scholarly journals Depression among predictors of intermittent claudication: A cross-sectional study

2021 ◽  
Author(s):  
Gergely Tóth-Vajna ◽  
Zsombor Tóth-Vajna ◽  
Barna Konkoly Thege ◽  
Piroska Balog
Keyword(s):  
Risk Factors ◽  
Intermittent Claudication ◽  
Depressive Symptomatology ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Hazardous Drinking ◽  
Binary Logistic Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Traditional Risk Factors

Abstract Purpose The aim of the present cross-sectional study was to investigate the relationship between depression and intermittent claudication (IC), independently of traditional risk factors. Main methods The sample consisted of 300 individuals (M age = 65.3 ± 8.7 years, 61.0% female) recruited from the offices of 33 general practitioners. Participants’ medical history and the presence of major cardiovascular risk factors were recorded. Participants completed the Edinburgh Claudication Questionnaire. The role of depression (assessed by a shortened version of the Beck Depression Inventory) in predicting IC was examined using a binary logistic regression analysis – controlled for sex, age, hypertonia, diabetes, smoking, hypercholesterinemia, hazardous drinking, and body mass index (BMI). Results The descriptive data indicated that the prevalence of depression was 57.9% in the IC subgroup and 16.1% in those free of IC. The bivariate analyses indicated that hypercholesterinemia, smoking, hazardous drinking, BMI, and depression were significantly associated with IC. Male sex and age showed a trend toward being a significant correlate of IC. Results of the multivariate analyses indicated that depressive symptomatology was significant in predicting IC (OR: 1.08 (1.05–1.11)), even after controlling for lifestyle and traditional risk factors such as smoking, hazardous drinking, and BMI. Among traditional risk factors, smoking (OR: 2.44 (1.26–4.74)), hazardous drinking (OR: 1.19 (1.02–1.40)), and hypercholesterinemia (OR: 2.17 (1.26–3.75)) showed a significant, positive relationship with IC. Conclusions These results underscore the importance of a multidisciplinary approach that focuses on supporting health-related behavioral changes and managing mental health symptoms when providing care for patients with IC.

scholarly journals Correlation of Lipid Ratios With the Severity of Pulmonary Alveolar Proteinosis: A Cross-Sectional Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Xin Yan ◽  
Yujuan Gao ◽  
Qi Zhao ◽  
Xiaohua Qiu ◽  
Mi Tian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Alveolar Proteinosis ◽  
Pulmonary Function Tests ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Control Group ◽  
Binary Logistic Regression Analysis ◽  
Cross Sectional ◽  
Lipid Ratios ◽  
Alveolar Proteinosis

Background: Lipids are known to accumulate abnormally in the alveoli and circulate during pulmonary alveolar proteinosis (PAP). However, the relationship between lipid ratios and PAP is not clear. In this study, we investigated the lipid ratios in PAP patients and explored the relationships between lipid ratios and the severity of PAP.Methods: A total of 122 PAP patients were diagnosed and divided the mild- moderate PAP group (n = 61) and the severe PAP group (n = 61) according to the value of disease severity score (DSS). One hundred thirty healthy volunteers were classified as the control group. Routine blood examination and pulmonary function tests were performed and lipid profile were measured.Results: Compared with the control group, patients with PAP had significantly higher TG, TC/HDL-C, TG/HDL-C, and non-HDL-C, while lower HDL-C (all P < 0.05). Patients with the severe PAP had higher TC, TG, LDL-C, TC/HDL-C, and non-HDL-C, while lower HDL-C than patients with the mild- moderate PAP (all P < 0.05). Binary logistic regression analysis indicated that TC/HDL-C (OR = 2.322, 95% CI 1.621–3.713, P = 0.024) and non-HDL-C (OR = 1.797, 95% CI 1.239–3.109, P = 0.036) were all significantly correlated with the severity of PAP after adjustment for other risk factors. The AUC value of TC/HDL-C for predicting the severity of PAP was larger than that of non-HDL-C. The AUROC for TC/HDL-C was 0.741 (0.654–0.828), and the optimal cut-off point for TC/HDL-C was 5.05 (sensitivity: 73.6%, specificity: 68.1%).Conclusions: Lipid ratios, including TC-HDL-C and non-HDL-C, were independent risk factors for the severity of PAP. TC/HDL-C is a promising biomarker for the severity of PAP.

scholarly journals The Association Between Dietary Antioxidant Micronutrients and Cardiovascular Disease in Adults in the United States: A Cross-Sectional Study

2022 ◽  
Vol 8 ◽  
Author(s):  
Ting Yin ◽  
Xu Zhu ◽  
Dong Xu ◽  
Huapeng Lin ◽  
Xinyi Lu ◽  
...  
Keyword(s):  
Therapeutic Option ◽  
Logistic Models ◽  
Binary Logistic Regression ◽  
The United States ◽  
Cross Sectional Study ◽  
Binary Logistic Regression Analysis ◽  
Sectional Study ◽  
Dietary Antioxidants ◽  
Cross Sectional ◽  
Dietary Antioxidant

Background: Antioxidant micronutrients represent an important therapeutic option for the treatment of oxidative stress-associated cardiovascular diseases (CVDs). However, few studies have evaluated the relationship between the levels of multiple dietary antioxidants and CVDs.Objective: The study therefore aimed to evaluate associations between dietary antioxidants and total and specific CVDs among a nationally representative sample of adults in the US.Design: In total, 39,757 adults (>20 years) were included in this cross-sectional study from the 2005–2018 National Health and Nutrition Examination Survey. We analyzed dietary recall of 11 antioxidant micronutrients in this population. Multivariate logistic and weighted quantile sum (WQS) regression were both applied to examine the relationships between these antioxidants, alone and in combination, with the prevalence of all CVDs and specific CVDs. The linearity of these correlations was also explored using restricted cubic spline (RCS) regression.Results: Multivariate logistic models showed that, compared with the lowest quartile, the levels of 11 antioxidants in the highest quartile were independently associated with decreased total CVD (all P < 0.05). The WQS index showed that, when considered together, the 11 micronutrients were negatively correlated with total CVD (P < 0.001) and five specific CVDs (all P < 0.05), and selenium had the strongest association (weight = 0.219) with total CVD. Moreover, the RCS model demonstrated that iron, zinc and copper were all negatively and non-linearly correlated with total CVD, while the eight other micronutrients had non-significant, linear, negative relationships with total CVD (P for non-linearity >0.05). A piecewise binary logistic regression analysis showed that the inflection points in the relationships between CVD and iron, zinc and copper were 7.71, 6.61, and 0.74 mg/day, respectively.Conclusions: Our findings suggested that high levels of combined dietary antioxidant micronutrients are associated with decreased prevalence of CVDs, and that selenium has the greatest contribution to this association.

scholarly journals Associations of presence or absence of exercise and/or physical activity with non-restorative sleep by gender and age: a cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e025730 ◽  
Author(s):  
Tomoo Hidaka ◽  
Shota Endo ◽  
Hideaki Kasuga ◽  
Yusuke Masuishi ◽  
Takeyasu Kakamu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Healthcare Providers ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Binary Logistic Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bodily Movement ◽  
Gender And Age ◽  
Restorative Sleep

ObjectivesNon-restorative sleep (NRS) is related to qualitative aspects of sleep. The associations of NRS with exercise (EX; a planned and purposeful activity) and physical activity (PA; daily bodily movement) by gender and age have not yet been clarified. We investigated the associations of EX and/or PA with NRS by gender and age.DesignA cross-sectional study.SettingThe data on gender, age, presence of NRS and engagement in EX and/or PA were obtained from database and questionnaire of specified medical check-ups in FY 2013 in Japan. The analysis was conducted in 2017.ParticipantsThe subjects comprised 90 122 residents (38 603 males and 51 519 females), aged 40–74 years, who had completed the specified medical check-ups.Outcome measureThe presence of NRS was assessed using a question asking whether or not the subjects usually got enough sleep. NRS was considered to be present when the subjects answered ‘No’. Binary logistic regression analysis was used to assess the associations of presence or absence of EX and/or PA with NRS. The OR and 95% CI of NRS prevalence were calculated and compared between those engaged in both EX and PA and the others.ResultsExcept for 40s and 70s among males and 40s and 50s among females, the absence of EX or PA was associated with higher ORs of NRS than referent. ORs were more than twice compared with the referents in males in their 50s (OR 2.030(95% CI 1.675 to 2.459)) and 60s (OR 2.148(95% CI 1.970 to 2.343)) and females in their 60s (OR 2.142(95% CI 1.994 to 2.302)) when they engaged in neither EX nor PA.ConclusionsHealthcare providers must take into account the similarities and differences in the associations of EX and/or PA with NRS by gender and age when they support people with NRS.

scholarly journals Factors Affecting Voluntary HIV Testing among General Adult Population: A Cross-Sectional Study in Sarawak, Malaysia

2020 ◽  
Author(s):  
Aren Sinedeh Lemin ◽  
Md Mizanur Rahman ◽  
Cliffton Akoi Pangarah ◽  
Andrew Kiyu
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Hiv Testing ◽  
Logistic Regression Analysis ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Binary Logistic Regression Analysis ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hiv Aids

Objective: Voluntary HIV testing is one of the key strategies in the HIV/AIDS prevention and control program. New National Strategic Plan for 2016-2030 in Malaysia, adapt three zeros viz. ‘zero new infections of HIV/AIDS, zero discrimination and zero AIDS-related deaths’. This study aimed to determine the predictors of voluntary HIV testing in Sarawak. Materials and methods: A cross-sectional study was conducted with a total of 900 respondents (450 males and 450 females) from the state of Sarawak, aged 18 years and above, who were selected by gender-stratified multistage cluster sampling. Data were obtained by face-to-face interview using a pretested questionnaire. Binary logistic regression analysis was done to determine the potential predictors for voluntary HIV testing. Results: The prevalence of HIV testing was higher among female respondents (26%) compared to male respondents (14.2%), and the difference was statistically significant (p < 0.001). Binary logistic regression analysis revealed that household income more than MYR 1501 (p = 0.009), not living with a partner (p < 0.001) and discussion on HIV/AIDS (p = 0.019) appeared to be predictors for the male respondents, while, ethnicity was statistically significant for female respondents (p < 0.001). Conclusion: The utilisation of HIV testing was low in both males and females. Thus, the finding of this study could be considered when designing HIV education and screening program in Sarawak.

Prevalence and Extrinsic Risk Factors for Dental Erosion in Adolescents

2017 ◽  
Vol 41 (2) ◽  
pp. 102-111 ◽  
Author(s):  
Ana C Mafla ◽  
Ximena A Cerón-Bastidas ◽  
Maria E Munoz-Ceballos ◽  
Diana C Vallejo-Bravo ◽  
Maria C Fajardo-Santacruz
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Binary Logistic Regression ◽  
Dental Erosion ◽  
Cross Sectional Study ◽  
Binary Logistic Regression Analysis ◽  
Cross Sectional ◽  
Risks Factors ◽  
Middle Adolescence ◽  
Extrinsic Risk

Objective: This manuscript examined the prevalence and extrinsic risk factors for dental erosion (DE) in early and middle adolescents in Pasto, Colombia. Study design: Dental erosion was evaluated in a random sample of 384 individuals aged 10–15 years attending three primary and high schools in this cross-sectional study. Clinical dental assessment for DE was done using O'Sullivan index. Data on general sociodemographic variables and extrinsic risks factors were obtained. Descriptive and univariate binary logistic regression analyses were performed. Results: Dental erosion was observed in 57.3% of individuals. The univariate binary logistic regression analysis showed that frequency of drinking natural fruit juices (OR 2.670, 95% CI 1.346 – 5.295, P=0.004) and their pH (OR 2.303, 95% CI 1.292 – 4.107, P=0.004) were more associated with the odd of DE in early adolescence. However, a high SES (OR 10.360, 95% CI 3.700 – 29.010, P&lt;0.001) and frequency of snacks with artificial lemon taste (OR 3.659, 95% CI 1.506 – 8.891, P=0.003) were highly associated with the risk of DE in middle adolescence. Conclusions: The results suggest that DE is a prevalent condition in adolescents living in a city in southern Colombia. The transition from early to middle adolescence implies new bio-psychosocial changes, which increase the risk for DE.

scholarly journals What is the Impact of Sex on Cardiovascular Disease Risk Factors in Patients with Chronic Kidney Diseases in China: A Cross-sectional Study

2020 ◽  
Author(s):  
Zu-feng Wang ◽  
Nan-hui Zhang ◽  
Ran Luo ◽  
Yi-chun Cheng ◽  
Kang-lin Guo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Kidney Diseases ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Chronic Kidney Diseases ◽  
Traditional Risk Factors ◽  
Wbc Count

Abstract Background: It is controversial about the sex differences in the association of chronic kidney diseases (CKD) and cardiovascular disease (CVD) risk. Thus, we examined CVD risk makers of CKD and non-CKD men and women in China, especially some “non-traditional” ones.Methods: This cross-sectional study used 7999 participants from the China Health and Nutrition Survey in 2009. This study examined the “traditional” risk factors and of CVD, such as lipoprotein cholesterol (LDL-C), total cholesterol (TC) and non-high density lipoprotein cholesterol(non-HDL-C).Also, the “non-traditional” risk factors of CVD were calculated, such as lipoprotein (a)(Lp(a)), white blood cell (WBC) count, visceral adiposity index (VAI) and lipid accumulation product (LAP).Results: Compared with men with CKD, higher levels of TC and LDL-C were observed in women with CKD. Furthermore, compared with men with CKD, the relative difference of WBC count was greater between women with CKD and their non-CKD ones. Meanwhile, the level of LAP and VAI of women with CKD were higher than men with CKD, which indicate the visceral obese. We also observed that the sex by CKD status interactions were statistically significant for TC, LDL-C, non-HDL-C, LAP, VAI and Lp(a) (all p <0.05). After adjusted the covariates, the sex differences effect on CVD risk factors among CKD patients couldn’t be eliminated as well. Conclusions: In CKD situation, women had greater lipid profiles and put on more visceral adiposity than men, which may indicate a higher CVD risk of women with CKD.

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