Handbook of Cardiology, by L. Jerome Krovetz, M.D., Ph.D., and Gerold L. Schiebler, M.D., with a foreword by Richard T. Smith, M.D. New York/Evanston, London: Hoeber Medical Division, Harper and Row, 1969, 388 pp., $16.50

PEDIATRICS ◽  
1970 ◽  
Vol 45 (2) ◽  
pp. 358-358
Author(s):  
Gladys J. Fashena
Keyword(s):  
New York ◽  
Physical Examination ◽  
Pediatric Cardiology ◽  
Common Disease ◽  
Experimental Production ◽  
Laboratory Examination ◽  
Cardiac Anomalies ◽  
Medical Division ◽  
Disease Entities

This concise, highly readable compendium grew out of an optimistic attempt by the authors, some years ago, to cover the field of pediatric cardiology in a 2-day lecture seminar! The general aim is to offer a brief basic introduction to pediatric cardiology, with emphasis on fundamental general considerations as well as the more common disease entities. The first 11 chapters deal with the basic tools of pediatric cardiology such as anatomy and embryology, experimental production and genetics of cardiac anomalies, abnormal hemodynamics, the physical examination, and the various modalities of laboratory examination.

Experimental Production of the Bi-Digital O-Ring Test Muscular Power Evaluation Device Using an Air-type Automatic Analysis System

2020 ◽  
Vol 45 (1) ◽  
pp. 15-30
Author(s):  
Yasuhiro Shimotsuura ◽  
Hiroyuki Maezawa ◽  
Yoshiaki Omura
Keyword(s):  
New York ◽  
Muscle Strength ◽  
Objective Evaluation ◽  
The Body ◽  
Ring Test ◽  
Experimental Production ◽  
Muscular Power ◽  
Strong Response ◽  
Staff Members ◽  
Diagnosis Method

As Bi-Digital O-Ring Test (originated and founded by Prof. Y. Omura in New York, 1997-2020; follow as BDORT)is a diagnosis method that is carried out on the basic theory of the physiological phenomenon called the decline of muscular power of fingers, the examiner, and patients (or mediator) are demanded to do BDORT by constant regular power. Namely BDORT is a diagnosis method that estimates the relative muscular decline of the patients, so there is such a view that the results of BDORT are reflected by consciousness of the examiner. The authors used the ORT tester by using air system to avoid the influence of electromagnetic wave and evaluated the decline of the muscle strength and open degree of the O-ring shaped by the patients. Patients of the Shimotsuura Clinic are subjected and checked by direct BDORT method. When the patients shapes the O-Ring, staff members stimulated the parts of the body by plastic stick and push foot switch. Decline of the muscle strength & open degree was evaluated. When the open degree was more than 20%, stimulated points were evaluated as abnormal. Opposite side arm of the O-Ring shaped arm was checked as control. The results of the direct BDORT method between ORT evaluation apparatus and the patient was consistent with the results of the indirect method of BDORT method between the doctor and the assistant. Even where the patients complain of ill, the muscle strength was declined and opened the O-Ring by using ORT evaluation apparatus. Especially in the parts of the strong response of Integrin α5β1 checked by the doctor, the muscle strength decreased and the open degree was much higher than other parts of the body. Patients could experience of BDORT by numeral objective evaluation of the decline of the muscle strength by using ORT evaluation apparatus.

scholarly journals Fixed-Dose Combination of NSAIDs and Spasmolytic Agents in the Treatment of Different Types of Pain—A Practical Review

2021 ◽  
Vol 10 (14) ◽  
pp. 3118
Author(s):  
Magdalena Janczura ◽  
Małgorzata Kobus-Moryson ◽  
Szymon Sip ◽  
Marcin Żarowski ◽  
Agnieszka Wareńczak ◽  
...  
Keyword(s):  
De Novo ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Common Disease ◽  
Therapeutic Principles ◽  
Spasmolytic Agents ◽  
Dose Combination ◽  
Disease Entities ◽  
Active Substances ◽  
Significant Therapeutic Effect

This review presents the most common disease entities in which combinations of NSAIDs and spasmolytic drugs are used to reduce pain. The benefits of fixed-dose combination products (FDCs) are that they improve the response in people with insufficient monotherapy. Using the synergy or additive effect of drugs, it is possible to obtain a significant therapeutic effect and faster action with the use of smaller doses of individual drugs. In addition, one active ingredient may counteract adverse reactions from the other. Another essential aspect of the use of FDCs is the improvement of medical adherence due to the reduction in the pill burden on patients. It is also possible to develop a fixed-dosed combination product de novo to address a new therapeutic claim and be protected by patents so that the manufacturer can obtain exclusive rights to sell a particular FDC or a formulation thereof. The proposed fixed-dose combinations should always be based on valid therapeutic principles and consider the combined safety profile of all active substances included in the medicinal product. This review aims to identify which combinations of NSAIDs and spasmolytics have been developed and tested and which combinations are still under development.

scholarly journals Rickets in Children: An Update

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 738
Author(s):  
Cristina Gentile ◽  
Francesco Chiarelli
Keyword(s):  
Vitamin D ◽  
Physical Examination ◽  
Vitamin D Deficiency ◽  
Preventive Measures ◽  
Rapid Diagnosis ◽  
Common Disease ◽  
Biochemical Tests ◽  
Nutritional Rickets ◽  
Laboratory Features ◽  
Radiologic Features

Rickets refers to a deficient mineralization of the growth plate cartilage, predominantly affecting longer bones. Despite the fact that preventive measures are available, it is still a common disease worldwide; nutritional rickets, due to vitamin D deficiency or dietary calcium inadequate intake, remains the most common form. Medical history, physical examination, radiologic features and biochemical tests are essential for diagnosis. Although recent studies suggest hypophosphatemia as the leading alteration, rickets is classically divided into two categories: calcipenic rickets and phosphopenic rickets. Knowledge of this categorization and of respective clinical and laboratory features is essential for rapid diagnosis and correct management. The aim of this review is to analyze the epidemiological, pathogenetic, clinical, and therapeutic aspects of the different forms of rickets, describing the novelties on this “long-lived” disease.

Review of Modern Management of the Rh Problem, by John T. Queenan, M.D. New York: Harper and Row (Hoeber Medical Division), 1967, 318 pp., $12.50

PEDIATRICS ◽  
1968 ◽  
Vol 42 (2) ◽  
pp. 379-379
Author(s):  
Thomas E. Cone
Keyword(s):  
New York ◽  
Amniotic Fluid ◽  
Fetal Death ◽  
Modern Management ◽  
Medical Division

Pity the busy practicing obstetrician who tries to keep up with the latest on the management of the "Rh problem" in his practice. Whereas once, there were only two Rh types, Rh positive and Rh negative, now there are more than two dozen, of which at least six can cause problems, though most rather rarely. And, there is a 20% danger of fetal death which may now be foretold by pigment changes in the amniotic fluid. So amniocentesis is an important prognostic measure.

The Surgery of The Common Congenital Cardiac Malformations, by Christiaan N. Barnard, M.D., M.Med. (Cape Town), M.S., Ph.D. (Minnesota), F.A.C.S., F.A.C.C., and Velva Schrire, M.Sc., Ph.D., M.D. (Cape Town), F.R.C.P.E., F.R.C.P., F.A.C.C. New York: Hoeber Medical Division, Harper and Row, Publisher (49 E. 33rd Street, New York, New York 10016), 1969, 179 pp., no price given

PEDIATRICS ◽  
1970 ◽  
Vol 45 (5) ◽  
pp. 898-898
Author(s):  
William F. Bernhard
Keyword(s):  
New York ◽  
Ductus Arteriosus ◽  
Cape Town ◽  
Postoperative Management ◽  
Septal Defects ◽  
Medical Division ◽  
New Information ◽  
Hemodynamic Characteristics ◽  
The Common ◽  
33Rd Street

This short (179 pages), well-composed text includes a presentation of the anatomy, hemodynamic characteristics, and surgical management of five congenital cardiovascular abnormalities. Although not much in the way of new information is offered, the material is easy to read and is followed by an excellent bibliography. Chapters dealing with patent ductus arteriosus, coarctation, atrial and ventricular septal defects, and tetralogy of Fallot comprise the materials covered by the text. With certain exceptions, for instance, the routine use of chloramphenicol as a postoperative antibiotic, the discussion of the surgical treatment and postoperative management of these anomalies is very well done.

scholarly journals Management of testicular torsion <360° in children: a single-center, retrospective study

2019 ◽  
Vol 48 (4) ◽  
pp. 030006051989586
Author(s):  
Xiang Guo ◽  
Lan Sun ◽  
Wei Lei ◽  
Shuang Li ◽  
Hui Guo
Keyword(s):  
Blood Flow ◽  
Retrospective Study ◽  
Survival Rate ◽  
Physical Examination ◽  
Testicular Torsion ◽  
Age Of Onset ◽  
Clinical Manifestations ◽  
Single Center ◽  
Laboratory Examination ◽  
Duration Of Symptoms

Objective This study aimed to summarize clinical manifestations, and physical examination, laboratory examination, and ultrasound results of children with testicular torsion <360°. Methods We performed a retrospective study of children who were diagnosed with testicular torsion <360° between October 2007 and October 2017. Results There were 11 (19.2%) patients with testicular torsion of 90°, 33 (58.0%) with 180°, and 13 (22.8%) with 270°. The median age of onset was 5.7 years (range, 1–14 years) and the median duration of symptoms was 4.2 days (range, 0.5–5 days). Ultrasound showed low blood flow in 46 (80.8%) patients. The testis was retained in 41 (72.0%) patients and resected in 16 (28.0%). The testes appeared necrotic at 2 to 3 days after onset for patients with 270° torsion, appeared necrotic at 3 to 4 days after onset for those with 180° torsion, and were not necrotic at 4 to 5 days after onset for those with 90° torsion. The duration of symptoms in children decreased as the torsion angle increased. Conclusion Children with testicular torsion <360° are relatively young, while the duration of symptoms is relatively long. A high postoperative testicular survival rate is one of the clinical features in this study.

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