Ipecac Use in the Home

PEDIATRICS ◽  
1985 ◽  
Vol 75 (6) ◽  
pp. 1148-1148
Author(s):  
BARRY H. RUMACK
Keyword(s):  
Medical Literature ◽  
Individual Researcher ◽  
Poison Centers

The two articles concerning syrup of ipecac in the home (appearing in this issue of Pediatrics) raise and partially answer some questions of importance to pediatricians and poison centers. As is constant in the medical literature, additional questions are raised which provide grist for other studies. It seems unlikely that we will ever run out of questions and completely "solve" the quandries of pediatrics or poisoning. Both studies rely on the telephone management and follow-up of patients. This admittedly results in secondhand data and can never be as good as that which an individual researcher observes. It is, however, "real" in that poison centers and pediatricians operate in this way much of the time.

A Blueprint for Undergraduate Students to Work on Medical Cases (Preprint)

2021 ◽  
Author(s):  
Alhad Mulkalwar
Keyword(s):  
Case Report ◽  
Undergraduate Students ◽  
Formal Education ◽  
Medical Literature ◽  
Medical Problem ◽  
Evidence Based ◽  
Medical Progress ◽  
Based Medicine ◽  
Publishable Case Report

UNSTRUCTURED A case report is a detailed narrative that describes the symptoms, signs, diagnosis, treatment, and follow-up of a medical problem of an individual patient. They usually describe an unusual or novel occurrence and although they lie at the bottom of the hierarchy of the Evidence Based Medicine Pyramid, they still remain one of the cornerstones of medical progress and provide key additions to the existing medical literature. Unfortunately, abysmally few physicians-in-training receive a formal education regarding what constitutes a publishable case report. The article throws light on this aspect of medical education

Demystifying Biclonal Gammopathy: A Pathologist’s Perspective

2019 ◽  
Vol 50 (4) ◽  
pp. 357-363 ◽  
Author(s):  
Sudha Sharma ◽  
Parikshaa Gupta ◽  
Ritu Aggarwal ◽  
Pankaj Malhotra ◽  
Ranjana Walker Minz ◽  
...  
Keyword(s):  
Medical Literature ◽  
Case Reports ◽  
Care Center ◽  
Tertiary Care ◽  
Protein Electrophoresis ◽  
Disease Course ◽  
Immunofixation Electrophoresis ◽  
Biclonal Gammopathy ◽  
Monoclonal Proteins

Abstract Background The production of 2 monoclonal proteins characterizes biclonal gammopathic manifestations (BGMs). The available medical literature from India is chiefly restricted to case reports. Objective To study the incidence of BGMs in a tertiary care center in Chandigarh, India, during a 4-year period. We evaluated these cases further for their laboratory characteristics. Methods We scrutinized the contents of a database containing information from the studied 4-year period. Cases reported as BGMs on serum protein electrophoresis (SPEP) and confirmed by serum immunofixation electrophoresis (SIFE) were included. Results A total of 15 cases, from a cohort of 914 cases of monoclonal gammopathic manifestations (MGMs), were available. On SPEP, 2 M bands were observed in 12 cases. On SIFE, 4 cases were reported as being of true BGMs. The most common heavy-chain combination observed was immunoglobulin (Ig)A-IgG. Follow-up was available in 2 patients. Conclusion Identification of BGMs increases diagnostic precision, despite that the treatment is similar to that for monoclonal gammopathic manifestations (MGMs). BGMs can be transitory and may be observed at presentation or during the disease course.

Poison Centers: An Overview of the Past, Present, and Future

2000 ◽  
Vol 13 (1) ◽  
pp. 14-26
Author(s):  
Rose Ann Gould Soloway
Keyword(s):  
Health Care Providers ◽  
Clinical Course ◽  
Future Research ◽  
Care Providers ◽  
Need For Treatment ◽  
The Past ◽  
Poison Centers ◽  
Poison Prevention

Poison centers are the source of expert treatment advice for all types of poison exposures. For this reason, health care providers and consumers are encouraged to call poison centers immediately in case of a possible poison exposure. This allows for rapid evaluation of potential toxicity, determination of the need for treatment, follow-up to the conclusion of a patient's clinical course, and data collection which can be useful in identifying unsuspected poisons, directing future research, and identifying subjects for poison prevention efforts.

Comparison of real prognosis and estimated prognosis by Adjuvant! Online in breast cancer in sites of Itajaí, Brazil.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e12035-e12035
Author(s):  
Giuliano Santos Borges ◽  
Evandro De Azambuja ◽  
Rodrigo Rovere ◽  
Paulo Henrique Colchon ◽  
Marcos Cesar Staak Junior
Keyword(s):  
Breast Cancer ◽  
External Validity ◽  
Cancer Survival ◽  
Medical Literature ◽  
Breast Cancer Survival ◽  
Number Of Patients ◽  
The One ◽  
Post Hoc ◽  
Disease Free

e12035 Background: Internet-available programme Adjuvant! Online is widely regarded as one of the best tools to estimate prognosis as well as benefit of adjuvant therapy in breast cancer. Methods: It is a retrospective cohort study, with a post hoc analysis with 214 patients of three different Brazilian services in which were measured the year overall and disease free survivals in a follow up of three years, and the same endpoints were estimated on a 10 year basis by the Adjuvant! Online programme. Results: See table. Conclusions: Our study shows interesting trends in breast cancer survival, even though the number of patients accrued may not be enough to have full external validity. We conclude that the OS and DFS rates in our sample compared to the one calculated by the Adjuvant! Online programme display agreement, following the same pattern, considering different periods of follow up (much longer in the internet tool). The only group which had poor concordance was the group of younger patients (i.e., under 40), even though it was the least represented group in our sample. Nevertheless, it can be suggested that the programme underestimates the usually bad prognosis in these cases, as broadly documented in medical literature. Our study shows interesting trends in breast cancer survival, even though the number of patients accrued may not be enough to have full external validity. [Table: see text]

Eustachian Tube Bypass: Experimental Evidence for Total Eustachian Tube Substitution

1978 ◽  
Vol 86 (3) ◽  
pp. ORL-498-ORL-505
Author(s):  
Abraham Lapidot ◽  
Dessaglegn Terrefe ◽  
Firooz Rezvani ◽  
Aubrey J. Hough
Keyword(s):  
Experimental Evidence ◽  
Clinical Experience ◽  
Eustachian Tube ◽  
Middle Ear ◽  
Medical Literature ◽  
Severe Inflammation ◽  
Ascending Infection

Several preliminary reports have appeared in the medical literature in respect to eustachian tube substitution1–6 since Zollner7 first described his inability to open the obstructed eustachian tube. These procedures3,5,6 have the disadvantage that the distal end of the eustachian tube substitute is inaccessible by other than another operation. This paper is a follow-up report to our clinical experience.2 The purpose of the experiment was to determine whether the middle ear was ventilated by the tympano-oropharyngeal substitute eustachian tube and whether ascending infection occurred. Fourteen ears underwent eustachian tube substitution. The natural eustachian tubes of these ears were obliterated three to five months after eustachian tube substitution had been performed. The animals were killed three to four months after obliteration of the natural eustachian tubes. Studies of the decalcified sections showed an absence of infection in six of the ears, with mild to severe inflammation in the rest of the specimens.

scholarly journals Multiple Doses of Icatibant used during Pregnancy

2017 ◽  
Vol 8 (3) ◽  
pp. ar.2017.8.0210 ◽  
Author(s):  
Lauren W. Kaminsky ◽  
Theodore Kelbel ◽  
Fay Ansary ◽  
Timothy Craig
Keyword(s):  
Adverse Events ◽  
Literature Search ◽  
Medical Literature ◽  
Case Reports ◽  
Treatment Options ◽  
Multiple Treatment ◽  
Multiple Doses ◽  
Healthy Infants

Background Hereditary angioedema (HAE) is a life-long disease that often manifests by puberty. Treatment of attacks is essential to improve quality of life and to decrease morbidity and mortality. During pregnancy, treatment is limited because multiple treatment options, including icatibant, are not approved for use during pregnancy. Objective We report the outcomes of three pregnancies during which icatibant was used by a patient with HAE with normal C1-inhibitor for treatment of attacks. We also reviewed the literature for reports of icatibant use during pregnancy for outcomes and adverse events. Methods We report on a patient who treated herself with icatibant during three separate pregnancies. Postpartum follow-up verified the health of the mother and children. We also performed a complete literature search of medical literature data bases on icatibant use during pregnancy. Results The patient in our report administered multiple doses of icatibant during three pregnancies. The child born from the first pregnancy and the child from the third pregnancy were born at term and without congenital anomalies. The child from the second pregnancy was 1-month preterm. All three children were developmentally normal. The literature search identified two case reports and one abstract of limited icatibant use without adverse events during pregnancy in patients with HAE. These pregnancies resulted in the births of healthy infants. Conclusion From a search of the literature, three cases of icatibant use during pregnancy resulted in healthy infants. In addition, we report that from icatibant use in three separate pregnancies, one infant was born prematurely, but there were no birth defects. From follow-up, the children continued meeting developmental milestones. This report adds to the acquisition of knowledge for drug adverse events during postmarketing surveillance for icatibant use during pregnancy.

scholarly journals Prevention of pathological fracture in fibrous dysplasia of proximal femur in a 24-year-old female a rare presentation - a case report

2021 ◽  
Vol 7 (6) ◽  
pp. 1238
Author(s):  
Amit Supe ◽  
Jayesh Mhatre ◽  
Nihar Modi
Keyword(s):  
Case Report ◽  
Fibrous Dysplasia ◽  
Pathological Fracture ◽  
Medical Literature ◽  
Favourable Outcome ◽  
Endocrine Dysfunction ◽  
Rare Presentation ◽  
Café Au Lait Spots ◽  
Hip Screw

<p class="abstract">Fibrous dysplasia (FD) was historically mentioned in the medical literature in 1938 by Dr. Lichtenstein and in 1942 by Dr. Lichtenstein and Jaffe. The term Jaffe-Lichtenstein syndrome is sometimes used synonymously with monostotic FD or to denote cases of polyostotic FD with café au lait spots, but no endocrine dysfunction. Our case is a 24-year-old female, housewife presented to our hospital with a complaints of right hip pain and backache with difficulty in walking of 6 months duration. She had dull aching pain which increased in intensity with the course of time, there was no radiation, but was aggravated by movements. She was managed with dynamic hip screw along with curettage of the lesion and bone graft, after 9 months of follow up, she had no pain over her hip and there was calcification over the previous lesion, our patient had a very favourable outcome.</p>

Return to play in children with shunted hydrocephalus

2021 ◽  
pp. 1-9
Author(s):  
Agnieszka Stanuszek ◽  
Adam Bębenek ◽  
Olga Milczarek ◽  
Stanisław Kwiatkowski
Keyword(s):  
Medical Literature ◽  
Univariate Analysis ◽  
Young Patients ◽  
Return To Play ◽  
Neurological Deficits ◽  
Before And After ◽  
Sport Activities ◽  
Neurosurgical Treatment ◽  
Low Incidence

OBJECTIVE The objective of this study was to assess the relevance of shunted hydrocephalus in regard to participation by young patients in physical education (PE) classes. Students diagnosed with this condition are very often restricted in PE classes owing to the lack of official and well-defined guidelines. However, the medical literature suggests that there is no relationship between the disease and risk of sport-related injuries. In this study, the authors intended to evaluate not only the accuracy of this statement, but also to explore the factors that delay or foreclose return to exercise. METHODS The analysis was conducted on patients aged < 18 years with a diagnosis of shunt-treated hydrocephalus who received follow-up for a minimum of 1 year. Collected medical data were examined for factors limiting participation in PE at school. Indicators of both sport-related injuries and conditions acceptable for return to exercise were gathered during follow-up visits. RESULTS In this study, 72.72% of patients attended sport activities in schools. The group based on return to PE class differed significantly in the occurrence of neurological deficits, as well as presence of comorbidities. In univariate analysis, the authors identified these parameters as risk factors limiting participation in PE. On the contrary, etiology of hydrocephalus, type of shunting device, number of shunt malfunctions, and presence of epilepsy did not significantly influence sport engagement. CONCLUSIONS This study shows that many patients with shunt-treated hydrocephalus can safely participate in PE. Presence of neurological deficits before and after neurosurgical treatment, as well as presence of comorbidities, are factors that negatively impact the possibility of a patient returning to physical activity. Sport-related injuries do occur, but at a low incidence.

Patterned Trichoteiromania in Androgenetic Alopecia

2021 ◽  
pp. 1-4
Author(s):  
Luis E. Sánchez-Dueñas ◽  
Leslie E. Rocha-Méndez ◽  
Lidia Rudnicka
Keyword(s):  
Psychiatric Disorders ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Medical Literature ◽  
Androgenetic Alopecia ◽  
Distressing Condition

Trichotillomania is the most frequent reported cause of self-inflicted hair disorders, within which are included trichoteiromania, trichotemnomania, and trichocryptomania, also known as trichorrexomania. These conditions are commonly described in the context of psychiatric disorders. Nevertheless, there exists reports in otherwise healthy patients that suffer a form of no cicatricial alopecia, such as alopecia areata. We communicate 3 cases of male androgenetic alopecia with patterned miniaturization that coexisted with trichoscopic findings of trichoteiromania. The presence of brush-like ends or broom hairs is a highly suggestive feature of this entity. To the best of our knowledge, this association was not previously reported in the medical literature. The possibility of self-induced hair loss should be kept in mind during every follow-up visit in all types of alopecia, remembering that hair loss itself is already a distressing condition.

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