Introduction. Theorization and modeling of pedagogical conditions in the professional activity of a scientific and pedagogical worker reveal the possibilities and prospects of including a person in the process of scientific knowledge, scientific research, research activities in the system of lifelong education and pedagogical science in general. The problem of using scientific theorization and pedagogical modeling in solving problems of determination and clarification of pedagogical conditions in the professional activity of a scientific and pedagogical worker is integrated, its solution is important from the standpoint of integrity and uniqueness, the relevance and prospects of the new scientific knowledge obtained in pedagogy as a science.Materials and Methods. In the structure of the determined scientific search, theoretical and empirical research methods were involved: analysis, synthesis, generalization, comparison, juxtaposition, scientific theorization, study of the work of teachers and student teachers, trainers and leaders, the registration method, the scaling method, methods of mathematical statistics. The foundations of scientific theorization were implemented in the context of the ideas of traditional pedagogical methodology (broad, narrow, local meanings), as well as innovative pedagogical methodology (adaptive-productive meaning, functional-labor meaning, epistemological-synergetic meaning).Results. Theorization and modeling of pedagogical conditions in the professional activity of a scientific and pedagogical worker is revealed through the possibilities of classical (traditional) and innovative pedagogy. The prospects for generalization and unification of the use of pedagogical conditions in the professional activity of a scientific and pedagogical worker are determined by the conditions for the development and correctness of the use of the foundations of scientific knowledge, scientific research and scientific and pedagogical research. Theorization and modeling of pedagogical conditions in the professional activity of a scientific and pedagogical worker makes it possible to improve the quality of solving problems of scientific research and professional pedagogical activity. Pedagogical conditions are a model for optimizing the quality of presentation and solving problems and problems of scientific research and scientific and pedagogical activity. Pedagogical conditions are determined by a system of provisions (models) and are used in scientific theorization and proving of various opportunities for improving the quality of professional and pedagogical activity. The system of lifelong education reveals the direction of the processes of theorizing and modeling of pedagogical conditions in the professional activity of a scientific and pedagogical worker.Discussion and Conclusions. Theorization and modeling of pedagogical conditions in the professional activity of a scientific and pedagogical worker reveals the prospects of ideas for creating a new didactic and professional pedagogical knowledge in the context of flexible management of the possibilities of using pedagogical modeling and scientific theorization. The quality of the use of scientific theorization and pedagogical modeling in the determination and clarification of pedagogical conditions in the professional activity of a scientific and pedagogical worker is determined in the ideas and constructs of classical and innovative pedagogy.