In this study, wheat-straw lignocelluloses were liquefied in liquefaction solvents. Polyethyleneglycol 400 (PEG 400) and ethylene glycol (EG) were used as main liquefaction solvents. The effect of liquefaction time and liquefaction solvents on the properties of liquefied products was investigated. As the reaction time increased, the hydroxyl value, residue content and viscosity decreased, and the acid value decreased gradually in the previous period of time then increased. The optimum liquefaction conditions were as follows: wheat-straw lignocelluloses with steam-explosion pretreatment, the main liquefaction reagent of PEG 400, auxiliary liquefaction solvents of glycerin, catalyst of sulfuric acid, liquefaction temperature of 150°C, liquefaction time of 4 h. The hydroxyl value of liquefaction product was 206 mgKOH/g, the residue content was 0.19% and the viscosity was 88 mPa•s.