Thrombocytopenic Purpura Associated With Exanthema Subitum

Postinfectious thrombocytopenic purpura in children is well known, and several viral infections have been incriminated, including rubella, measles, measles vaccination, chickenpox, mumps, smallpox vaccination, infectious mononucleosis, hepatitis, cytomegalovirus infection, and upper respiratory tract infection, as reviewed by McClure in the January 1975 issue of Pediatrics (page 68). It seems that thrombocytopenic purpura following exanthema subitum is not known in the English literature. We would like to present a brief summary of five such cases we have reported previously.1

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Severe Immune Thrombocytopenia Complicated by Intracerebral Haemorrhage Associated with Coronavirus Infection: A Case Report and Literature Review

European Journal of Case Reports in Internal Medicine ◽

10.12890/2019_001155 ◽

2019 ◽

Author(s):

Mohamed Magdi ◽

Ali Rahil

Keyword(s):

Case Report ◽

Tract Infection ◽

Intracranial Haemorrhage ◽

Immune Thrombocytopenia ◽

Autoimmune Disorder ◽

Upper Respiratory Tract ◽

Autoimmune Process ◽

Thrombocytopenic Purpura ◽

Coronavirus Infection ◽

Upper Respiratory

Immune thrombocytopenic purpura (ITP) is an autoimmune disorder that causes isolated thrombocytopenia. Many viruses have been identified as triggering the autoimmune process, including HIV, MCV, EBV, parvovirus, rubella and measles. However, ITP in association with coronavirus infection has not previously been reported. We describe the case of a healthy man who presented with severe ITP complicated by intracranial haemorrhage following upper respiratory tract infection. An infection screen revealed coronavirus infection.

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An analysis of the clinical picture of respiratory tract infections in primary care patients

Pediatria i Medycyna Rodzinna ◽

10.15557/pimr.2020.0069 ◽

2020 ◽

Vol 16 (4) ◽

pp. 382-388

Author(s):

Aneta Rzepka ◽

◽

Anna Mania ◽

Keyword(s):

Tract Infection ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Respiratory Tract Infections ◽

Viral Infections ◽

Upper Respiratory Tract ◽

Lower Respiratory Tract Infections ◽

Upper Respiratory ◽

Tract Infections

Aim: The aim of this study was to analyse the clinical picture of respiratory tract infections among adult patients visiting their general practitioners. Materials and methods: The analysis included 301 adult patients who reported to their general practitioners due to respiratory tract infection. W assessed clinical symptoms, age, final diagnosis, probable aetiology, additional tests, including Actim® Influenza A&B rapid test to confirm influenza infection, radiographic and laboratory findings, as well as comorbidities, treatment used, vaccinations against influenza, and smoking habits. Results: Upper respiratory tract infections accounted for the vast majority of cases (74%), and these primarily included viral infections (62%), some of which required a change of therapy (23%) due to suspected secondary bacterial infection; lower respiratory tract infections accounted for 26% of cases. The main symptoms reported by the patients included cough, pharyngeal pain, fever, rhinitis, general malaise, nasal obstruction, headache, muscle pain and dysphonia. Acute pharyngitis was the dominant diagnosis (27%), followed by acute upper respiratory tract infection of multiple sites (13.6%), acute nasopharyngitis (known as common cold) (10%), purulent tonsillitis (11.6%), acute bronchitis (11%) and influenza (11%). Antibiotic therapy was used in 60% of patients with upper respiratory tract infection and 68% of patients with lower respiratory tract infection. Conclusions: The majority of patients were diagnosed with viral infections. The highest incidence of respiratory tract infections was observed in elderly individuals and patients with chronic cardiovascular diseases, lung diseases, diabetes mellitus and cancer. Smokers are more likely to develop lower respiratory tract infections (confirmed by additional tests) compared to other groups of patients. Individuals vaccinated against influenza account for a small proportion of patients.

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A CASE OF CLINICAL ITP IN A PATIENT WITH COVID19

10.36106/ijsr/2305358 ◽

2021 ◽

pp. 76-77

Author(s):

Shivani Dalsaniya ◽

Ishan Desai ◽

Janak Khambholja ◽

Paltial Palat ◽

Nehal Shah

Keyword(s):

Tract Infection ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Kidney Injury ◽

Upper Respiratory Tract ◽

Thrombocytopenic Purpura ◽

Rare Association ◽

Upper Respiratory ◽

Multi Organ Dysfunction Syndrome

Since December 2019, China has experienced an outbreak of SARS COV2 known as Coronavirus Disease or COVID19.Subsequently it led to pandemic all across the globe. SARS-COV-2 is known to present with a variety of manifestations ranging from a completely asymptomatic course or a mild URTI (Upper respiratory tract infection) to a full blown LRTI (Lower Respiratory Tract Infection) with ARDS (Acute Respiratory Disease Syndrome) like features, ALIs (Acute Lung Injury), Pulmonary or Pan-endothelitis, overwhelming rapidly escalating Cytokine Storm, Multi-Organ Dysfunction Syndrome (MODS), Stroke, Encephalitis, Myocarditis, Septicemia, Acute Kidney Injury, Septic shock and several other complications(2). Here we report a rare association of SARS-COV2 infection with Immune Thrombocytopenic Purpura.

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Exposure to cold and acute upper respiratory tract infection

Rhinology Journal ◽

10.4193/rhino14.239 ◽

2015 ◽

Vol 53 (2) ◽

pp. 99-106

Author(s):

R. Eccles ◽

J.E. Wilkinson

Keyword(s):

Body Temperature ◽

Tract Infection ◽

Respiratory Tract ◽

Body Surface ◽

Viral Infections ◽

The Body ◽

Cold Weather ◽

Upper Respiratory Tract ◽

Cold Air ◽

Upper Respiratory

The incidence of acute upper respiratory tract viral infections (URTI) is directly correlated to air temperature with most URTI occurring seasonally in cold weather. This review looks at four types of cold exposure and examines the evidence and possible mechanisms for any relationship to URTI. The effects of cold are discussed as: 1) Chilling of the nose and upper respiratory tract by breathing cold air, 2) Chilling of the mouth and upper digestive tract by ingestion of cold drinks and food, 3) Acute chilling of the body surface, and, 4) Chilling of the body as a whole with a fall in body temperature, hypothermia. Some studies were found to support a relationship between breathing cold air and chilling the body surface with the development of URTI, although this area is controversial. No evidence was found in the literature to support any relationship between ingestion of cold drinks and food and URTI, and similarly no evidence was found to link hypothermia and URTI.

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