scholarly journals Major Depressive Disorder Association with Unsuccessful In-Vitro Fertilization (IVF) of Primary Infertile Women

2019 ◽  
Author(s):  
Shalan Joodah Rhemah Al-Abbudi, M.B., Ch.B. F.I.B.M.S.Psych.
Keyword(s):  
Depressive Disorders ◽  
Cross Sectional Study ◽  
Mental Illnesses ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Infertile Women ◽  
Increased Risk ◽  
High Prevalence ◽  
Self Reporting Questionnaire

Background: Women who go through unsuccessful IVF treatment were at increased risk of depressive disorders. Objective: investigate the association between the unsuccessful IVF and depression among women with primary infertility. Methods: a cross-sectional study included infertile women attending fertility center. Socio-demographic and clinical variables were compiled. Self-Reporting Questionnaire (SRQ-20) to identify mental illnesses; DSM-V criteria for depression and Hamilton-17 Scale for severity of depression, were used. Results: high prevalence of depression among infertile women 80%. Unsuccessful IVF were 46%. About 26 % of infertile women with unsuccessful IVF were depressed. Depression was significantly associated with education, monthly income, duration of marriage, smoking, medication, chronic illness, and religion. Conclusion: Depressive disorders are the most frequently observed disorder among infertile women exposed to unsuccessful IVF

scholarly journals Evaluation of uterine cavity by hysteroscopic examination in infertile women in BSMMU

2016 ◽  
Vol 9 (1) ◽  
pp. 32 ◽  
Author(s):  
Jesmine Banu ◽  
Farzana Deeba ◽  
Parveen Fatima ◽  
Parveen Sultana
Keyword(s):  
Standard Procedure ◽  
Uterine Cavity ◽  
Cross Sectional Study ◽  
Infertile Woman ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Infertile Women ◽  
Primary Infertility ◽  
Diagnostic Hysteroscopy

<p><strong>Background:</strong> Hysteroscopy is the gold standard procedure for uterine cavity exploration. However, hysteroscopy is only recommended by the WHO when clinical or complementary exams (ultrasound, HSG) suggest intrauterine abnormality or after in vitro fertilization failure. Nevertheless, many specialists feel that hysteroscopy is a more accurate tool.</p><p><strong>Objec­tive:</strong> The aim of this prospective study is to find out the evaluation of uterine cavity by hysteroscopic examination as a primary workup of infertility. To asses the uterine pathology which is the causal factor for infertility.</p><p><strong>Method:</strong> This is a cross sectional study in which total 100 infertile patients were enrolled from infertility OPD in BSMMU with maintain­ing inclusion and exclusion criteria Hysteroscopy was performed with a standard sequence. The endocervical canal, uterine cavity, endometrium, and tubal ostia were inspected and findings were recorded. Results: Hysteroscopy was performed in 100 infertile women,among them 44% were presented with primary infertility and 56% presented with secondary infertility. The most common indication for diagnostic hysteroscopy was as a part of an infertility workup 80% cases. Other indication included abnormal hysterosalphingography, recurrent pregnancy loss and unexplained infertility. Hysteroscopy revealed a normal uterine cavity in 51 ( 51 % ) women (Table 2).among them majority of patients were primary infertility.and age less than 30 years. Hysteroscopic abnormalities are significantly high in secondary than primary infertility.</p><p><strong>Conclusion:</strong> In this study abnormal hysteroscopic findings were found in 49% who underwent diagnostic hysteroscopy. Our data are an additional argument to suggest that diagnostic hysteroscopy as part of investiga­tion in infertile woman to evaluate uterine pathology. Routine diagnostic hysteroscopy should be part of an infertility workup in both primary and secondary infertility.At the same setting therapeutic approach also be possible which is beneficial for the patients.</p>

scholarly journals Estimating the Risk of Monochorionic Twins in IVF Pregnancies From the Perspective of a Prenatal Diagnosis Unit

2015 ◽  
Vol 19 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Veronica Sarais ◽  
Alessio Paffoni ◽  
Giulia Maria Baffero ◽  
Fabio Parazzini ◽  
Nicola Persico ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Local Population ◽  
Cross Sectional Study ◽  
Distribution Model ◽  
Monochorionic Twins ◽  
Cross Sectional ◽  
Background Rate ◽  
Vitro Fertilization ◽  
Increased Risk

The aim of the present work was to estimate the risk of monochorionic twin (MCT) pregnancies in in vitro fertilization (IVF) cycles using data from a prenatal diagnosis unit. This was a retrospective cross-sectional study reporting on the frequency of IVF pregnancies among women attending a prenatal diagnosis service specifically dedicated to the management of monochorionic pregnancies. The observed rate was compared with the local regional rate of IVF births (2.2%). A binomial distribution model was used to calculate the 95% CI of proportions. One hundred and forty-five monochorionic pregnancies were selected. Ten of these were achieved with IVF, corresponding to a rate of 6.9% (95% CI: 3.5–11.8), significantly higher than the background rate in the local population of 2.2%. When considering exclusively monochorionic pregnancies achieving delivery of two viable newborns (n = 132), the number of IVF pregnancies was nine (6.8%, 95% CI: 3.7–12.5). We did not detect major differences in pregnancy outcome between IVF and natural monochorionic pregnancies, with the exception of the proportion of newborns with a neonatal birth < 2,500 g (100% vs. 80%, p = .03). In conclusion, data obtained from the perspective of a prenatal diagnosis unit suggest that women undergoing IVF face a 3- to 4-fold increased risk of monochorionic pregnancies.

scholarly journals Laparoscopic findings of infertile women at Bangabandhu Sheikh Mujib Medical University

2016 ◽  
Vol 7 (2) ◽  
pp. 95
Author(s):  
Shakeela Ishrat ◽  
Farzana Deeba ◽  
Jesmine Banu ◽  
Afruna Rahman Diti
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Tubal Patency ◽  
Infertile Women ◽  
Unilateral Block ◽  
Medical University ◽  
Work Up

<p><strong>Background:</strong> Laparoscopy is an important component of infertility work up. It is the gold standard for evaluation of pelvic pathology and assessment of tubal patency.<strong> Objective:</strong> The objective of the study was to analyze the laparoscopic findings of infertile women presenting at Infertlity unit of Bangabandhu Sheikh Mujib Medical University. <strong>Method:</strong> We had a retrospective cross-sectional study on Japaroscopic findings of 110 women. <strong>Results:</strong> Out of all patients 22.7% women had endometriosis. Various degrees of adhesion of pouch of Douglus was present in 16.4 %. Regarding tubal pate:1cy , 26.4% had unilateral block and 28.2% had bilateral block.<strong> Conclusion:</strong> A significant number of infertile women at the Infertility unit of BSMMU has tuboperitoneal disease and bilateral tubal block and ultimately need in vitro fertilization.</p>

scholarly journals Resilience, Perceived Stress, and Depressed Mood in Women Under in Vitro Fertilization Treatment

2021 ◽  
Author(s):  
Carmen Fernandez-Ferrera ◽  
David Llaneza-Suarez ◽  
Daniel Fernandez-Garcia ◽  
Vanesa Castañon ◽  
Cristina Llaneza-Suarez ◽  
...  
Keyword(s):  
Protective Effect ◽  
Perceived Stress ◽  
Depressed Mood ◽  
Sleep Disturbances ◽  
Depression Scale ◽  
Short Version ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Infertile Women

AbstractIt has been suggested that women who display higher resilience levels may have less psychological distress during IVF. The aim of this study was to evaluate how infertile women deal with perceived stress, depressed mood, and sleep disturbances at the first IVF attempt and after one or more negative IVF outcomes depending on their level of resilience. An observational, cross-sectional study was carried out in a sample of 207 infertile women undergoing IVF procedures. The participants completed the short version of the Connor-Davidson Resilience Scale (CD-RISC), the short version of the European Spanish Version of Perceived Stress Scale (PSS-10), the Center of Epidemiologic Studies Depression Scale (CESD-10), and the Jenkins Sleep Scale (JSS). The relationship between CD-RISC scores ranked according to percentiles and mean PSS-10 scores revealed that women with strong resilience had lower perceived stress. After splitting the sample according to CD-RISC percentiles, differences were observed only at the first IVF attempt and the observed protective effect of high resilience scores appears to disappear following a negative IVF outcome. Women with high resilience are less likely to suffer from perceived stress or depressed mood during their first IVF attempt, this protective effect appears to be lost after a negative outcome.

scholarly journals Transferrin and antioxidants partly prevented mouse oocyte oxidative damage induced by exposure of cumulus-oocyte complexes to endometrioma fluid

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Zi Ren ◽  
Jiana Huang ◽  
Chuanchuan Zhou ◽  
Lei Jia ◽  
Manchao Li ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Oocyte Retrieval ◽  
Cross Sectional Study ◽  
Human Oocyte ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Good Quality Embryo ◽  
Damage Process ◽  
Human And Mouse

Abstract Background Exposure of oocytes to the endometrioma fluid has an adverse effect on embryonic quality. To determine whether adding transferrin and antioxidants to culture medium could counteract detrimental effects on mouse cumulus-oocyte complexes (COCs) induced by exposure to endometrioma fluid or not, we conducted an in vitro cross-sectional study using human and mouse COCs. Methods Eighteen women who had their oocytes exposed to endometrioma fluid during oocyte retrieval were enrolled. COCs from superovulated ICR female mice were collected. They were first exposed to human endometrioma fluid and then treated by transferrin and/or antioxidants (cysteamine + cystine). Subsequently, COCs function was assessed by molecular methods. Results This study observed that human COCs inadvertently exposed to endometrioma fluid in the in vitro fertilization (IVF) group led to a lower good quality embryo rate compared to intracytoplasmic sperm injection (ICSI) group. Exposure of mouse COCs to endometrioma fluid accelerated oocyte oxidative damage, evidenced by significantly reduced CCs viability, defective mitochondrial function, decreased GSH content and increased ROS level, associated with the significantly higher pro-portion of abnormal spindles and lower blastocyst formation (p < 0.05, respectively). This damage could be recovered partly by treating COCs with transferrin and antioxidants (cysteamine + cystine). Conclusions Transferrin and antioxidants could reduce the oxidative damage caused by COCs exposure to endometrioma fluid. This finding provides a promising new possibility for intervention in the human oocyte oxidative damage process induced by endometrioma fluid during oocyte pick-up.

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

2016 ◽  
Vol 32 ◽  
pp. 222-226 ◽  
Author(s):  
Dan Chen ◽  
Jing Ping Zhang ◽  
Ling Jiang ◽  
Huayan Liu ◽  
Ling Shu ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Chinese Men

scholarly journals Factors Related to the Number of Antral Follicles on InVitro Fertilization (IVF)

2016 ◽  
pp. 75
Author(s):  
Fransiskus C Raharja ◽  
Ketut Suwiyoga ◽  
IPG Wardhiana
Keyword(s):  
Prevalence Ratio ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Antral Follicles ◽  
Chi Square Test ◽  
The Mean ◽  
Infertile Patients

Objective: To determine factors which are related to the number of antral follicles on infertile patients. Method: This cross sectional study was conducted in In-Vitro Fertilization (IVF) clinic of Graha Tunjung, Sanglah hospital, Bali. All fertile patients following the IVF program were calculated the number of antral follicles in both ovarian using transgene USG. This sample was recruited by random sampling from April 1st, 2001 to April 30th, 2011. We analyzed the data using Chi square test through SPSS for Windows 17.0 version. Result: Of 102 samples, the mean of patients’ age was 32.9% (SD 4.6) years old. From 72 patients (70.6%) experienced above 3 years of infertile period, the primary infertile was on 69 patients (67.7%). There was a relationship between patients’ age and the number of antral follicles significantly (prevalence ratio (PR) 1.41; 95% CI 1.11- 1.79). Meanwhile, the number of antral follicles and type of infertile (PR 1.02; 95% CI 0.76-1.37) also infertile period (PR 0.95; 95% CI 0.72-1.27) were not associated significantly. Conclusion: Patients’ age has an association with the number of antral follicles on IVF. [Indones J Obstet Gynecol 2016; 4-2: 75-77] Keywords: age, infertile, infertile period, number of antral follicles and type of infertile

scholarly journals Basal follicle stimulating hormone and leptin on the day of hCG administration predict successful fertilization in in vitro fertilization

2016 ◽  
Vol 25 (1) ◽  
pp. 39-43 ◽  
Author(s):  
Andon Hestiantoro ◽  
Budi Wiweko ◽  
Robert H. Purwaka
Keyword(s):  
In Vitro Fertilization ◽  
Follicle Stimulating Hormone ◽  
Oocyte Retrieval ◽  
Cross Sectional Study ◽  
Mature Oocyte ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Fertility Clinic ◽  
Stimulating Hormone

Background: Successful pregnancy in in vitro fertilization (IVF) program depends on multiple factors. This study aimed to determine whether age, body mass index (BMI), basal follicle stimulating hormone (FSH), estradiol, and leptin on the day of trigger ovulation with human chorionic gonadotropin (hCG) might be used as predictor for successful oocyte fertilization in in vitro fertilization (IVF) program.Methods: This is a cross sectional study conducted in Yasmin Fertility Clinic, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Forty participating patients underwent IVF program, excluding smokers, patients with diabetic, morbid obesity, and severe oligospermia or azoospermia. Age, BMI, basal FSH, estradiol, leptin on the day of hCG administration, oocyte count on oocyte retrieval, the number of mature oocyte, and fertility rate were analyzed using bivariate and multivariate analysis to determine which eligible factors play role in predicting the successful of fertilization.Results: Significant correlation was found between basal FSH level and serum leptin/oocyte ratio on the day of hCG administration with successful fertilization. We found probability formula as follows: 1/(1+exp –(6.2 - 0.4(leptin serum/oocyte ratio) - 0.8(basal FSH)), with 77.8% sensitivity, 77.8% specificity, and AUC levels of 85.6% indicating strong predictability. Probability of successful fertilization related to basal FSH level of 5.90 mIU/mL and leptin serum/oocyte ratio of 3.98.Conclusion: The formula consisting of basal FSH and leptin serum/oocyte ratio on the day of trigger ovulation was capable in predicting the probability of successful fertilization in IVF procedure.

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