Comparative Evaluation of Bioactive Glass (Putty) and Platelet Rich Fibrin in Treating Furcation Defects

2016 ◽  
Vol 42 (5) ◽  
pp. 411-415 ◽  
Author(s):  
Shriparna Biswas ◽  
Savita Sambashivaiah ◽  
Rithesh Kulal ◽  
Shivaprasad Bilichodmath ◽  
Gregori M Kurtzman

The aim of this study was to compare a second-generation bioactive glass putty biomaterial against platelet rich fibrin in treating grade II furcation defects. Subjects were 15 systemically healthy patients (10 males and 5 females, ages 20–50 with a mean age of 38.33) with 20 mandibular molar class II furcation defects according to Glickman's classification. The 20 mandibular molar furcation defects were randomly allocated as follows: Group I, 10 furcation defects were treated using bioactive glass (NovaBone) bone graft putty material; Group II, 10 furcation defects were treated using platelet rich fibrin (PRF). Customized acrylic stents were fabricated on study casts and trimmed to the height contour of the teeth to serve as a fixed reference point for measurements. The following measurements were collected: gingival index, plaque index, vertical probing depth (from gingival margin to base of the pocket), clinical attachment level (CEJ to the base of the pocket), and horizontal probing depth of furcation involvement (using stent). Results showed that both groups had improvement in gingival index (GI) and plaque index (PI) at the recall intervals. There was an overall reduction in both vertical and horizontal probing depth in both groups; however, the Putty group (Group I) showed consistently more vertical probing depth reduction than the PRF group (Group II) at the end of third month (P-value = 0.0004), sixth month (P-value = 0.00001), and ninth month (P-value = 0.0004). Our conclusion was that use of bioactive glass osteostimulative biomaterial yields superior clinical results, including increased pocket depth reduction of class II furcation defects as compared to an autologous platelet concentrate. The clinical significance of our findings include the ease of use and superior biologic performance of second-generation putty bioglass biomaterials in furcation defects.

2016 ◽  
Vol 17 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Vineet Kini ◽  
Dilip G Nayak ◽  
Ashita S Uppoor

ABSTRACT Background Guided tissue regeneration (GTR) therapy has shown good results in the management of mandibular molar class II furcation defects. Advances in biomaterial sciences have developed alloplastic bone replacement graft materials and bioabsorbable GTR barrier membranes with good biologic response and handling properties. The aim of this study was to compare the attachment gain and the bone fill obtained with an alloplast [biphasic calcium phosphate (BCP) 60% hydroxyapatite (HA) and 40% beta tricalcium phosphate (β-TCP)] with and without a bioabsorbable GTR barrier [flowable poly (DL-lactide) (PLA) dissolved in N-methyl-2- pyrrolidone (NMP)] in the treatment of mandibular molar class II furcation defects. Materials and methods A total of 20 class II furcation defects were treated in 16 patients with chronic periodontitis in a comparative study. Ten defects were treated with Camceram® (BCP 60% HA and 40% – TCP) bone replacement graft material (group I) and 10 defects with a combination of Camceram® bone replacement graft material with Atrisorb® Freeflow™, bio-absorbable GTR barrier (flowable PLA dissolved in NMP) (group II). At baseline and at 6 months postsurgery, clinical parameters of vertical probing depth (PD) and horizontal probing depth (P-H), clinical attachment level (CAL), gingival recession (GR), and vertical depth of furcation defect (VDF) and horizontal depth of furcation defect (BP-H) were evaluated. Results Statistical analysis was done with the Statistical Package for Social Sciences (SPSS) program. Intergroup comparisons made at 6 months postsurgery by unpaired Student's t-test showed mean reduction in PD in group I was 3.10 ± 0.73 mm and in group II was 3.20 ± 1.03 mm (p > 0.05). Mean reduction in P-H in group I was 1.60 ± 0.69 mm and in group II was 1.90 ± 0.73 mm (p > 0.05). Gain in CAL in group I was 2.80 ± 1.03 mm and in group II was 2.90 ± 0.94 mm (p > 0.05). Change in GR in group I was .0.30 ± 0.48 mm and in group II was .0.30 ± 0.48 (p > 0.05). Reduction in VDF in group I was 1.30 ± 0.67 mm and in group II was 1.80 ± 0.63 mm (p . 0.01). Reduction in BP-H in group I was 1.30 ± 0.67 mm and in group II was 1.90 ± 0.73 mm (p . 0.05). Conclusion It was concluded that the combination technique of BCP alloplast with a flowable bioabsorbable GTR barrier led to better results in regard to defect bone fill as compared with when the BCP alloplast alone was used. How to cite this article Kini V, Nayak DG, Uppoor AS. A Clinical Evaluation of Biphasic Calcium Phosphate Alloplast with and without a Flowable Bioabsorbable Guided Tissue Regeneration Barrier in the Treatment of Mandibular Molar Class II Furcation Defects. J Contemp Dent Pract 2016;17(2):143-148.


2021 ◽  
Vol 9 (D) ◽  
pp. 170-178
Author(s):  
Ragia Saad Mohamed Kotb ◽  
Ahmed Gamal Ahmed Hassan ◽  
Emad Mohamed Tolba M. Agamy ◽  
Gehan Fekry Mohamed

Objective: To evaluate and compare the effect of implant supported versus implant retained removable partial denture restoring Kennedy's class I cases on the supporting structures by measuring modified gingival index and probing depth for abutment teeth and implants. Subjects and Methods: Twelve patients; who had Kennedy class I mandibular partially edentulous ridge extending distal to the first or second premolar,   were selected from the outpatient clinic, Prosthodontics Department, Faculty of Dentistry, Minia University. The patients were classified into two equal groups; according to the implant superstructures either dome shaped abutment or ball and socket attachment.  Each Patient of both groups had two implants in second molar position (one in each side) and received removable partial denture of the same design. Patients were followed up for one year clinically. Group I: Six patients received RPD supported by dome shaped short abutments.  Group II six patients received RPD retained by ball and socket attachments. Results: Results revealed that, there was no statistically significant difference between the two groups regarding modified gingival index and probing depth around the abutment teeth and implant abutment. Conclusion:  The use of dome shaped abutment or ball and O-ring attachment have the same effect on gingival index and probing depth around natural abutments and implants in Kennedy class I mandibular situations.


Author(s):  
Anant Raghav Sharma ◽  
Spoorti Pattanashetty ◽  
Pradnya Wagh Kamat ◽  
Ramisetty Sabitha ◽  
Nidhi Chhaparia

Background: In periodontal therapy, furcation defects are one of the most therapeutically challenging periodontal therapies. Till now various treatment methods have been tried which have shown different success rates. The present study was undertaken to compare the efficacy of bioactive glass (alloplast) with Freeze dried bone allograft (FDBA) in the treatment of Class II furcation defects. Materials and Methods: Twenty patients were selected for the study which had bilateral Class II furcation defects in molars from which ten patients were male and ten patients sere female in the age group of 45-55 years. Various clinical measurements were recorded at three times i.e. at baseline, at one month and at six months post surgery which included the Turesky-Glimore-Glickman modification of the Quigley Hein plaque index, the Loe and silness gingival index, relative clinical attachment level vertical probing depth in the mid-furcation area, and horizontal probing depth in the furcation area. The statistical analysis was done using SPSS version 23.0. Results: In the relative clinical attachment levels, the mean gain in the test and control groups was 2.45 and 1.58 mm, respectively at the end of six months. In the horizontal probing depth values, the mean change in the bioactive glass graft and freeze dried bone allograft was 1.45 and 1.33 mm, respectively. Conclusion: From our study it was concluded that efficacy of Bioactive glass is much better as compared to Freeze dried bone allograft in the treatment of Class II furcation defects. Keywords: Bioactive glass, Freeze dried bone allograft, furcation defects


2004 ◽  
Vol 18 (2) ◽  
pp. 121-127 ◽  
Author(s):  
Solange Alonso Vergani ◽  
Emílio Barbosa e Silva ◽  
Adriana Helena Vinholis ◽  
Rosemary Adriana Chiérici Marcantonio

The aim of the present parallel, double-blind investigation was to evaluate the effect of using systemic metronidazole alone or associated to scaling and root planing on adult chronic periodontal disease, monitored at baseline, 30, 60 and 90 days. Twelve subjects were divided into three groups: the first group (Group I - 22 sites) was submitted to scaling and root planing (SRP) alone; the second group (Group II - 30 sites) received SRP and 250 mg of metronidazole (3 times a day for 10 days), and the third group (Group III - 31 sites) was treated with metronidazole alone. The clinical parameters evaluated were probing depth (PD), clinical attachment level (CAL), plaque index (PlI), gingival index (GI) and bleeding upon probing (BP). Microbiological (BANA test) and enzymatic (Pocket Watch) tests were also performed. All three proposed treatments produced significant improvements in clinical conditions of subjects, from baseline, 30, 60 and 90-day period, except for clinical attachment level. The results obtained by microbiological and enzymatic tests did not show statistical differences among the groups for the 90-day period (r = 0.7924 and r = 0.7757, respectively). In relation to clinical parameters, statistical differences among groups were observed only for the gingival index (p = 0.0261) between Groups I and II, and probing depth (p = 0.0124) between Group I and the others. We conclude that the use of systemic metronidazole did not produce additional effects on the microbiological conditions of these patients with chronic periodontal disease.


Author(s):  
Shaili Pradhan ◽  
Benju Shrestha

Introduction: Attached gingiva aids in increased resistance to external injury and contribute in stabilisation of gingival margin against frictional forces as well as dissipates physiological forces exerted by the muscular fibers of the alveolar mucosa on gingival tissues. Objective: To assess width of attached gingiva in adults and correlate with oral hygiene maintenance and gingival inflammation. Methods: A cross-sectional study was conducted in patients aged 20-40 years visiting dental OPD with healthy periodontium. Plaque index (PI) and Gingival index (GI) were recorded. Mucogingival junction was determined by visual and functional method. Keratinised gingiva width (KGW) and probing pocket depth (PPD) was recorded and attached gingiva width (AGW) was calculated as (KGW–PPD). Results: Total 85 patients (43 males and 42 females) enrolled in this study. Among total, 48.23% had AGW<1 mm. AGW <1 mm most commonly was found in mandibular first premolar, highest mean AGW was found in maxillary incisors. The mean GI and PI values for AGW<1 mm were found to be higher than those for AGW≥ 1 mm. However, result did not show any significant relation between AGW and severity of gingival inflammation (P value 0.608) and plaque control (P value 0.297). Conclusion: The correlation between attached gingiva width and severity of gingival inflammation and plaque index was not significant statistically. However, the mean gingival index and plaque index score were higher for the attached gingiva width less than 1 mm.


2021 ◽  
Vol 13 (4) ◽  
pp. 135-141
Author(s):  
Mohsen Bidgoli ◽  
Maryam Pourjebreil

Background: Many patients refer to their load implants while there is no attached gingiva in the area of prosthetic implants – unlike the attached gingivae found with natural teeth. The important role played by gingiva in comforting the patient and preventing gingival inflammation has not been fully appreciated yet. This study aimed to evaluate the association between the attached gingival height with gingival inflammation and patients’ comfort. Methods: This retrospective cohort study was conducted to examine 80 implants (Dio uf) placed in 63 patients. At least two months had passed since the patients had had implant crown. The patients were divided into three groups: attached gingiva, gingival up to 2 mm, and at least 2 mm of attached gingiva. Indices such as bleeding on probing (BOP), the amount of plaque, gingival index and patient comfort during brushing and chewing were evaluated. Statistical data were analyzed using the Kolmogorov– Smirnov test, Levene’s test and independent t-test. Results: By increasing the height of attached gingiva, decreases were observed in probing depth (P value=0.004), BOP (P value=0.001), the degree of plaque index (P value=0.006), and gingival index (P value=0.003); and this association was statistically quite significant. By increasing the attached gingiva height, furthermore, the patients felt less discomfort when brushing and chewing; however, the findings were not statistically significant in terms of patients’ comfort during chewing (P value=0.364). Conclusions: Increasing the height of attached gingiva reduced the symptoms of gingival inflammation, but increased patients’ comfort when chewing and brushing.


Author(s):  
Archie Khera ◽  
Arvind Shenoy

Introduction: Composite resins are currently the most popular restorative materials due to their superior esthetics, strong mechanical properties and high resistance to dissolution. However, in spite of the improvements in resin composite formulations over the years, polymerisation shrinkage which necessitates incremental placement techniques still presents clinical challenges. Aim: To compare and evaluate cavosurface marginal integrity in Class I restorations by assessing microleakage scores using Tetric N-Flow Bulk fill, SureFil Bulk fill composites and Filtek Z350 XT and using selective etch and self etch modes of a universal adhesive. Materials and Methods: This in-vitro research study was carried out in the Department of Conservative Dentistry and Endodontics, Bapuji Dental College and Hospital, Davangere, Karnataka, India from April, 2018 to May, 2018. Sixty extracted non-carious, intact human mandibular molar teeth were selected for this study. Standardised Class I cavities of 4 mm depth were prepared by a single operator with a high-speed hand piece using carbide fissure # 245 (SS White Inc) bur under air-water coolant. Samples were randomly divided into two main groups in which Single Bond Universal was used: Group I: Selective Etch Mode (30), Group II: Self Etch Mode (30). These main groups were then divided into 3 subgroups each Subgroup TF: Tetric N- Flow Bulk fill (Ivoclar Vivadent), Subgroup SB: SureFil Bulk fill (Dentsply) and Subgroup FC: Filtek Z350 XT (3M ESPE). All the specimens were then sectioned longitudinally along the mesio-distal direction towards the center of the restoration. Each specimen was viewed under a stereomicroscope and grading was done according to dye penetration at the tooth-restoration interface. Kruskal-Wallis and Mann-Whitney U-test were used to analyse the results. Results: The results showed that there was statistically significant difference in the microleakage scores of Tetric N- Flow Bulk fill, Filtek Z350 XT and SureFil Bulk fill (p<0.001). Group I Subgroup TF yielded lower microleakage score 0.70±0.675 as compared to Group II Subgroup TF which had a higher score 1.60±1.578. This difference was not statistically significant. (p-value=0.266). Group I Subgroup SB yielded lower microleakage score 1.20±0.919 as compared to Group II Subgroup SB which had a higher score 2.10±0.568. This difference was statistically significant. (p-value=0.017). Group I Subgroup FC yielded lower microleakage score 2.50±1.354 as compared to Group II Subgroup FC which had a higher score 3.20±0.789. This difference was not statistically significant (p-value=0.260). Conclusion: Tetric N flow bulk fill flowable composite resin can be considered as a better choice when compared to SureFil bulk fill and Filtek Z350XT composite resins. Selective enamel etching with SureFil bulk fill should be considered as the better choice as compared to self-etch for providing adequate seal in mild universal adhesives in Class I cavities.


Author(s):  
Shilu Shrestha ◽  
Surendra Man Shrestha ◽  
Ameena Pradhan ◽  
Shreeya Aryal

Background: Porous hydroxyapatite and β-tricalcium phosphate (β-TCP + HA) bone grafting material has resulted in clinically acceptable responses when used to fill the periodontal intrabony defects. PRF is an autologous leukocyte and platelet preparation that concentrates various polypeptide growth factors which therefore holds potential to be used as regenerative treatment for periodontal defects. Aim: The purpose of this study was to evaluate clinical and radiographic outcomes in periodontal intrabony defects treated with platelet rich fibrin compared to alloplastic bone graft material. Materials and Methods: Twenty subjects (10 subject per group, one site/subject) were treated either with platelet rich fibrin or alloplastic bone graft (30% β-TCP+ 70% HA). Primary clinical parameters: PD, CAL were taken at baseline, three months, six months and nine months post-operatively. Standardised radiographic data were collected at baseline, six months and nine months postoperatively. Results: Preoperative parameters were similar for both groups. Postsurgical measurements revealed a greater reduction in pocket depth in bone graft group (2.5 mm), greater CAL gain (2.2 mm) and greater defect fill (1.30 mm) as compared to platelet rich fibrin group (1.50 mm, 1.6 mm and 0.80 mm respectively ) at nine months. Conclusion: Treatment of intrabony defects with alloplast (30% β TCP+ 70% HA) or platelet rich fibrin both resulted in a significant probing depth reduction, CAL gain and bone depth reduction, with significantly better improvement in bone graft group.


2019 ◽  
Vol 13 (1) ◽  
pp. 478-487 ◽  
Author(s):  
Fathima F. Farook ◽  
Ka Ting Ng ◽  
Nuzaim MNM ◽  
Wen J. Koh ◽  
Wan Y. Teoh

Introduction: Several articles have suggested a potential synergistic relationship between periodontal disease and systemic inflammatory diseases, such as Polycystic Ovarian Syndrome (PCOS) and diabetes mellitus. However, the associations between periodontal disease and PCOS population remain unclear in the literature. Objective: The primary aim of this review is to examine the associations between periodontal disease and PCOS with different scoring methods, namely clinical attachment loss, probing depth, gingival index, percentage of bleeding on probing and plaque index. Methods: MEDLINE, EMBASE and CENTRAL were systematically searched for observational studies and case-control studies from its inception until 2nd June, 2019. Case reports, case series, non-systematic reviews and trials published as abstracts were excluded. Results: Four articles (614 subjects) were included for analysis. Out of 614 subjects, 329 PCOS patients were compared to 285 healthy subjects. In comparison to healthy cohort, women with PCOS had a statistically significant increase in clinical attachment loss (MD: 0.34, 95% CI: 0.13-0.55, ρ=0.002), probing depth (MD: 0.35, 95%CI: 0.21-0.48, ρ<0.001), gingival index (MD: 0.70, 95% CI: 0.70-1.11, ρ<0.001) and percentage of bleeding on probing (MD: 34.41, 95% CI: 20.23-48.59, ρ<0.001). No difference was demonstrated in plaque index (MD: 0.42, 95% CI: -0.29-1.12, ρ=0.24) for both PCOS and healthy cohort. Conclusion: PCOS is significantly associated with a higher severity of the periodontal disease. This association should be emphasized during the management of PCOS patients, by including referral to dentists or periodontists for regular mechanical debridement of plaque and periodontal maintenance.


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