scholarly journals Age-specific Epidemiology of the Antibody Response Prevalence in Children with Food Allergy

2016 ◽  
Vol 71 (1) ◽  
pp. 68-76
Author(s):  
M. A. Snovskaya ◽  
L. S. Namazova-Baranova ◽  
E. L. Semikina ◽  
S. G. Makarova ◽  
O. V. Kozhevnikova ◽  
...  

Food allergy (FA) is an important health problem which determines lower life quality of a patient and his family. Egg proteins, milk, soy, wheat, and nuts provoke FA more often but any food product may potentially cause allergic reactions. So the aim was to study the age-specific dynamics of antibody response and select the most meaningful IgE production triggers in children with PA. Materials and Methods. The study included 682 children with FA divided into groups according to age: 2−5 months, 6−18 months, 1.5−4 years, 4−10 years, older than 10 years. The IgE levels to cereals, vegetables, bananas, meat, and poultry allergens were measured in blood samples. Results. The age dynamic of IgE-positive responses was detected. The frequency of positive responses was higher in older children. The most significant IgE production triggers for 2−5 months children were allergens of potatoes, pork and cereals (8−14%); for 6−18 month children potatoes (22.7%), buckwheat (19,3%), cereals (10−15%); for 1.5−4 years children ― bananas (29.5%), cereals, carrots and potatoes (19,5−24%); for 4−10 years children ― bananas, carrots and cereals (20−28%); for the senior children ― carrots (47.5%), bananas, cereals and tomatoes (30−36%). Chicken-specific IgE-positive response was minimal for all ages, and meat or poultry specific IgE were observed in 8−15% of patients. Conclusion. Different groups of food allergens provoke sensitization in children during their life. The range of food products with low allergenic activity remains constant in various ages. Age characteristics of IgE production requires differentiated diagnosis approach. 

Author(s):  
Eko Handoyo ◽  
Nur Ranika Widyaningrum

Keberadaan PKL di sepanjang jalan raya Magelang-Yogyakarta km 5-8 menyebabkan terganggunya kelancaran, ketertiban, keindahan dan kebersihan jalan. Untuk menyelesaikan permasalahan tersebut, pemerintah Kabupaten Magelang merelokasi PKL di sepanjang jalan raya Magelang-Yogyakarta km 5-8 ke PKL Mertoyudan Corner. Tujuan penelitian ini adalah untuk menganalisis bagaimana respons, kesejahteraan, dan kualitas hidup PKL pasca relokasi untuk melihat praktik pemberdayaan yang efektif. Penelitian ini menggunakan metode kualitatif. Hasil penelitian dianalisis dengan teknik analisis kualitatif. Hasil penelitian menunjukkan bahwan PKL di jalan raya Magelang-Yogyakarta km 5-8 sebagian besar menunjukkan respons yang positif terhadap kebijakan relokasi, yaitu dalam bentuk penerimaan dan persetujuan (40% di antaranya memutuskan pindah). Kesejahteraan PKL, terutama dilihat dari pendapatan mengalami penurunan. Kualitas hidup PKL yang diukur dari aspek penghasilan, pemenuhan kebutuhan material, derajat dipenuhinya kebutuhan hayati, kebutuhan manusiawi dan kebebasan memilih juga menunjukkan penurunan. Kesimpulannya relokasi sebagai pemberdayaan agar berfungsi dengan baik harus mengembangkan program-program kreatif untuk mempopulerkan tempat relokasi.The presence of street vendors along Highway Magelang-Yogyakarta KM 5-8 lead to the disruption of the smooth, order, beauty and cleanliness of the streets. To resolve these problems, the government relocate the street vendors to street vendors Mertoyudan Corner. The purpose of this study was to analyze how the response, quality of life, and well-being after relocation to illuminate the practice of effective of empowerment. This study used qualitative methods. results showed that street vendors in Magelang-Yogyakarta highway km 5-8 mostly show a positive response to the relocation policy, namely in the form of acceptance and approval, while 40% of them decide to move. The welfare of street vendors, expecially seen from the revenue decline and the quality of life as measured from the street vendors prosperous income aspect, the fulfillment of material needs, the degree of fulfillment of biological needs, human needs and freedom of choice also showed a decline. The study concludes that to function properly, relocation as empowerment should develop creative programs to develop the relocation sites.


2020 ◽  
Author(s):  
Natasha Correa ◽  
Jennifer LP Protudjer ◽  
Elaine Hsu ◽  
Lianne Soller ◽  
Edmond S Chan ◽  
...  

Abstract Background: Food allergy disproportionately affects children and contributes to poor quality of life for families. As a result, accurate diagnosis of food allergy is important. Oral food challenges (OFC) are the gold standard test for diagnosis of food allergy. Yet, many children do not undergo OFCs. The purpose of this study was to understand the barriers to OFCs faced by parents of children with food allergies in Ontario, as well as solutions to increase their utilization.Methods: Three focus group discussions were carried out with a total of 24 parents of children with food allergies in Kitchener-Waterloo, Ontario. Focus group data were analyzed using constant comparative analysis.Results: Parents misperceived OFCs as management of food allergies. They were also unsure about whether OFCs take place in hospitals, clinics or in the home. Parents reported several barriers to OFCs including not being referred by their primary care physicians, wait times, and fear and anxiety. Additionally, parents with older children, children with multiple allergies and children who could only tolerate allergens in its baked form felt that OFCs would not improve their quality of life. Solutions offered by parents to increase uptake of OFCs included education of the public, physicians and policy makers to improve knowledge and training, and ensure timely access to OFCs. Parents also suggested a need for improved counselling about the risk of OFCs, psychological support, and sharing of patient success stories. Long-term follow-up after an OFC as well as support and guidance around food reintroduction was also suggested to ensure OFCs resulted in an improvement in quality of life.Conclusion: Interventions aimed at addressing barriers to OFCs identified by parents have the potential to increase utilization of OFCs, and thereby reduce the burden of food allergies in children and improve quality of life.


Author(s):  
Kathryn Ferris ◽  
Marianne Cowan ◽  
Christine Williams ◽  
Sinead McAteer ◽  
Caoimhe Glancy ◽  
...  

Food allergy is common, it can lead to significant morbidity andnegatively impacts on quality of life; therefore, it is vitally important we get the diagnosis right. However, making the diagnosis can be complex. Clinical history is the most important diagnostic tool and subsequent investigation may help confirm the diagnosis. The investigations available to most paediatric departments are skin prick testing and specific IgE so we will focus on these. Within this article we explore the evidence related to targeted testing and how to interpret these within the clinical context.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
C. Irani ◽  
G. Maalouly

Background. Food allergy (FA) is an important health problem in Western countries but there is limited data on the prevalence of food allergy in the Middle East. The main objective of our study is to assess the prevalence of self-reported food allergy in Lebanon. Methods. The survey was conducted by Telephone Calls questionnaire through random selection of landline phone numbers from the white pages all over Lebanon. A study questionnaire addressing the main objectives of the study was filled during the telephone call conversation. Results. Food allergy prevalence is estimated to be 4.1% in infants and children and 3.2% in adults. 65% of patients suffering from food allergy are females and 35% are males. Skin reactions are the most common symptoms among food allergy sufferers, reported in 86% of the cases. Signs of anaphylaxis appeared in 10.8% of cases. Fruits were the most common allergens at 35%, followed by eggs (19%) and nuts (16%). Cow’s milk and spices ranked fourth (14%). Only half of food allergy sufferers sought medical advice. Allergists, dermatologists, gastroenterologists, or GPs (general practitioners) were consulted. Blood testing for specific IgE was the main diagnostic tool used by physicians. Conclusion. This is a pilot study of self-reported food allergy prevalence in Lebanon based on telephone survey. General prevalence is estimated to be 4.1% in infants and children and 3.2% in adults. Our study may improve awareness for proper diagnosis, food elimination, and acquisition of epinephrine autoinjectors in this part of the world.


2021 ◽  
pp. 136749352110136
Author(s):  
Debbi Stockhammer ◽  
Connie H Katelaris ◽  
Maree D Simpson ◽  
Thiru Vanniasinkam

Health-related knowledge, skills and attitudes that translate to behaviours are important foundations for healthy living. However, deficiencies in any one of these factors have the potential to impact quality of life. This study investigates how Australian children perceive and manage their food allergy as they transition through childhood onto adolescence. To measure this, children aged 12 years and under completed an online survey [under 8 years and 8–12 years] on knowledge, skills and attitudes. Although recruitment involved advertisements to over 700 Australian pre-schools, 44 allergy specialists and multiple representations to the patient support group, Allergy & Anaphylaxis Australia, completion relied on parental notification and/or guidance. Of the 139 participants recruited, 114 commenced the survey with 65 participants under 8 years (58%) and 49 between 8 and 12 years. Results showed participants recognised different ways to keep safe with children under 8 years ( N = 65) 100% cognisant of the need to check with ‘Mum/Dad’ or teachers if they could safely eat food as well as the importance of not swapping lunches, while there was a slight change in compliance for those aged 8–12 years as three (6.1%, n = 3/49) children did not see the necessity of asking an adult/teacher if a food item was safe to eat. Older children were also less likely to tell friends about their food allergy even if they thought they were having an allergic reaction, despite children under 8 years more likely to feel different to friends (38%, n = 24/64) compared to those aged 8–12 years (31%, n = 14/45). Although both groups disliked parents’ fussing, for children under 8 years, there was a strong association between this and ‘feeling different to friends'. Results from this study highlight the importance of normalising food allergy at home and in the community, so children are confident in telling others about their food allergy.


2021 ◽  
Vol 49 (2) ◽  
pp. 15-22
Author(s):  
Judit Barrena Crespo ◽  
Marta Viñas Domingo ◽  
Nora Hernández Arauzo ◽  
M. José Castillo ◽  
M. Belén Delavalle ◽  
...  

Background: Multiple food allergies (MFAs) affect 30% of the child population with food allergy. The current treatment is the exclusion diet, which frequently affects the quality of life for these patients. The objective of the study was to describe the effect of omalizumab treatment in children diagnosed with MFAs who experienced frequent anaphylactic reactions and the impact on their quality of life.Material and methods: A descriptive observational study. Patients with severe food restrictions and high-risk due to multiple episodes of anaphylaxis were included. The allergy was confirmed by compatible clinical, skin tests, positive specific IgE and oral food challenges (OFCs). Omalizumab treatment was initiated and the impact on the life quality of patients and their families was assessed using the validated Food Allergy Quality of Life Questionnaire-Parent Form.Results: Five patients with an average age at diagnosis of 3.58 years (range between 1.5–7.9 years), were diagnosed with MFAs. All patients presented with anaphylaxis. All patients were treated with omalizumab between 2013 and 2019. Omalizumab treatment was initiated at a mean age of 6.05 years (range between 4.5–8.25 years). All patients have undergone OFC to reintroduce food successfully. 2 patients had their dose of omalizumab reduced by half, and 1 patient has had the time interval extended between administrations due to the maintenance of food tolerance. No immediate local or systemic adverse reactions were documented. Two patients have commenced omalizumab administration at home without incident.Conclusions: Children with MFAs who are treated with omalizumab do not show reactions in response to most of the foods to which they previously had anaphylaxis. Consequently, these patients were able to significantly expand the variety of their diet, improving the life quality and avoid anaphylaxis following the inadvertent intake of these foods.


2012 ◽  
pp. 63-87
Author(s):  
Anh Mai Ngoc ◽  
Ha Do Thi Hai ◽  
Huyen Nguyen Thi Ngoc

This study uses descriptive statistical method to analyze the income and life qual- ity of 397 farmer households who are suffering social exclusion in an economic aspect out of a total of 725 households surveyed in five Northern provinces of Vietnam in 2010. The farmers’ opinions of the impact of the policies currently prac- ticed by the central government and local authorities to give them access to the labor market are also analyzed in this study to help management officers see how the poli- cies affect the beneficiaries so that they can later make appropriate adjustments.


2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.


Sign in / Sign up

Export Citation Format

Share Document