scholarly journals Glycoregulation During Pregnancy

2019 ◽  
Vol 20 (2) ◽  
pp. 9-16
Author(s):  
Violeta Mladenovic ◽  
Milica Dimitrijevic-Stojanovic ◽  
Djuro Macut ◽  
Aleksandar Djukic

Abstract Pregnancy is a period marked by profound changes in a woman’s hormonal status and metabolism, including the development of a carbohydrate-intolerant state. Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. The aim of this study was to estimate and analyse the parameters of glycaemic control during pregnancy. We stratified patients into the following three groups according to OGTT results: normal glucose tolerance (NTG), gestational impaired glucose tolerance (GIGT) and GDM. We investigated 92 pregnant women, diagnosed with vital and desired pregnancy up to 12 weeks of gestation, who had signed informed consent forms. Among them, 7 pregnant women had a spontaneous abortion, while 8 pregnant women dropped out, so a total of 77 pregnant women completed the trial. Most of the women examined had no risk factors (48%), while 35% of the women had one risk factor. The current study demonstrates that normal glucose tolerance was shown in 59 (76.6%) participants, while some form of glucose intolerance (GIGT or GDM) was shown in 18 (23.4%) patients. Our findings revealed an increase in glucose intolerance with advancing pregnancy (in the second and third trimester). In conclusion, we demonstrate that the difference in the quality of glycaemic control during pregnancy is manifested in the second and third trimester, until it manifests in the first trimester. These findings underpin the clinical significance of discovering GDM.

Author(s):  
Tahmineh Ezazi Bojnordi ◽  
Sedigheh Hantoushzadeh ◽  
Masomeh Sabzevary ◽  
Zahra Heidari

Background: Gestational diabetes mellitus (GDM) deserves proper prevention, diagnosis, and management due to healthcare implications from both maternal and fetal concerns. Objective: To evaluate the rate and investigate the risk factors for developing GDM. Materials and Methods: In this case-control, universal screening for GDM between 24 and 28 wk of gestation was performed in 613 pregnant women attending a prenatal clinic in Tehran who were followed-up until delivery between March 2017 to March 2018. Of the 613 women, 143 had GDM and 470 had normal glucose tolerance test as the primary diagnosis. Some GDM risk factors were compared in two groups. Results: Impaired glucose tolerance test was detected in 143 (23.3%) patients. Prevalence of GDM was higher in the first-trimester fasting blood sugar (FBS) > 90 qmg/dl group (p < 0.001). Comparison of the GDM and the normal glucose tolerance test groups demonstrated significant differences in maternal age, first-trimester FBS, third-trimester vitamin D level, maternal platelet count, maternal body mass index (BMI) (before 12 wk of gestation), weight gain during pregnancy, and the history of gestational complications in previous pregnancy (p < 0.01). In logistic regression, GDM was independently associated with older maternal age, higher first-trimester FBS, the history of gestational complications in previous pregnancy, lower third-trimester vitamin D level, and higher maternal platelet count (p < 0.01). Conclusion: Both patients with higher initial FBS and the history of gestational complications in previous pregnancy should be considered high risk for GDM and screened earlier. Key words: Diabetes Mellitus, Gestational, Blood glucose, Risk factor.


2018 ◽  
Vol 6 (2) ◽  
pp. 16
Author(s):  
Mezzi Wulandari Arenza ◽  
Ni Wayan Tianing ◽  
I Putu Adiartha Griadhi

ABSTRACTSleep disturbance in the third trimester pregnant women is caused by discomfort, an increasingly largeabdominal condition, back pain, frequent urination, fetal movement, heartburn, cramps in the legs, tiredness, difficultygetting started, and physiological changes. Sleep disorders result in decreased quality of sleep. Pregnant women whohave poor sleep quality are at risk of longer labor, cesarean delivery, premature birth, and even infant mortality. The aimof this research is to know the difference of pregnant exercise combination and back massage in improving the sleepquality of third trimester pregnant women. This research use experiment method with quasi experiment approach andresearch design is pre and post test with control design. Sample are 18 people, divided into 2 groups, 9 people intreatment groups given pregnancy exercise and back massage and 9 people in control group is given only pregnantexercise. Intervention is given 8 times. Pittsburgh Sleep Quality Index (PSQI) questionnaire used for measured of sleepquality. The result of different test of unpaired group, in the treatment group got difference of average 4,556 and controlgroup got difference mean 2,333 with p=0,004 (p<0,05). These results showed that there was a significant differencebetween the treatment group and the control group in improving the sleep quality of the third trimester pregnant women.In conclusion, there are differences in the addition of back massage combination in pregnancy exercise intervention inimproving sleep quality of third trimester pregnant women.Keyword : Pregnancy Exercise, Back Massage, Sleep Quality, Third Trimester.


Author(s):  
Eiichiro Satake ◽  
Rie Matsushita ◽  
Kazuteru Kitsuda ◽  
Kohnosuke Ohtaka ◽  
Eiko Nagata ◽  
...  

AbstractUrinaryIn Study 1 (328 schoolchildren), fasting and postprandial UMI were measured, with ΔUMI defined as the difference between fasting and postprandial UMI levels. In Study 2, oral glucose tolerance tests and UMI measurements were conducted in 18 children with suspected having diabetes.For Study 1, ΔUMI was observed [−0.65 (−3.9, 1.35) mg/g creatinine]. For Study 2, children with diabetes or impaired glucose tolerance had a significantly higher ΔUMI than children with normal glucose tolerance.These studies demonstrated the normal range of UMI in children and possibility of a novel biomarker for early detection of glucose intolerance in children.


2018 ◽  
Vol 15 (2) ◽  
pp. 209-219
Author(s):  
Zulhajrah Zulhajrah ◽  
A I Jaya ◽  
A Sahari

Anemia in pregnancy is a common problem because it reflects the value of socio-economic welfare of society and has had enormous influence on the quality of human resources. Settings menu maternal anemia is an effort to maintain the condition of pregnant women with anemia. This study aims to obtain optimal value nutritional needs of pregnant women anemia in Ampana Tete District of Tojo Una-Una Central Sulawesi province by using the branch and bound method. The parameters used in this study are the type of staple foods (𝑥1 ), the type of vegetable(𝑥2 ), types of fruit(𝑥3 ), types of side dishes(𝑥4 ), green beans(𝑥5 ), and milk(𝑥6 ), Results show 1st, 2 nd, and 3 rd of 36 combinations known to the most optimal combination for all trimester is a combination of 14. For the first trimester are as many as rice, 348 g spinach were 116 g,chicken eggs as 482 gmuch,and green beans 138 g, at a cost of 𝑅𝑝. 15680,00, 2nd trimester is as much as rice, 381 g spinach amount to 167 g, chicken 690 g eggs, and green beans as much as 154 g and of milk 3 g at a cost of 𝑅𝑝 20498,50, and the third trimester is rice, 345 g spinach, 127 g, chicken 914 g eggs, and green beans 176 g, at a cost of 𝑅𝑝. 24086.00 per day. The analysis has not been as expected because one of the drawbacks is the use of linear programming linearity as sumption that sometimes does not correspond to reality.


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1505-P
Author(s):  
MISAKI TAKAKADO ◽  
YASUNORI TAKATA ◽  
TOSHIMI HADATE ◽  
YUMI MATSUSHITA ◽  
RYOICHI KAWAMURA ◽  
...  

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