Prevalence of cardiometabolic risk factors among Saudi Women with vitamin D deficiency

2017 ◽  
Author(s):  
Kadi Hanan Al ◽  
Eman Alissa
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Saudi Women

scholarly journals Vitamin D levels and cardiometabolic risk factors in Portuguese adolescents

2016 ◽  
Vol 220 ◽  
pp. 501-507 ◽  
Author(s):  
Maria Cabral ◽  
Joana Araújo ◽  
Joana Teixeira ◽  
Henrique Barros ◽  
Sandra Martins ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Vitamin D Levels ◽  
Portuguese Adolescents

Dietary vitamin D intake, cardiovascular disease and cardiometabolic risk factors: a sex‐based analysis from the ATTICA cohort study

2020 ◽  
Vol 33 (5) ◽  
pp. 708-717
Author(s):  
M. Kouvari ◽  
D. B. Panagiotakos ◽  
C. Chrysohoou ◽  
M. Yannakoulia ◽  
E. N. Georgousopoulou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Vitamin D ◽  
Cohort Study ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Dietary Vitamin ◽  
Vitamin D Intake ◽  
Dietary Vitamin D

scholarly journals Association of 25-hydroxyvitamin D with cardiometabolic risk factors and metabolic syndrome: a mendelian randomization study

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Chi Chen ◽  
Yi Chen ◽  
Pan Weng ◽  
Fangzhen Xia ◽  
Qin Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Cardiometabolic Risk ◽  
Mendelian Randomization ◽  
Cardiometabolic Risk Factors ◽  
Metabolic Traits ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Genetically Determined

Abstract Background Low circulating vitamin D levels have been associated with increased risk of metabolic syndrome (MS) and cardiometabolic risk factors in multiple epidemiology studies. However, whether this association is causal is still unclear. We aimed to test whether genetically lowered vitamin D levels were associated with MS and its metabolic traits, using mendelian randomization (MR) methodology. Methods Ten thousand six hundred fifty-five participants were enrolled from the SPECT-China study, which was performed in 23 sites in East China during 2014 to 2016. Using four single-nucleotide polymorphisms (SNPs) in the DHCR7, CYP2R1, GC and CYP24A1 genes with known effects on 25(OH) D concentrations, we created a genetic risk score (GRS) as instrumental variable (IV) to estimate the effect of genetically lowered 25(OH) D on MS and cardiometabolic risk factors. MS was defined according to the International Diabetes Federation criteria. Results Lower measured 25(OH)D levels were associated with MS (OR 0.921, 95% CI 0.888, 0.954) after multivariable adjustment. However, the MR-derived odds ratio of genetically determined 25(OH) D for risk of MS was 0.977 (95% CI 0.966, 1.030). The MR-derived estimates for raised fasting plasma glucose was 0.578 (95% CI 0.321, 0.980) per 10 nmol/L GRSsynthesis determined increase of 25(OH) D levels. Conclusions We found no evidence that genetically determined reduction in 25(OH)D conferred an increased risk of MS and its metabolic traits. However, we created our GRS only on the basis of common variants, which represent limited amount of variance in 25(OH)D. MR studies using rare variants, and large-scale well-designed RCTs about the effect of vitamin D supplementation on MS are warranted to further validate the findings.

scholarly journals Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults

2016 ◽  
Vol 115 (11) ◽  
pp. 1994-2002 ◽  
Author(s):  
Lucinda J. Black ◽  
Sally Burrows ◽  
Robyn M. Lucas ◽  
Carina E. Marshall ◽  
Rae-Chi Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Vitamin D ◽  
Cardiometabolic Risk ◽  
Hdl Cholesterol ◽  
Cardiometabolic Risk Factors ◽  
Inverse Association ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Over Time

AbstractEvidence associating serum 25-hydroxyvitamin D (25(OH)D) concentrations and cardiometabolic risk factors is inconsistent and studies have largely been conducted in adult populations. We examined the prospective associations between serum 25(OH)D concentrations and cardiometabolic risk factors from adolescence to young adulthood in the West Australian Pregnancy Cohort (Raine) Study. Serum 25(OH)D concentrations, BMI, homoeostasis model assessment for insulin resistance (HOMA-IR), TAG, HDL-cholesterol and systolic blood pressure (SBP) were measured at the 17-year (n 1015) and 20-year (n 1117) follow-ups. Hierarchical linear mixed models with maximum likelihood estimation were used to investigate associations between serum 25(OH)D concentrations and cardiometabolic risk factors, accounting for potential confounders. In males and females, respectively, mean serum 25(OH)D concentrations were 73·6 (sd 28·2) and 75·4 (sd 25·9) nmol/l at 17 years and 70·0 (sd 24·2) and 74·3 (sd 26·2) nmol/l at 20 years. Deseasonalised serum 25(OH)D3 concentrations were inversely associated with BMI (coefficient −0·01; 95 % CI −0·03, −0·003; P=0·014). No change over time was detected in the association for males; for females, the inverse association was stronger at 20 years compared with 17 years. Serum 25(OH)D concentrations were inversely associated with log-HOMA-IR (coefficient −0·002; 95 % CI −0·003, −0·001; P<0·001) and positively associated with log-TAG in females (coefficient 0·002; 95 % CI 0·0008, 0·004; P=0·003). These associations did not vary over time. There were no significant associations between serum 25(OH)D concentrations and HDL-cholesterol or SBP. Clinical trials in those with insufficient vitamin D status may be warranted to determine any beneficial effect of vitamin D supplementation on insulin resistance, while monitoring for any deleterious effect on TAG.

scholarly journals Healthy changes in some cardiometabolic risk factors accompany the higher summertime serum 25-hydroxyvitamin D concentrations in Iranian children: National Food and Nutrition Surveillance

2018 ◽  
Vol 21 (11) ◽  
pp. 2013-2021 ◽  
Author(s):  
Bahareh Nikooyeh ◽  
Zahra Abdollahi ◽  
Majid Hajifaraji ◽  
Hamid Alavi-Majd ◽  
Forouzan Salehi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Total Cholesterol ◽  
Cardiometabolic Risk ◽  
Linear Regression Analysis ◽  
Cardiometabolic Risk Factors ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

AbstractObjectiveTo investigate seasonal variations of vitamin D status at different latitudes and if these changes are accompanied by corresponding variations in certain health parameters in children living in a broad latitudinal range in Iran.DesignLongitudinal study.SubjectsIn total, 530 apparently healthy children aged 5–18 years were randomly selected from six regions of Iran with a latitudinal gradient from 29°N to 37·5°N. All anthropometric and biochemical assessments were performed twice during a year (summer, winter). High BMI (Z-score >1), low HDL cholesterol (<40 mg/dl, males; <50 mg/dl, females) and high TAG (>150 mg/dl) were considered cardiometabolic risk factors.ResultsSerum 25-hydroxyvitamin D (25(OH)D) showed between-season variation, with significantly higher concentrations (mean (sd)) in summer v. winter (43 (29) v. 27 (18) nmol/l; P<0·001). Change of circulating 25(OH)D between summer and winter was negatively correlated with change of BMI (r=−0·16; P<0·001), TAG (r=−0·09; P=0·04) and total cholesterol (r=−0·10; P=0·02) and directly correlated with change of height-for-age Z-score (r=0·09; P=0·04). Multiple stepwise linear regression analysis (β; 95 % CI) showed that winter serum 25(OH)D (−0·3; −0·4, −0·2; P<0·001), gender (boys v. girls: 9·7; 5·2, 14·1; P<0·001) and latitude (>33°N v. <33°N: 4·5; 0·09, 9·0; P=0·04) were predictors of change of serum 25(OH)D between two seasons.ConclusionsSummertime improvement of vitamin D status was accompanied by certain improved cardiometabolic risk factors, notably serum TAG, total cholesterol and BMI, in children.

scholarly journals Effect of latitude on seasonal variations of vitamin D and some cardiometabolic risk factors: national food and nutrition surveillance

2020 ◽  
Author(s):  
Bahareh Nikooyeh ◽  
Zahra Abdollahi ◽  
Nastaran Shariatzadeh ◽  
Ali Kalayi ◽  
Maliheh Zahedirad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Seasonal Variations ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Food And Nutrition
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