scholarly journals Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health

Pteridines ◽  
2018 ◽  
Vol 29 (1) ◽  
pp. 124-163 ◽  
Author(s):  
Hina Makkar ◽  
Mark A. Reynolds ◽  
Abhishek Wadhawan ◽  
Aline Dagdag ◽  
Anwar T. Merchant ◽  
...  

AbstractPrevious evidence connects periodontal disease, a modifiable condition affecting a majority of Americans, with metabolic and cardiovascular morbidity and mortality. This review focuses on the likely mediation of these associations by immune activation and their potential interactions with mental illness. Future longitudinal, and ideally interventional studies, should focus on reciprocal interactions and cascading effects, as well as points for effective preventative and therapeutic interventions across diagnostic domains to reduce morbidity, mortality and improve quality of life.

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Marini ◽  
A Masini ◽  
P Maietta Latessa ◽  
T Sanna ◽  
A Raggi ◽  
...  

Abstract Background Osteoporosis is a major health burden worldwide and require a multi-modal approach including exercise. Fractures have a substantial impact on quality of life (QoL) so exercise programs may to be conducted by trainers able to deal with this condition, because exercise alone, even if in the right dosage, seems to be not enough to improve QoL. A quasi-experimental pilot study performed to determine the feasibility and safety of an Adapted Physical Activity (APA) protocol specifically designed for osteoporotic women with vertebral fractures and its effect on QoL, with a specific focus on trainer's role. Methods The Experimental Group (EG) performed APA protocol 1hour twice a week for 6 months, while the Control Group (CG) received standard care. QoL was assessed at baseline and follow-up with ECOS-16 questionnaire and semi structured interviews to understand women perceptions regarding trainer's role. Using mixed-methods quantitative and qualitative data were analyzed using SPSS 5 and NVivo 12, respectively. Results 40 post-menopausal women (mean age: 67.6±4.6) divided in 2 groups EG = 22 and CG = 18, completed the study. At follow-up, EG improved significantly QoL (EG: -0.5±0.5 vs CG: 0.0±0.3 p = 0.02). The APA intervention had a significant effect on all the components of QoL, as measured by the disease-specific ECOS-16 questionnaire: Physical Component Summary (PCS) (EG: -0.4±0.5 vs CG: 0.0±0.4 p = 0.06) and Mental Component Summary (MCS) (EG: -0.5±0.6 vs CG: 0.1±0.5 p = 0.02). The interviews confirmed this result, emphasizing the key role of the trainer in improving their QoL. The adherence calculated as number of sessions performed compared to the sessions proposed was 75.8%. No injuries were observed. Conclusions The feasibility, the safety, and the positive effect of the proposed exercise protocol on QoL confirmed also by the interviews, show that principles of exercise education applied by trainers should be extended also to patients with other chronic condition. Key messages Trainers specifically educated, could be a means of achieving the goal improving people’s QoL, as they occupy the role of exercise experts and also an educational, relational and support role. The management of osteoporosis is multi-modal and includes exercise, often recommended as a beneficial non-pharmacological treatment to slow the rate of bone loss and improve quality of life.


2017 ◽  
Vol 87 (2) ◽  
pp. 184-200 ◽  
Author(s):  
Ana Belen Navarro-Prados ◽  
Sara Serrate-Gonzalez ◽  
Jose-Manuel Muñoz-Rodríguez ◽  
Unai Díaz-Orueta

Personality traits of older adults and their contribution to life satisfaction and generative interest were assessed. A total of 342 older participants (66% women), mean age = 67.89 years old ( SD = 6.52, range = 55–84 years old), who attended the University of the Experience in Salamanca (Spain), were evaluated. Information on sociodemographic data, perceived health and activity, personality traits, generativity, and life satisfaction was collected using self-reported questionnaires. Results confirmed a relation between personality traits, life satisfaction, and generativity. In addition, generative concern, neuroticism, extraversion, agreeableness, and conscientiousness predicted life satisfaction at this stage. Moreover, the role of personality on generativity was confirmed. Individuals with interest and agreeableness toward others, who are organized, persistent, and motivated, are more predisposed to generativity. These results open the way to develop intervention programs that enhance positive personality traits and generative interest to improve quality of life of older people.


2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 1335.1-1335
Author(s):  
M. Saifridova ◽  
M. Vranova ◽  
L. Linkova ◽  
S. Sebkova ◽  
J. Belacek ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
R. Masekela ◽  
R. J. Green

Non-cystic fibrosis-related bronchiectasis is a chronic inflammatory lung disease, which is regarded as an “orphan” lung disease, with little research devoted to the study of this condition. Bronchiectasis results in impaired quality of life and mortality if left untreated. The tools available in the armamentarium for the management of bronchiectasis entail antibiotic therapy traditionally used to treat exacerbations, stratagems to improve mucociliary clearance, and avoidance of toxins. Macrolides have been known for the last two decades to have not only anti-bacterial effects but immunomodulatory properties as well. In cystic fibrosis, the use of macrolides is well documented in subjects colonized withPseudomonas aeruginosa, to improve quality of life and lung function. There is currently emerging evidence to suggest the benefit of macrolides in subjects not colonized withPseudomonas aeruginosa. This beneficial effect has been less explored in the context of bronchiectasis from other causes. The purpose of this paper is to review the current literature on the use of macrolides in non-cystic fibrosis related bronchiectasis in paediatrics.


2018 ◽  
Vol 13 (1) ◽  
pp. 64 ◽  
Author(s):  
Athanasios Koutsoukis ◽  
Argyrios Ntalianis ◽  
Evangelos Repasos ◽  
Efsthathios Kastritis ◽  
Meletios-Athanasios Dimopoulos ◽  
...  

Cardio-oncology is a recently developed field in cardiology aimed at significantly reducing cardiovascular morbidity and mortality and improving quality of life in cancer survivors. Cancer survival rates have been constantly increasing, mainly because of the advent of new, more potent and targeted therapies. However, many of the new therapies – along with some of the older chemotherapeutic regimens such as anthracyclines – are potentially cardiotoxic, which is reflected increasingly frequently in the published literature. Cardiotoxicity adversely affects prognosis in cancer patients, thus its prevention and treatment are crucial to improve quality and standards of care. This review aims to explore the existing literature relating to chemotherapy- and radiotherapy-induced cardiotoxicity. An overview of the imaging modalities for the identification of cardiotoxicity and therapies for its prevention and management is also provided.


2021 ◽  
Author(s):  
Isabela Virgílio Cleto ◽  
Guilherme Silva Guimarães ◽  
Leticia Poloni dos Santos ◽  
Carolina Miguel Nôga ◽  
Leticia Moraes Aquino

Introduction: Ataxia is a symptom of several degenerative medical conditions; the most common in Brazil being Spinocerebelar ataxia (SCA). These patients have difficulty performing fine coordination motors activities, altered body balance and gait. The treatment is based on multidisciplinar rehabilitation, to improve quality of life and mantain general health. Health education (HE) can benefit these patients, but there are few reports about it, especially in SCA patients. Objectives: To search the literature for evidence of the use of HE in phyisiotherapy for SCA patients in Brazil. Design and settings: Study carried out at Centro Universitario São Camilo. Methodology: Literature review in the databases: Scielo, UNIFESP and LILACS, Key words: “SCA”, ”rehabilitation”, “HE” and “physiotherapy”, in Portuguese, English or Spanish . Results: 27 articles were found, of which 16 were eligible. Studies demonstrates the need for more evidence for HE to be part of the physiotherapist’s routine, encouraging the participation and autonomy of the patient and family in the rehabilitation process. It is possible to develop educational materials that complement the health guidelines for these patients. Conclusion: There is a literary gap about the direct role of the physiotherapist as a HE agent, with responsibilities beyond rehabilitation; within the scope of prevention, health promotion and self-management of the patient and family.


Author(s):  
John Weru

Palliative care is an interdisciplinary care to relieve suffering and improve quality of life for patients and their families. The development of effective combination antiretroviral therapy has transformed HIV from a terminal to a chronic condition, with patients living longer but also experiencing more extensive symptoms that significantly impact quality of life. As a result, the role of palliative care has evolved to ameliorating distressing symptoms including pain while at the same time offering psychosocial and spiritual support for patients and families and preparing them for a dignified death. This chapter discusses some of the challenges and symptoms that patients and families encounter as they face this life-limiting disease.


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