The concordance between ultrasonographic stage of breast and Tanner stage of breast for overweight and obese girls: a school population-based study

Author(s):  
Dongxue Pan ◽  
Simao Fu ◽  
Xiaoqing Li ◽  
Tingting Yu ◽  
Sizhe Huang ◽  
...  

Abstract Objectives In this study, we evaluated the concordance between the ultrasonographic stage of breast (US B) and Tanner stage of breast (TS B) for overweight and obese girls based on a school population study. Methods We conducted multistage, stratified cluster, and random-proportional sampling and ultimately included 221 girls (aged 6–10 years). Results This study revealed that the concordance was poor (accuracy=0.19 (95% confidence interval: 0.14, 0.25)) between US B and TS B among the 221 participants. When our subjects were stratified by weight, we observed a weak association between US B and TS B in the thin/normal weight group (r=0.34, p=0.001) but not in the overweight (r=0.097, p=0.38) or obese groups (r=–0.19, p=0.206), and as the body mass index (BMI) z-score increased, the overestimation ratio of TS B increased. US B manifested a positive correlation with breast bud diameter (BD) (r=0.885, p<0.001), follicle-stimulating hormone (r=0.235, p=0.009), and luteinizing hormone (r=0.192, p=0.037), but this was not the case with TS B. Conclusions As the BMI z-score increased, the correlation between the two methods declined, and the overestimation ratio of TS B increased. US B is an objective and quantitative method used to evaluate breast development, and whether BD might replace US B as a routine diagnostic method to evaluate breast development in clinical practice needs to be confirmed in larger-sample studies.

2021 ◽  
pp. 1-4
Author(s):  
Oscar H. Del Brutto ◽  
Robertino M. Mera

A total of 590 older adults of Amerindian ancestry living in rural Ecuador received anthropometric measurements and a brain magnetic resonance imaging to estimate the total cerebral small vessel disease (cSVD) score. A fully adjusted ordinal logistic regression model, with categories of the total cSVD score as the dependent variable, disclosed significant associations between the waist circumference, the waist-to-hip, and the waist-to-height ratios – but not the body mass index (BMI) – and the cSVD burden. Indices of abdominal obesity may better correlate with severity of cSVD than the BMI in Amerindians. Phenotypic characteristics of this population may account for these results.


Endocrine ◽  
2021 ◽  
Author(s):  
Yifan Liu ◽  
Tingting Yu ◽  
Xiaoqing Li ◽  
Dongxue Pan ◽  
Xin Lai ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Tara Bharucha ◽  
Andrew M Davis ◽  
Christian Turner ◽  
Robert Justo ◽  
Terry Robertson ◽  
...  

Introduction Better data regarding the incidence and risk factors for sudden cardiac death (SCD) in children with cardiomyopathy (CM) is critical in defining appropriate primary prevention strategies. Methods The National Australian Childhood Cardiomyopathy Study is a prospective cohort study, including all children in Australia with primary CM diagnosed at 0 – 10 years of age, between 1987–1997. SCD was defined as sudden and unexpected death in children who were not hospitalized and not in congestive heart failure at the time of death. Nine subjects with sudden death as presenting symptom were excluded. Indexed echocardiographic measurements at latest follow-up were compared between subjects with SCD and survivors. Results Study criteria were met by 291 children. Mean duration of follow-up was 9.2 years. The incidence of sudden death relative to each CM type, for all cases and as a proportion of deaths, is shown in the Table : Incidence of SCD by CM type. SCD incidence was significantly associated with CM type, for all cases ( p = 0.006) and when only those subjects who died were considered ( p = 0.005), with LVNC and RCM having up to 4 times the risk of other CM types. Children with familial DCM had a significantly higher rate of SCD than subjects with non-familial CM (12% vs 3%; p = 0.028), however, familial CM was not a risk factor in other CM types. DCM SCD subjects had larger LVEDd Z score than survivors (median 5.53 vs 1.16; p <0.0001) and lower FS Z score (median −9.23 vs −0.51; p = 0.0025). HCM SCD subjects had thicker LVPW dimension Z scores than survivors (median 4.63 vs 1.18; p = 0.007). Twelve subjects (2 DCM, 8 HCM and 2 LVNC) underwent ICD implantation (8/12 for primary prevention). Conclusions: This population based study defines new risk factors for sudden death in children with CM. RCM is well known to have a high incidence of SCD. In addition, children with LVNC and those with DCM who have severe dilatation, systolic dysfunction or familial DCM are at increased risk of sudden death.


2018 ◽  
Vol 25 (5) ◽  
pp. 364-371 ◽  
Author(s):  
Rakhi Dandona ◽  
G Anil Kumar ◽  
Sibin George ◽  
Amit Kumar ◽  
Lalit Dandona

BackgroundWe report on incidence of drowning deaths and related contextual factors in children from a population-based study in the Indian state of Bihar which estimated the causes of death using verbal autopsy (VA).MethodsInterviews were conducted for deaths in 1–14 years population that occurred from January 2012 to March 2014 in 109 689 households (87.1% participation) in 1017 clusters representative of the state. The Population Health Metrics Research Consortium shortened VA questionnaire was used for interview and cause of death was assigned using the SmartVA automated algorithm. The annualised unintentional drowning death incidence, activity prior to drowning, the body of water where drowning death had occurred and contextual information are reported.FindingsThe survey covered 224 077 children aged 1–14 years. Drowning deaths accounted for 7.2%, 12.5% and 5.8% of all deaths in 1–4, 5–9 and 10–14 years age groups, respectively. The adjusted incidence of drowning deaths was 14.3 (95% CI 14.0 to 14.7) per 100 000 children, with it being higher in urban (16.1, 95% CI 14.8 to 17.3) areas. Nearly half of the children drowned in a river (5.9, 95% CI 5.6 to 6.1) followed by in a pond (2.8, 95% CI 2.6 to 2.9). Drowning death incidence was the highest while playing (5.1, 95% CI 4.9 to 5.4) and bathing (4.0, 95% CI 3.8 to 4.2) with the former accounting for more deaths in 1–4 years age group. Sixty per cent of children were already dead when found. None of these deaths were reported to the civil registration system to obtain death certificate.InterpretationThe findings from this large representative sample of children document the magnitude of and variations in unintentional drowning deaths in Bihar. Urgent targeted drowning interventions are needed to address the risk in children. Gross under-reporting of drowning deaths in children in India needs attention.


2010 ◽  
Vol 38 (6) ◽  
pp. 587-596 ◽  
Author(s):  
Lena M. Hansson ◽  
Erik Näslund ◽  
Finn Rasmussen

Aims: We examined whether men and women with obesity reported different types of discrimination to a greater extent than those with normal weight, and explored whether these associations were modified by socioeconomic position. Method: National representative sample of men and women, with normal weight (n = 2,000), moderate obesity (n = 2,461) and severe obesity (n = 557). Participants were identified in a yearly population-based survey (1996—2006) and data on perceived discrimination and potential confounding factors were measured in 2008. Logistic regression models tested whether obesity was associated with perceived lifetime, workplace, healthcare and interpersonal discrimination. Results: The overall response rate was 56%. For men, moderate obesity was associated with workplace discrimination, while severely obese women were more likely to report this sort of discrimination than normal weight women. Severely obese individuals were twice as likely to report healthcare discrimination than normal weight individuals. Women, regardless of weight status group, were in turn twice as likely to report healthcare discrimination as men. Women with severe obesity were significantly more likely to report interpersonal discrimination compared with normal weight women. Socioeconomic position modified the association between weight status and healthcare discrimination. Highly educated individuals with moderate and severe obesity were more likely to report healthcare discrimination than their normal weight counterparts, whereas low educated individuals with normal weight, moderate and severe obesity were equally likely to report discrimination. Conclusions: In this large, population-based study, discrimination was more likely to be reported by obese individuals compared with those of normal weight. The associations, however, varied according to gender and socioeconomic position.


Author(s):  
Camilo L. M. Lourenço ◽  
Venicius Dantas Da Silva ◽  
Edmar Lacerda Mendes

<p>Objetivo: estimar la prevalencia y los factores asociados con una actividad física insuficiente (AFI) en el tiempo libre entre los adolescentes de una ciudad mediana en el estado de Minas Gerais, Brasil. Métodos: Los datos de la encuesta transversal ACtVU (Uberaba - MG, Brasil) realizada entre mayo y octubre de 2015. Los estudiantes de secundaria de ambos sexos (de 14 a 18 años) comprendieron la muestra. AFI (&lt;300 minutos/semana) fue la variable dependiente y los indicadores sociodemográficos, de comportamiento y de salud fueron las variables independientes evaluadas mediante cuestionarios. Se utilizó la regresión logística binaria para estimar la Odds Ratio (OR). El IMC se utilizó como variable de control. Resultados: 984 estudiantes participaron en este estudio. El porcentaje de AFI fue del 44,9% (IC95%: 41,7; 48,1) y fue mayor entre las niñas (57,1% frente al 29,3% en los niños). Se encontró una mayor probabilidad de AFI en: la calificación para ambos sexos (OR = 2.23 niños, OR = 2.28 niñas), tiempo de pantalla entre semana (OR = 1.29), uso excesivo de teléfonos inteligentes durante la semana (OR = 1.54) y los fines de semana (OR = 1.22) entre niños, que estudian esta noche (OR = 1.80), que tienen un trabajo (OR = 1.24), ingresos familiares (OR = 1.41 para 3 a 5 salarios mínimos y OR = 1.65 para ≥ 6 salarios mínimos), tiempo de pantalla entre semana (OR = 1.87) e insatisfacción con el propio peso (OR = 1.32) entre las niñas. Conclusión: la prevalencia de AFI fue alta. La mayoría de los factores asociados fueron diferentes en niños y niñas.</p>


2021 ◽  
Vol 10 (16) ◽  
pp. 3758
Author(s):  
Seung-Woo Yang ◽  
Min-Jeong Oh ◽  
Keon-Vin Park ◽  
Sung-Won Han ◽  
Hee-Sun Kim ◽  
...  

Preeclampsia (PE) is a major disease of pregnancy, with various short- or long-term complications for both the mother and offspring. We focused on the body mass index (BMI) of offspring and compared the incidence of obesity during early childhood between PE- and non-PE-affected pregnancies. Women with singleton births (n = 1,697,432) were identified from the Korea National Health Insurance database. The outcomes of offspring at 30–80 months of age were analyzed. The effects of PE on BMI and the incidence of obesity in the offspring were compared. The incidence of low birth weight (LBW) offspring was higher in the PE group (n = 29,710) than that in the non-PE group (n = 1,533,916) (24.70% vs. 3.33%, p < 0.01). However, BMI was significantly higher in the PE-affected offspring than that in non-PE-affected offspring. After adjusting for various factors, the risk of obesity was higher in the PE-affected offspring (odds ratio = 1.34, 95% confidence interval = 1.30–1.38). The BMI and incidence of obesity were higher during early childhood in the PE-affected offspring, even though the proportion of LBW was higher. These results may support the basic hypotheses for the occurrence of various cardiovascular and metabolic complications in PE-affected offspring. In addition, early-age incidence of obesity could influence PE management and child consultation in clinical applications.


2013 ◽  
Vol 28 (suppl 4) ◽  
pp. iv130-iv135 ◽  
Author(s):  
E. Cohen ◽  
A. Fraser ◽  
E. Goldberg ◽  
G. Milo ◽  
M. Garty ◽  
...  

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