scholarly journals Determination of Antibiotic Residues: I. Extraction and Clean-up Methods for Solid Samples_A Review

2016 ◽  
Vol 32 (6) ◽  
pp. 600-627
Author(s):  
Chansik Kim ◽  
Hong-Duck Ryu ◽  
Eu Gene Chung ◽  
Yongseok Kim ◽  
Doug Hee Rhew
Keyword(s):  
2008 ◽  
Vol 71 (1) ◽  
pp. 223-225 ◽  
Author(s):  
IXCHEL REYES-HERRERA ◽  
DAN J. DONOGHUE

Use of antibiotics by the poultry industry has the potential to produce residues in edible tissues. In order to protect consumers, the U.S. federal government performs extensive evaluations to quantify residues in edible tissues to ensure that concentrations do not exceed the tolerance level. However, in the case of muscle tissue, the regulatory process does not differentiate between different edible muscle types in poultry. Previous studies performed by our laboratory determined higher fluoroquinolone residue concentrations in breast versus thigh muscle. Thus, if thigh tissues were used for residue monitoring, it would not accurately depict the higher concentrations. It is also possible that residue concentrations vary within tissues. To evaluate this possibility, fluoroquinolone antibiotic residues were determined for different breast sections. One hundred sixty chickens were randomly divided into four groups and dosed at 33 days of age with the fluoroquinolone antibiotic, enrofloxacin (Baytril), at either 25 ppm for 3 days, 25 ppm for 7 days, 50 ppm for 3 days, or 50 ppm for 7 days. Breast fillets were collected from each bird (n = 5 birds per day per group) during the dosing and withdrawal period. Each breast was divided into four sections (upper left, upper right, lower left, and lower right) that were analyzed as individual samples for determination of fluoroquinolone concentration. Our results indicated no significant difference (P > 0.05) in the levels of enrofloxacin residues between breast sections during the dosing or withdrawal periods. Consequently, samples can be collected from any breast section to evaluate fluoroquinolone residue concentrations during the regulatory monitoring process.


1981 ◽  
Vol 44 (3) ◽  
pp. 194-200 ◽  
Author(s):  
M. BIELECKA ◽  
J. D. BALDOCK ◽  
A. W. KOTULA

Ten parameters affecting sensitivity, accuracy and simplicity of the diffusion plate method for determining antibiotic residues in meat were evaluated with spores of Bacillus stearothermophilus as the test organism. Eight antibiotics were studied and included penicillin, bacitracin, tetracycline, chlortetracycline, oxytetracycline, streptomycin, erythromycin and neomycin. Sensitivity of the method was most influenced by concentration of inoculum, quantity of assay medium on the plate and sample size. The optimal concentration of inoculum was established as 2 × 105 spores/ml of medium, quantity of the assay medium on plate/100 mm dia., as 6 ml and quantity of sample poured on disc/12.7 mm dia., as 100 μl. The pH of the assay medium was also important to both antibiotic potency and test organism growth. The activity of streptomycin and erythromycin was the most sensitive to pH variations.


2019 ◽  
Vol 411 (23) ◽  
pp. 6129-6139 ◽  
Author(s):  
Beatriz Albero ◽  
José Luis Tadeo ◽  
Esther Miguel ◽  
Rosa Ana Pérez

2019 ◽  
Vol 59 (1) ◽  
pp. 25-34
Author(s):  
Atul Kumar ◽  
Jatinder Paul Singh Gill ◽  
Jasbir Singh Bedi ◽  
Pardeep Kumar Chhuneja ◽  
Amit Kumar

2018 ◽  
Vol 25 (2) ◽  
pp. 163 ◽  
Author(s):  
A. Ibrahim Ghada ◽  
A. Nour Ikhlas ◽  
Al-Maqbali Rabea ◽  
I.T. Kadim

2003 ◽  
Vol 31 (1) ◽  
pp. 36-44 ◽  
Author(s):  
Thorsten Christian ◽  
Rudolf J. Schneider ◽  
Harald A. Färber ◽  
Dirk Skutlarek ◽  
Michael T. Meyer ◽  
...  

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