Letter To The Editor

PEDIATRICS ◽  
1970 ◽  
Vol 45 (1) ◽  
pp. 156-157
Author(s):  
Hans Ekelund ◽  
Ulla Hedner ◽  
Inga Marie Nilsson
Keyword(s):  
Clinical Significance ◽  
Umbilical Vein ◽  
Full Term ◽  
Fibrinolytic System ◽  
Pathological Conditions ◽  
Letter To The Editor ◽  
Term Newborns

The May 1969 issue (Pediatrics, 43: 770) contained an article by Stiehm and Clatanoff on "split products of fibrin in the serum of newborns." The authors discuss the origin of these split products and their possible clinical significance in different pathological conditions in the newborn. At our laboratory we have recently completed a study of the fibrinolytic system in newborns which will be published in Acta paediatrica Scandinavia (accepted for publication July 16, 1969). Our material consists of 207 normal, full term newborns, where blood has been collected by catheterization of the umbilical vein during the first 5 days of life.

LEVELS AND DISTRIBUTION OF FREE AND C4b-BP-B0UND-PR0TEIN S IN HUMAN FETUSES AND FULL-TERM NEWBORNS

1987 ◽  
Author(s):  
P MOALIC ◽  
Y GRUEL ◽  
P FOLOPPE ◽  
B DELAHOUSSE ◽  
G BODY ◽  
...  
Keyword(s):  
Umbilical Vein ◽  
Protein S ◽  
Full Term ◽  
Free Form ◽  
Reference Curve ◽  
Direct Puncture ◽  
A Value ◽  
Term Newborns ◽  
Low Levels ◽  
Normal Adults

Levels and plasmatic distribution of protein S were studied on umbilical cordplasmas from 25 normal full-term newborns (N) and 15 normal fetuses (F) between20 and 30 weeks of gestation. Samples from fetuses were collected for antenatal diagnosis by direct puncture of the umbilical vein under high resolution real-time ultrasound. Total protein S(PS) level was determined using Laurell rocket immuno-electrophoresis (Diagnostica Stago, Asnifcres-France). Free PS wasmeasured using this latter method, afterprecipitation of C4b-BP-bound-PS by polyethylene glycol (PEG). Normal pool plasma, treated as well, was considered as the reference curve. C4b-binding protein (C4b-BP) determinations were conducted by Laurell rocket immunoelectrophoresis. The qualitative distribution of free PS and C4b-BP-bound-PS in plasma was also assessed by crossed-immunoelectrophoresis(CIE). Results (mean - SD) were expressed in percentage, in relation to healthy adults values (n = 15). Low levels of total PS were obtained in all fetuses (16.4 ±4.2) and newborns (36.4 ±9.5) as compared to adults (91.6 ± 12.2). Free protein S level was also decreased both in fetuses (22.2 ±6.0) and newborns (48.5 ± 12.1 versus 89.4 ± 26.3 in adults). At these stages of development, the ratio Free PS / Total PS (both values were obtained according to a reference curve performed with a normal adult pool plasma untreated by PEG) was significantly higher as compared to normal adults (0.82 ±0.07 in F, 0.64 ±0.17 in N and 0.39 ±0.11 in A, p‹0.001, Student t test). The predominance of free PS was also visualized in the CIE patterns. These data may be explained by undetectable C4b-BP in 21-week old fetuses (‹2% in 10 cases). After the 26th week of gestation C4b-BP level was 7.8 ±7.4 ‹n=5) and reached a value of 19.2 ±15.6 in newborns (adults = 95.7 ±14.7). In human fetus and newborn, PS essentially circulates under free form and this might compensate the decrease of the total PS level.

Letter to the Editor

PEDIATRICS ◽  
1982 ◽  
Vol 70 (3) ◽  
pp. 505-505
Author(s):  
S. Voora ◽  
S. Srinivasan ◽  
L. D. Lilien ◽  
T. F. Yeh ◽  
R. S. Pildes
Keyword(s):  
Predictive Value ◽  
Full Term ◽  
Bacterial Disease ◽  
Not Given ◽  
Letter To The Editor ◽  
Term Newborns ◽  
Work Up

Huston's concern about the validity and predictive value of fever in detecting bacterial disease in full-term newborns is based on his questioning our methods of proving which of the nonfebrile infants had bacterial disease. Our method was not given in detail in the materials and methods of our paper. As is obvious, it is impossible, as well as unethical, to subject all newborns to septic work-up. During the study, as was routine in our nursery, we did, however, work-up all afebrile infants with symptoms possibly related to sepsis (contrary to what Huston said with respect to irritability and diarrhea).

The effect of early-onset infections on serum apelin-12 concentration in full-term newborns

2018 ◽  
Vol 2018 (2) ◽  
pp. 81-85
Author(s):  
Urszula Godula-Stuglik ◽  
Małgorzata Koba ◽  
Aneta Stachurska ◽  
Alicja Nawrat ◽  
Katarzyna Staśkiewicz ◽  
...  
Keyword(s):  
Early Onset ◽  
Full Term ◽  
Term Newborns

Weight/length ratio: is it a good index to assess the nutritional status of full-term newborns?

2002 ◽  
Vol 78 (3) ◽  
pp. 219-24 ◽  
Author(s):  
Taciana D. de A. Braga ◽  
Marília C. Lima
Keyword(s):  
Nutritional Status ◽  
Full Term ◽  
Length Ratio ◽  
Good Index ◽  
Term Newborns

scholarly journals Levels of Predominant Intestinal Microorganisms in 1 Month-Old Full-Term Babies and Weight Gain During the First Year of Life

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2412
Author(s):  
Sonia González ◽  
Marta Selma-Royo ◽  
Silvia Arboleya ◽  
Cecilia Martínez-Costa ◽  
Gonzalo Solís ◽  
...  
Keyword(s):  
Weight Gain ◽  
Gut Microbiota ◽  
Early Life ◽  
Later Life ◽  
Full Term ◽  
First Year ◽  
Term Infants ◽  
Term Newborns ◽  
Infant Weight Gain ◽  
First Year Of Life

The early life gut microbiota has been reported to be involved in neonatal weight gain and later infant growth. Therefore, this early microbiota may constitute a target for the promotion of healthy neonatal growth and development with potential consequences for later life. Unfortunately, we are still far from understanding the association between neonatal microbiota and weight gain and growth. In this context, we evaluated the relationship between early microbiota and weight in a cohort of full-term infants. The absolute levels of specific fecal microorganisms were determined in 88 vaginally delivered and 36 C-section-delivered full-term newborns at 1 month of age and their growth up to 12 months of age. We observed statistically significant associations between the levels of some early life gut microbes and infant weight gain during the first year of life. Classifying the infants into tertiles according to their Staphylococcus levels at 1 month of age allowed us to observe a significantly lower weight at 12 months of life in the C-section-delivered infants from the highest tertile. Univariate and multivariate models pointed out associations between the levels of some fecal microorganisms at 1 month of age and weight gain at 6 and 12 months. Interestingly, these associations were different in vaginally and C-section-delivered babies. A significant direct association between Staphylococcus and weight gain at 1 month of life was observed in vaginally delivered babies, whereas in C-section-delivered infants, lower Bacteroides levels at 1 month were associated with higher later weight gain (at 6 and 12 months). Our results indicate an association between the gut microbiota and weight gain in early life and highlight potential microbial predictors for later weight gain.

Interhemispheric amplitude symmetry in the EEGs of full-term newborns

1977 ◽  
Vol 43 (6) ◽  
pp. 846-852 ◽  
Author(s):  
Jerald L Varner ◽  
Robert J Ellingson ◽  
Theresa Dahahy ◽  
Bessmarie Nelson
Keyword(s):  
Full Term ◽  
Term Newborns

scholarly journals Randomized clinical trial of the effect of the onset time of skin-to-skin contact at birth, immediate compared to early, on the duration of breastfeeding in full term newborns

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Sergio I Agudelo ◽  
Oscar A Gamboa ◽  
Eduardo Acuña ◽  
Lina Aguirre ◽  
Sarah Bastidas ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Exclusive Breastfeeding ◽  
Negative Impact ◽  
Onset Time ◽  
Full Term ◽  
Breastfeeding Duration ◽  
Bivariate Analysis ◽  
Skin Contact ◽  
Term Newborns ◽  
Skin To Skin

Abstract Background Skin-to-skin contact (SSC) compared to separation at birth has a positive effect on breastfeeding. However, separation at birth is common with negative impact on breastfeeding. The aim was to determine the effect of immediate SSC compared to early SSC on the duration of exclusive breastfeeding. Methods A randomized multicentre parallel clinical trial was conducted in two hospitals in Cundinamarca (Colombia) between November 2018 and January 2020. Low-risk full term newborns at birth were included. Neonates were assigned to immediate (in the first minute after birth) or early onset (start exactly at 60 min of life) skin to skin contact. Monthly follow-up was performed until 6 months of age. The primary outcome was the percentage of exclusively breastfed infants at 6 months (time in months with human milk as the only source of food). Secondary outcomes were the percentage of infants with exclusive breastfeeding at 3 months, duration in months of exclusive breastfeeding, neonate’s breastfeeding ability, percentage of weight change between birth and the first week of life and hospitalization in the neonatal unit in the first week. A bivariate analysis was performed to determine the variables associated with exclusive breastfeeding at 6 months. A survival analysis was performed to evaluate the effect of the onset of SSC on exclusive breastfeeding duration. Results A total of 297 newborns were included: 49.8% (n = 148) in the immediate SSC group, and 50.2% (n = 149) in the early SSC group. The mean duration of exclusive breastfeeding in both groups was 5 months. There were no differences between the groups in the percentage of exclusive breastfeeding at 6 months (relative risk [RR] 1.06, 95% CI 0.72, 1.58) or in the duration of exclusive breastfeeding (hazard ratio [HR] 0.98, 95% CI 0.74, 1.28). Conclusions The percentage of infants and the duration of exclusive breastfeeding in the first 6 months of age were the same between the two groups of SSC interventions. Given the current barriers to its implementation, the results of this study could positively impact the use of SSC at birth and standardize the intervention and improve breastfeeding indicators. Trial registration ClinicalTrials.gov NCT02687685.

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