scholarly journals Measures counteracting 2016 spread of vaccine-derived poliomyelitis virus type 2 in Russian Federation

2020 ◽  
Vol 10 (1) ◽  
pp. 90-98
Author(s):  
A. Yu. Popova ◽  
E. B. Ezhlova ◽  
A. A. Melnikova ◽  
N. S. Morozova ◽  
Yu. M. Mikhailova ◽  
...  
1952 ◽  
Vol 96 (4) ◽  
pp. 389-400 ◽  
Author(s):  
William F. Scherer ◽  
Jerome T. Syverton

Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the multiplication of this virus within them. Similarly, "fibroblasts" propagated in primary explant cultures of testicle were destroyed by poliomyelitis viruses, Types 1 and 2. Type specific antibodies neutralized the pathogenic effect of poliomyelitis virus on monkey testicular fibroblasts.


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