scholarly journals Effect of intravenous vitamin C supplementation on the quality of sleep, itching and restless leg syndrome in patients undergoing hemodialysis; A double-blind randomized clinical trial

2018 ◽  
Vol 7 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Shahdak Dadashpour ◽  
Minoo Sadat Hajmiri ◽  
Daem Roshani
Keyword(s):  
Clinical Trial ◽  
Vitamin C ◽  
Sleep Quality ◽  
Intervention Group ◽  
Hemodialysis Patients ◽  
Restless Leg Syndrome ◽  
Quality Of Sleep ◽  
Double Blind ◽  
Intravenous Vitamin

Introduction: Poor sleep quality is common among hemodialysis patients and can potentially predict morbidity, mortality and quality of life in these patients. On the other hand, hemodialysis patients are encountered with vitamin C deficiency. Objectives: The purpose of this study was to determine the effect of intravenous vitamin C on sleep quality, itching and restless leg syndrome in hemodialysis patients. Patients and Methods: In this double-blind randomized clinical trial, 90 qualified hemodialysis patients were gone under investigation in Sanandaj in 2016. Patients randomly allocated in two equal intervention and control groups. The main measured outcome was the Pittsburg Sleep Quality Index (PSQI) which consists of seven components. At the end of each hemodialysis session, the intervention group received vitamin C vial (500 mg/5 cc) intravenously, three times a week for 8 weeks and the control group received normal saline as placebo in the same way. Data were collected at pretreatment and after 2 months of treatment. Additionally raises questions related to restless leg syndrome and was assessed by VAS scale for determining the incidence of pruritus. Data were analyzed by independent t test, paired t test, Wilcoxon and chi-square tests. Results: Around 52.2% of subjects were female and 47.8% were male and most of them were in the age group above 50 years old. Results showed a notable difference in the value of itching and restless leg syndrome between the two groups as these values decreased significantly in the intervention group (P=0.0001). There was also a great difference in the quality of sleep disorder in subjective sleep quality, sleep latency and daily function between the two groups and those disorders was significantly lower in the intervention group (P=0.0001). Conclusion: This study showed that intravenous vitamin C can effectively improve sleep quality, itching and restless legs syndrome in hemodialysis patients.

scholarly journals Effects of Melatonin on Salivary Levels of Cortisol and Sleep Quality of Hemodialysis Patients: A Randomized Clinical Trial

2021 ◽  
Author(s):  
Elham Hasannia ◽  
Firoozeh Derakhshanpour ◽  
Mohammad Ali Vakili
Keyword(s):  
Clinical Trial ◽  
Sleep Quality ◽  
Randomized Clinical Trial ◽  
Hemodialysis Patients ◽  
Rate Of Change ◽  
Cold Chain ◽  
Double Blind ◽  
Cost Effective Treatment ◽  
Before And After

Objective: The aim of this study was to investigate the effects of exogenous melatonin on the quality of sleep in patients undergoing dialysis and to investigate its mechanism for the regulation of total circadian rhythm and salivary levels of cortisol in hemodialysis patients admitted to Pange Azar hospital in Gorgan in winter of 2017. Method: This was a double-blind randomized clinical trial. Samples were transferred to the laboratory by maintaining the cold chain. Then, the patients were divided into two groups. In a double-blind trial, one group received three mg melatonin and another group received placebo for two weeks at 10 PM. At the end of two weeks, sampling was performed to investigate the salivary level of cortisol under the same conditions. The research instrument was Pittsburgh questionnaire. Data were analyzed before and after intervention using SPSS 16 software. Results: Salivary levels of cortisol decreased significantly after the intervention in the melatonin group (melatonin: 1.40 ± 1.82 and placebo: 4.94 ± 4.43; P = 0.008). Salivary levels of cortisol in the morning after intervention were also lower in the melatonin group, but were not statistically significant (melatonin 3.99 ± 3.45 and placebo: 5.35 ± 4.9; P = 0.93). Also, the difference in salivary levels of cortisol at night and before and after intervention significantly decreased in melatonin group. PSQI difference (interventional dimension) and PSQI (before intervention) were significantly decreased in melatonin group (P = 0.0001). The rate of change in the subscales of sleep latency, sleep efficiency, and sleep disorders in the melatonin group than in the placebo group was significantly higher. Conclusion: Melatonin can be used as a safe and cost-effective treatment to improve sleep quality and can also reduce salivary cortisol increased in hemodialysis patients at night.

Opipramol Improves Subjective Quality of Sleep the Night Prior to Surgery: Confirmatory Testing of a Double-Blind, Randomized Clinical Trial

2011 ◽  
Vol 64 (1) ◽  
pp. 24-31 ◽  
Author(s):  
Michael Hueppe ◽  
David Hartge ◽  
Klaus-Dieter Stoll ◽  
Andrea Ros ◽  
Peter Schmucker ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Subjective Quality ◽  
Quality Of Sleep ◽  
Double Blind ◽  
Confirmatory Testing

The effect of continuous care model-based intervention on the quality of sleep in menopausal women: A clinical trial study

2019 ◽  
Author(s):  
Farzaneh AKBARI ◽  
sousan Heydarpour ◽  
Nader Salari
Keyword(s):  
Clinical Trial ◽  
Intervention Group ◽  
Control Group ◽  
Quality Of Sleep ◽  
Care Model ◽  
Continuous Care ◽  
Menopausal Women ◽  
Significant Difference ◽  
The Difference

Abstract BACKGROUND Sleep disorder, brings in many physical, behavioral, and mental problems. Applying continuous care model leads to proper recognition of the patient’s problems and involves the patient in solving health problems. This study aimed to determine the effect of continuous care model on the quality of sleep in menopausal women. METHODS AND MATERIALS A random clinical trial study was carried out with participation of 110 menopausal women visiting Kermanshah-based clinics (the west of Iran) in 2017. The participants were randomly assigned to intervention (n=55) and control (n=55) groups. The control group received the routine cares and in addition to the routine cares the intervention group attended four weekly group consultation sessions (60-90min). The quality of sleep in the two groups was assessed using Pittsburg Sleep Quality Index before, immediately after, and one month after the intervention. Data analyses were done using independent t-test, ANOVA with frequent measures, Friedman’s test, Wilcoxon’s post hoc test, and X2 test in SPSS (24). RESULTS The mean scores of quality of sleep before and after the intervention were significantly different in the intervention group (p=0.001). There was no significant difference between the two groups in terms of quality of sleep before (p=0.140) and immediately after the intervention (p=0.168). However, one month after, the difference between the two groups was significant (P<0.001). CONCLUSION Implementation of the continuous care model led to an improvement of quality of sleep in the menopausal women.

scholarly journals Physical Activity and Quality of Sleep in Patients with End-Stage Renal Disease on Hemodialysis: A Preliminary Report

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Vasiliki Theodorou ◽  
Eleni Karetsi ◽  
Zoe Daniil ◽  
Konstantinos I. Gourgoulianis ◽  
Vasileios T. Stavrou
Keyword(s):  
Physical Activity ◽  
Sleep Quality ◽  
Pittsburgh Sleep Quality Index ◽  
Social Activity ◽  
Hemodialysis Patients ◽  
Quality Of Sleep ◽  
Daily Lives ◽  
Stage Renal Disease ◽  
End Stage

Chronic kidney disease significantly impairs patients’ daily lives and worsens their quality of life. The aim of this study was to investigate the physical activity and quality of sleep, during three days (previous day of dialysis, on the day of dialysis and after day of dialysis), in patients with end-stage renal on hemodialysis. 12 hemodialysis patients were included in our study, answered the Pittsburgh Sleep Quality Index (PSQI) questionnaire, and for each patient were used a smart bracelet for three days (day-pre- and posthemodialysis and day at hemodialysis) to record daily physical activity (steps, distance) and estimate the quality of sleep. Results showed differences between three days average of steps and distance and PSQI parameters “…engaging in social activity?” (steps, p=0.006, distance, p=0.006) and “…enthusiasm to get things done?” (steps, p=0.029, distance, p=0.030). Our study suggests interrelationship between sleep quality and physical activity.

scholarly journals The Effect of Positive Thinking Training on Different Dimensions of Quality of Life of Hemodialysis Patients: A Randomized Controlled Clinical Trial

2020 ◽  
Vol 12 (3) ◽  
Author(s):  
Mahmoudreza Peyravi ◽  
Mehdi Amirkhani ◽  
Faeze Abadi ◽  
Ali Abbasijahromi ◽  
Shima Sheidaie ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Emotional Health ◽  
Intervention Group ◽  
Hemodialysis Patients ◽  
Controlled Clinical Trial ◽  
Life Questionnaire ◽  
Positive Thinking ◽  
Different Dimensions

Background: Nowadays, the quality of life of hemodialysis patients has decreased, which doubled the need for educational interventions. Objectives: The current study investigated the effect of positive thinking training on different dimensions of quality of life of hemodialysis patients. Methods: This is a controlled clinical trial study conducted on 70 hemodialysis patients in Fasa, Fars province, in 2019. The patients were selected using the simple sampling method. Then, they were divided into two groups of intervention (n = 35) and control (n = 35). After obtaining informed consent, the researchers asked the participants to complete the SF-36 Quality of Life Questionnaire. The intervention group was trained positive thinking skills in 8 workshop sessions; each lasted for 90 minutes. Data were analyzed using SPSS version 20. To analyze the data, statistical tests such as chi-square, Kolmogorov-Smirnov, independent, and t-test were used. Results: The mean and standard deviation of the patients’ quality of life in the intervention group increased from 35.95 ± 10.07 to 55.98 ± 11.71 (P < 0.001). The changes in patients’ quality of life before and after the intervention were also assessed in 8 dimensions, which showed that the quality of life of the patients did not change significantly in terms of physical function (P = 0.42) and physical pain (P = 0.62), but for other dimensions, it was significantly increased (P < 0.001). Conclusions: Positive thinking training improved the quality of life of hemodialysis patients, particularly in the dimensions of the emotional role, emotional health, energy and vitality, social performance, and general health is recommended.

scholarly journals GERIATRIC GYMNASTIC TO QUALITY OF SLEEP IN PTSW SENJARAWI BANDUNG

2018 ◽  
Vol 2 (2) ◽  
pp. 223
Author(s):  
Meilirianta Meilirianta ◽  
Maspupah Maspupah
Keyword(s):  
Sleep Quality ◽  
Intervention Group ◽  
The Elderly ◽  
Control Group ◽  
P Value ◽  
Quality Of Sleep ◽  
Control Group Design ◽  
Equivalent Control ◽  
The Impact

Introduction. Elderly has decreased in many body system including the impact on sleep disorder. The purpose of this study was to analize effect of geriatric gymnastic on sleep quality of the elderly. Methods. This research used quasy experiment methods with pre and post test only non equivalent control group design. The population in this study was the elderly as many as 82 people. Sample in this research was 30 participants that are defi ned with total sampling method who was appropriated with the criteria. Sampel was devided into two groups which are 15 people of intervention group and 15 people of control group. Data instrument in measuring the quality of sleep used PSQI (Pittsburgh Sleep Quality Index) by observation. Result. There was a signifi cant effect of geriatric gymnasticon sleep quality of the elderly at Tresna Werdha Senjarawi Social Home Bandung with t-test, p-value 0.000 or < 0.05. Discussion. The geriatric gymnastics can be designed more interest the elderly to follow this activities regulary so can overcome sleep disorders in the elderly.Keywords : Quality of Sleep, Geriatric Gymnastic, Elderly

scholarly journals The Effects of Brain Gym on Quality of Sleep, Anxiety in Elderly at Nursing Home Care Case Medan

2019 ◽  
Vol 7 (16) ◽  
pp. 2595-2598
Author(s):  
Elmeida Efffendy ◽  
Novi Prasanty ◽  
Nurul Utami
Keyword(s):  
Nursing Home ◽  
Sleep Quality ◽  
Rating Scale ◽  
Intervention Group ◽  
Nursing Home Care ◽  
Cellular Damage ◽  
Quality Of Sleep ◽  
Brain Gym ◽  
Post Test

BACKGROUND: The ageing process of human will cause changes in anatomy and physiology. Biologically, ageing is associated with the gradual accumulation of various molecular and cellular damage. Disorders of sleep quality are influenced by several factors, such as the medical condition of illness, stress, anxiety, and others. Brain gym is a collection of simple movements that aim to connect or unite the mind and body. AIM: To find out the effect of brain gym in the quality of sleep and anxiety in the elderly at nursing home Karya Kasih Medan. SETTING AND DESIGN: This is an experimental pre and post-test design with non-probability consecutive sampling. METHODS: This study involved 68 elderly who undergone brain gym for eight weeks. These patients were recruited from the nursing home Karya Kasih Medan, Indonesia. This study was conducted in July-November 2018. This study was approved by the local ethical committee. The Pittsburgh Sleep Quality Index (PSQI) is used to assess sleep quality. Anxiety is assessed using the Hamilton Rating Scale for Anxiety (HARS). Data were analysed by paired t-test of SPSS version 22. RESULTS: PSQI score pre-test [mean (SD); 16.39 (0.68)] and post-test [mean (SD); 8.99 (0.89)], (p < 0.001). HARS score pre-test [mean (SD); 20.4 (6.7)] after post-test [mean (SD); 10.7 (5.2)], (p < 0.001). CONCLUSION: Brain gym increased the score level of the PSQI and HARS in the intervention group (p < 0.001).

scholarly journals EFEK PIJAT KAKI TERHADAP KUALITAS TIDUR IBU MENOPAUSE

2020 ◽  
Vol 6 (3) ◽  
pp. 293-297
Author(s):  
Rahmi Nurrasyidah
Keyword(s):  
Sleep Quality ◽  
Intervention Group ◽  
Pharmacological Therapy ◽  
Control Group ◽  
Quality Of Sleep ◽  
Average Quality ◽  
Post Test ◽  
Improve Sleep Quality ◽  
And Control

ABSTRACT  Background : Sleep disturbance is a problem that is often complained of by women who experience a menopause transition. This has an impact on quality of life, moods, productivity, and physical health. Foot massage therapy is a non-pharmacological therapy performed to improve sleep quality. Non-pharmacological therapy is an option because it is cheaper and more effective when compared with medical administration.  Purpose :This study determined an effect of foot massage on the sleep quality of menopausal mothers.  Method : This is an experimental study with a post test only control group design. The sample consisted of 23 respondents aged 45-55 years. The intervention group included 12 respondents and the control group included 11 respondents. The intervention group performed foot massage for 10 minutes on each leg. Sleep quality in the intervention group was measured 24 hours after massage. The control group did not do foot massage. Results :  the average respondent of intervention and control groups were in the best sleep quality (76100). In the control group, poor sleep quality was found in the wakefulness sleep category. There was no difference in the average quality of sleep in mothers who did foot massage and did not do foot massage (p> 0.001) with a difference in average (95% CI) 4.5 (3.6-12.5). Conclusion : There was no difference in the average quality of sleep between intervention and control group.  Sugestion : Based on the results of the study, the authors recommend the need for further research on foot massage with an increase in  duration of the intervention and it is necessary to investigate the variations of foot massage methods with aromatherapy to improve sleep quality. Further research needs to be done with more samples and better RCT methods.  Keywords: Foot massage, sleep quality, Menopause   ABSTRAK  Latar Belakang : Gangguan tidur adalah masalah yang sering dikeluhkan ibu yang mengalami transisi menopause. Hal ini berdampak pada kualitas hidup, suasana hati, produktivitas, dan kesehatan fisik. Terapi pijat kaki merupakan terapi non farmakologi yang dilakukan untuk meningkatkan kualitas tidur. Terapi non-farmakologi menjadi pilihan karena biaya yang lebih murah dan lebih efektif bila dibandingkan dengan pemberian medikamentosa. Tujuan : Untuk mengetahui pengaruh pijat kaki terhadap kualitas tidur ibu menopause.  Metode : Desain Penelitian ini adalah penelitian eksperimental dengan desain post test only control group desain. Sampel terdiri dari 23 responden yang berumur 45-55 tahun dengan rincian kelompok intervensi 12 responden dan kelompok kontrol 11 responden. Kelompok intervensi dilakukan pijat kaki selama 10 menit pada setiap kaki. Kualitas tidur pada kelompok intervensi diukur 24 jam setelah dilakukan pemijatan. Kelompok kontrol tidak dilakukan pijat kaki.  Hasil : Rata-rata responden pada kelompok intervensi maupun kontrol berada pada kualitas tidur terbaik (76-100). Pada kelompok kontrol, didapatkan kualitas tidur yang buruk pada kategori terbangun saat tidur (Awakenings). Tidak terdapat perbedaan rerata kualitas tidur pada ibu yang dilakukan pijat kaki dan tidak dilakukan pijat kaki (p>0,001) dengan perbedaan rerata (IK 95%) 4.5 (3.6-12.5).  Kesimpulan : Tidak terdapat perbedaan rerata kualitas tidur pada kelompok intervensi maupun kontrol. .  Saran  : Penulis merekomendasikan perlunya dilakukan penelitian lebih lanjut mengenai pijat kaki dengan peningkatan durasi intervensi serta perlu diteliti mengenai variasi metoda pijat kaki dengan aromaterapi untuk meningkatkan kualitas tidur. Penelitian selanjutnya perlu dilakukan dengan sampel yang lebih banyak dengan metode uji kilnis yang lebih baik.  Kata Kunci : Pijat kaki, kualitas tidur, Ibu Menopause

scholarly journals Does synbiotic supplementation affect the quality of life in children with cystic fibrosis? A pilot randomized controlled clinical trial

2020 ◽  
Author(s):  
Nemat Bilan ◽  
Effat Marefat ◽  
Leila Nikniaz ◽  
Mahdieh Abbasalizad Farhangi ◽  
Zeinab Nikniaz
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Cystic Fibrosis ◽  
Demographic Data ◽  
Intervention Group ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
The Mean ◽  
Synbiotic Supplementation

Abstract Background: There is no clinical trial that assesses the effect synbiotic supplementation on HRQOL in CF children. Considering the importance of HRQOL as an essential primary outcome and determinant of therapeutic benefit in chronic diseases like cystic fibrosis, the present clinical trial aimed to determine the efficacy of synbiotic supplementation on HRQOL in children with CF.Methods: In the present double-blind randomized clinical trial, 40 CF children were randomly allocated to the two groups. The intervention group was supplemented with synbiotics supplements and the patients in the placebo group received maltodextrin for six months. Demographic data and information about antibiotic use were recorded using the questionnaire. The health-related quality of life was assessed using the Persian version of quality of life inventory questionnaires. Paired t-test and ANCOVA were used for statistical analysis. Results: Totally, 36 participants completed the trial. The mean score of HRQOL was 76.34±17.33. There were no significant differences between synbiotic and placebo groups regarding baseline demographic and quality of life characteristics. Compared with baseline values, the mean total score and subscores of quality of life did not change significantly after synbiotic and placebo supplementation (p>0.05). Moreover, the results of ANCOVA showed that there were no significant differences between the two groups regarding the post-trial value of HRQOL total score and subscores. Conclusion: According to results, six-month supplementation with synbiotic did not have a significant effect on the HRQOL in children with CF. However, further studies with larger sample sizes and using more disease-specific questionnaires are needed for a more precise conclusion. The protocol of the study was registered at Iranian registry clinical trials (Registration code: IRCT2017011732004N1; Registration date: 2017-02-14).

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