scholarly journals Bioactive Phenolics from Carthamus lanatus L.

2003 ◽  
Vol 58 (9-10) ◽  
pp. 704-707 ◽  
Author(s):  
Rilka Taskova ◽  
Maya Mitova ◽  
Bozhanka Mikhova ◽  
Helmut Duddeck

AbstractTwo flavonoid aglycons, eight flavonoid glycosides, chlorogenic acid and syringin were isolated from aerial parts of Carthamus lanatus. Isorhamnetin 3-O-β-ᴅ-glucoside and chlorogenic acid were found for the first time in the genus Carthamus and respectively, quercimeritrin, astragalin, kaempferol 3-O-β-ᴅ-sophoroside and syringin in the species. The ethyl acetate fraction of the methanol extract exhibited a higher antioxidant activity than the butanol fraction measured by the α,α-diphenyl-β-picrazylhydrazyl (DPPH) free radical scavenging assay. Cytotoxicity and antioxidant activities of the main constituent, luteolin 7-O-β-D-glucoside, were evaluated.

1970 ◽  
Vol 43 (4) ◽  
pp. 449-454 ◽  
Author(s):  
Sadia A Chowdhury ◽  
M Hossain Sohrab ◽  
Bidyut K Datta ◽  
Choudhury M Hasan

Lupeol (1) and Stigmasterol (2) were isolated from the crude extracts of the stem bark of Citrus macroptera (Family: Rutaceae) for the first time. The n-hexane, dichloromethane and methanol extracts were screened in vitro for antioxidant activity using the 1, 1-diphenyl-2-picrylhydrazyl-hydrate (DPPH) free radical scavenging assay. The hot methanol extract showed potential antioxidant activity (IC50: 178.96 μg/ml) whereas the cold methanol and dichloromethane extracts showed moderate activity (IC50: 242.78 μg/ml and 255.78 μg/ml respectively). Mild antioxidant activity was observed with the n-hexane extract of the stem bark of Citrus macroptera (IC50: 422.94 μg/ml). Key words: Citrus macroptera, Rutaceae, Lupeol, Stigmasterol, Antioxidant.   doi: 10.3329/bjsir.v43i4.2235 Bangladesh J. Sci. Ind. Res. 43(4), 449-454, 2008


Data in Brief ◽  
2018 ◽  
Vol 17 ◽  
pp. 870-875 ◽  
Author(s):  
Kotaro Hara ◽  
Takao Someya ◽  
Katsura Sano ◽  
Yoshimasa Sagane ◽  
Toshihiro Watanabe ◽  
...  

2015 ◽  
Vol 39 ◽  
pp. 49-55 ◽  
Author(s):  
H. Ouakouak ◽  
M. Chohra ◽  
M. Denane

Aerial parts of Mentha pulegium L. collected from south east of Algeria (Reguiba, El-Oued) possessed an essential oil in 2.34% (v/w) yield. GC and GC-MS analysis of the oil revealed recognition of Thirty-seven compounds, representing 95.02% (area percent) of the total oil composition. Oil was rich in Oxygenated hydrocarbons, exhibited higher percentage of Pulegone (46.31%) followed by Piperitenone (23.3%), Menthone (6.2%) and Limonene (4.7%). The antioxidant activity by DPPH free radical scavenging bioassay (IC50 = 157 µl/ml).


2017 ◽  
Vol 60 (2) ◽  
pp. 118-120
Author(s):  
Naseem Zahra ◽  
Muhammad Khalid Saeed ◽  
Ashi Nazir ◽  
Ijaz Ahmad ◽  
Alim-un- Nisa ◽  
...  

Present study was designed to evaluate the nutritional values of red skin potatoes collected fromGujranwala and Lahore regions of Pakistan. Potatoes (Solanum tuberosum) of Gujranwala and Lahorewere found to contain moisture contents of 5.00 and 5.15%, respectively. Fat was 0.19% in S. tuberosumof Gujranwala whereas Lahore potatoes were found to contain fat 0.2%. Fibre content of S. tuberosum ofGujranwala was 16.47% while S. tuberosum of Lahore had 13.45% fibre. Protein contents of S. tuberosumof Gujranwala were 12.89% whereas for S. tuberosum of Lahore were 13.11%. The water extract showedsignificant free radical scavenging activities in DPPH radical scavenging antioxidant assay and antioxidantactivity was increased in a dose dependent manner. These results suggest that potato (S. tuberosum) is notonly a cheap source of very important nutritents but also has antioxidant activities which are helpful tomaintain different physiological functions of body.


2020 ◽  
Vol 8 (1) ◽  
pp. 12-16
Author(s):  
Kengo Hori ◽  
Hari Prasad Devkota

Adenophora triphylla (Thunb.) A. DC. var. triphylla (Family: Campanulaceae) is distributed in Japan, Korea, and China. It is locally known as “Saiyousyajin” in Japan and the roots are used in traditional medicine to treat chronic bronchitis and whooping cough, and also as anti-inflammatory and anti-tussive agents. Till now, there is no report on the chemical constituents of aerial parts. Thus, the main aim of this study was to isolate and identify major chemical constituents of aerial parts of A. triphylla var. triphylla, and to evaluate their free radical scavenging activity. The 70% methanol extract of the aerial parts was subjected to repeated column chromatography using MCI gel CHP-20P, Sephadex LH-20, ODS and silica gel columns to isolate the five phenolic components (1-5). Free radical scavenging activity of the extract and compounds was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity method. The structures of the isolated compounds were elucidated as luteolin (1), luteolin 4’-O-b-glucopyranoside (2), luteolin 7-O-b-glucopyranoside (3), luteolin 7-O-neohesperidoside (4) and chlorogenic acid (5) based on their nuclear magnetic resonance (NMR) spectral data and comparison with literature values. All these compounds were isolated for the first time from A. triphylla var. triphylla. Extract showed weak free radical scavenging activity. Among isolated compounds, luteolin (1), luteolin 7-O-b-glucopyranoside (3), luteolin 7-O-neohesperidoside (4) and chlorogenic acid (5) showed potent free radical scavenging activity. Results from this study suggest that the aerial parts of A. triphylla var. triphylla might be a potential plant source for the development of functional foods, however further detailed research is necessary.


2008 ◽  
Vol 86 (9) ◽  
pp. 892-898 ◽  
Author(s):  
Wen-Hao Chen ◽  
Xing-Ming Ma ◽  
Quan-Xiang Wu ◽  
Yan-Ping Shi

Three new phytochemicals, a polyacetylene, 1,2-dihydrodendroarboreol B (1), an ionone derivative, (3S,5R,6S,7E)-3-tetradecanoate-5,6-epoxy-β-ionone (4), and a flavonol diglycoside, quercetagetin-3,6,4′-trimethoxy-7-O-neohesperidoside (38), along with 35 known compounds with diverse structures, were isolated from the EtOH extract of the aerial parts of Tridax procumbens. The structures of 1, 4, and 38 were determined on the basis of comprehensive methods including UV, IR, NMR, HR-ESI-MS, and CD, and by comparison of the spectroscopic data with those reported for structurally related compounds. Compounds 4, (3S,5R,6S,7E)-5,6-epoxy-3-hydroxy-7-megastigmene-9-one (5), and icariside B1 (12) were tested for their abilities to inhibit SGC-7901 and HL-60 cells. The antioxidant activities of quercetagetin-3,6,4′-trimethoxyl-7-O-β-D-glucopyranoside (36), quercetin-3-methoxyl-4′-O-β-D-glucoside (37), and 38 were evaluated by measuring their free-radical-scavenging effects, using the DPPH free-radical method.Key words: Tridax procumbens, polyacetylene, ionone, flavonol, cytotoxicity, antioxidant activities.


2017 ◽  
Vol 6 (3) ◽  
pp. 77-87 ◽  
Author(s):  
Latifa El Ouasif ◽  
Abdelhakim Bouyahya ◽  
Rachid Zniber ◽  
Mostafa El Ghoul ◽  
Redouane Achour ◽  
...  

In the present study, a series of novel 2-mercapto-benzimidazolium were synthesized from 2-mercapto-benzimidazole with hydrocarbon chains. All compounds obtained are reported for the first time, and the structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR and mass spectrometry. The newly synthesized compounds were subjected to in vitro biological evaluation. The antibacterial activity was evaluated will diffusion assay and density optic method. The antioxidant activity was carried out using DPPH free radical scavenging assay. The result indicated that some compounds show convincing antibacterial activities against two microorganisms: Escherichia coli and Staphylococcus aureus. While, these molecules have not shown interesting antioxidant effects.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 757-759
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Chlorogenic Acid (CA) is the formation of an ester established among caffeic and quinic acid. CA contains hydroxyl based groups over an aromatic moiety and exhibits very effective anticancer, antimutational and antioxidant activities. This survey was performed for assessing the awareness about antioxidant activities of CA amongst dental students. A cross-sectional survey was performed with a pretested questionnaire with ten questions disseminated among 100 dental students. The questionnaire assessed the awareness about CA therapy, their dietary sources, medicinal uses, antioxidant activity, anti ischaemic activity and free radical scavenging effect of chlorogenic acid. The responses were recorded and analyzed. 7% were aware of dietary sources,5% were aware of medical uses, 5% were aware of mechanisms of antioxidant activity, 4 % were aware of the anti ischaemic activity, and 5% were aware of the free radical scavenging effect of chlorogenic acid. Awareness about the usage of CA therapy is very less among dental students. Increased awareness programs and sensitization programs should be conducted to improve the awareness levels.


2012 ◽  
Vol 7 (6) ◽  
pp. 1934578X1200700
Author(s):  
Tan Hor Yue ◽  
Anthony Ho Siong Hock ◽  
Lim Chan Kiang ◽  
Lim Yang Mooi

Phytochemical studies of the leaves and rhizomes of Paraboea pa niculata (Gesneriaceae) are reported for the first time. Three phenylethanoid glycosides were isolated and characterized as 3,4-dihydroxyphenethyl-(3″- O-β-D-apiofuranosyl)- β-D-glucopyranoside, calceoralarioside E, and acteoside. These isolates exhibited weak cytotoxic activity against the K-562 cell line with a 50% of cell killing rate of 40.18 μM, 27.05 μM, and 27.24 μM, respectively. In the DPPH free radical scavenging assay, their IC50 values were determined as 75.89 μM, 25.00 μM, and 26.04 μM, respectively.


Sign in / Sign up

Export Citation Format

Share Document