Kidney Injury in Children Infected with HIV, Followed at the Teaching Hospital of Borgou (Benin)

The history of kidney disease associated with HIV infection dates back to the years of HIV breakthrough. The objective was to study kidney damage in children infected with HIV at the Teaching Hospital of Borgou (Benin) in 2019. This was a cross-sectional, descriptive, analytical, matching-type study carried out from June 1, 2019 to September 30, 2019 at the pediatrics department of Teaching Hospital of Borgou (Benin). The study included HIV-positive children, followed in consultations, and whose parents gave their consent. The biological markers were demon-strated with urine dipstick. Glomerular filtration rate was calculated using the Schwartz test and classified according to stages. The dependent variable was the presence of at least one impairment (biological or functional). Sample size was determined by Schwartz’s method on the basis of one case for two controls. Sociodemographic, clinical, biological, and therapeutic data were collected. Comparisons were made using the Chi-square test or Fisher’s exact test. The identification of associated factors was possible using a multiple logistic regression model at 5% threshold. In total, we included 117 children, including 39 HIV-positive children. The average age was 8 ± 4.81 years and the gender ratio was 1:17. The frequency of kidney damage was 76.5%. Permanent proteinuria and at least two crosses on urine dipstick were present in 20.5%, leukocyturia in 2.6%, and proximal tubular dysfunction in 5.1%. Glomerular hyperfiltration was found in 38.5%, acute kidney injury in 38.5%, and chronic kidney injury in 5.1%. Associated factors were age (P = 0.004), presence of opportunistic infections (P = 0.00), and treatment adherence (P = 0.004). Kidney damage is common in HIV-positive children. Careful follow-up is necessary to avoid complications.

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Future Living Arrangement for Aging Parents and Its Associated Factors

Jurnal Keperawatan Soedirman ◽

10.20884/1.jks.2019.14.3.1196 ◽

2019 ◽

Vol 14 (3) ◽

Author(s):

Rahmi Setiyani ◽

Made Sumarwati ◽

Dian Ramawati

Keyword(s):

Older People ◽

Marital Status ◽

Associated Factors ◽

Living Arrangement ◽

Well Being ◽

Cross Sectional Study ◽

Family Type ◽

Fisher Exact Test ◽

Cross Sectional ◽

Exact Test

Background: Shift in demographic structure in Indonesia has raised concern over number of issues, including change in living arrangement of older people. Objectives: The purpose of this study is to examine adult children’s choice of future living arrangement for elderly parent and its associated factors. Methods: A cross sectional study was conducted among 300 young adults in Central Java, Indonesia. Descriptive statistics, Chi-Square and Fisher exact test were used to analyze the data. Results: Majority of respondents (97.3%) preferred parents to live at home, in multi-generational household with children and/or grandchildren (84.5%) in their old age. The choice was significantly influenced by children gender, marital status of parent, and family type (p=0.00; p=0.05, and p=0.05 respectively). Conclusions: In certain circumstances, living in multigenerational household still became a favorable option of living arrangement for elderly parents. Children gender, parent’s marital status and family type were likely to influence the choice. Further researches are needed to investigate which best living arrangement that support older people well-being.

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Opportunistic Infections and Associated Factors among HIV/AIDS Patients taking Ante-Retroviral Therapy at Selected Hospitals in Sidama Zone, Southern Ethiopia: A facility-based cross-sectional study

10.21203/rs.2.17125/v1 ◽

2019 ◽

Author(s):

Demelash Wachamo ◽

Fisseha Bonja

Keyword(s):

Associated Factors ◽

Opportunistic Infections ◽

Public Health Problem ◽

Cross Sectional Study ◽

High Morbidity ◽

Major Public Health Problem ◽

Sectional Study ◽

Aids Patients ◽

Cross Sectional ◽

Hiv Aids

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.

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PREVALENCE OF STRESS AND ITS ASSOCIATED FACTORS AMONG MEDICAL STUDENTS IN SABAH, MALAYSIA BORNEO

Malaysian Journal of Public Health Medicine ◽

10.37268/mjphm/vol.19/no.2/art.179 ◽

2019 ◽

Vol 19 (2) ◽

pp. 116-125 ◽

Cited By ~ 1

Author(s):

Aldrin Musiun ◽

Khamisah Awang Lukman ◽

Mohammad Saffree Jeffree ◽

Fredie Robinson ◽

Mohd Rohaizat Hassan ◽

...

Keyword(s):

Medical Education ◽

Medical Student ◽

Medical Students ◽

Associated Factors ◽

Health Care Services ◽

Cross Sectional Study ◽

Bivariate Analysis ◽

Chi Square ◽

Cross Sectional ◽

Exact Test

Stress is accepted as the accumulation of unpleasant state of physical, mental and emotion on a person. Medical education has been known as one of the most stressful academic curriculum. Hence, medical students may subjected to multiple psychological changes and challenges throughout the years of medical education. The aim of this study was to determine the prevalence of stress and its associated factors among medical students. This cross sectional study was conducted from April to May 2018 in medical school in Sabah. It involved 396 medical students through universal sampling. Self-administered questionnaires were used as an instrument for data collection. The questionnaires included were Sociodemographic Questionnaire, Depression, Anxiety and Stress Scales 21 (DASS-21) and Medical Student Stressors Questionnaire (MSSQ). Bivariate analysis (Chi Square test, Fisher’s Exact Test, Independent T test and Man-Whitney U test) were used to analyse the association. The response rate was 90.2%. The prevalence of stress among medical students were 33.3%. Significant associated factors include financial support inadequacy (p=0.010) and all categories of medical student stressors. The mean score of the academic related stressors was found to be at 2.117 (±0.758) which was the highest mean score among medical student stressors assessed by MSSQ. The result of this study can be used as a basis for implementation of preventive measures such as provision of comprehensive, integrated and responsive mental health care services in university-based settings.

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Management Outcome of Uterine Rupture and Associated Factors in Yirgalem General and Teaching Hospital, Southern Ethiopia: A Cross-Sectional Study

10.21203/rs.2.13383/v1 ◽

2019 ◽

Author(s):

Achamyelesh Tekle ◽

Hailemichael Hagos ◽

Kebede Tefera

Keyword(s):

Teaching Hospital ◽

Uterine Rupture ◽

Associated Factors ◽

Cross Sectional Study ◽

Southern Ethiopia ◽

Sectional Study ◽

Cross Sectional ◽

Prolonged Duration ◽

Poor Management

Abstract Background Uterine rupture is dropped significantly in the developed world. However, it is still a major public health problem in developing countries including Ethiopia. The aim of this study was to assess management outcome of uterine rupture and its associated factors in Yirgalem General and teaching Hospital of southern Ethiopia. Methods An institution based cross-sectional study was conducted. All records of uterine rupture managed in Yirgalem general and teaching hospital between January 1, 2012, and December 30, 2017, were reviewed. Data were collected using a checklist. Descriptive statistics and logistic regression analyses were done. Results A total of 331 cases of mothers who managed for uterine rupture were included in the study. 235 (71%) of them had a poor management outcome. Wound site infection 131 (39.6%) and anemia 129 (39%) where the common post-operative complications. There were 13 (4%) maternal death and 320 (96.7%) neonatal death. Lack of antenatal care follow up (adjusted odds ratio (AOR) =2.2, 95% CI: 1.1-4.5), prolonged duration of labor more than 24hr (AOR=3.6; 95% CI: 1.7-7.4), patients presented with sepsis (AOR=2.9; 95% CI: 1.4-6.1), mothers who did not transfuse for blood during the case scenario (AOR=4; 95% CI: 2.1-7.9) and prolonged intra operative time (AOR=5.5; 95% CI: 2.8-10.8) were factors associated with poor management outcome of uterine rupture. Conclusion Poor management outcome of uterine rupture was high in the study area as compared to other studies. Lack of ANC follow up, longer duration of the surgical procedure, prolonged duration of labor, lack of blood transfusion and pre and postoperative complications are associated with poor management outcome. Therefore, proper ANC and early identification of the high-risk groups can prevent and decline the occurrence of uterine rupture and that enhance good outcome.

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Self-medication among participants of an Open University of the Third Age and associated factors

Revista Brasileira de Geriatria e Gerontologia ◽

10.1590/1981-22562018021.170204 ◽

2018 ◽

Vol 21 (4) ◽

pp. 419-427

Author(s):

Adriana Nancy Medeiros dos Santos ◽

Dulcinéia Rebecca Cappelletti Nogueira ◽

Caroline Ribeiro de Borja-Oliveira

Keyword(s):

Associated Factors ◽

The Elderly ◽

Open University ◽

Self Medication ◽

Cross Sectional ◽

Third Age ◽

Exact Test ◽

The Third ◽

Chi Squared ◽

Articular Pain

Abstract Objective: to identify the prevalence of self-medication, the therapeutic classes used without medical prescription, the symptoms treated with such medication and associated factors among participants of an Open University of the Third Age (OU3A). Method: a cross-sectional, descriptive and analytical study was carried out, the sample of which was composed of 138 OU3A attendees. To estimate the association between the variables, prevalence ratios (PR), confidence intervals (95% CI), the chi-squared test and Fisher's exact test were used. Results: the majority were aged 60-69 years (61.6%), were female (75.4%), had a health plan (63%) and claimed to self-medicate (59.4%, 95% CI, 0-64.8). The most frequently mentioned therapeutic classes were analgesics (31.9%), muscle relaxants (13.8%), anti-inflammatories (13.0%) and first-generation antihistamines (7.2%). The most commonly reported self-medication symptoms were muscle and joint pain (21.0%), headaches (10.1%) and colds and flu (8.7%). There was a significant association (p = 0.049) among those who self-medicated more frequently and anti-inflammatory use (PR = 1.46, 95% CI = 1.10-1.99). The complaint of muscular and articular pain exhibited a significant association with the diagnosis of arthrosis (p = 0.003, RP = 3.75, 95% CI = 2.07-6.76) and hypothyroidism (p = 0.002, RP = 2.77 ; 95% CI = 1.50-5.10). Conclusion: the most frequently mentioned reasons for self-medicating were previous experience using the drug and the certainty that it is safe. Most of the above medications are potentially inappropriate for the elderly. However, the elderly consider them safe and are unaware of the risks to which they expose them. They may also be unaware that pain treated by self-medication may be related to pre-existing diseases, which require the appropriate professional and treatment.

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Comorbidity of HIV, hypertension, and diabetes and associated factors among people receiving antiretroviral therapy in Bahir Dar city, Ethiopia

Journal of Comorbidity ◽

10.1177/2235042x19899319 ◽

2020 ◽

Vol 10 ◽

pp. 2235042X1989931

Author(s):

Zenebework Getahun ◽

Muluken Azage ◽

Taye Abuhay ◽

Fantu Abebe

Keyword(s):

Antiretroviral Therapy ◽

Associated Factors ◽

Cross Sectional Study ◽

Noncommunicable Diseases ◽

Hiv Positive ◽

Bahir Dar ◽

Second Line ◽

Double Burden ◽

Cross Sectional ◽

Hiv Positive Adults

Background: People living with human immunodeficiency virus (HIV) are facing an increased burden of noncommunicable diseases (NCDs) comorbidity. There is, however, paucity of information on the magnitude of HIV-NCDs comorbidity, its associated factors, and how the health system is responding to the double burden in Ethiopia. Objective: To determine the magnitude of comorbidity between HIV and hypertension or diabetes and associated factors among HIV-positive adults receiving antiretroviral therapy (ART) in Bahir Dar city, Ethiopia. Methods: A facility-based cross-sectional study was conducted among 560 randomly selected HIV-positive adults taking ART. Data were collected using a structured questionnaire and analyzed using SPSS version 23. Descriptive statistics were used to describe the data. A logistic regression model was fit to identify associated factors with comorbidity of HIV and NCDs. Results: The magnitude of comorbidity was 19.6% (95% confidence interval (CI): 16.0–23.0). Being older (55 and above years) adjusted odds ratio (AOR: 8.5; 95% CI: 3.2–15.1), taking second-line ART regimen containing tenofovir (AOR: 2.7; 95% CI: 1.3–5.6), and increased body mass index (BMI) ≥25 (AOR: 2.7; 95% CI: 1.2–6.5) were the factors associated with comorbidity. Participants reported that they were not managed in an integrated and coordinated manner. Conclusions: The magnitude of comorbidity among adults was high in the study area. Being older, second-line ART regimen and high BMI ≥25 increased the odds of having NCDs among HIV-positive adults. Targeted screening for the incidences of NCDs, addressing modifiable risk factors, and providing integrated care would help to improve the quality of life comorbid patients.

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Prevalence of neurocognitive impairment and its associated factors among patients with HIV in Indonesia

British Journal of Neuroscience Nursing ◽

10.12968/bjnn.2020.16.6.258 ◽

2020 ◽

Vol 16 (6) ◽

pp. 258-264

Author(s):

Linlin Lindayani ◽

Diwa Agus Sudrajat ◽

Chanti Melnawati ◽

Dian Anggarini

Keyword(s):

Cognitive Impairment ◽

Associated Factors ◽

High School Graduates ◽

Cross Sectional Study ◽

Neurocognitive Impairment ◽

Hiv Positive ◽

Study Participation ◽

Cross Sectional ◽

The Mean ◽

Living With Hiv

Background: Patients with HIV are susceptable to developing HIV-associated neurocognitive disorder (HAND). However, few studies have explored the prevalence of neurocognitive impairment and its associated factors among patients with HIV in Indonesia. Aims: This study aimed to explore the prevalence of neurocognitive impairment in patients with HIV in Indonesia. Methods: A cross-sectional study was conducted among patients with HIV in West Java, Indonesia. Patients were eligible for study participation if they were HIV-positive and were aged over 20 years. The International HIV Dementia Scale (IHDS) was used to measure probable HIV–related dementia. Descriptive categorisations and statistics, using mean scores, standard deviation (SD) calculations or frequency rates, were applied to participant characteristics and major variables. Findings: There were a total 150 participants in this study. The mean age was 38.09 years (SD=3.99); 74% were male; 80.7% were high school graduates. The mean of CD4 counts was 493.3 (SD=139.8), and all participants had been living with HIV for more than 9 years (SD=3.84). The mean of total scores using the IHDS was 10.2 (SD=1.58), and 49.30% of patients with HIV were reported to have cognitive impairment. There was an increased prevalence of cognitive impairment among males with a higher BMI and higher systolic blood pressure Conclusions: Nearly half of patients with HIV in Indonesia are at high risk of cognitive impairment, as measured by IHSD. Health professionals caring for patients with HIV may consider routine neurocognitive impairment screenings during clinical visits to address this risk.

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Prevalence and Associated Factors of Tuberculosis in Prisons Settings of East Gojjam Zone, Northwest Ethiopia

International Journal of Bacteriology ◽

10.1155/2017/3826980 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Mucheye Gizachew Beza ◽

Emirie Hunegnaw ◽

Moges Tiruneh

Keyword(s):

Associated Factors ◽

Public Health Problem ◽

Cross Sectional Study ◽

Northwest Ethiopia ◽

Hiv Positive ◽

Major Public Health Problem ◽

Cross Sectional ◽

Hiv Coinfection ◽

Rural Dwellers ◽

Prison Admission

Background. Tuberculosis, mainly in prisoners, is a major public health problem in Ethiopia where there is no medical screening during prison admission. This creates scarcity of TB data in such settings. Objective. To determine prevalence and associated factors of TB in prisons in East Gojjam Zone, Northwest Ethiopia. Methods. A cross-sectional study was conducted from February to May 2016 among 265 prisoners in three prison sites. Sputum was processed using GeneXpert MTB/RIF. Data were analyzed using SPSS version 20.0. Multivariable logistic regression was used; p values = 0.05 were considered statistically significant. Results. Of 265 prisoners, 9 (3.4%) were TB positive (males); 77.8%, 55.6%, and 55.6% of cases were rural dwellers, married, and farmers, respectively. Seven (2.6%) prisoners were HIV positive, and 3 (1.13%) had TB/HIV coinfection. One (0.4%) TB case was rifampicin resistant. Marriage (AOR = 1.5; 95% CI: 1.7, 13.03), HIV (AOR = 0.14; 95% CI: 0.001, 0.17), and sharing of rooms (AOR = 1.62; 95% CI: 2.6, 10.20) were predictors for TB. Conclusion. Nine prisoners were TB positive. One case showed rifampicin resistance and three had TB/HIV coinfection. Marriage, HIV, and sharing of rooms were predictors for TB. Prevention/control and monitoring are mandatory in such settings.

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Nonadherence to Self-Care Practices, Antihypertensive Medications, and Associated Factors among Hypertensive Patients in a Follow-up Clinic at Asella Referral and Teaching Hospital, Ethiopia: A Cross-Sectional Study

International Journal of Hypertension ◽

10.1155/2021/7359318 ◽

2021 ◽

Vol 2021 ◽

pp. 1-10

Author(s):

Addisu Dabi Wake ◽

Techane Sisay Tuji ◽

Addisu Tadesse Sime ◽

Mekuria Tesfaye Mekonnin ◽

Taju Mohamed Taji ◽

...

Keyword(s):

Teaching Hospital ◽

Associated Factors ◽

Formal Education ◽

Self Care ◽

Multivariable Logistic Regression Analysis ◽

Antihypertensive Medications ◽

Cross Sectional ◽

Hypertensive Patients ◽

Care Practices

Background. Hypertension is one of the most common noncommunicable diseases affecting several individuals globally. However, the level of nonadherence to self-care practices, antihypertensive medications, and associated factors among hypertensive patients in a follow-up clinic at Asella Referral and Teaching Hospital is unknown. Objective. To assess the level of nonadherence to self-care practices, antihypertensive medications, and associated factors among hypertensive patients in a follow-up clinic at Asella Referral and Teaching Hospital, Arsi Zone, Oromia Regional State, Ethiopia, in 2020. Methods. An institution-based cross-sectional survey was conducted on 115 hypertensive patients who visited the follow-up clinic at Asella Referral and Teaching Hospital from December 24, 2020, to January 15, 2021. Data were entered into EpiData version 4.2.0.0 and exported to SPSS version 21.0 for statistical analysis. Binary and multivariable logistic regression analysis was used to assess the presence of statistical association between dependent and independent variables. Results. A total of 115 hypertensive patients were enrolled into the study, giving a response rate of 98.29%. The mean age of the study participants was 55.17 years (SD = 17.986). More than half of them (59 (51.3%)) were females. More than half of them (58 (50.4%)) were married. Nearly two-thirds of them (79 (68.7%)) had formal education. The level of nonadherence to self-care practices was 67.0% (n = 77, 95% CI: 60.0, 75.7). Meanwhile, the patient’s level of nonadherence to antihypertensive medications was 16.5% (n = 19, 95% CI: 10.4, 24.3). The multivariable logistic regression analysis showed that age >45 years (AOR = 2.89, 95% CI: 1.16, 7.18), having no formal education (AOR = 1.67, 95% CI: 1.32, 3.74), and having ≤5 years’ duration since diagnoses of hypertension (AOR = 1.56, 95% CI: 1.07, 3.25) were factors significantly associated with nonadherence to self-care practices. Being male (AOR = 2.09, 95% CI: 1.93, 9.59), being married (AOR = 4.22, 95% CI: 1.29, 13.76), and having an average monthly income of ≤2500 ETB (AOR = 1.58, 95% CI: 1.09, 7.08) were factors significantly associated with nonadherence to medications. Conclusion. In the present study, the level of both nonadherence to self-care practices and antihypertensive medications was relatively high. There is a need to initiate programs that could create awareness about adherence to self-care practices and antihypertensive medications among hypertensive patients to improve their level of adherence.

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