scholarly journals Clinical application of laryngeal electromyography – a point of view

2017 ◽  
Vol 7 (25) ◽  
pp. 39-46
Author(s):  
Georgiana Pasu

Abstract In recent years, the clinical importance of laryngeal electromyography (LEMG) has been recognized. This method of investigation proved itself to be a valuable and indispensable tool regarding voice disorder management and requires multidisciplinary approach. In this article, we focus on the clinical usefulness of LEMG to assess inferior and superior motor neuron integrity by recording action potentials generated by muscle fibers of the larynx in the new field known as neurolaryngology. To facilitate the clinical application of this electrophysiologic test, we present a detailed description of LEMG techniques, which were applied for simultaneous bilateral recordings of the thyroarytenoid, cricothyroid and posterior cricoarytenoid muscles. Also, we analysed and measured the following electrophysiological parameters: 1) insertional activity; 2) spontaneous activity; 3) recruitment; 4) morphology of waveform. From a practical point of view, in our country, LEMG performance is still not a routine procedure in ENT and Phoniatric Departments. The difficulty of practical use of LEMG in Romania consists in technical limitations and it depends on the physician’s experience regarding the examination technique and also the interpretation of electrophysiological results. Our current clinical experience shows that the use of LEMG contributes especially to the diagnosis, prognosis and treatment of patients with neurolaryngological disorders.

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Fernando Simón ◽  
Javier González-Miguel ◽  
Alicia Diosdado ◽  
Paula Josefina Gómez ◽  
Rodrigo Morchón ◽  
...  

Vector-borne transmitted helminthic zoonosis affects the health and economy of both developing and developed countries. The concept of episystem includes the set of biological, environmental, and epidemiological elements of these diseases in defined geographic and temporal scales. Dirofilariasis caused by different species of the genusDirofilariais a disease affecting domestic and wild canines and felines and man, transmitted by different species of culicid mosquitoes. This complexity is increased becauseDirofilariaspecies harbor intracellular symbiontWolbachiabacteriae, which play a key role in the embryogenesis and development of dirofilariae and in the inflammatory pathology of the disease. In addition, the vector transmission makes the dirofilariasis susceptible to the influence of the climate and its variations. The present review addresses the analysis of dirofilariasis from the point of view of the episystem, analyzing the complex network of interactions established between biological components, climate, and factors related to human activity, as well as the different problems they pose. The progress of knowledge on human and animal dirofilariasis is largely due to the multidisciplinary approach. Nevertheless, different aspects of the disease need to continue being investigated and cooperation between countries and specialists involved should be intensified.


2018 ◽  
Vol 8 (6-s) ◽  
pp. 279-286
Author(s):  
Sandeep Sharma ◽  
Ashish Baldi ◽  
Rajesh K. Singh ◽  
Rakesh Kumar Sharma

Recent era has witnessed an inordinate rise in the demand for radiopharmaceuticals due to their multifarious biomedical and clinical application. Scientific fraternity worldwide is continuously working in developing different innovative radiopharmaceuticals of immense clinical importance both from specialized theranostics and personalized medicine point of view. However, this increased production and use of radiopharmaceuticals in various nuclear medicine procedures have been accompanied by an inevitable problem concerning their storage after use and final disposal. Keeping in view the inherently hazardous nature of radiopharmaceuticals due to the presence of radionuclide in them, it is imperative to have an adequate regulatory backup which if followed meticulously can assure their safe storage and disposal so that threat to men and environment is prevented. The present work has been aimed to draft comprehensive regulatory guidelines for the storage and disposal of radiopharmaceuticals which is in resonance with the global standards. For this, the methodology consisting of a thorough research of existing guidelines from Atomic Energy Regulatory Board (AERB) exclusively on storage and disposal of radiopharmaceuticals in India has been done with the objective to identify and select various parameters not yet explicitly covered as is their scope. The guideline has been made to suitably address all sorts of necessary documentation, allocation of responsibility, ways of waste prevention, various mechanisms to deal with radiopharmaceuticals waste in all forms of matter and suggestive recommendations. Keywords: Radiopharmaceuticals, Atomic Energy Regulatory Board, Regulatory guidelines of radiopharmaceuticals


Author(s):  
Pragati B. Rakh ◽  
Madhavi D. Gaikwad ◽  
Deepa J. Amle

            Vyavachedak Nidan is distinguishing of particular disease or condition from others that present with similar clinical features. Dosha-Gati is basic consideration discussed by Charakacharya which keeps great clinical importance to the diagnostic (Roga Nidan) point of view; besides, prognosis (Sadhyasadhyata) and proper application of the treatment measures(Chikitsa karma) can be planned followed by assessment of Dosh- Gati through its classified aspects as the Tridosha  is the Samavayee karan of the Roga. Amlapitta is a very common disease in the present era. Amlapitta is one of the commonest vyadhi of Annavaha srotas, caused by vitiated agni. Amlapitta is a condition where amlaguna of pachak pitta (gastric juice) increases due to Samata. Amlapitta  has been considered as pittapradhana Kaphapradhana Tridoshaja Vyadhi. Acharya Madhava and Bhavamishra classified Amlapitta in two types according to doshagati or sthan dushti. The first type is Urdhvag amlapitta exhibits symptoms of pittaja and kaphaja Amlapitta and the second type is Adhog Amlapitta exhibits symptoms of vataja amlapitta. By understanding the various lakshanas of different type of Amlapitta in lite of doshagati can be beneficial for lakshana and samprapti vighatanatmak chikitsa.


Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2292
Author(s):  
Alessandro Bianchi ◽  
Isabella Taglieri ◽  
Verdiana Rimbotti Antinori ◽  
Fabrizio Palla ◽  
Monica Macaluso ◽  
...  

In Italy, Chianti Classico identifies a territory located in the heart of Tuscany that was once known as Chianti. From the pedological point of view, the entire DOCG (Denomination of controlled and guaranteed origin) has some common features but also shows many specific features related to certain small areas that give rise to the presence of many “terroirs”. Due to the intertwining created by the alternation of valleys and hills and the different characteristics of the territory, factors such as altitude and exposure play a very important role in the vegetative and productive expression of grapes. Some production areas were identified within the appellation where it is argued that the terroir and the grapes are quite distinct from those of other surrounding areas, albeit within the Chianti Classico appellation. On the basis of this information and considering that no data are available in the literature, the present study proposed an innovative multidisciplinary approach (analytical and statistical) that was capable of carrying out an objective evaluation of the various sub-areas investigated, using Sangiovese grapes as the variety in question. This research took into account the climatic results and the different pedological characteristics, evaluating the evolutionary phenomena that were linked to the ripening of the grapes in each phase of its formation.


1939 ◽  
Vol 32 (11) ◽  
pp. 1455-1467
Author(s):  
W. D. Newcomb

Attention is called to the difference between the pathologist's and the radiologist's point of view. The reasons for this difference are discussed with special emphasis on renal tumours. Classification of renal tumours. The first main groups are innocent and malignant. Are these really clear-cut or do they blend into one another? The commoner innocent renal tumours are adenoma, fibroma, myoma, lipoma, and angioma. These are rarely of any clinical importance but adenoma is a possible source of hypernephroma. Many elaborate classifications of cancer of the kidney have been proposed but the following four groups are sufficient for most puposes: Carcinoma, hypernephroma, sarcoma, and teratoid tumours. Much the commonest malignant renal tumour in adults is the hypernephroma, thought by Grawitz and others to be derived from ectopic adrenal rests. There is still no agreement concerning their origin but three views are held at the present time: ( a) All are carcinoma of renal tubules. ( b) Some are derived from renal tubules and some from ectopic adrenal. ( c) All are formed from adrenal tissue. These views are discussed with special reference to material in St. Mary's Hospital Museum, and it is suggested that the first view is the most probable although the second cannot be excluded. The teratoid tumours are the commonest in infants and swine. The differences between them and hypernephromata are described. The renal Pelvis, ureter, and bladder all have tumours of the same type and can conveniently be considered together. Connective tissue tumours, both innocent and malignant, are very rare. Papilloma and carcinoma are rare in the pelvis and ureter, but commoner in the bladder. The relation between these two tumours is discussed.


2020 ◽  
Vol 1 (1) ◽  
pp. 22-34
Author(s):  
Paolo Bellavista ◽  
Antonio Corradi ◽  
Luca Foschini ◽  
Eliza Helena Gomes ◽  
Elena Lamberti ◽  
...  

The wide availability of accurate sensors currently hosted by smartphones are enabling new participative urban management opportunities. Mobile crowdsensing (MCS) allows people to actively participate in any aspect of urban planning, by collecting and sharing data, reporting issues to public administrations, proposing solutions to urban planners, and delivering information of potential social interest to their community. Although collected data can be very helpful to enhance the quality of life of citizens, mobile users are still reluctant to use their devices to take advantages of the opportunities offered by the digitized society, mainly due to privacy issues. From August to December 2018, the city of Florianópolis, capital of Santa Catarina, in southern Brazil, was used as a living lab environment for an MCS application called ParticipACT Brazil, a socio/technical-aware crowdsensing platform. While the current literature focuses on MCS from a purely technical point of view, this research demonstrated that a multidisciplinary approach that includes both human sciences and ICT is needed in order to better identify critical issues, highlights the untapped potential of MCS paradigm, and suggests research methodologies that could provide benefits for all the actors involved (researchers, public administrators, and citizens).


2020 ◽  
Vol 11 ◽  
pp. 204062232090429 ◽  
Author(s):  
Pablo Coto ◽  
Sabino Riestra ◽  
Paloma Rozas ◽  
Ana Señaris ◽  
Rubén Queiro

Background: Our objective was to provide consensus recommendations on the optimal management of the immune-mediated inflammatory diseases (IMIDs) seen in patients with spondyloarthritis (SpA) using a multidisciplinary approach, and to develop a simple tool to help earlier recognition and referral of coexisting IMIDs in patients who already have one type of IMID. Methods: A total of 28 experts in the multidisciplinary management of the SpA-associated IMIDs assessed two questionnaires: one with statements focused on the multidisciplinary management of IMIDs, and a second questionnaire focused on questions useful for early recognition and referral. Panelists assessed the statements with a 9-point ordinal scale (1 = strongly disagree, 9 = strongly agree) using a modified Delphi methodology. Results: Consensus was reached on 72 out of the 82 statements (87.8%). Panelists agreed that the multidisciplinary approach to IMIDs is not sufficiently developed. The creation of multidisciplinary IMID units might be necessary. These units might focus primarily on patients with two or more coexisting IMIDs, or on IMIDs that are especially complex from a diagnostic or therapeutic point of view. Specialists who attend to patients with IMIDs should perform a screening for other coexisting IMIDs. A simple tool to help earlier recognition and referral of coexisting IMIDs is proposed. Conclusions: There is a need to improve care for patients with SpA-associated IMIDs. We provide expert recommendations to guide the adoption of a multidisciplinary approach for these cases, and a simple tool that may be useful for earlier recognition of coexisting IMIDs.


2010 ◽  
Vol 24 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Robert T. Sataloff ◽  
Phurich Praneetvatakul ◽  
Reinhardt J. Heuer ◽  
Mary J. Hawkshaw ◽  
Yolanda D. Heman-Ackah ◽  
...  

1989 ◽  
Vol 98 (2) ◽  
pp. 87-92 ◽  
Author(s):  
Roger L. Crumley

Basic research and surgical cases have shown that the injured recurrent laryngeal nerve (RLN) may regenerate axons to the larynx that inappropriately innervate both vocal cord adductors and abductors. Innervation of vocal cord adductor muscles by those axons that depolarize during inspiration is particularly devastating to laryngeal function, since it produces medial vocal cord movement during inspiration. Many patients thought to have clinical bilateral vocal cord paralysis can be found to have synkinesis on at least one side. This will make the glottic airway smaller, particularly during inspiration, than would true paralysis of all the intrinsic laryngeal muscles. Patients with bilateral vocal cord paralysis should undergo laryngeal electromyography. If inspiratory innervation of the adductor muscles is present, simple reinnervation of the posterior cricoarytenoid muscle will fail. The adductor muscles also must be denervated by transection of the adductor division of the regenerated RLN.


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