status which contain the following indices: Periodontal Probing Depth (PPD), Clinical Attachment Lost (CAL), Bleeding Index or Bleeding on Probing Index (BI or BOP), Community Periodontal Index for Treatment Needs (CPITN). Results: Significantly lower percentage of patients with healthy periodontal tissues and higher percentage with periodontal pockets deeper than 3.5 mm and the loss of trainers connective of 5 mm or higher were in the examined group. The values of the bleeding index were significantly lower in control group. The analysis of the CPITN index indicates higher percentage of patients qualified as CPI 1 or 2 in the control group while in the examined one most of the patients turned out to require specialist periodontal treatment. Conclusions: there is a direct relationship between periodontal status and end-stage renal disease which typically includes other chronical civilization ailments. It is important to develop a scheme for the easy and rapid examination of periodontal status, to determine the treatment needs in this area, which will allow precise assignment of long-term dialyzed patients to the range of prophylactic and therapeutic procedures.

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