Modeling of Self-Assembly Dynamics of Photolithographically Patterned MUFFINS Biosensor Arrays

2007 ◽  
Vol 1002 ◽  
Author(s):  
Saul Lee ◽  
Peter Carmichael ◽  
Jason Meiring ◽  
Michael Dickey ◽  
Scott Grayson ◽  
...  
Keyword(s):  
Surface Tension ◽  
Self Assembly ◽  
Particle Density ◽  
Assembly Model ◽  
Polymer Medium ◽  
Biosensor Arrays ◽  
Capillary Interactions ◽  
Low Costs ◽  
The Individual ◽  
Flotation Behavior

ABSTRACTThe ability to mass produce biosensor arrays at low costs is an important target for the diagnostics industry. Our group has previously explored the batch production of mesoscale sized hydrogels as platforms for biosensors using photolithographic techniques. The individual hydrogel features were self-assembled through lateral capillary interactions to form a closed packed configuration and the pre-polymer medium was subsequently UV-cured to form the array. To understand the self-assembly dynamics, we investigated, through simulation, the flotation behavior of two assembling particles and its dependence on physical constants such as surface tension and particle density. Simulation results revealed that the objects tilt toward each other as they came into proximity. The tilt angle decreased with increasing surface tension but increased with increasing particle density. Understanding the details of the flotation behavior is necessary in the development of a full scale self-assembly model.

Capillary flows and self-assembly of porous hydrate structures

2012 ◽  
Vol 9 (1) ◽  
pp. 22-25
Author(s):  
S.V. Amel’kin ◽  
D.Ye. Igoshin
Keyword(s):  
Experimental Data ◽  
Aqueous Solution ◽  
Self Assembly ◽  
Capillary Flow ◽  
Secondary Crystallization ◽  
Assembly Model ◽  
Physical Processes ◽  
Good Correspondence ◽  
Solution Formation ◽  
Capillary Flows

A self-assembly model for porous hydrate structures is proposed, which takes into account the sequence of basic physical processes: hydrate growth on the surface of the aqueous solution, formation of islet structure, capillary flow, separation and transfer of secondary crystallization nuclei to the meniscus. The model was studied within the cellular automata method. A good correspondence between the results of the simulation and the experimental data is obtained.

scholarly journals Surface Activity of Humic Acid and Its Sub-Fractions from Forest Soil

2021 ◽  
Vol 13 (15) ◽  
pp. 8122
Author(s):  
Shijie Tian ◽  
Weiqiang Tan ◽  
Xinyuan Wang ◽  
Tingting Li ◽  
Fanhao Song ◽  
...  
Keyword(s):  
Surface Tension ◽  
Particle Size ◽  
Humic Acid ◽  
Forest Soil ◽  
Surface Activity ◽  
Self Assembly ◽  
Average Particle Size ◽  
Gaussian Model ◽  
Exponential Model ◽  
Average Particle

Surface activity of humic acid (HA) and its six sub-fractions isolated from forest soil were characterized by surface tension measurements, dynamic light scattering, and laser doppler electrophoresis. The surface tension of HA and its sub-fractions reduced from 72.4 mN·m−1 to 36.8 mN·m−1 in exponential model with the increasing concentration from 0 to 2000 mg·L−1. The critical micelle concentration (CMC) and Z-average particle size ranged from 216–1024 mg·L−1 and 108.2–186.9 nm for HA and its sub-fractions, respectively. The CMC have related with alkyl C, O-alkyl C, aromatic C, and carbonyl C (p < 0.05), respectively, and could be predicted with the multiple linear regression equation of CMC, CMC = 18896 − 6.9 × C-296 × alkyl C-331 × aromatic C-17019 × H/C + 4054 × HB/HI (p < 0.05). The maximum particle size was 5000 nm after filtered by a membrane with pore size of 450 nm, indicating HA and its sub-fractions could progressed self-assembly at pH 6.86. The aggregate sizes of number-base particle size distributions were mainly in six clusters including 2 ± 1 nm, 5 ± 2 nm, 10 ± 3 nm, 21 ± 8 nm, 40 ± 10 nm, and >50 nm analyzed by Gaussian model that maybe due to the inconsistency of the components and structures of the HA sub-fractions, requiring further study. It is significance to explore the surface activity of HA and its sub-fractions, which is helpful to clarify the environmental behavior of HA.

scholarly journals Interactions between an Associative Amphiphilic Block Polyelectrolyte and Surfactants in Water: Effect of Charge Type on Solution Properties and Aggregation

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1729
Author(s):  
Patrizio Raffa
Keyword(s):  
Surface Tension ◽  
Self Assembly ◽  
Interaction Model ◽  
Industrial Applications ◽  
Molecular Organization ◽  
Different Types ◽  
Solution Rheology ◽  
Interesting Class ◽  
First Time

The study of interactions between polyelectrolytes (PE) and surfactants is of great interest for both fundamental and applied research. These mixtures can represent, for example, models of self-assembly and molecular organization in biological systems, but they are also relevant in industrial applications. Amphiphilic block polyelectrolytes represent an interesting class of PE, but their interactions with surfactants have not been extensively explored so far, most studies being restricted to non-associating PE. In this work, interactions between an anionic amphiphilic triblock polyelectrolyte and different types of surfactants bearing respectively negative, positive and no charge, are investigated via surface tension and solution rheology measurements for the first time. It is evidenced that the surfactants have different effects on viscosity and surface tension, depending on their charge type. Micellization of the surfactant is affected by the presence of the polymer in all cases; shear viscosity of polymer solutions decreases in presence of the same charge or nonionic surfactants, while the opposite charge surfactant causes precipitation. This study highlights the importance of the charge type, and the role of the associating hydrophobic block in the PE structure, on the solution behavior of the mixtures. Moreover, a possible interaction model is proposed, based on the obtained data.

scholarly journals Self-Assembly of Microscale Parts through Magnetic and Capillary Interactions

Micromachines ◽  
2011 ◽  
Vol 2 (1) ◽  
pp. 69-81 ◽  
Author(s):  
Christopher J. Morris ◽  
Brian Isaacson ◽  
Michael D. Grapes ◽  
Madan Dubey
Keyword(s):  
Self Assembly ◽  
Capillary Interactions

scholarly journals Self-assembly of sodium dodecylsulfate and dodecyltrimethylammonium bromide mixed surfactants with dyes in aqueous mixtures

2019 ◽  
Vol 6 (3) ◽  
pp. 181979 ◽  
Author(s):  
K. M. Sachin ◽  
Sameer A. Karpe ◽  
Man Singh ◽  
Ajaya Bhattarai
Keyword(s):  
Surface Tension ◽  
Self Assembly ◽  
Sodium Dodecylsulfate ◽  
Critical Micellar Concentration ◽  
Aqueous System ◽  
Mixed Surfactants ◽  
Dodecyltrimethylammonium Bromide ◽  
Aqueous Mixtures ◽  
Krafft Temperature ◽  
Vis Spectroscopy

The micellar property of mixed surfactant systems, cationic (dodecyltrimethylammonium bromide, DTAB) and anionic (sodium dodecylsulfate, SDS) surfactants with variable molar ratios in aqueous system has been reported by using surface tension and conductivity measurements at T = 293.15, 298.15 and 303.15 K. DTAB concentrations are varied from 1.0 × 10 −4 to 3 × 10 −4 mol l −1 in 1.0 × 10 −2 mol l −1 SDS solution while the SDS concentration is varied from 1.0 × 10 −3 to 1.5 × 10 −2 mol l −1 in approximately 5.0 × 10 −3 mol l −1 DTAB, so that such concentrations of DTAB-SDS (DTAB-rich) and SDS-DTAB (SDS-rich) solutions were chosen 3 : 1 ratio. The critical micellar concentration, as well as surface and thermodynamic properties for DTAB-rich and SDS-rich solutions, were evaluated by the surface tension ( γ ) and conductivity ( κ ) methods. The pseudo phase separation model was coupled with the dissociated Margules model for synergism. The Krafft temperature behaviour and optical analysis of mixed surfactants are studied using conductivity and UV–Vis spectroscopy, respectively. The dispersibility and stability of DTAB-rich and SDS-rich solutions with and without dyes (2.5 × 10 −5 mol l −1 of methyl orange and methylene blue) are carried out by using UV–Vis spectroscopy and dynamic light scattering.

scholarly journals STM study on the self-assembly of oligothiophene-based organic semiconductors

2011 ◽  
Vol 2 ◽  
pp. 802-808 ◽  
Author(s):  
Elena Mena-Osteritz ◽  
Marta Urdanpilleta ◽  
Erwaa El-Hosseiny ◽  
Berndt Koslowski ◽  
Paul Ziemann ◽  
...  
Keyword(s):  
Organic Semiconductors ◽  
Self Assembly ◽  
Theoretical Calculations ◽  
The Self ◽  
Scanning Tunneling ◽  
Ambient Conditions ◽  
Tunneling Microscopy ◽  
Substitution Pattern ◽  
Electronic Density ◽  
The Individual

The self-assembly properties of a series of functionalized regioregular oligo(3-alkylthiophenes) were investigated by using scanning tunneling microscopy (STM) at the liquid–solid interface under ambient conditions. The characteristics of the 2-D crystals formed on the (0001) plane of highly ordered pyrolitic graphite (HOPG) strongly depend on the length of the π-conjugated oligomer backbone, on the functional groups attached to it, and on the alkyl substitution pattern on the individual thiophene units. Theoretical calculations were performed to analyze the geometry and electronic density of the molecular orbitals as well as to analyze the intermolecular interactions, in order to obtain models of the 2-D molecular ordering on the substrate.

scholarly journals The Contrasting Role of Water and Acid Within Organic Phase Amphiphile Aggregation

2021 ◽  
Author(s):  
Biswajit Sadhu ◽  
Aurora E. Clark
Keyword(s):  
Self Assembly ◽  
Dynamics Simulation ◽  
Test Bed ◽  
Network Analyses ◽  
Liquid Liquid Extraction ◽  
Polar Media ◽  
Polar Solutes ◽  
Local Aggregation ◽  
The Individual

Hypothesis: Amphiphile self-assembly in non-polar media is often enhanced by polar co-solutes, as observed upon amphiphile mediated transport of water and acid into organic solution. Such co-extraction precludes understanding the individual roles of polar solutes upon self-assembly. Using this liquid-liquid extraction (LLE) system as a test-bed, we hypothesize that co-solute competition and hydrogen bond (HB) characteristics cause different size/shape distributions of assembled amphiphiles and alter self-assembly mechanisms in non-polar solvents. Experiments: Concentration dependent classical molecular dynamics simulation and intermolecular network analyses identified the correlating relationships between HB properties of H2O and HNO3 upon the aggregation of N,N,N,N-tetraoctyl-3-oxapentanediamide (TODGA), a prevalent LLE amphiphile extractant. Findings: Concentration dependent competition of hydrogen bonding fundamentally impacts amphiphile self-assembly in non-polar media. H2O bridges TODGA and enhances self-assembly, however as [H2O]org increases, preferential self-solvation leads to large (H2O)n clusters that cause TODGA clusters to sorb to the (H2O)n periphery and form extended aggregation. HNO3 restricts the (H2O)n size by disrupting the HB network. At large [H2O]org, HNO3 modulates TODGA self-assembly from extended to local aggregation. We attribute prior experimental observations to the role of water rather than co-extracted HNO3, thus providing valuable new insight into the means by which extractant aggregation can be tuned.

scholarly journals Controlling the length of porphyrin supramolecular polymers via coupled equilibria and dilution-induced supramolecular polymerization

2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Elisabeth Weyandt ◽  
Luigi Leanza ◽  
Riccardo Capelli ◽  
Giovanni M. Pavan ◽  
Ghislaine Vantomme ◽  
...  
Keyword(s):  
Complex Systems ◽  
Self Assembly ◽  
Chiral Discrimination ◽  
Coarse Grained ◽  
Supramolecular Polymers ◽  
Supramolecular System ◽  
Precise Control ◽  
Aggregate Morphology ◽  
The Individual ◽  
Supramolecular Polymerization

AbstractMulti-component systems often display convoluted behavior, pathway complexity and coupled equilibria. In recent years, several ways to control complex systems by manipulating the subtle balances of interaction energies between the individual components have been explored and thereby shifting the equilibrium between different aggregate states. Here we show the enantioselective chain-capping and dilution-induced supramolecular polymerization with a Zn2+-porphyrin-based supramolecular system when going from long, highly cooperative supramolecular polymers to short, disordered aggregates by adding a monotopic Mn3+-porphyrin monomer. When mixing the zinc and manganese centered monomers, the Mn3+-porphyrins act as chain-cappers for Zn2+-porphyrin supramolecular polymers, effectively hindering growth of the copolymer and reducing the length. Upon dilution, the interaction between chain-capper and monomers weakens as the equilibria shift and long supramolecular polymers form again. This dynamic modulation of aggregate morphology and length is achieved through enantioselectivity in the aggregation pathways and concentration-sensitive equilibria. All-atom and coarse-grained molecular simulations provide further insights into the mixing of the species and their exchange dynamics. Our combined experimental and theoretical approach allows for precise control of molecular self-assembly and chiral discrimination in complex systems.

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